Clinical trials · Chicago, IL
Overweight or Obesity clinical trials in Chicago
We’re tracking 59 recruiting overweight or obesity studies with a site in or near Chicago — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Chicago
- NCT07654361RecruitingPhase 3
A new pill for weight loss in obesity and overweight
This study tests an investigational pill called aleniglipron to see if it helps people with obesity or overweight who also have a weight-related health problem (like high blood pressure) lose weight safely. It is a Phase 3 trial, meaning it is in the final stages before seeking approval.
Chicago, IllinoisAges 18–79 - NCT07392190RecruitingPhase 3
Study of eloralintide for people with persistent obesity
This trial tests if adding eloralintide helps people who are still obese or overweight while taking weekly incretin therapy. It aims to support additional weight loss for those who haven't reached their goals.
Chicago, IllinoisAges 18 years+ - NCT06636058Recruiting
Digital treatment for weight and mood in adults 50+
This study tests a digital program that helps with weight loss and depression at the same time. It is designed for Black, Hispanic, and other adults over 50 who carry extra weight and feel down.
Chicago, IllinoisAges 50–74 - NCT05918575Recruiting
Breathing support after a breathing tube in very obese adults
This trial tests whether giving noninvasive breathing support (using a mask or similar device, without a new breathing tube) right after removing a breathing tube works better for severely obese adults. It mainly looks at people at higher risk of needing help breathing again after extubation.
Chicago, IllinoisAges 18 years+ - NCT07332741RecruitingPhase 2
Food as medicine for better blood pressure
This study tests a program that provides healthy food and support to help people with high blood pressure and a BMI of 30 or higher eat better and control their blood pressure. If you join, you'll get guidance on the DASH diet (a heart-healthy eating plan) and text messages to help you stay on track.
Chicago, IllinoisAges Any age - NCT07567001RecruitingPhase 3
Testing NNC0487-0111 for Heart Failure and Obesity
This study tests whether a new medication called NNC0487-0111 can help people with heart failure who also have obesity. Researchers will compare it to a placebo (inactive pill) to see if it improves heart function and overall health.
Chicago, IllinoisAges 18 years+ - NCT07571109RecruitingPhase 3
Weight Loss Medicine for Sleep Apnea on CPAP
This study tests a new injectable medicine (NNC0487-0111) to help people lose weight and improve obstructive sleep apnea (a breathing condition during sleep). You must already be using a CPAP machine (positive airway pressure device) for your sleep apnea.
Chicago, IllinoisAges 18 years+ - NCT06760546RecruitingPhase 3
Testing setmelanotide for weight gain after brain injury
This trial tests a daily injection called setmelanotide to see if it can help people who have gained weight due to a brain injury or condition affecting the hypothalamus. It may help reduce hunger and support weight loss.
Chicago, IllinoisAges 4 years+ - NCT07668414RecruitingPhase 3
Study comparing Zenagamtide and Semaglutide for weight loss
This trial tests a new medicine Zenagamtide to see if it helps people with excess weight lose more weight than Semaglutide, an existing weight loss drug. You may join if you are an adult with overweight or obesity but do not have diabetes.
Chicago, IllinoisAges 18 years+ - NCT06390345Recruiting
Telehealth lifestyle and exercise for COPD and sleep apnea
This study tests a telehealth program that combines lifestyle coaching and exercise to help people with both COPD and sleep apnea improve their breathing and daily function. It may be a good fit if you are overweight, have a history of smoking, and feel short of breath during light activity.
Chicago, IllinoisAges 18 years+ - NCT07564414RecruitingPhase 3
Weight Loss Study Comparing Two Doses of CagriSema
This study tests whether a new combination medication called CagriSema (in two different doses) helps people with obesity lose weight. You may qualify if you're 18 or older, have a BMI of 35 or higher, and either don't have type 2 diabetes or have it well-controlled.
Chicago, IllinoisAges 18 years+ - NCT07288294Recruiting
Primary care strategies for weight management after stopping medication
This study looks at different ways to help you keep weight off after you stop taking a weight loss medication. You will work with your primary care team to learn healthy habits and get support without the drug.
Chicago, IllinoisAges 18 years+ - NCT03135730Recruiting
ROHHAD patient registry for rapid-onset obesity
This study is a registry that collects information from people diagnosed with, or suspected to have, ROHHAD. It can help researchers better understand the condition over time and improve future care.
