Clinical trials
Overweight and Obese Volunteers clinical trials
Below are recruiting overweight and obese volunteers clinical trials, each written for real people, not researchers. We’re tracking 25 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05770570RecruitingPhase 2
Diet and activity texting support for Mexican American drivers
This Phase 2 study tests a structured program using texts and recordings to help people improve diet and physical activity for weight loss. It focuses on specific Spanish-speaking groups and also includes a separate track for taxi/FHV drivers.
New York, New YorkAges 21 years+ - NCT06778850RecruitingPhase 1/Phase 2
Study of MDR-001 tablet for overweight or obese adults
This study tests a new tablet called MDR-001 for people who are overweight or obese. Researchers want to see if it is safe and helps with weight loss. You would take the tablet in different doses over several weeks.
Changchun, JilinAges 18–55 - NCT07578584RecruitingPhase 1
Safety study of NNC0497-0040 in healthy and overweight adults
This early-stage study tests a new investigational medication in three groups: healthy adults with normal weight, adults who are overweight or obese, and men with type 1 diabetes who are also overweight. The research aims to understand how safe the medication is and how the body processes it.
NeussAges 18–55 - NCT07253155Enrolling by invitation
Probiotics for preventing gut symptoms in overweight adults
This study tests whether taking probiotics can help prevent stomach and gut discomfort in people who are overweight or have obesity. You may be eligible if you are at a certain weight and age, eat a balanced diet, and do not have chronic gut issues.
ColeraineAges 18 years+ - NCT00428987Recruiting
Study of body and behavior traits in weight groups
This study looks at how physical traits and everyday behaviors differ among people who are overweight, obese, or in the normal-weight range. It may help researchers better understand risk factors related to weight and health.
Bethesda, MarylandAges 18–100 - NCT06742112Recruiting
Arm and Breathing Test for People Who Are Overweight
This study looks at how well people who are overweight or obese can use their arms and breathe while performing a 6-minute pegboard and ring test. Researchers want to see if this test can help measure physical function in this group.
KırşehirAges 18–65 - NCT07372157Recruiting
Balance exercises for people with overweight or obesity
This trial tests if neuromuscular balance exercises can help people who are overweight or obese. It aims to improve movement and stability.
Istanbul, IstanbulAges 18–65 - NCT07539415RecruitingPhase 1
Safety and effectiveness study of new injection in healthy adults
This study tests a new experimental injection in healthy volunteers to see if it's safe and how well the body absorbs it. Researchers will compare it with other similar treatments to understand how it works.
SeoulAges 19–64 - NCT06493084RecruitingPhase 1
Testing LAE102 in healthy and overweight adults
This study tests a new medicine called LAE102 in two groups: healthy volunteers and people who are overweight or obese. The goal is to see if it is safe and how the body processes it.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT05844644RecruitingPhase 2
Golo plan for weight and blood sugar in prediabetes
This trial tests whether the Golo for Life plan (with a release supplement) can improve blood sugar and help with weight in adults who have prediabetes or type 2 diabetes. If you join, you’ll follow the program and attend clinic visits while your health, diet, and weight are tracked.
LaSalle, OntarioAges 18–75 - NCT07165548Recruiting
Testing a special diet for weight and health in obesity
This trial tests whether a special diet with foods that make you feel full can help people with overweight or obesity lose weight and improve their heart, metabolic, and joint health.
Pamplona, NavarreAges 18–65 - NCT06759324Recruiting
Kombucha for weight: live vs. pasteurized effects
This study compares the effects of live kombucha versus pasteurized kombucha on gut health, metabolism, and liver function in people who are overweight or obese. Participants will drink kombucha daily for a set period to see if it improves their health.
Castelo Branco, Castelo Branco DistrictAges 18–60 - NCT07165431Recruiting
Postbiotic supplement study for overweight and obesity
This study tests whether taking a daily postbiotic gummy for 12 weeks can improve body composition and metabolic health in people with overweight or obesity. It may help if you have stable weight and no major health conditions like diabetes.
Pamplona, NavarreAges 18–70 - NCT06268262Recruiting
Obesity brain imaging study before and after surgery
This study uses brain scans to understand how obesity affects the brain and how bariatric surgery may change it. It compares people with obesity who are planning surgery to healthy volunteers.
Xuzhou, JiangsuAges 18–65 - NCT06786052RecruitingPhase 2
Study on after-meal energy in adults 50–70
This trial studies how a probiotic supplement affects energy use after meals in adults aged 50–70 who are overweight. You'll take either the probiotic or a placebo for several weeks.
Pierre-Bénite, Auvergne-Rhône-AlpesAges 50–70 - NCT06325722Recruiting
Low fat vs. low carb diet order and body fat change
This study compares how the order of low fat versus low carb diets affects body fat changes. It may help you understand which diet sequence works best for weight loss.
Bethesda, MarylandAges 18–50 - NCT06044935Recruiting
Nicotinamide riboside for fat burning and metabolism
This study tests whether a supplement called nicotinamide riboside (a form of vitamin B3) helps the body burn fat more efficiently during exercise. It may be a good option if you are overweight or have a specific type of diabetes (MODY2) and want to see if a natural supplement can boost your metabolism.
Bethesda, MarylandAges 18–65 - NCT07134335RecruitingPhase 2
Study of UBT251 injection for chronic kidney disease
This study tests an investigational injection called UBT251 for people with chronic kidney disease who are overweight. It aims to see if it can reduce protein in the urine and help protect kidney function.
BeijingAges 18–75 - NCT07415720Recruiting
Artichoke and Mediterranean diet to prevent type 2 diabetes
This study tests whether a special extract from artichoke by-products, combined with a Mediterranean diet, can help prevent type 2 diabetes in people who are at risk. It aims to improve how your body handles sugar and insulin.
Pamplona, NavarreAges 18–75 - NCT03851458Enrolling by invitationPhase 2
Spanish coaching for healthier food choices for weight
This Phase 2 study tests a program (with food guidance, text messages, and check-ins) to help people eat more healthfully. It is designed for adults who are overweight or obese and can speak Spanish (with some separate tracks for different groups).
New York, New YorkAges 18 years+ - NCT06487832Recruiting
Effect of diabetes drug on brain response to insulin
This study tests whether a GLP-1 receptor agonist (a type of diabetes medicine) changes how the brain responds to insulin in people with different body sizes. It may help understand if this drug can improve brain function related to insulin.
TübingenAges 18–70 - NCT06953232Recruiting
Protein drink for heart and brain in midlife women
This study tests a special protein drink (whey with milk fat globule membrane) to see if it helps your heart and brain after a high-fat breakfast. It might help you if you are a postmenopausal woman at moderate risk for heart disease.
Loughborough, LeicestershireAges 50–75 - NCT06994338RecruitingPhase 2
Tirzepatide for alcohol use disorder
This study tests whether a medication called tirzepatide (a once-weekly injection) can help people reduce their alcohol consumption. It is for people who drink heavily, have a high BMI, and are actively seeking help to drink less.
Los Angeles, CaliforniaAges 21–65 - NCT07065643Recruiting
Calorie restriction study for healthy overweight adults
This study looks at how sex hormones affect the benefits of a low-calorie diet in men and women of different ages. If you are a healthy overweight adult, the study may help understand how hormones and age influence weight loss results.
AberdeenAges 18–65
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Common questions
- Are there clinical trials for overweight and obese volunteers?
- Yes. Clin2 currently lists 25 recruiting overweight and obese volunteers studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight and obese volunteers trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight and obese volunteers trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.