Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,136 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06827262Recruiting
A procedure for vertebrogenic back pain relief
This trial tests a minimally invasive procedure that uses a special device to target and treat nerve-related back pain coming from the vertebrae (the bones in your spine). It may offer lasting relief without more major surgery.
Flagstaff, ArizonaAges 18 years+ - NCT06827730Recruiting
Ultrasound for chest or belly pain in the ER
This study uses a quick bedside ultrasound (called PoCUS) to help doctors diagnose chest or belly pain in the emergency room. If you join, you'll get this ultrasound early in your visit to see if it helps find the cause of your pain faster and more accurately.
BrusselsAges 18 years+ - NCT06817018RecruitingPhase 2
Ginger root extract for chronic sciatica pain
This study tests whether a ginger root extract can reduce pain in people with long-term sciatica. If you have had sciatic pain for at least 3 months and are not on blood thinners, you may be able to join.
Lubbock, TexasAges 18–85 - NCT06807177Enrolling by invitation
Collagen injections for chronic neck pain
This trial tests if collagen injections into the neck can reduce chronic muscle pain and whether certain blood markers can show how well the treatment works. It may help if you have had neck pain for more than 12 weeks.
WarsawAges 18–65 - NCT06803732Recruiting
Pain after robotic, endoscopic or open neck surgery for thyroid cancer
This trial compares pain levels after three different surgical methods for removing cancerous lymph nodes in the neck. It may help patients with thyroid cancer that has spread to neck lymph nodes understand which approach causes less discomfort.
Shanghai, Shanghai MunicipalityAges Any age - NCT06813352Recruiting
Using facial expressions to recognize pain in fibromyalgia
This study uses artificial intelligence to look at facial expressions and other body signals to help recognize pain in people with fibromyalgia. It may lead to better ways to measure and treat pain.
Belo Horizonte, Minas GeraisAges 18–65 - NCT06798233Recruiting
Hip pain questionnaire for caregivers of non-walking children
This study is creating a new questionnaire to help caregivers describe hip pain in children who cannot walk or speak. It aims to improve how doctors assess and treat hip pain in these children.
Pisa, ItalyAges 1–20 - NCT06798493Enrolling by invitation
CRPS and chronic pain measurement study
This study is testing a new way to measure CRPS symptoms and other chronic pain in one arm or leg. It aims to help doctors better understand and treat your condition.
New York, New YorkAges 18 years+ - NCT06785389Recruiting
How fear before surgery affects pain and recovery
This study looks at how feeling scared or anxious before surgery might affect your pain and recovery afterward. It aims to help improve care for future patients.
Las Palmas de Gran Canaria, Las PalmasAges 18 years+ - NCT06784908Recruiting
Stress and pain study for people living with HIV
This study looks at how stress affects pain in people with HIV. It may help find better ways to manage pain in this group.
New Haven, ConnecticutAges 18–68 - NCT05505188Recruiting
Predicting long-term pain after head and neck radiotherapy
This study looks for ways to predict and improve pain you may have months after radiotherapy for first head and neck cancer. It may help doctors better anticipate pain and support patients during recovery.
CaenAges 18 years+ - NCT06052384Recruiting
Better sleep care for chronic pain patients
This study tests whether adding a sleep specialist to your pain care team can help you feel better. If you have chronic pain (lasting over 3 months) and are now seeing a pain doctor for the first time, you may be able to join.
Le Puy-en-VelayAges 18 years+ - NCT05494502Recruiting
Nerve block to reduce long-term pain after breast surgery
This trial tests whether a specific pain-numbing nerve block given during mastectomy can reduce chronic (long-lasting) pain after breast cancer surgery. It may help some people use less pain medicine later by lowering nerve-related pain after surgery.
Beijing, Beijing MunicipalityAges 18–85 - NCT06741579RecruitingPhase 3
Pain relief study for nerve injury pain
This trial tests how well two types of peripheral nerve stimulation (PNS) devices relieve chronic pain caused by a single nerve injury. It looks for people who already have a referral for PNS therapy as part of their usual care and who have gotten at least 50% relief from a diagnostic nerve block.
Palo Alto, CaliforniaAges 18 years+ - NCT06726018Enrolling by invitation
Brain stimulation and pain conditioning in healthy adults
This study explores how the brain processes pain by using gentle magnetic pulses (TMS) and repeated cold or pressure stimuli. It is for healthy people who are pain-free and aims to understand pain control better.
El Paso, TexasAges 18–75 - NCT06704061Recruiting
Online yoga vs ACT for chronic pain in veterans
This study compares online yoga with Acceptance and Commitment Therapy (ACT), a type of talk therapy, to see which helps veterans better manage long-lasting muscle or bone pain. You can join from home through the internet.
Palo Alto, CaliforniaAges 18 years+ - NCT06692400Recruiting
Suctioning, pain, and blood markers in intubated patients
This study looks at how routine suctioning of the breathing tube affects pain levels and certain substances in the blood in adults who are on a breathing machine for serious infections like flu, pneumonia, COVID, or sepsis. It may help doctors better understand and manage your comfort during this procedure.
Loma Linda, CaliforniaAges 18 years+ - NCT06686875Enrolling by invitation
Chronic belly pain after sleeve gastrectomy study
This study looks at long-term belly pain in people who had a sleeve gastrectomy 3 months to 5 years ago. It aims to understand the pain better to help future patients.
WarsawAges 18 years+ - NCT06635213Recruiting
Desensitisation and pain education for carpal tunnel syndrome
This study tests whether desensitisation therapy and pain neuroscience education help people with carpal tunnel syndrome who have a type of pain called 'nociplastic' (pain without clear tissue damage). It aims to reduce pain and improve function.
KütahyaAges 18–65 - NCT06671925Recruiting
Support program for chronic pain and loneliness in older adults
This trial tests a program led by community health workers to help older adults manage chronic pain and reduce loneliness. It aims to improve your well-being through support and guidance.
Ann Arbor, MichiganAges 60 years+ - NCT06655844Recruiting
Sana Device for chronic pain from Lyme disease
This study tests the Sana device—a special light and sound tool—to see if it can help reduce chronic nerve pain in people with Post-Treatment Lyme Disease Syndrome. You may be able to join if you have ongoing nerve pain after Lyme treatment and meet a few basic health and medication rules.
New York, New YorkAges 18 years+ - NCT06635174Enrolling by invitation
Sugar water for pain relief before infant catheter
This study tests if giving a small amount of sugar water (50% dextrose) by mouth can help reduce pain in babies who need a bladder catheter. It might be a gentler way to comfort infants during this procedure.
Muscat, Muḩāfaz̧at MasqaţAges 1 day–3 months - NCT06632535Recruiting
Group visits and chiropractic care for older adults with chronic spine pain
This study tests whether group medical visits combined with chiropractic care can help older adults with chronic neck or back pain. If you join, you'll receive chiropractic treatments and attend group visits to learn pain management strategies.
Boston, MassachusettsAges 65 years+ - NCT05540548Recruiting
Podiatry assessment for balance and pain in chronic back pain
This study looks at whether a foot and posture specialist can help measure how balance relates to the pain you feel in chronic low back pain. It may help doctors better understand what to focus on for pain that lasts for months.
ValenciennesAges 18 years+
Hear when a new Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,136 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.