Chicago, IllinoisAges Any age - NCT07752979RecruitingPhase 2
New drug for weight loss in adults with obesity or overweight
This study tests an investigational drug called ABBV-295 to see if it helps adults with obesity or overweight who have weight-related health conditions lose weight. It may offer a new treatment option for managing weight and improving overall health.
Chicago, IllinoisAges 18–75 - NCT05687604Recruiting
Telehealth program to reduce cancer risk behaviors
This trial offers a scalable telehealth (phone/video) program to help people improve cancer risk habits like low physical activity, higher body weight, and smoking. It may help by giving structured coaching and support in the privacy of your home.
Chicago, IllinoisAges 18 years+ - NCT07720271RecruitingPhase 3
Zenagamtide weight loss study for adults
This study is testing a new tablet called Zenagamtide to help people with extra body weight lose weight. It's for adults who are not diabetic and haven't used similar weight loss drugs before.
Chicago, IllinoisAges 18 years+ - NCT07776509RecruitingPhase 3
Adding a new drug to current weight-loss therapy for adults with obesity or overweight
This study tests a new medication (AZD6234) added to your current weight-management medication (an incretin-based drug) to see if it helps with weight loss. You may be eligible if you are overweight or obese with related health issues or type 2 diabetes.
Chicago, IllinoisAges 18 years+ - NCT07798557Recruiting
Lifestyle and diet support for weight and heart health
This study tests a program to help you improve your diet and lifestyle, which may reduce your risk for heart disease and help with weight loss. You will get support to make healthy changes over the next year.
Chicago, IllinoisAges 50–79 - NCT07794579RecruitingPhase 3
Study of orforglipron for people with overweight at risk of health problems
This trial tests a new medicine, orforglipron, to help people with overweight who are at risk of developing weight-related health issues. It aims to see if the medicine can help with weight management and reduce risks before more serious conditions develop.
Chicago, IllinoisAges 18 years+ - NCT07789769Recruiting
Online weight loss program focusing on protein, fiber, and exercise
This study tests a 6-month online weight loss program that focuses on eating more protein and fiber and adding exercise—called the '30-30-30 Plan.' It's a chance to get support and guidance to help you reach your weight loss goals.
Chicago, IllinoisAges 18–69 - NCT07817875RecruitingPhase 3
Tirzepatide for weight loss in children aged 6 to under 12
This study tests a once-weekly medication called tirzepatide to help children aged 6 to under 12 with obesity lose weight. It compares the medication to a placebo (inactive shot) to see if it safely helps with weight loss in this age group.
Chicago, IllinoisAges 6–11 - NCT06672939RecruitingPhase 3
Orforglipron for Weight Loss in Teens
This study tests a once-daily pill (orforglipron) to help adolescents with obesity or overweight plus related health problems lose weight. It offers a new option for teens who have struggled to lose weight with diet and exercise alone.
Chicago, IllinoisAges 12–17 - NCT07685808RecruitingPhase 2
Testing a weight loss injection for people with overweight or obesity
This study tests an injectable medication called Olatorepatide to help people with overweight or obesity lose weight. It is only for people without diabetes who meet specific body mass index (BMI) requirements.
Chicago, IllinoisAges 18 years+ - NCT05234125Recruiting
Lifestyle counseling during pregnancy for African American women
This trial tests a better lifestyle counseling program during pregnancy to help improve health—especially for women who started pregnancy at a higher weight. It may help you learn practical changes for a healthier pregnancy and outcomes.
Chicago, IllinoisAges 18–40
Hear when a new Overweight or Obesity trial opens near Chicago, IL
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Overweight or Obesity trials in other cities
Where these studies are running near Chicago
Institutions with a site for the recruiting overweight or obesity studies listed above.
- Ann & Robert H. Lurie Children's Hospital of Chicago · 3 studies
- Endeavor Health · 3 studies
- Chicago Research Center, Inc · 2 studies
- Clinical Investigation Spec Gurnee · 2 studies
- Evanston Premier Hlthcr Res · 2 studies
- Great Lakes Clinical Trials · 2 studies
- Rush University Medical Center · 2 studies
- University of Illinois at Chicago · 2 studies
What taking part in a overweight or obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting overweight or obesity studies in Illinois.
Common questions
- Are there overweight or obesity clinical trials near Chicago?
- Yes. We're currently tracking 59 recruiting overweight or obesity studies with a site near Chicago, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a overweight or obesity study near Chicago?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Chicago to take part?
- Not necessarily. These studies have a site near Chicago, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New overweight or obesity studies open near Chicago regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.