Clinical trials
Pain and Anxiety clinical trials
Below are recruiting pain and anxiety clinical trials, each written for real people, not researchers. We’re tracking 145 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07261839Enrolling by invitation
Meditation's effect on anxiety and pain during endoscopy
This study tests whether a guided meditation can help you feel less anxious and more comfortable during an endoscopy procedure. It may be a good fit if you are having an endoscopy for the first time and want a non-drug way to relax.
Gaziantep, ŞehitkamilAges 18 years+ - NCT07469345Enrolling by invitation
Teeth Grinding and Pelvic Pain in Young Men
This study looks at how teeth grinding (bruxism) is linked to pelvic pain, erectile function, and anxiety in young adult men. It aims to understand if these issues are connected, which could help develop better treatments.
KonyaAges 18–30 - NCT06928740Recruiting
Music app vs. gas for anxiety during back injection
This trial tests whether listening to a digital music app can reduce anxiety as well as a standard gas (laughing gas) does in people getting a CT-guided back injection for low back pain.
NîmesAges 18 years+ - NCT07743736Recruiting
Aromatherapy and massage after cesarean delivery
This trial tests whether aromatherapy and massage help new mothers recover after a cesarean birth. It may reduce pain and improve well-being after delivery.
Uşak, UşakAges 18–40 - NCT07502157Recruiting
Massage for pain and anxiety during first cancer infusion
This study tests whether massage therapy can help reduce pain and anxiety in people with gynecologic cancer who are getting their first infusion treatment. You may be eligible if you are about to receive your first infusion and haven't had any in the past 2 years.
Lexington, KentuckyAges 18–85 - NCT07738718Recruiting
Virtual reality for dental fillings with deep cavities
This study tests if using virtual reality during dental filling procedures can reduce pain and anxiety. It is for adults with moderate tooth decay on both sides of the mouth who have mild, reversible pulpitis.
Ar Rass, Al-Qassim RegionAges 18 years+ - NCT04163809Recruiting
Using virtual reality during regional anesthesia
This trial studies whether virtual reality (VR) can help patients during regional anesthesia, a type of pain-control used during surgery. If you’re having an elective procedure with regional anesthesia, this may test how VR affects comfort, anxiety, or experience during care.
Los Angeles, CaliforniaAges 18–64 - NCT05883540RecruitingPhase 2
LSD therapy in palliative care for comfort and well-being
This Phase 2 study tests how LSD may affect comfort and quality of life for people with advanced or end-stage life-limiting illness. It also checks whether the medicine is safe and can be given in a controlled way in palliative care settings.
BaselAges 22 years+ - NCT05973201Recruiting
Virtual reality to ease anxiety and pain during lung scope
This study tests whether virtual reality (VR) can reduce anxiety and pain and shorten the time during a non-emergency breathing tube/airway procedure in the ICU. If you’re eligible, you may use VR during your first bronchoscopy during this hospital stay.
Aix-en-ProvenceAges 18 years+ - NCT06297200Recruiting
Ultrasound treatment for complex back pain patients
This study tests a new, non-invasive ultrasound treatment for people with long-term back pain who also have opioid use disorder and anxiety. It aims to see if this gentle brain stimulation can reduce pain and improve quality of life.
Roanoke, VirginiaAges 18–65 - NCT06419842Recruiting
Hypnosis for lumbar infusion test comfort
This trial tests whether hypnosis can help make a lumbar infusion test (a procedure to check for normal pressure hydrocephalus) more comfortable. It's for adults 65 and older who are already scheduled for this test.
Amiens, PicardieAges 65 years+ - NCT06453109Recruiting
Focused ultrasound for chronic back pain with opioid use
This study tests whether focused ultrasound (a non-invasive treatment using sound waves) can help people with chronic back pain who also have opioid use disorder and anxiety. It aims to find a better way to manage pain without relying on opioids.
Washington D.C., District of ColumbiaAges 18–75 - NCT04214561Enrolling by invitation
Studies how sleep measures relate to teeth grinding
This study looks at sleep testing results to understand what relates to sleep bruxism, which is teeth grinding or clenching during sleep. It may help researchers better understand the causes and patterns behind this condition.
WroclawAges 18–70 - NCT06575322Recruiting
Neoadjuvant therapy for head and neck cancer: effects on pain and mood
This trial tests whether adding immunotherapy to chemotherapy before surgery can help reduce pain, anxiety, and depression in people with head and neck cancer. The goal is to see if this approach improves quality of life during treatment.
Guanzhou, GuangdongAges 18–80 - NCT06675877Recruiting
Virtual reality for kids with kidney disease on dialysis
This study tests whether virtual reality (VR) can help reduce anxiety and depression in children with end-stage kidney disease who are on hemodialysis through an arteriovenous fistula. It may offer a fun, drug-free way to feel better during treatment.
TantaAges 8–18 - NCT06708585Recruiting
Relaxation exercises for first-time mothers before c-section
This study tests whether providing information and teaching progressive muscle relaxation can help first-time mothers feel more relaxed and prepared before a planned cesarean section.
NiğdeAges 18–35 - NCT06729294Recruiting
Does music help during knee replacement surgery?
This study tests if listening to music during knee replacement surgery under spinal anesthesia can lower anxiety, pain, and stress hormone levels. It may help make the experience calmer for patients.
Kocasinan, KayseriAges 18 years+ - NCT06759337Recruiting
Stress ball or hand holding during IUI for pain and anxiety
This trial tests if using a stress ball or having your hand held during intrauterine insemination (IUI) can reduce pain, anxiety, and discomfort. It compares these two simple comfort techniques to standard care.
Kayseri, MelikgaziAges 18–50 - NCT06969105Recruiting
Music for comfort during labor and delivery
This study tests whether listening to music during labor can help reduce pain and anxiety. Researchers will compare outcomes for laboring women who listen to music versus those who do not.
Boston, MassachusettsAges 18 years+ - NCT06992895Recruiting
Hologram for pain and fear during burn dressing changes in children
This trial tests whether watching a hologram during burn dressing changes can reduce pain, anxiety, and fear in children. It may help make the experience less stressful for kids aged 3 to 12 with small, second-degree burns.
Erzurum, YakutiyeAges 3–12 - NCT06996340Recruiting
White noise during IVF treatment for women with infertility
This study tests whether listening to white noise can help reduce stress in women undergoing in vitro fertilization (IVF) for the first time. It may help you feel more relaxed during treatment.
Samsun, AtakumAges 18–35 - NCT07073027Recruiting
How digital media affects kids' healthcare experiences
This study looks at how using digital media (like videos or apps) before or during a hospital procedure affects kids' experiences. If you have a smartphone and a procedure coming up, you may be able to join.
Vancouver, British ColumbiaAges 5–23 - NCT07114003Recruiting
Virtual reality for pain and anxiety during wound dressing changes
This study tests whether using virtual reality during wound dressing changes can help reduce pain and anxiety and improve satisfaction for people with pressure sores (bedsores).
Mersin, TarsusAges 18 years+ - NCT07265960Recruiting
Virtual reality and stress ball for kidney stone procedure
This study tests if using a virtual reality headset or squeezing a stress ball can help reduce fear, pain, and anxiety during a procedure called ureteroscopy (a scope to treat kidney stones). It aims to make the experience more comfortable for you.
Mersin, TarsusAges 18 years+
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Common questions
- Are there clinical trials for pain and anxiety?
- Yes. Clin2 currently lists 145 recruiting pain and anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain and anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain and anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.