Clinical trials
Pain Syndrome clinical trials
Below are recruiting pain syndrome clinical trials, each written for real people, not researchers. We’re tracking 265 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04704297RecruitingPhase 4
Trigger point shots for low back muscle pain
This trial tests whether injecting sore “trigger points” in low back muscles helps improve chronic low back pain. It compares treatments in people with specific low back muscle pain patterns and excludes several other causes of pain.
Tacoma, WashingtonAges 18 years+ - NCT07839689Recruiting
Aerobic exercise and massage for painful bladder syndrome
This study tests whether adding aerobic exercise and connective tissue massage to your usual care can help reduce bladder pain and discomfort. It aims to improve symptoms in women with painful bladder syndrome.
Ankara, AnkaraAges 18 years+ - NCT07785362Enrolling by invitation
Brain stimulation for teens with fibromyalgia or chronic pain
This study tests a non-invasive brain stimulation technique to see if it can reduce pain in teenagers and young adults with fibromyalgia or other long-lasting muscle and bone pain that hasn't responded to usual treatments. It aims to help calm overactive pain signals in the brain.
Genova, GEAges 10–21 - NCT07671482Recruiting
Kinesio vs McConnell taping for knee pain relief
This study compares two types of taping (Kinesio and McConnell) to see which works better for people with pain behind the kneecap (patellofemoral pain syndrome). You may help researchers learn how to best relieve knee pain during daily activities.
Beirut, BeirutAges 18–50 - NCT07568015Recruiting
Nerve-targeted treatment for lateral hip pain
This study tests an experimental treatment that targets nerves around the hip to relieve pain on the outside of the hip. It may help people who have tried other treatments without enough relief.
Sun City, ArizonaAges 22–80 - NCT07562425Recruiting
Knee Strengthening Exercises for Patellofemoral Pain
This study compares three types of thigh muscle exercises to help reduce knee pain in people with patellofemoral pain syndrome (pain around the kneecap). Researchers want to see which exercise style—holding steady, moving through motion, or lowering slowly—works best for your pain.
Elâzığ, MErkezAges 18–50 - NCT07494162Recruiting
Acupuncture for chronic low back pain with muscle knots
This trial tests if acupuncture can help chronic low back pain by looking at changes in muscle metabolism and blood flow. It compares real acupuncture with a sham (fake) procedure to see if there is a true benefit.
Sacramento, CaliforniaAges 18 years+ - NCT07473635Recruiting
Botox injections for nerve pain in CRPS — an early safety study
This study tests whether a specially targeted injection of botulinum toxin (like Botox) around nerves can help reduce pain from CRPS. It aims to see if the treatment is safe and doable for people with long-lasting CRPS.
Glostrup, Region SjællandAges 18 years+ - NCT06769373Recruiting
Whirlpool and contrast bath for CRPS after wrist fracture
This study tests whether warm water whirlpool baths or alternating hot and cold water baths (contrast bath) can help reduce pain and improve function in people with Complex Regional Pain Syndrome (CRPS) after a wrist fracture that was treated without surgery.
Afyonkarahisar, AfyonkarahisarAges 18–70 - NCT07446712Recruiting
Oxygen Therapy for Complex Regional Pain Syndrome
This trial tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can help reduce pain from Complex Regional Pain Syndrome (CRPS) Type I. If you have this condition, the therapy may improve your symptoms.
Ostrava, Moravian-Silesian RegionAges 18 years+ - NCT07415967Recruiting
Dual-task exercise for rotator cuff shoulder pain
This study tests an exercise program that combines shoulder movements with mental tasks (like counting or naming things) to improve pain and function. It is for people with ongoing shoulder pain from common rotator cuff problems.
IstanbulAges 18–65 - NCT06835868Recruiting
Registry for nerve stimulation treatments for chronic pain in Belgium
This trial creates a registry for people with chronic pain who are getting special nerve-modulating treatments in Belgium. It focuses on two specific chronic pain conditions: Persistent Spinal Pain Syndrome Type 2 (pain after spine surgery) and Complex Regional Pain Syndrome (a type of nerve pain).
