Clinical trials
Pain and Anxiety clinical trials
Below are recruiting pain and anxiety clinical trials, each written for real people, not researchers. We’re tracking 144 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07060170Recruiting
Can VR or AR glasses help kids feel less pain at the dentist?
This study tests if wearing fun glasses that show virtual or augmented reality can help children feel less pain and worry when getting a numbing shot for a cavity. It compares two types of high-tech glasses to see which works better.
Cairo, EgyptAges 5–8 - NCT06182436Recruiting
Virtual reality for pain during eczema injection
This trial tests whether playing a virtual reality game during a dupilumab injection (for eczema) can help reduce pain and anxiety. It's for kids and teens aged 6 to 17 who are already taking or about to start this medicine.
Montreal, QuebecAges 6–17 - NCT06347679Recruiting
Can aromatherapy ease anxiety and pain during dental work?
This study tests whether smelling certain essential oils (aromatherapy) can help reduce anxiety and pain during dental treatments. If you are an adult having a dental procedure, this may be a way to feel more comfortable without medication.
Chengdu, SichuanAges 18–40 - NCT07261839Enrolling by invitation
Meditation's effect on anxiety and pain during endoscopy
This study tests whether a guided meditation can help you feel less anxious and more comfortable during an endoscopy procedure. It may be a good fit if you are having an endoscopy for the first time and want a non-drug way to relax.
Gaziantep, ŞehitkamilAges 18 years+ - NCT07469345Enrolling by invitation
Teeth Grinding and Pelvic Pain in Young Men
This study looks at how teeth grinding (bruxism) is linked to pelvic pain, erectile function, and anxiety in young adult men. It aims to understand if these issues are connected, which could help develop better treatments.
KonyaAges 18–30 - NCT06928740Recruiting
Music app vs. gas for anxiety during back injection
This trial tests whether listening to a digital music app can reduce anxiety as well as a standard gas (laughing gas) does in people getting a CT-guided back injection for low back pain.
NîmesAges 18 years+ - NCT07872215Recruiting
AI-assisted teaching before stitches for minor cuts
This study tests whether using artificial intelligence to explain stitches before the procedure helps patients feel more informed and at ease. It is for adults with minor cuts that can be closed with stitches in the emergency room.
AnkaraAges 18 years+ - NCT07872670Recruiting
Virtual reality to help recovery after hip or knee replacement
This study uses virtual reality (a computer-generated 3D environment you wear a headset for) alongside your usual care to help with recovery after hip or knee replacement surgery. It may help reduce pain or improve how well you move after surgery.
Inverness, HighlandsAges 18 years+ - NCT07853300Enrolling by invitation
Virtual reality for comfort during colonoscopy
This study tests whether using virtual reality (a computer-generated 3D environment you can see and hear) during a colonoscopy can reduce pain, anxiety, and embarrassment. If it works, it could make the procedure more comfortable for people who have it without sedation.
Kocaeli, İzmitAges 18–65 - NCT06575322Recruiting
Neoadjuvant therapy for head and neck cancer: effects on pain and mood
This trial tests whether adding immunotherapy to chemotherapy before surgery can help reduce pain, anxiety, and depression in people with head and neck cancer. The goal is to see if this approach improves quality of life during treatment.
Guanzhou, GuangdongAges 18–80 - NCT07679295Enrolling by invitation
Port needle change: pain, anxiety, and satisfaction
This trial tests if using a stress ball during port needle changes can help reduce pain and anxiety in cancer patients. It aims to improve comfort and patient satisfaction.
SanliurfaAges 18 years+ - NCT06675877Recruiting
Virtual reality for kids with kidney disease on dialysis
This study tests whether virtual reality (VR) can help reduce anxiety and depression in children with end-stage kidney disease who are on hemodialysis through an arteriovenous fistula. It may offer a fun, drug-free way to feel better during treatment.
TantaAges 8–18 - NCT07659015Enrolling by invitation
Using a hand exercise tool during IV placement
This study tests if using a simple hand-extension rubber band during IV placement can help reduce pain or improve the procedure. It may be an option for right-handed adults getting an IV in specific arm veins.
Konya, MeramAges 18–65 - NCT06453109Recruiting
Focused ultrasound for chronic back pain with opioid use
This study tests whether focused ultrasound (a non-invasive treatment using sound waves) can help people with chronic back pain who also have opioid use disorder and anxiety. It aims to find a better way to manage pain without relying on opioids.
Washington D.C., District of ColumbiaAges 18–75 - NCT07533669Recruiting
Sensory room visit before kidney transplant surgery
This study tests whether spending time in a calming sensory room before kidney transplant surgery helps reduce pain, anxiety, and sleep problems. You would visit a specially designed room with soothing sights, sounds, and textures before your operation.
SakaryaAges 18 years+ - NCT06759337Recruiting
Stress ball or hand holding during IUI for pain and anxiety
This trial tests if using a stress ball or having your hand held during intrauterine insemination (IUI) can reduce pain, anxiety, and discomfort. It compares these two simple comfort techniques to standard care.
Kayseri, MelikgaziAges 18–50 - NCT07502157Recruiting
Massage for pain and anxiety during first cancer infusion
This study tests whether massage therapy can help reduce pain and anxiety in people with gynecologic cancer who are getting their first infusion treatment. You may be eligible if you are about to receive your first infusion and haven't had any in the past 2 years.
Lexington, KentuckyAges 18–85 - NCT07449273Recruiting
Breathing exercises after breast surgery
This study tests breathing exercises to help you recover after breast surgery. It may improve your breathing and comfort during recovery.
Istanbul, IstanbulAges 18 years+ - NCT07424209Recruiting
Hypnotic communication during heart catheterization study
This study tests whether talking in a special relaxed way (hypnotic communication) during a heart procedure can help you feel calmer and more comfortable. You may be able to join if you are at least 18, can understand Italian, and are already scheduled for a coronary angiogram.
Ponderano, ItalyAges 18 years+ - NCT07173231Recruiting
Using virtual reality for diagnostic hysteroscopy
This trial tests if using virtual reality (VR) can make diagnostic hysteroscopy, a procedure to look inside the uterus, more comfortable. It may help patients who are anxious about the procedure.
Montreal, QuebecAges 18 years+ - NCT07073027Recruiting
How digital media affects kids' healthcare experiences
This study looks at how using digital media (like videos or apps) before or during a hospital procedure affects kids' experiences. If you have a smartphone and a procedure coming up, you may be able to join.
Vancouver, British ColumbiaAges 5–23 - NCT06996340Recruiting
White noise during IVF treatment for women with infertility
This study tests whether listening to white noise can help reduce stress in women undergoing in vitro fertilization (IVF) for the first time. It may help you feel more relaxed during treatment.
Samsun, AtakumAges 18–35 - NCT06992895Recruiting
Hologram for pain and fear during burn dressing changes in children
This trial tests whether watching a hologram during burn dressing changes can reduce pain, anxiety, and fear in children. It may help make the experience less stressful for kids aged 3 to 12 with small, second-degree burns.
Erzurum, YakutiyeAges 3–12 - NCT06969105Recruiting
Music for comfort during labor and delivery
This study tests whether listening to music during labor can help reduce pain and anxiety. Researchers will compare outcomes for laboring women who listen to music versus those who do not.
Boston, MassachusettsAges 18 years+
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Common questions
- Are there clinical trials for pain and anxiety?
- Yes. Clin2 currently lists 144 recruiting pain and anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain and anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain and anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.