Clinical trials · California
Overweight or Obesity clinical trials in California
We’re tracking 119 recruiting overweight or obesity studies with a site in California — including Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07209202Recruiting
Study on Fructose Handling in Obesity
This study looks at how the body handles fructose (a natural sugar) in people with different weights. It may help explain why some people process sugars differently.
Vallejo, CaliforniaAges 20–55 - NCT06207110Recruiting
Family support program for children with high food responsiveness
This study tests a program for families with children ages 7–12 who have overweight or obesity and often feel strong urges to eat. The program helps parents support their child in eating healthier and being more active.
La Jolla, CaliforniaAges 7–12 - NCT06934655RecruitingPhase 3
Starting semaglutide again after weight-loss surgery in teens
This trial tests if restarting semaglutide (a weekly injection for weight loss) soon after sleeve gastrectomy helps teens with severe obesity keep losing weight. It is for patients who were already taking semaglutide before their surgery.
Los Angeles, CaliforniaAges 12–18 - NCT06897982Recruiting
Nutrition program for prediabetes at health center
This study tests a nutrition program for people with prediabetes at a health center. It aims to see if the program is practical and can help prevent type 2 diabetes.
Los Angeles, CaliforniaAges 18–99 - NCT06783751Recruiting
New surgical method to reduce acid reflux after weight loss surgery
This trial tests a modified version of sleeve gastrectomy that aims to reduce the risk of acid reflux (GERD) after surgery. It is for people aged 18–65 with a BMI between 35 and 55 who already have some degree of GERD and are planning to have weight loss surgery.
Orange, CaliforniaAges 18–65 - NCT06715787Recruiting
Perinatal support program for pregnant people
This trial tests a support program for pregnant individuals who qualify for certain food assistance benefits. It aims to see if the program helps with pregnancy and infant health.
Los Angeles, CaliforniaAges 18 years+ - NCT06596902Recruiting
Physical activity program for Latino families near the U.S.-Mexico border
This trial tests a program to help Latino families become more active and fit. It takes place at community centers near the border and includes both parents and children.
San Diego, CaliforniaAges 6 years+ - NCT06544954Recruiting
Grape study for heart and gut health in overweight women
This study tests whether eating California grapes can improve gut health and heart health in overweight or obese women who have been through menopause and may have type 2 diabetes or metabolic syndrome. You would need to eat grapes daily and provide blood and stool samples.
Davis, CaliforniaAges 45–70 - NCT06230510Recruiting
Whole vs. low-fat milk study for toddlers
This study compares the health effects of drinking whole milk versus 1% low-fat milk for one year in children aged 23 to 48 months. Researchers want to see which type of milk is better for growth and overall health.
Oakland, CaliforniaAges 1.9 years–4 years - NCT06032104Recruiting
Bean supplement study for colon cancer screening patients
This trial tests whether adding a daily bean supplement to your diet can improve colon health. You may be eligible if you are between 30 and 80, overweight, and scheduled for a routine colonoscopy.
Sacramento, CaliforniaAges 30–80 - NCT06051591Recruiting
Food FARMacia: Helping families with food worries
This study tests a program called Food FARMacia to help families with young children who sometimes worry about having enough food. The goal is to see if the program can help prevent childhood obesity by providing support and resources.
Stanford, CaliforniaAges 6 months+ - NCT05975580RecruitingPhase 4
Medication plus lifestyle counseling for weight regain after bariatric surgery
This study looks at whether adding medication to lifestyle counseling can help people who have regained weight after sleeve gastrectomy or gastric bypass. It focuses on improving weight control and related health after surgery.
Orange, CaliforniaAges 18–70 - NCT05653258RecruitingPhase 2/Phase 3
Study cells in fat tissue and aging cells in older adults
This study uses a special lab test on tiny samples from body fat to map different cell types and “senescent” (aging) cells. It may help researchers understand how aging and obesity are linked, which could guide future treatments.
