Clinical trials
Overweight clinical trials
Below are recruiting overweight clinical trials, each written for real people, not researchers. We’re tracking 532 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06938269RecruitingPhase 1
Study of MWN109 tablets in healthy adults
This trial tests a new tablet called MWN109 in healthy adults to see how safe it is and how the body handles it. It has two parts: one for people with a wide range of body weights, and another specifically for people with higher body weight. The results will help guide future studies.
Adelaide, South AustraliaAges 18–60 - NCT06934408RecruitingPhase 1
Safety study of HRS-5817 injection in healthy adults
This early-phase trial tests the safety and tolerability of a new injection called HRS-5817 in healthy volunteers. It helps researchers understand how the drug moves through the body and what side effects it might have.
Hefei, AnhuiAges 18–55 - NCT06923735Enrolling by invitation
Nutrition app pilot for employee health checks
This pilot study tests a nutrition app to help employees manage conditions like high cholesterol, high blood pressure, weight issues, or type 2 diabetes. It is part of your regular occupational health check or dietitian visit.
KuopioAges 18–75 - NCT06923644Recruiting
Personalized nutrition plan to prevent metabolic disease
This study tests whether a personalized nutrition plan based on your unique metabolism can help prevent chronic metabolic diseases like type 2 diabetes. You will follow a tailored diet and have your health monitored over time.
MaastrichtAges 40–75 - NCT06923865Enrolling by invitation
Exercise program for overweight teens
This trial tests whether a supervised exercise program can improve movement skills and motivation in overweight adolescents. It is designed for teens who struggle with physical activity but are otherwise healthy.
BaselAges 12–14 - NCT06924320RecruitingPhase 1/Phase 2
Study of two medicines for weight loss and diabetes
This study tests two investigational medications, MET233 and MET097, in people with obesity or overweight, with or without type 2 diabetes. It aims to see if the combination can help with weight loss and blood sugar control.
Cypress, CaliforniaAges 18–75 - NCT06903455Enrolling by invitation
Dance program for heart health in Indigenous women
This study tests a culturally designed dance program for Indigenous women who are overweight or obese. It aims to improve heart health by making exercise fun and meaningful.
Padre Las Casas, AraucaniaAges 18–80 - NCT06893016RecruitingPhase 3
Study of RAY1225 for adults with obesity or overweight
This trial tests a new medicine called RAY1225 to help people lose weight. If you have obesity or are overweight with related health conditions, you may be able to join.
BeijingAges 18 years+ - NCT06455878Recruiting
Mobile app for weight loss in heart failure patients
This trial tests a mobile app that helps you track your diet to manage your weight. It is designed for people with heart failure who are overweight and have recently been in the hospital for their condition.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06570642Recruiting
Study on emotions and physical activity
This study looks at how emotions affect your desire to be active. You'll wear a Fitbit smartwatch and answer short surveys to help researchers understand what helps people start and stick with physical activity.
Los Angeles, CaliforniaAges 18 years+ - NCT06891352Recruiting
Timing meals to reduce disease risk in night shift workers
This study tests whether adjusting when you eat (time-restricted eating) can improve health in night shift workers. You would use a smartphone app to track your meals and follow a set eating schedule for up to a year.
La Jolla, CaliforniaAges 18–70 - NCT06857929Recruiting
Nutrition study for metabolic syndrome
This study tests whether a personalized nutrition plan can improve health and lower the risk of chronic diseases like diabetes and heart disease in middle-aged adults with metabolic syndrome.
Madrid, MadridAges 30–50 - NCT06861868Recruiting
Brain and behavior's role in childhood obesity
This study looks at how the brain and behavior contribute to obesity from infancy through childhood. It may help researchers understand why some children develop obesity and how to prevent it.
Baltimore, MarylandAges 7–12 - NCT06859697Enrolling by invitation
Herbal medicine for obesity with spine or joint pain
This trial tests whether herbal medicine can safely help with pain and weight loss in people who have both obesity (BMI 25 or higher) and back or joint pain. It aims to see if the treatment works and is safe.
Seoul, Gangnam-GuAges 19–69 - NCT06855784Recruiting
Time-Restricted Eating for Menopause and Breast Cancer
This study tests if time-restricted eating (eating only during a set window each day) can help women with menopausal symptoms, including those who have had hormone-sensitive breast cancer and are on hormone-blocking therapy.
Geneva, Canton of GenevaAges 45–60 - NCT06847399RecruitingPhase 2
Tirzepatide for Binge Eating Disorder
This trial tests if tirzepatide (a weekly injection) can help reduce binge eating compared to a placebo or another medication (lisdexamfetamine dimesylate). It may be a good fit for people with moderate or severe binge eating disorder who also have a high body weight.
Baltimore, MarylandAges 18 years+ - NCT06853288Recruiting
How processed foods affect energy from food
This study looks at how eating ultra-processed foods changes how much energy your body takes from food. If you have a BMI between 30 and 40 and are otherwise healthy, you may help scientists learn more about weight and metabolism.
New York, New YorkAges 25 years+ - NCT06845345Enrolling by invitationPhase 4
Can a special diet or pills help liver health?
This study compares two treatments for liver scarring in people with overweight or related health issues. One group follows a special diet with restricted eating times, while the other takes a combination of two medications (naltrexone and bupropion). It aims to see which approach better improves liver fibrosis.
RotterdamAges 18–75 - NCT06824974Recruiting
Time-restricted eating for liver disease or cancer
This study tests whether combining time-restricted eating with healthy eating helps people with metabolic liver disease, cirrhosis, or early-stage liver cancer. If you are overweight and currently fast less than 12 hours at night, this diet approach might improve your health.
La Jolla, CaliforniaAges 18 years+ - NCT06786052RecruitingPhase 2
Study on after-meal energy in adults 50–70
This trial studies how a probiotic supplement affects energy use after meals in adults aged 50–70 who are overweight. You'll take either the probiotic or a placebo for several weeks.
Pierre-Bénite, Auvergne-Rhône-AlpesAges 50–70 - NCT06768216Recruiting
Mediterranean vs. low-fat diet for fatty liver in overweight kids
This trial compares two diets—a Mediterranean-style diet and a low-fat diet—to see which better reduces liver fat in overweight children and teens with fatty liver disease (MASLD). It aims to find a safe, effective eating plan for young people.
New Delhi, National Capital Territory of DelhiAges 8–18 - NCT06768827Recruiting
Obesity mechanisms study for teens
This study looks at how bodies process food to understand obesity in teenagers. It may help find new ways to prevent or treat obesity.
New Haven, ConnecticutAges 15–22 - NCT06755827RecruitingPhase 1/Phase 2
Online weight program for teens 11–14
This study tests a new online program to help teenagers ages 11–14 with overweight or obesity. It uses group meetings and brain scans (MRI) to understand how the program works and if it helps.
Lubbock, TexasAges 11–14 - NCT06759701RecruitingEarly Phase 1
Weight loss drug before prostate cancer surgery pilot study
This study tests if taking tirzepatide (a weight loss medicine) before prostate removal surgery is safe and helpful for overweight men with intermediate-risk prostate cancer. It aims to see if losing weight can improve surgery outcomes.
Houston, TexasAges 18 years+
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Common questions
- Are there clinical trials for overweight?
- Yes. Clin2 currently lists 532 recruiting overweight studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.