Edegem, AntwerpAges Any age - NCT07324343Recruiting
Education for shoulder pain: which patients benefit most?
This study tests whether patients with different types of shoulder pain respond better to learning about their condition through education alone. You will receive information and advice to help you manage your pain without injections or surgery.
IstanbulAges 18–65 - NCT07057128Recruiting
Do nerve issues occur in shoulder pain syndrome?
This study looks at whether nerve-related symptoms are common in people with subacromial pain syndrome (a type of shoulder pain). You may qualify if you have shoulder pain that has lasted at least 3 months, with moderate to severe pain in the past week, and if you haven't had shoulder surgery or certain other shoulder problems.
Izmir, İzmirAges 19 years+ - NCT06929598Recruiting
Shiatsu for chronic pain in children and teens
This study tests whether Shiatsu—a gentle, hands-on therapy—can help reduce chronic, non-inflammatory pain in children and adolescents. If you or your child have had long-term pain without inflammation and are already being seen at a specific pain clinic in Tel Aviv, this trial might be a good fit.
Tel Aviv, Tel AvivAges 10–18 - NCT06825390Recruiting
Ear stimulation and brain imaging for chronic low back pain
This study tests if a non-invasive ear stimulation technique can change brain activity linked to chronic low back pain. You would have a brain scan before and after the treatment to see how your brain responds.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06798493Enrolling by invitation
CRPS and chronic pain measurement study
This study is testing a new way to measure CRPS symptoms and other chronic pain in one arm or leg. It aims to help doctors better understand and treat your condition.
New York, New YorkAges 18 years+ - NCT06778070Recruiting
Pelvic pain study testing yoga therapy for relief
This trial tests whether yoga therapy can help reduce chronic pelvic pain in women and non-binary individuals over 6 months. You'll join online yoga classes and see if they improve your pain and daily life.
San Francisco, CaliforniaAges 18 years+ - NCT05754190Recruiting
Smartphone study of mood and symptoms in people with pain
This study uses a smartphone app to track daily pain and mood changes over about 4 months. It’s meant to learn patterns that could help better understand how mood and pain affect each other.
Providence, Rhode IslandAges 18 years+ - NCT06306157Enrolling by invitationPhase 4
Low dose naltrexone for complex regional pain syndrome
This trial tests whether a low dose of naltrexone, a medication that may help calm overactive immune and pain signals, can reduce pain and improve daily life in people with complex regional pain syndrome (CRPS), a chronic condition that often causes severe pain and swelling.
New York, New YorkAges 18–85 - NCT06299683Recruiting
Pain type and bladder pain syndrome treatment study
This study is testing if the type of pain you feel can help predict which treatments work best for interstitial cystitis (a condition that causes bladder pain and pressure). It may help match you with more effective care.
Franklin, TennesseeAges 18 years+ - NCT06168058Recruiting
Pelvic vein embolization for chronic pelvic pain
This trial tests if blocking enlarged veins in the pelvis (called embolization) can reduce long-term pelvic pain that hasn't improved with other treatments. It may help women whose pain is worse when standing or walking and better when lying down.
New Hyde Park, New YorkAges 18–75 - NCT06096597RecruitingPhase 2/Phase 3
Amniotic Membrane Therapy for Bladder Pain
This trial tests a treatment made from amniotic membrane (a natural tissue) to help reduce pain and discomfort in people with Interstitial Cystitis (also called Painful Bladder Syndrome). It is for women who have tried at least one other treatment without success.
Clevleand, OhioAges 18 years+ - NCT05851326Recruiting
Ultrasound and gentle stimulation for stubborn muscle pain
This trial tests whether low-energy ultrasound and electrical/magnetic stimulation can reduce long-lasting myofascial pain in the low back, neck, or tension-type headaches. It may help if your pain has lasted at least 3 months and is still noticeable despite your current treatment plan.
GrazAges 18–99
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Common questions
- Are there clinical trials for pain syndrome?
- Yes. Clin2 currently lists 265 recruiting pain syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.