Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,261 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06713044Recruiting
Quran recitation or music for pain after leg surgery
This trial tests whether listening to Quranic recitation or classical music can reduce pain and inflammation after lower-leg orthopedic surgery. It may help Muslim patients manage pain without extra medication.
Purwokerto, Central JavaAges 18–60 - NCT06731335RecruitingPhase 2
Psilocybin for chronic nerve pain that hasn't improved with other treatments
This study tests whether psilocybin (a compound found in certain mushrooms) can help reduce chronic nerve pain that has not responded well to standard medications. You will receive study treatment plus psychotherapy to see if it improves your pain.
Toronto, OntarioAges 18–65 - NCT06763653Recruiting
Low-frequency device for chronic low back pain
This trial tests a new device that uses very low-frequency electrical pulses to treat chronic low back pain. It is for people whose pain hasn't improved with other treatments and who are not candidates for stronger therapies.
Norwood, South AustraliaAges 22 years+ - NCT06769373Recruiting
Whirlpool and contrast bath for CRPS after wrist fracture
This study tests whether warm water whirlpool baths or alternating hot and cold water baths (contrast bath) can help reduce pain and improve function in people with Complex Regional Pain Syndrome (CRPS) after a wrist fracture that was treated without surgery.
Afyonkarahisar, AfyonkarahisarAges 18–70 - NCT06775535Recruiting
Spinal cord stimulation trial for chronic pain
This trial tests a closed-loop spinal cord stimulator that adjusts stimulation based on nerve signals. It may help people with chronic pain who are already scheduled to try this type of device.
RoeselareAges 18 years+ - NCT06784908Recruiting
Stress and pain study for people living with HIV
This study looks at how stress affects pain in people with HIV. It may help find better ways to manage pain in this group.
New Haven, ConnecticutAges 18–68 - NCT06785389Recruiting
How fear before surgery affects pain and recovery
This study looks at how feeling scared or anxious before surgery might affect your pain and recovery afterward. It aims to help improve care for future patients.
Las Palmas de Gran Canaria, Las PalmasAges 18 years+ - NCT06798233Recruiting
Hip pain questionnaire for caregivers of non-walking children
This study is creating a new questionnaire to help caregivers describe hip pain in children who cannot walk or speak. It aims to improve how doctors assess and treat hip pain in these children.
Pisa, ItalyAges 1–20 - NCT06803732Recruiting
Pain after robotic, endoscopic or open neck surgery for thyroid cancer
This trial compares pain levels after three different surgical methods for removing cancerous lymph nodes in the neck. It may help patients with thyroid cancer that has spread to neck lymph nodes understand which approach causes less discomfort.
Shanghai, Shanghai MunicipalityAges Any age - NCT06813352Recruiting
Using facial expressions to recognize pain in fibromyalgia
This study uses artificial intelligence to look at facial expressions and other body signals to help recognize pain in people with fibromyalgia. It may lead to better ways to measure and treat pain.
Belo Horizonte, Minas GeraisAges 18–65 - NCT06817018RecruitingPhase 2
Ginger root extract for chronic sciatica pain
This study tests whether a ginger root extract can reduce pain in people with long-term sciatica. If you have had sciatic pain for at least 3 months and are not on blood thinners, you may be able to join.
Lubbock, TexasAges 18–85 - NCT06827730Recruiting
Ultrasound for chest or belly pain in the ER
This study uses a quick bedside ultrasound (called PoCUS) to help doctors diagnose chest or belly pain in the emergency room. If you join, you'll get this ultrasound early in your visit to see if it helps find the cause of your pain faster and more accurately.
BrusselsAges 18 years+ - NCT06847763Recruiting
Online pain education for chronic low back pain
This study tests an online class that teaches you about how your brain and nerves process pain, to help you manage chronic low back pain. It is a long-term program you can join from home.
Istanbul, AtasehirAges 20–60 - NCT06854718Recruiting
Pain Management Study for People with Dementia
This study tests a new approach to help people with dementia who have chronic pain. It looks at how caregivers can support pain management at home.
Durham, North CarolinaAges 50 years+ - NCT06856733Recruiting
Better opioid management for long-term non-cancer pain
This study tests a new way to help people who have been taking opioids for chronic pain (not caused by cancer) for at least 90 days. The goal is to improve treatment and reduce risks, such as developing tolerance or side effects, while still managing pain effectively.
Strängnäs, SörmlandAges 18–70 - NCT06861920RecruitingPhase 4
NSAID use for painful periods to prevent chronic pelvic pain
This study tests whether using NSAIDs (like naproxen) for painful periods can help prevent chronic pelvic pain later on. It's for people with regular, painful periods who are otherwise healthy.
Evanston, IllinoisAges 18–35 - NCT06869668Recruiting
Chronic low back pain and quality of life study
This study looks at how long-term back pain affects your daily life, physical abilities, and how you feel about moving. It aims to find links between pain, fear of movement, and overall well-being.
Istanbul, BuyukcekmeceAges 18–50 - NCT06869928Recruiting
Pain and irritability pathway for children with neurological conditions
This study tests a special care plan for children who have both a significant neurological condition and unexplained pain or irritability. The goal is to help families and doctors work together to better understand and manage these distressing symptoms.
Vancouver, British ColumbiaAges 6 months–18 years - NCT06886906Recruiting
Movement and Pain in Older Adults
This study explores how movement and physical activity relate to pain in older adults with muscle or joint pain. It could help you understand your pain patterns and find better ways to manage them.
Indianapolis, IndianaAges 55–85 - NCT06899685Recruiting
Kinesio taping vs. tool-assisted massage for neck pain relief
This study compares two non-invasive treatments for neck pain caused by muscle knots in the upper trapezius (the muscle between your neck and shoulder). The goal is to see which approach better reduces pain, improves neck movement, and helps with daily function.
Banī SuwayfAges 19–23 - NCT06903962Recruiting
Mind-body program for chronic arm or hand pain
This trial tests whether a mind-body program can help people with long-term pain in their upper arm, forearm, or hand that is not caused by a clear physical injury. It focuses on retraining how your brain responds to pain triggers.
Boston, MassachusettsAges 18–60 - NCT06906107Recruiting
Neck pain study: testing a personalized treatment approach
This study is testing a method to see which neck pain patients benefit most from manual therapy and exercise. You may be eligible if you have neck pain (with or without arm symptoms) and have not had recent whiplash, neck surgery, or certain other conditions.
Rochester, MinnesotaAges 18–70 - NCT06906211Recruiting
Ultrasound for chronic back pain in veterans
This trial tests if a gentle ultrasound treatment to a specific part of the brain can help veterans with chronic back pain. It aims to see if targeting the insula can reduce pain that spreads to other areas of the body.
Washington D.C., District of ColumbiaAges 21–75 - NCT06918535Recruiting
Relaxation vs muscle technique for neck pain in computer users
This study compares two therapies for neck pain in people who use computers for long hours. The goal is to see which method better reduces pain and stiffness from tight neck muscles.
Karachi, SindhAges 20–45
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,261 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.