Clinical trials
Overweight clinical trials
Below are recruiting overweight clinical trials, each written for real people, not researchers. We’re tracking 515 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07662330Recruiting
Spermidine for weight and cholesterol in overweight adults
This trial tests if a natural supplement called spermidine can help lower cholesterol and body weight in overweight people with high cholesterol. You cannot be on any cholesterol or diabetes medications.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT07419503Enrolling by invitation
Healthy lifestyle program for overweight children
This study evaluates a healthy lifestyle program for children ages 4 to 12 who are overweight. It looks at how well the program works and gathers feedback from children, parents, and program providers.
Rotterdam, South HollandAges 4–12 - NCT07253155Enrolling by invitation
Probiotics for preventing gut symptoms in overweight adults
This study tests whether taking probiotics can help prevent stomach and gut discomfort in people who are overweight or have obesity. You may be eligible if you are at a certain weight and age, eat a balanced diet, and do not have chronic gut issues.
ColeraineAges 18 years+ - NCT07243171RecruitingPhase 1/Phase 2
Oral Ecnoglutide for overweight or obesity
This trial tests an oral medication called Ecnoglutide to help people with overweight or obesity lose weight. It is for Chinese adults who are not diabetic and have a stable weight.
Beijing, Beijing MunicipalityAges 18–65 - NCT07018544Enrolling by invitation
Wegovy safety and effectiveness study in Korea
This study watches how Wegovy (semaglutide) works and its side effects when given by doctors to patients with obesity or overweight in South Korea. It is not testing a new drug, but collecting information from routine care.
Goyang-si, Gyeonggi-doAges 19 years+ - NCT06996431Enrolling by invitation
Weight loss program with mobile health support
This study tests a new way to help adults lose weight using a smartphone app and health coaching. You might qualify if you are overweight, live in Hong Kong, speak Chinese, and can walk without help.
Hong KongAges 18 years+ - NCT07670884RecruitingPhase 3
Study of HRS9531 for weight loss in overweight or obese adults
This trial tests an oral medication, HRS9531, to help overweight or obese adults lose weight. It may be an option if you have been unable to lose enough weight through diet and exercise alone.
Zhengzhou, HenanAges 18–75 - NCT07612527RecruitingPhase 2
Endoscopic Stomach Procedure for Weight Loss
This trial tests a minimally invasive procedure done through the mouth (no surgery) that reshapes the stomach to help with weight loss. It combines two techniques to reduce stomach function and may help people lose weight without traditional bariatric surgery.
CairoAges 18 years+ - NCT07757087RecruitingPhase 1
Study on energy use after weight loss
This study tests a new medicine to see how it affects the body's energy use after losing weight. It compares the medicine to a low-calorie diet or a placebo (a pill with no active ingredient) in adults with obesity.
Aarhus NAges 18 years+ - NCT07724522Recruiting
Prebiotic Fiber for Irregular Periods in Women
This study tests whether taking a prebiotic fiber (inulin) can help women who are in the later years of their reproductive life (before menopause) and have irregular periods. You may be eligible if you are overweight, have irregular cycles, sit a lot, and do not exercise much.
Washington D.C., District of ColumbiaAges 40–55 - NCT07708064Recruiting
Preventing weight regain with a smartphone program
This study tests a smartphone-based program to help people who have lost weight keep it off or lose more. It uses personalized tips and check-ins to prevent giving up if you regain some weight.
Springfield, OregonAges 18–70 - NCT07351110Recruiting
Cervical cancer prevention for women with obesity or diabetes
This trial tests a program to help women with obesity or type 2 diabetes get cervical cancer screenings. It uses text messages or emails to remind and support you in getting screened.
Gainesville, FloridaAges 25 years+ - NCT07275697RecruitingPhase 4
Weight loss drug and heart ablation study for AFib
This trial tests whether a weight loss medication (semaglutide) given before and after a first-time heart ablation procedure for atrial fibrillation can improve outcomes. It is for people who are overweight or obese and have certain related health conditions.
StockholmAges 18 years+ - NCT07654179Recruiting
Metformin for depression with obesity: a genetic study
This trial tests if adding metformin to antidepressants helps people who have both depression and obesity. It also looks at genetic factors that might affect treatment response.
Rawalpindi, Punjab ProvinceAges Any age - NCT07750223Recruiting
Hesperidin for memory and thinking in older adults
This study tests whether a natural supplement called hesperidin (found in citrus fruits) can support brain health in older adults who are overweight or obese. It may help with memory and thinking.
Shanghai, Shanghai MunicipalityAges 55–75 - NCT07748949Recruiting
Low-calorie diet and lifestyle help for type 2 diabetes
This study tests whether a low-calorie diet combined with a personalized lifestyle program can help people with type 2 diabetes reach remission, meaning their blood sugar stays normal without needing diabetes medication. It uses a smartphone app to support the program.
BangkokAges 18–70 - NCT07392190RecruitingPhase 3
Study of eloralintide for people with persistent obesity
This trial tests if adding eloralintide helps people who are still obese or overweight while taking weekly incretin therapy. It aims to support additional weight loss for those who haven't reached their goals.
Birmingham, AlabamaAges 18 years+ - NCT07153471RecruitingPhase 3
A study of an experimental pill for weight loss and knee arthritis
This trial tests an investigational medication (orforglipron) to see if it helps people with knee arthritis lose weight. You may qualify if you have overweight or obesity and have tried dieting before without lasting success.
Phoenix, ArizonaAges 18 years+ - NCT07629544RecruitingPhase 3
Testing DA-302168S for weight loss in overweight and obese adults
This study tests a new medication called DA-302168S to help people lose weight. You may qualify if you're overweight or obese and meet certain health requirements.
BeijingAges 18–75 - NCT07202884RecruitingPhase 3
Orforglipron for Women with Stress Incontinence and Overweight
This study tests an oral medication called orforglipron to see if it helps women with stress urinary incontinence who are also overweight or have obesity. The medicine may reduce leaking episodes and also help with weight loss.
Birmingham, AlabamaAges 18 years+ - NCT06761040Recruiting
Hip and foot strength training for overweight women
This study tests whether adding hip-strengthening exercises to foot-strengthening exercises helps overweight women with flat feet. If you have foot pronation and are in your early 30s, you may be able to join.
Lahore, Punjab ProvinceAges 30–35 - NCT06544954Recruiting
Grape study for heart and gut health in overweight women
This study tests whether eating California grapes can improve gut health and heart health in overweight or obese women who have been through menopause and may have type 2 diabetes or metabolic syndrome. You would need to eat grapes daily and provide blood and stool samples.
Davis, CaliforniaAges 45–70 - NCT05722873Recruiting
Study intermittent fasting and its effects on metabolism
This study looks at how intermittent fasting affects your body's “metabolism” (how you use food and manage blood sugar/fats). It may help researchers understand whether this eating pattern changes metabolic health in people at higher risk for type 2 diabetes.
Pittsburgh, PennsylvaniaAges 21–45 - NCT06745102Recruiting
Hop compounds for immune health in people with extra weight
This trial tests if compounds from hops can help the immune system of people who are overweight and showing early signs of metabolic issues like prediabetes, fatty liver, or mild high blood pressure.
ViennaAges 18–75
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Common questions
- Are there clinical trials for overweight?
- Yes. Clin2 currently lists 515 recruiting overweight studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.