Clinical trials
Overweight clinical trials
Below are recruiting overweight clinical trials, each written for real people, not researchers. We’re tracking 515 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07315282Recruiting
Iron supplements for overweight women: effects on blood sugar
This study tests whether oral iron supplements can improve how the body uses insulin and manages blood sugar in overweight or obese women with low iron stores.
BeirutAges 18–45 - NCT07326111RecruitingPhase 4
Tirzepatide for PCOS and weight in women
This study tests if tirzepatide (a once-weekly injection) can improve periods and metabolic health in women with PCOS who are overweight. If you have PCOS, irregular cycles, and a BMI of 27 or higher, you might qualify.
BochumAges 18–45 - NCT07340125Recruiting
Pistachio snacking and metabolic flexibility study
This study tests whether eating pistachios as a snack can improve how your body uses energy and manages metabolism. It looks at people who are overweight, sleep poorly, and don't exercise much.
Columbia, South CarolinaAges 25–45 - NCT07342855Recruiting
Healthy lifestyle program for children with obesity
This trial looks at how a community healthy lifestyle program helps children with obesity. Your family would join a program that supports healthy eating and physical activity, and researchers will track your child's progress.
Dallas, TexasAges 6–14 - NCT07368777Recruiting
Genetics-based diet counseling vs standard diet for weight loss
This trial compares two types of diet counseling—one based on your genetic makeup and the other standard advice—to see which helps more with weight loss and reducing body fat. It is for adults who are overweight or obese and willing to follow a diet program.
MarousiAges 18–65 - NCT07372157Recruiting
Balance exercises for people with overweight or obesity
This trial tests if neuromuscular balance exercises can help people who are overweight or obese. It aims to improve movement and stability.
Istanbul, IstanbulAges 18–65 - NCT07395687RecruitingPhase 2
Study of UBT251 for people with overweight or obesity
This trial tests different doses of UBT251, a new medicine, to see how well it helps people lose weight. It may be an option if you have overweight or obesity and meet certain age and BMI requirements.
Cypress, CaliforniaAges 18–65 - NCT07395960RecruitingPhase 1/Phase 2
Metformin for older adults with mild memory loss and higher weight
This trial tests if metformin can help older adults (60-75) who are overweight and have mild memory problems. It aims to see if the drug can slow down or improve memory issues.
ShanghaiAges 60–75 - NCT07407348RecruitingPhase 1
Comparing Two Forms of Survodutide in People with Overweight or Obesity
This trial compares how two different forms of the study drug survodutide are absorbed by the body in people with overweight or obesity. It helps doctors understand which version works better.
NottinghamAges 18–65 - NCT07411560RecruitingPhase 1
Weekly injections for stomach side effects in overweight people
This study tests two weekly hormone injections (GIP and amylin) to see how they affect stomach-related side effects in people who are overweight or obese. Researchers want to understand if these hormones can help manage weight or related symptoms.
Harrow, MiddlesexAges 18–64 - NCT07441252RecruitingPhase 2
Study of maridebart cafraglutide for fatty liver with obesity
This trial tests a new medication (maridebart cafraglutide) to see if it can reduce fat in the liver and help with weight loss. It may be an option for adults with excess liver fat and obesity or overweight who haven't been able to lose weight with diet and exercise alone.
Chandler, ArizonaAges 18–99 - NCT07465965RecruitingPhase 1
Weight loss study of semaglutide nasal spray in overweight or obese adults
This study tests a nasal spray containing semaglutide (a GLP-1 receptor agonist) to see if it helps adults who are overweight or obese lose weight. It may be an option if you have a BMI between 27 and 35 and have not used other weight loss medications recently.
Secaucus, New JerseyAges 18–65 - NCT07481747RecruitingPhase 3
Weekly injection for weight loss in adults with obesity
This trial tests a once-weekly injection (tirzepatide) versus a placebo to help people who are obese or overweight with related health conditions lose weight. You may qualify if you have tried to lose weight through diet before, but have not been successful.
Shenzhen, GuangdongAges 18 years+ - NCT07331974Recruiting
A trial of Akkermansia for weight loss in overweight adults
This trial tests a supplement containing Akkermansia bacteria to see if it helps adults who are overweight or obese lose weight. It may be an option if you have not taken weight loss medications recently and are already trying to manage your weight with diet and exercise.
Guangzhou, GuangdongAges 18–60 - NCT07487376RecruitingPhase 1
A single-dose study of IBIO-600 in healthy overweight or obese adults
This trial tests a single dose of an experimental treatment called IBIO-600 to see if it's safe and how it works in overweight or obese adults. It's for people who are generally healthy and have a stable weight, without diabetes.
Bayswater, VictoriaAges 18–65 - NCT07497555Recruiting
Pecan nut oil for inflammation in overweight adults
This study tests if taking pecan nut oil every day can reduce inflammation in adults who are overweight. It may help improve health and lower the risk of future disease.
Monterrey, Nuevo LeónAges 18–55 - NCT07501377Recruiting
Diet and brain health study for women in menopause with overweight
This trial tests whether a diet rich in fiber and plant compounds (polyphenols) can reduce brain inflammation in perimenopausal women who are overweight. If you're in early menopause and have some inflammation, this study may show how diet affects your brain health.
Leipzig, SaxonyAges 35–60 - NCT07528027RecruitingPhase 3
Testing HRS-7535 for High Blood Pressure and Extra Weight
This study tests whether a new medicine called HRS-7535 can help lower blood pressure in people who are overweight or have obesity. You would take it alongside your current blood pressure medications (or as a new treatment) to see if it works better at controlling your blood pressure.
Beijing, Beijing MunicipalityAges 18–70 - NCT07550816RecruitingPhase 1
Safety study of ZT002 injection in overweight adults
This study tests how a new diabetes medicine called ZT002 works in the body and whether it interacts safely with other common medications. Researchers will monitor healthy volunteers who are overweight to understand the medicine's safety and effectiveness.
Chengdu, SichuanAges 18–45 - NCT07557953RecruitingPhase 1
How cagrilintide affects hunger and eating in overweight adults
This early-stage study tests a new medication called cagrilintide to see how it influences appetite and food intake in adults with overweight or obesity. Researchers want to understand if this drug could help people feel fuller and eat less.
BerlinAges 18–64 - NCT07582718Recruiting
High-Intensity Interval Training for Fitness in Adults
This study tests whether intense, short bursts of exercise can improve fitness in adults who are overweight. You'll do whole-body workouts designed to boost cardiovascular health and physical performance.
BrusselsAges 18–55 - NCT07589608RecruitingPhase 2
Weight Loss Study With Two New Injectable Medications
This study tests two new injectable drugs (macupatide and eloralintide) alone or together to help adults with obesity or excess weight lose weight. The goal is to see if these medications are safe and effective for weight management.
Chandler, ArizonaAges 18–75 - NCT07597018RecruitingPhase 1
Comparing Blood Levels of Cagrilintide Versions in Adults With Overweight
This early-stage study tests different formulations of cagrilintide, a new medication, to see how the body absorbs and processes each version. Cagrilintide may help with weight management. Researchers will measure blood levels after you receive multiple doses.
BerlinAges 18–64 - NCT07654439Recruiting
Mixed reality tests for overweight and obese adults
This trial tests if mixed reality (combining real and virtual worlds) performance tests are valid and reliable for overweight and obese adults. You may be able to help researchers improve these tests if you are overweight or obese.
Konya, SelcukluAges 18–65
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Common questions
- Are there clinical trials for overweight?
- Yes. Clin2 currently lists 515 recruiting overweight studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.