Clinical trials
Overweight or Obese clinical trials
Below are recruiting overweight or obese clinical trials, each written for real people, not researchers. We’re tracking 1,536 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07254065Recruiting
Preventing obesity early with telehealth support
This study tests a telehealth program to help prevent obesity in pregnant women. It offers support and education through video calls to promote healthy habits.
New Hyde Park, New YorkAges 18 years+ - NCT07031297Recruiting
Exosome release after a meal in obesity
This study looks at how the body releases tiny particles called exosomes from the upper arm after a meal, specifically in women with obesity. It helps researchers understand how fat tissue responds to eating.
Rochester, MinnesotaAges 18–55 - NCT07744022Recruiting
Exercise comparison for children with obesity
This study compares two types of exercise programs — progressive neuromuscular stabilization exercises versus aerobic exercises — to see which one better improves body composition and balance in children with obesity. It aims to find a fun, effective way to help kids move better and feel healthier.
IstanbulAges 12–18 - NCT07693426RecruitingPhase 1
Study of efsubaglutide alfa for obese teenagers
This trial tests an injection called efsubaglutide alfa to help obese teenagers lose weight. It requires following diet and exercise advice for at least 3 months before starting.
Beijing, Beijing MunicipalityAges 12–17 - NCT07736547Enrolling by invitation
AI-guided supplement for weight loss
This study tests a nutritional supplement (guided by your gut bacteria) to help with weight loss, along with lifestyle advice. It might be a good fit if you are overweight but not diabetic and have not used weight-loss medications recently.
IstanbulAges 18–65 - NCT03514602Recruiting
Help quitting smoking to prevent childhood obesity
This study supports pregnant people who smoke to quit or cut down, using behavior-based coaching. It also measures how changes in smoking may help lower a child’s risk of developing obesity.
Buffalo, New YorkAges 18–39 - NCT06199154RecruitingEarly Phase 1
Inducing labor in women with severe obesity
This study tests starting labor in women with a BMI of 40 or higher. The goal is to learn if certain methods are safe and effective for this group.
Baltimore, MarylandAges 18 years+ - NCT07702890RecruitingPhase 1/Phase 2
Testing a new drug for obesity and type 2 diabetes
This trial tests an investigational drug called GUB-UCN2 in people who are healthy, overweight, or have type 2 diabetes. The goal is to see if the drug is safe and how the body processes it.
NeussAges 18–75 - NCT07731438Recruiting
Calorie restriction and bone marrow fat in obesity and diabetes
This study tests whether a calorie-restricted diet can change the fat in your bone marrow and how it relates to bone health and energy use. It is for premenopausal women and men who are either obese or lean and do not have diabetes.
PragueAges 21–55 - NCT05219799RecruitingEarly Phase 1
Study breathing and blood vessel responses in adults with obesity
This early study tests how your body’s blood vessels respond when oxygen levels are lower, and whether body weight changes that response. You may be able to join if you’re not pregnant and meet health, blood pressure, and breathing/smoking criteria.
Columbia, MissouriAges 18–45 - NCT07496463Enrolling by invitationPhase 2
Setmelanotide for weight loss in pseudohypoparathyroidism type 1a
This study tests an experimental medication called setmelanotide to see if it can help with weight loss in people who have pseudohypoparathyroidism type 1a (PHP1a), a rare genetic condition that often leads to obesity. The goal is to find a new treatment option for weight problems related to PHP1a.
Boston, MassachusettsAges Any age - NCT07284979RecruitingPhase 3
Weekly injection for obesity without diabetes
This trial tests a new once-weekly injection called Ribupatide for weight loss in people with obesity who do not have diabetes. It compares the study drug to an existing medication (semaglutide) and a placebo to see how well it works and if it's safe.
Glendale, ArizonaAges 18 years+ - NCT06497595Recruiting
Lifestyle program to prevent muscle loss in older adults with diabetes on semaglutide
This trial tests whether a lifestyle program (diet and exercise) can help prevent muscle loss in people 65 and older with type 2 diabetes and obesity who are taking semaglutide. It may help you keep your strength and independence while losing weight.
Jerusalem, IsraelAges 65 years+ - NCT04714892Recruiting
Taste and smell differences in obesity
This study looks at how taste and smell may differ in people with obesity compared to healthy-weight individuals. It aims to understand why some people perceive flavors differently, which could help develop better treatments for weight management.
Bethesda, MarylandAges 18–65 - NCT06924177Recruiting
Spinal cord injury diet study for wheelchair users
This study tests a special diet program for people with spinal cord injuries who use a wheelchair. It aims to see if the diet can improve health and well-being.
Dallas, TexasAges 18–65 - NCT03022682Recruiting
Study of inflammation and metabolism across diabetes and weight
This is an observational study that follows generally healthy adults to understand how inflammation, diabetes (type 2), and weight/metabolic health relate to each other. It may help researchers figure out why different groups (including different ethnic backgrounds) have different health risks.
San Francisco, CaliforniaAges 18–75 - NCT03135730Recruiting
ROHHAD patient registry for rapid-onset obesity
This study is a registry that collects information from people diagnosed with, or suspected to have, ROHHAD. It can help researchers better understand the condition over time and improve future care.
Chicago, IllinoisAges Any age - NCT03152617Recruiting
Study on nutrition and mouth health risks after obesity treatment
This trial looks at risks like malnutrition, weak bones, and oral (mouth) health problems after obesity treatment. It may help improve follow-up care for people who receive specialist treatment or weight-loss surgery.
GothenburgAges 18 years+ - NCT03302195Recruiting
Heparin and bypass blood management for obese heart surgery
This trial studies the best way to manage blood thinning (anticoagulation) during heart surgery that uses a heart-lung machine in people with obesity. It may help reduce blood-clotting and bleeding complications by comparing different care strategies.
Québec, QuebecAges 18 years+ - NCT03402139Recruiting
Study early-life obesity risk after growth restriction
This study looks at how obesity risk may be influenced in children whose growth was lower than expected before birth. It enrolls mothers and babies together to learn whether early childhood obesity programming can help families.
The Bronx, New YorkAges 1 hour–2 years - NCT03472157Recruiting
Bariatric surgery for severe NASH with advanced liver scarring
This study tests whether bariatric surgery (either sleeve gastrectomy or Roux-en-Y gastric bypass) improves severe nonalcoholic steatohepatitis (NASH) with advanced liver scarring in people who are obese. You may also need liver biopsies to confirm your liver disease before and after treatment.
LilleAges 18–65 - NCT03516968RecruitingPhase 3
Monthly vs daily vitamin D for obese children
This study compares taking vitamin D as a monthly dose versus a daily dose in children with low vitamin D levels. It aims to correct the vitamin D deficiency and see which schedule works best and is safe.
BronAges 5–18 - NCT03756961Recruiting
Opioid-free care plan for people having weight-loss surgery
This trial studies whether an opioid-free or opioid-sparing care pathway can improve comfort and outcomes for adults undergoing laparoscopic weight-loss surgery. It may help people avoid side effects from opioid pain medicines while still managing pain safely.
Lindesberg, Region ÖrebroAges 18 years+ - NCT03821636Recruiting
Compare gastric bypass limb lengths for type 2 diabetes remission
This study looks at whether a gastric bypass surgery with a longer intestine segment or a longer bile drainage segment leads to better type 2 diabetes remission in people with severe obesity. It may help doctors choose the most effective surgical approach and follow-up plan for diabetes improvement.
AmiensAges 18–60
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Common questions
- Are there clinical trials for overweight or obese?
- Yes. Clin2 currently lists 1,536 recruiting overweight or obese studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.