Clinical trials
Overweight or Obesity clinical trials
Below are recruiting overweight or obesity clinical trials, each written for real people, not researchers. We’re tracking 1,527 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07750223Recruiting
Hesperidin for memory and thinking in older adults
This study tests whether a natural supplement called hesperidin (found in citrus fruits) can support brain health in older adults who are overweight or obese. It may help with memory and thinking.
Shanghai, Shanghai MunicipalityAges 55–75 - NCT07748949Recruiting
Low-calorie diet and lifestyle help for type 2 diabetes
This study tests whether a low-calorie diet combined with a personalized lifestyle program can help people with type 2 diabetes reach remission, meaning their blood sugar stays normal without needing diabetes medication. It uses a smartphone app to support the program.
BangkokAges 18–70 - NCT07153471RecruitingPhase 3
A study of an experimental pill for weight loss and knee arthritis
This trial tests an investigational medication (orforglipron) to see if it helps people with knee arthritis lose weight. You may qualify if you have overweight or obesity and have tried dieting before without lasting success.
Phoenix, ArizonaAges 18 years+ - NCT07629544RecruitingPhase 3
Testing DA-302168S for weight loss in overweight and obese adults
This study tests a new medication called DA-302168S to help people lose weight. You may qualify if you're overweight or obese and meet certain health requirements.
BeijingAges 18–75 - NCT07202884RecruitingPhase 3
Orforglipron for Women with Stress Incontinence and Overweight
This study tests an oral medication called orforglipron to see if it helps women with stress urinary incontinence who are also overweight or have obesity. The medicine may reduce leaking episodes and also help with weight loss.
Birmingham, AlabamaAges 18 years+ - NCT07667803RecruitingPhase 3
Study of elecoglipron for weight loss in obesity or overweight
This trial tests an investigational drug called elecoglipron to see if it helps people with obesity or overweight lose weight. It may be an option if you have a high body mass index or weight-related health issues like high blood pressure or prediabetes.
Birmingham, AlabamaAges 18 years+ - NCT05943626Recruiting
Sleep timing changes to improve heart and blood sugar health
This study tests whether changing your sleep habits can improve heart-related health and blood sugar control. You may be asked to follow a sleep schedule and other routines, and outcomes will be measured over time.
Salt Lake City, UtahAges 18–45 - NCT07743567Recruiting
Weight and pregnancy outcomes after GLP-1 use
This study looks at how a type of weight-loss medication called GLP-1 affects pregnancy and baby outcomes. It aims to learn if this medication is safe to use early in pregnancy.
Kansas City, KansasAges 18–45 - NCT07684235RecruitingPhase 3
Long-term study of a weight-loss drug for trial graduates
This study tests a drug called Maridebart Cafraglutide for long-term weight management in people who completed a previous related trial. It looks at how well the drug works and its safety over time.
Daphne, AlabamaAges 18–99 - NCT07740291Recruiting
Tirzepatide and lifestyle study for weight loss
This trial compares two ways to manage weight: taking a GLP-1 medication (like tirzepatide or semaglutide) versus making lifestyle changes without medication. It will help researchers learn which approach works best for people with overweight or obesity.
Lubbock, TexasAges 18 years+ - NCT07619989Recruiting
Ear nerve stimulation for weight loss after tirzepatide
This trial tests if a gentle electrical stimulation to the ear can help people who haven't lost much weight with tirzepatide (a diabetes/weight drug). It's for people who are still overweight after 12 weeks of treatment.
Nanjing, JiangsuAges 18–50 - NCT06619041Recruiting
HealthyTogether: Weight Management with a Partner
This study tests a weight management program where you and a partner (like a spouse or friend) work together virtually. It aims to help you lose weight and improve health habits alongside someone you trust.
Aurora, ColoradoAges 18 years+ - NCT07738029Recruiting
Intensive lifestyle treatment for children with obesity and their families
This trial studies a 1-year intensive lifestyle program for children ages 10-16 with a high body mass index (ISO-BMI ≥30) and their families. It aims to help children who have struggled to lose weight with lifestyle changes alone.
Tampere, PirkanmaaAges 10–16 - NCT07728669Recruiting
Digital diet app for people on GLP-1 therapy
This study tests a smartphone app that gives dietary advice to people who are overweight or obese and also take a GLP-1 medication (like semaglutide) for weight or diabetes. The app will help you follow a healthy eating plan while using the medication.
AlmatyAges 21–65 - NCT07724340RecruitingPhase 2
Study of AT673 plus semaglutide for type 2 diabetes and weight loss
This study tests a new medication called AT673 combined with semaglutide (Wegovy) to help people with type 2 diabetes and overweight or obesity lose weight and improve blood sugar. It is for people who have tried diet and exercise to lose weight but haven't had success.
Chandler, ArizonaAges 18 years+ - NCT06282952Recruiting
Stool transplant for C-section babies' health
This trial tests whether giving a special stool transplant (fecal microbiota) to healthy babies born by C-section can improve their health. It aims to see if this treatment helps replace good bacteria that are normally passed during a vaginal birth.
OuluAges birth–6 hours - NCT07717658Recruiting
Family weight wellness program for teens and parents
This study tests a weight wellness program that uses food support and group medical visits for teens and their parents. It aims to help families adopt healthier habits together over 12 months.
Boston, MassachusettsAges 12–17 - NCT05503927Enrolling by invitation
Study of Wegovy safety during pregnancy
This study looks at health outcomes for pregnant women and their babies after taking Wegovy or other weight-loss medicines. It may help understand if these medicines are safe during pregnancy.
Ann Arbor, MichiganAges 15–50 - NCT06147973Recruiting
Healthy lifestyle program for teen girls
This study tests a healthy lifestyle program that helps teen girls accept their bodies and make positive changes. It aims to see if this approach can improve weight-related health and well-being.
Philadelphia, PennsylvaniaAges 14–19 - NCT07253285RecruitingPhase 3
Study on cagrilintide and CagriSema for kids with excess weight
This trial tests two new medicines (cagrilintide and CagriSema) to see if they help children and teens lose weight. It's for young people who have tried lifestyle changes without enough success.
Escondido, CaliforniaAges 8–18 - NCT07409831Recruiting
Incretin drugs, diet, and exercise for weight loss
This trial tests whether combining a new type of weight-loss medication with nutrition advice and physical activity helps people with obesity lose more weight. It’s for adults who are about to start an incretin-based drug for the first time.
Québec, QuebecAges 18–70 - NCT07539415RecruitingPhase 1
Safety and effectiveness study of new injection in healthy adults
This study tests a new experimental injection in healthy volunteers to see if it's safe and how well the body absorbs it. Researchers will compare it with other similar treatments to understand how it works.
SeoulAges 19–64 - NCT07707778Enrolling by invitationPhase 4
Tirzepatide for Weight and Aging in People with HIV
This trial tests whether a weight-loss medicine called tirzepatide can slow biological aging and improve metabolism in people with HIV who are already on effective treatment. It may help you reduce weight and possibly reverse some signs of aging.
TaipeiAges 18 years+ - NCT05681468Recruiting
Ketogenic diet trial for blood sugar and inflammation outcomes
This study compares two versions of a ketogenic (very low-carb) diet to see how they affect blood sugar control and inflammation. It may help people with overweight or obesity who have pre-diabetes-level blood sugar understand which fat sources work better.
Edmonton, AlbertaAges 18–70
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Common questions
- Are there clinical trials for overweight or obesity?
- Yes. Clin2 currently lists 1,527 recruiting overweight or obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.