Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,262 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06708585Recruiting
Relaxation exercises for first-time mothers before c-section
This study tests whether providing information and teaching progressive muscle relaxation can help first-time mothers feel more relaxed and prepared before a planned cesarean section.
NiğdeAges 18–35 - NCT06710002Recruiting
Home program for sexual pain in menopause
This trial tests a home-based therapy program (telerehabilitation) designed to reduce pain during sex and improve sexual function in menopausal women. The program involves exercises and guidance you can do from home without needing to visit a clinic.
Barcelona, SpainAges 45–65 - NCT06718296Recruiting
Photographic Shoulder Pain Scale Study
This study is creating a new way to measure shoulder pain using pictures. It is for people who have had shoulder pain for more than 3 months, whether from an injury or other causes.
IstanbulAges 18–64 - NCT06718413RecruitingPhase 2
Study on shoulder pain after stroke
This study tests a treatment for shoulder stiffness and pain caused by muscle tightness after a stroke. It focuses on people who still have some limited shoulder movement and may help improve range of motion and comfort.
Baltimore, MarylandAges 18 years+ - NCT06718569Recruiting
Pain in Inflammatory Joint Diseases
This study looks at pain in people with inflammatory joint diseases. It aims to understand how pain changes when you start or switch to a newer type of arthritis medication.
OsloAges 18 years+ - NCT06719232Recruiting
Testing a new way to give bladder treatment without a catheter
This study tests a catheter-free method for delivering medication directly into the bladder. It may help patients with bladder pain, recurrent infections, bladder cancer, or cystitis after radiation or chemotherapy.
BudapestAges 18–80 - NCT06721819RecruitingPhase 3
Sleep and brain training before heart surgery to prevent delirium
This study tests whether a combination of sleep therapy, brain games, and light exercise before heart surgery can help prevent confusion or disorientation (delirium) after the operation. Participants will be asked to use a tablet and fitness tracker daily for about an hour before their surgery.
Boston, MassachusettsAges 60 years+ - NCT06723353Recruiting
Combined therapy for belly separation in new mothers
This trial tests if a gentle hands-on treatment (visceral manipulation) plus special tape (kinesio taping) can help close the gap in your belly muscles, reduce pain, stop bladder leaks, and improve your pelvic floor strength and overall well-being after childbirth.
Karachi, SindhAges 35–45 - NCT06725862Recruiting
Pain relief methods for undescended testis surgery in children
This study compares two different numbing injections (caudal block vs retrolaminar block) given before surgery to see which one provides better pain control for children aged 1-7 undergoing undescended testis surgery.
IstanbulAges 1–7 - NCT06729294Recruiting
Does music help during knee replacement surgery?
This study tests if listening to music during knee replacement surgery under spinal anesthesia can lower anxiety, pain, and stress hormone levels. It may help make the experience calmer for patients.
Kocasinan, KayseriAges 18 years+ - NCT06731647RecruitingPhase 2
Anti-inflammatory drugs for pleurodesis in pneumothorax
This trial tests whether using non-steroidal anti-inflammatory drugs (NSAIDs) during pleurodesis (a procedure to seal the lung lining) helps people with a collapsed lung (pneumothorax). It aims to see if these drugs can improve outcomes.
AmiensAges 18 years+ - NCT06731985Recruiting
Shorter sling tape follow-up study
This study looks at how well and how safely a shorter type of sling tape (used to treat stress urinary incontinence) works over time. It may help women who had this specific surgery between 2009 and 2020 understand their long-term results.
LorenskogAges 25–90 - NCT06731998Recruiting
Improving pain control after cancer surgery
This study compares different methods of managing pain after minimally invasive surgery for abdominal cancers. It aims to find which approach works best to reduce pain and improve recovery.
Pittsburgh, PennsylvaniaAges 18–89 - NCT06736483RecruitingPhase 2
Dexmedetomidine for children’s groin surgery recovery
This trial tests whether adding a sedative called dexmedetomidine to a numbing shot (nerve block) helps children aged 1–7 recover better after groin surgery. The goal is to improve comfort and reduce side effects.
Montpellier, FranceAges 1–7 - NCT06736756Recruiting
Stretching hip muscle to help with knee pain
This trial tests if stretching the tensor fascia lata muscle (near your hip) changes how the muscle on the inside of your kneecap works. It is for people who have front knee pain without a specific injury, especially when doing things like running, squatting, or climbing stairs.
CairoAges 18–30 - NCT06736795Recruiting
Online support for Achilles tendon loading exercises
This study tests whether extra support from a clinician during a progressive exercise program helps people with Achilles tendon pain improve faster. You'll do exercises that gradually increase the load on your tendon, with guidance from a physical therapist via video visits.
Iowa City, IowaAges 18–60 - NCT06737900Recruiting
Jandas vs PNF for pain and mobility in lower back pain
This study compares two physical therapy methods—Jandas Approach and PNF (Proprioceptive Neuromuscular Facilitation)—to see which works better for reducing lower back pain, improving movement, and making daily activities easier. It is for adults with ongoing back pain and specific muscle tightness or weakness.
Lahore, Punjab ProvinceAges 25–40 - NCT06740214RecruitingPhase 3
Different doses of liposomal bupivacaine for knee replacement pain
This trial tests different doses of a long-acting painkiller (liposomal bupivacaine) injected into a nerve block in the thigh to see which dose works best for pain after knee replacement surgery. It may help you have better pain control and recover faster.
Hong Kong, Hong KongAges 18–80 - NCT06740903RecruitingPhase 2/Phase 3
Comparing two drugs for pain control in gallbladder surgery
This study compares two medications, dexmedetomidine and lignocaine, to see which works better for pain management during and after laparoscopic gallbladder removal. It may help improve comfort and recovery for people having this surgery.
Sahiwal, Punjab ProvinceAges 20–70 - NCT06741059Recruiting
TENS for period pain relief
This study tests if TENS, a gentle electrical stimulation device, can reduce period pain and related symptoms. If you have painful periods and are not using other treatments, this might be an option for you.
OsmaniyeAges 18 years+ - NCT06741696Recruiting
Saline rinsing after wisdom tooth removal
This trial tests whether using saline (salt water) at different temperatures after wisdom tooth surgery helps with healing and pain. It could help you recover more comfortably.
Rawalpindi, Punjab ProvinceAges Up to 59 years - NCT06744257Recruiting
Online education for kneecap pain while waiting for physio
This trial tests whether an online education program is helpful for people with kneecap pain who are waiting for in-person physiotherapy. It aims to see if this approach is practical and beneficial.
ColchesterAges 16–44 - NCT06745388RecruitingPhase 4
Magnesium for cramping during hysteroscopy or D&C
This study tests whether magnesium can reduce cramping during a hysteroscopy or D&C. If you are having one of these procedures and are not on certain medications, you may qualify.
Royal Oak, MichiganAges 18 years+ - NCT06746922Recruiting
Brain stimulation for fibromyalgia pain
This study tests a type of non-invasive brain stimulation called Intermittent Theta Burst Stimulation (iTBS) to see if it can help reduce pain and improve daily function in people with fibromyalgia. It may offer a new option for managing your pain without medication changes.
Izmir, KarabaglarAges 18–65
Hear when a new Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,262 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.