Los Angeles, CaliforniaAges 18 years+ - NCT05589155Recruiting
Using a phone app to improve blood sugar and weight
This study looks at whether a mobile phone app can help people with type 2 diabetes improve their health habits, including blood sugar monitoring and weight. You may be able to join if you already check your blood sugar daily and are able to use a smartphone.
San Diego, CaliforniaAges 18–64 - NCT05279729Recruiting
Mobile app coaching for people with diabetes
This study tests whether using a smartphone app can help people with type 2 diabetes manage their health. It focuses especially on low-income Hispanic/Latinx adults who regularly check blood sugar.
San Diego, CaliforniaAges 18–64 - NCT05173714RecruitingPhase 2
Sit Less and Move More program for people with CKD
This Phase 2 study tests a program to help people with chronic kidney disease (CKD) sit less and move more, plus a medication (semaglutide) for those who qualify. It may help improve health and day-to-day activity while monitoring safety closely.
Stanford, CaliforniaAges 20 years+ - NCT05082519RecruitingPhase 2
Calorie restriction and exercise to improve leukemia treatment in young patients
This study tests whether a special diet (calorie restriction) and increased physical activity can make chemotherapy work better for young people with B-ALL. Participants will follow a monitored diet and exercise plan during their first month of treatment.
Orange, CaliforniaAges 7–25 - NCT04913064Recruiting
White button mushroom supplement for inflammation in high-risk breast cancer
This trial tests whether a white button mushroom powder supplement can lower inflammation in postmenopausal women who have a high risk of breast cancer. If it helps, it could improve early prevention strategies for people at higher risk.
Duarte, CaliforniaAges 21 years+ - NCT04997473Recruiting
Mobile app weight-loss program for young transplant patients
This trial tests whether a phone app can help young people who previously had a stem cell transplant lose weight. It’s designed for people who are at least 100 days out from transplant and who meet weight criteria.
Los Angeles, CaliforniaAges 13–30 - NCT04708535Enrolling by invitation
Study how fat changes affect insulin resistance after bariatric surgery
This study looks at how your body’s fat under the skin and inside the abdomen may affect “insulin resistance,” a common problem linked with blood sugar control. It’s for people who are scheduled for bariatric (weight-loss) surgery, to learn more before and after surgery.
Stanford, CaliforniaAges 30–65 - NCT04453072Recruiting
iPhone weight-loss app for teens and young adults after transplant
This study tests whether an iPhone weight-management app can help adolescents and young adults lose weight after a stem cell transplant. If you qualify, you’ll use the app and the team will track changes in weight.
Los Angeles, CaliforniaAges 13–30 - NCT04248127Recruiting
Honey yogurt to improve gut health and mild inflammation
This study tests whether honey-flavored yogurt can improve gut health and “low-grade” inflammation in middle-aged and older women after menopause. You may be asked to follow a yogurt-focused plan and avoid certain foods or supplements to see the effect.
Davis, CaliforniaAges 45–65 - NCT02024542Recruiting
How the body changes after bariatric surgery
This study looks at how metabolism (how your body handles food and energy) responds after weight-loss surgery. It may help researchers understand what changes to expect in people with diabetes or prediabetes and cholesterol problems.
Sacramento, CaliforniaAges 18–55
Overweight or Obesity trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting overweight or obesity studies listed above.
- San Diego State University · 3 studies
- Cedars-Sinai Medical Center · 2 studies
- Children's Hospital Los Angeles · 2 studies
- Stanford University · 2 studies
- University of California, Irvine · 2 studies
- Children's Hospital Orange County
- City of Hope
- Nutrition Policy Institute, University of California Agriculture and Natural Resources
What taking part in a overweight or obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Overweight or Obesity trials in other states
Common questions
- Are there overweight or obesity clinical trials in California?
- Yes. We're currently tracking 119 recruiting overweight or obesity studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a overweight or obesity study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New overweight or obesity studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.