Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,138 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07101068Recruiting
Comparing two ways to give dental numbing for kids
This study tests a new dental injector against a traditional syringe to see which one causes less pain and anxiety for children getting numbed for their first cavity treatment.
Cairo, Cairo GovernorateAges 6–8 - NCT07100613RecruitingPhase 2
Mouth film for treating oral lichen planus
This trial tests a new sticky mouth film that slowly releases medicine to treat painful sores from oral lichen planus. It may help people who have not been treated before for this condition.
Palermo, ItalyAges 18 years+ - NCT07102121Enrolling by invitation
Comparing tooth sensitivity after cementing crowns with two dental materials
This study tests whether one type of dental cement causes less tooth sensitivity than another after placing a crown. The results could help your dentist choose the material that feels better for you.
Mingora, Khyber PakhtunkhwaAges 15–60 - NCT07101887Recruiting
Comparing two surgeries for thumb arthritis pain and function
This trial tests if a thumb joint replacement works better than the standard surgery for reducing pain and improving hand use in people with thumb arthritis (grades I to III).
BarcelonaAges Any age - NCT07099560Recruiting
Comparing two numbing blocks for hypospadias repair in children
This study compares two ways to numb the lower belly and groin area for children having hypospadias repair. It tests if a newer injection method (sacral erector spinae block) works as well as the standard method (caudal block) to control pain during and after surgery.
Tanta, El-Gharbia GovenorateAges 1–5 - NCT06205875Recruiting
High vs. low dose pain block after minimally invasive heart valve surgery
This trial compares two doses of a numbing medicine injected into the chest wall to control pain after heart valve surgery. If you qualify, you will receive either a higher or lower dose of the pain block to see which provides better pain relief and recovery.
Hasselt, LimburgAges 18 years+ - NCT06755671Recruiting
Danning tablets for digestive symptom relief
This study looks at how well Danning tablets work for people with upset stomach, bloating, heartburn, or constipation. It follows patients who are already taking the tablets as part of their regular care.
Hangzhou, ZhejiangAges 18–75 - NCT06972199Recruiting
Foot massage or warm water bath for pain after colon cancer surgery
This trial tests whether a foot massage or a warm water foot bath can help reduce pain and improve recovery after laparoscopic surgery for colon cancer.
Istanbul, IstanbulAges 18 years+ - NCT06970431Recruiting
Anxiety and pain relief during C-section
This trial tests a way to reduce anxiety and pain before and during a C-section. It may help pregnant women feel calmer and more comfortable.
Wuhan, HubeiAges 18–40 - NCT07092605Enrolling by invitationEarly Phase 1
Microdosed semaglutide for longer, healthier life
This trial tests whether a very low ('micro') dose of semaglutide can improve health, quality of life, and how long you live well. It's for people who are interested in the drug's general health benefits but not specifically for weight loss.
Ann Arbor, MichiganAges 18–65 - NCT06859164RecruitingPhase 2
Knee artery treatment for chronic osteoarthritis pain
This trial tests a procedure called genicular artery embolization to reduce pain in people with knee osteoarthritis that hasn't improved with other treatments. The goal is to see if blocking certain blood vessels can relieve pain and help you avoid or delay knee replacement surgery.
Chicago, IllinoisAges 40–80 - NCT07095569Recruiting
Shoulder nerve block for pain after breast cancer radiation
This trial tests a procedure to block shoulder nerves to relieve pain caused by radiation therapy after mastectomy. It may help if you have ongoing shoulder pain after breast cancer treatment.
Cairo, Cairo GovernorateAges 18–65 - NCT07094997Recruiting
Massage therapy for healthcare workers with low back pain
This study tests if massage therapy can help healthcare workers with ongoing low back pain. If you qualify, you would receive several massage sessions to see if they reduce your pain and improve your well-being.
Wroclaw, Lower Silesian VoivodeshipAges 30–65 - NCT07090928RecruitingPhase 4
Numbing medicine for less pain after knee scope surgery
This study tests whether giving bupivacaine (a numbing medicine) around the time of knee arthroscopy can reduce pain at the surgery sites and help you move your knee better after the operation.
Peshawar, KPKAges 18–70 - NCT07092566RecruitingPhase 3
Pain relief after robotic kidney surgery: R.E.C.K. vs Exparel
This trial tests two different pain-relief medicines (R.E.C.K. and Exparel) given during robotic kidney surgery. It aims to find which works better to control pain after the operation.
Charlotte, North CarolinaAges 18 years+ - NCT07093437Recruiting
Comparing ways to secure urinary catheters in ICU patients
This study compares two methods of securing a urinary catheter to the thigh to see which works better. It's for patients in the intensive care unit (ICU) who need a catheter for more than 48 hours.
BarcelonaAges 18–99 - NCT07090668Recruiting
Ear stimulation for pain in sickle cell disease
This trial tests a safe, non-drug device that gently stimulates the ear to help reduce pain in children with sickle cell disease who are in the hospital for a pain crisis. It may offer a new way to manage pain without extra medication.
Atlanta, GeorgiaAges 7–18 - NCT07095556Recruiting
Laser therapy to help gums heal after tooth extraction
This trial tests whether a special laser treatment can help your gums heal better after a tooth is removed and the socket is prepared for a future dental implant. If you're having a tooth pulled and bone preservation, this laser might speed up healing and reduce pain.
Charleston, South CarolinaAges 18 years+ - NCT07090122Recruiting
Spinal tumor treatment: ablation plus radiation vs radiation alone
This study compares two treatments for cancer that has spread to the spine. One group receives radiofrequency ablation (a heat-based treatment to destroy tumor cells) plus bone strengthening, followed by radiation. The other group receives radiation alone. The goal is to see which approach better controls pain and prevents spine problems.
Minneapolis, MinnesotaAges 18 years+ - NCT07095608Recruiting
Study on nerve cells and oral cancer pain
This study looks at how certain nerve cells might be involved in oral cancer pain. It aims to find new ways to treat pain by testing tissue samples from people with oral cancer and healthy volunteers.
New York, New YorkAges 18 years+ - NCT06347679Recruiting
Can aromatherapy ease anxiety and pain during dental work?
This study tests whether smelling certain essential oils (aromatherapy) can help reduce anxiety and pain during dental treatments. If you are an adult having a dental procedure, this may be a way to feel more comfortable without medication.
Chengdu, SichuanAges 18–40 - NCT06852859Recruiting
Pain and symptom relief after prostate surgery
This study tracks your pain and other symptoms for three months after surgery for an enlarged prostate. The goal is to learn how well pain relief works during recovery, so doctors can improve care.
AlingsåsAges 50 years+ - NCT06974552Recruiting
Support surfaces during robotic pelvic surgery
This trial compares different support surfaces for patients having robotic surgery in the lower pelvic area while in a steep head-down position. It aims to see which surface helps prevent skin injuries.
Istanbul, AtaşehirAges Any age - NCT06974474RecruitingPhase 4
Guselkumab for pain in psoriatic arthritis
This study tests if guselkumab can reduce pain and inflammation in people with psoriatic arthritis. You may join if standard treatments have not worked well enough or caused side effects.
Rome, ItalyAges 18–80
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,138 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.