Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06704698Recruiting
Pain relief after esophageal surgery: comparing two nerve blocks
This trial compares two types of nerve blocks (paravertebral and epidural) to see which provides better pain relief after esophagectomy. The goal is to find the safest and most effective way to manage pain for patients undergoing this surgery.
Hangzhou, ZhejiangAges 18–80 - NCT06705881Recruiting
Shock wave therapy for athletes with jumper's knee
This trial tests if extracorporeal shock wave therapy (a non-surgical treatment using sound waves) can help athletes with patellar tendinopathy, also known as jumper's knee. It is for people who have had pain in the patellar tendon for at least 6 months and are active in jumping sports.
Kırşehir, CenterAges 18–65 - NCT06664177Recruiting
Pain block comparison for hernia surgery
This trial compares two nerve-block techniques (Quadratus Lumborum block vs. Transversalis Fascia block) to control pain after inguinal hernia surgery. It aims to find which method provides better pain relief and recovery.
IstanbulAges 18–65 - NCT07688902Recruiting
Comparing two injection methods for partial rotator cuff tears
This study compares two ways of injecting a sugar-water solution (5% dextrose) into the shoulder to treat partial rotator cuff tears. It may help reduce pain and improve shoulder function without surgery.
AnkaraAges 18–75 - NCT07683468Recruiting
A self-help kit for pain during sex with endometriosis
This trial tests if a special kit you can use at home helps reduce sexual pain caused by endometriosis. It might offer a new way to manage this common symptom.
StainsAges 18–45 - NCT07487246RecruitingPhase 2
Pain relief study for abortion dilator placement
This study tests whether combining two medications (lidocaine and ketorolac) given as a shot around the cervix can help with pain when placing small sticks (dilators) to prepare for an abortion procedure. If you are 16–24 weeks pregnant and planning an abortion, this trial may help you feel less discomfort.
Chicago, IllinoisAges 18 years+ - NCT07291388Recruiting
Retrolaminar block for lumbar fusion with multimodal pain control
This study tests whether adding a retrolaminar block (a type of back injection) to standard pain medicines helps reduce pain after lumbar spine fusion surgery. It may help you recover with less need for strong painkillers.
Santiago, Santiago MetropolitanAges 18–75 - NCT07672015RecruitingPhase 4
Testing a new pain drug in surgery patients at risk for opioid dependence
This trial tests a new painkiller called suzetrigine for post-surgery pain. It's designed for people whose medical records suggest they may have a higher chance of needing strong painkillers (opioids) long after surgery. We want to see if suzetrigine works better at preventing that.
La Jolla, CaliforniaAges 18 years+ - NCT07504705Recruiting
Comparing two nerve blocks for pain after gallbladder surgery
This trial compares two types of nerve blocks (intertransverse process block and erector spinae plane block) to see which provides better pain relief after gallbladder removal surgery using small incisions (laparoscopic cholecystectomy).
Konya, KonyaAges 18 years+ - NCT07464860Recruiting
Breathwork for older adults after knee surgery
This study tests a breathing exercise program to help older adults recover after knee replacement surgery. Participants practice controlled breathing at home using a smartphone or computer.
Tucson, ArizonaAges 65 years+ - NCT06906939RecruitingEarly Phase 1
Brain stimulation and tai chi for knee arthritis and depression
This pilot study tests if combining brain stimulation (rTMS) with Tai Chi can help knee arthritis pain and improve depression. It compares these two treatments to see which works better for people with both pain and low mood.
Los Angeles, CaliforniaAges 50–95 - NCT06707857Recruiting
TNT Treatment for Rotator Cuff Tendon Pain
This study tests if a treatment called TNT can reduce shoulder pain, improve movement, and help with daily activities in people with rotator cuff tendon problems. It may be a good option if you've had shoulder pain for at least three months.
Lahore, Punjab ProvinceAges 18–65 - NCT06708585Recruiting
Relaxation exercises for first-time mothers before c-section
This study tests whether providing information and teaching progressive muscle relaxation can help first-time mothers feel more relaxed and prepared before a planned cesarean section.
NiğdeAges 18–35 - NCT06710002Recruiting
Home program for sexual pain in menopause
This trial tests a home-based therapy program (telerehabilitation) designed to reduce pain during sex and improve sexual function in menopausal women. The program involves exercises and guidance you can do from home without needing to visit a clinic.
Barcelona, SpainAges 45–65 - NCT06718296Recruiting
Photographic Shoulder Pain Scale Study
This study is creating a new way to measure shoulder pain using pictures. It is for people who have had shoulder pain for more than 3 months, whether from an injury or other causes.
IstanbulAges 18–64 - NCT06718413RecruitingPhase 2
Study on shoulder pain after stroke
This study tests a treatment for shoulder stiffness and pain caused by muscle tightness after a stroke. It focuses on people who still have some limited shoulder movement and may help improve range of motion and comfort.
Baltimore, MarylandAges 18 years+ - NCT06718569Recruiting
Pain in Inflammatory Joint Diseases
This study looks at pain in people with inflammatory joint diseases. It aims to understand how pain changes when you start or switch to a newer type of arthritis medication.
OsloAges 18 years+ - NCT06719232Recruiting
Testing a new way to give bladder treatment without a catheter
This study tests a catheter-free method for delivering medication directly into the bladder. It may help patients with bladder pain, recurrent infections, bladder cancer, or cystitis after radiation or chemotherapy.
BudapestAges 18–80 - NCT06721819RecruitingPhase 3
Sleep and brain training before heart surgery to prevent delirium
This study tests whether a combination of sleep therapy, brain games, and light exercise before heart surgery can help prevent confusion or disorientation (delirium) after the operation. Participants will be asked to use a tablet and fitness tracker daily for about an hour before their surgery.
Boston, MassachusettsAges 60 years+ - NCT06723353Recruiting
Combined therapy for belly separation in new mothers
This trial tests if a gentle hands-on treatment (visceral manipulation) plus special tape (kinesio taping) can help close the gap in your belly muscles, reduce pain, stop bladder leaks, and improve your pelvic floor strength and overall well-being after childbirth.
Karachi, SindhAges 35–45 - NCT06725862Recruiting
Pain relief methods for undescended testis surgery in children
This study compares two different numbing injections (caudal block vs retrolaminar block) given before surgery to see which one provides better pain control for children aged 1-7 undergoing undescended testis surgery.
IstanbulAges 1–7 - NCT06729294Recruiting
Does music help during knee replacement surgery?
This study tests if listening to music during knee replacement surgery under spinal anesthesia can lower anxiety, pain, and stress hormone levels. It may help make the experience calmer for patients.
Kocasinan, KayseriAges 18 years+ - NCT06731647RecruitingPhase 2
Anti-inflammatory drugs for pleurodesis in pneumothorax
This trial tests whether using non-steroidal anti-inflammatory drugs (NSAIDs) during pleurodesis (a procedure to seal the lung lining) helps people with a collapsed lung (pneumothorax). It aims to see if these drugs can improve outcomes.
AmiensAges 18 years+ - NCT06731985Recruiting
Shorter sling tape follow-up study
This study looks at how well and how safely a shorter type of sling tape (used to treat stress urinary incontinence) works over time. It may help women who had this specific surgery between 2009 and 2020 understand their long-term results.
LorenskogAges 25–90
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.