Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06493175Recruiting
Large language model for emergency chest pain triage
This study tests whether a large language model (a type of artificial intelligence) can help sort patients with chest pain in the emergency room. It aims to make triage faster and more accurate for adults coming in with chest pain.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06500780Recruiting
Pain and depression support for African Americans
This study tests a program that helps people with both long-term pain and depression. It includes coaching and support to help you feel better and manage your health. The study is for Black or African American adults.
Indianapolis, IndianaAges 18 years+ - NCT06507267Recruiting
Pain and symptoms in pelvic congestion syndrome
This study looks at how pain and other symptoms relate to a condition called pelvic congestion syndrome, which happens when veins in the pelvis become enlarged. It may help doctors better understand and treat this cause of long-term pelvic pain.
IstanbulAges 18–50 - NCT06507345Recruiting
Non-opioid pain relief after breast surgery
This trial tests whether non-opioid pain medicines can effectively control pain after mastectomy or lumpectomy, allowing you to go home the same day without needing strong opioids.
Montreal, QuebecAges 18 years+ - NCT06511674Recruiting
Nerve pain risk study for cancer patients
This study looks at why some people with cancer develop nerve pain (neuropathic pain) during treatment. By tracking your health and symptoms, researchers hope to find ways to predict and prevent this side effect.
AjaccioAges 18 years+ - NCT06520150Recruiting
Comparing two numbing methods for S-ICD heart device placement
This study compares two ways of numbing the chest area (regional anesthesia) for people getting an S-ICD heart device. The goal is to find which method works better and is safer for patients who are at higher risk for general anesthesia.
Wroclaw, Lower Silesian VoivodeshipAges 18–90 - NCT06526143Recruiting
Pain care pathway for recent veterans
This study tests a new approach to help veterans manage pain in their back, neck, knee, or shoulder after leaving the military. It includes phone or online check-ins and support tailored to your needs.
West Haven, ConnecticutAges 18 years+ - NCT06534372Recruiting
Factors affecting chronic pain after open-heart surgery
This study looks at factors that may lead to long-term pain after open-heart surgery. It follows patients who have coronary bypass or valve surgery to understand what might cause ongoing pain.
Ankara, AnkaraAges 18–80 - NCT06544525Recruiting
Pain test to predict physical therapy results for back pain
This trial tests whether a simple pain test can predict how much you will improve with physical therapy for chronic low back pain. It looks at how your body naturally handles pain, which may help tailor your treatment.
Fort Sam Houston, TexasAges 18–64 - NCT06566144Recruiting
Adding osteopathy to standard care for chronic low back pain
This study tests whether adding osteopathy (a type of hands-on therapy) to standard care helps people with long-term low back pain feel better and move more easily. It is for adults with chronic, nonspecific back pain that has lasted at least 6 weeks.
São PauloAges 18–70 - NCT06574009RecruitingPhase 4
Better options for chronic cancer pain in veterans
This study tests if switching from long-term opioid painkillers to buprenorphine (a different type of pain medication) can provide better pain relief for veterans who have had cancer but are currently cancer-free. It aims to find a safer and more effective way to manage chronic pain.
Indianapolis, IndianaAges 18–99 - NCT06351046Recruiting
Preventing chronic pain from getting worse
This trial tests a virtual reality program to see if it can help prevent long-term pain from becoming more severe. You may be eligible if you have had pain for at least 3 months and rate your average pain as moderate or higher.
Copenhagen, København Ø.Ages 18 years+ - NCT06614322RecruitingPhase 2
Testing Pain Sensitivity and Pain Relief for Nerve Pain in Feet
This study looks at how people with long-term nerve pain in their feet respond to pain relief. It aims to match the right treatment to each person based on their pain sensitivity.
Boston, MassachusettsAges 18–80 - NCT06621914Recruiting
Blood flow restriction training for military with leg injuries
This trial tests a low-weight exercise program using a special cuff on the leg (blood flow restriction) to see if it helps military personnel recover from leg injuries faster. It could be an option if pain is stopping you from doing normal rehab.
Loughborough, LeicestershireAges 18–55 - NCT06632535Recruiting
Group visits and chiropractic care for older adults with chronic spine pain
This study tests whether group medical visits combined with chiropractic care can help older adults with chronic neck or back pain. If you join, you'll receive chiropractic treatments and attend group visits to learn pain management strategies.
Boston, MassachusettsAges 65 years+ - NCT06635213Recruiting
Desensitisation and pain education for carpal tunnel syndrome
This study tests whether desensitisation therapy and pain neuroscience education help people with carpal tunnel syndrome who have a type of pain called 'nociplastic' (pain without clear tissue damage). It aims to reduce pain and improve function.
KütahyaAges 18–65 - NCT06655844Recruiting
Sana Device for chronic pain from Lyme disease
This study tests the Sana device—a special light and sound tool—to see if it can help reduce chronic nerve pain in people with Post-Treatment Lyme Disease Syndrome. You may be able to join if you have ongoing nerve pain after Lyme treatment and meet a few basic health and medication rules.
New York, New YorkAges 18 years+ - NCT06661642Recruiting
Predicting pain after planned surgery
This study looks at whether we can predict how much pain you will feel after surgery. It aims to help doctors better manage pain after your operation.
AalborgAges 18 years+ - NCT06696573Recruiting
Anti-inflammatory drugs for pain during medical abortion
This study tests whether giving anti-inflammatory drugs before or during a medical abortion (13–22 weeks) can help prevent pain better than treating pain once it starts. If you're eligible, taking part may help improve pain management for future patients.
Ho Chi Minh CityAges 18 years+ - NCT06704061Recruiting
Online yoga vs ACT for chronic pain in veterans
This study compares online yoga with Acceptance and Commitment Therapy (ACT), a type of talk therapy, to see which helps veterans better manage long-lasting muscle or bone pain. You can join from home through the internet.
Palo Alto, CaliforniaAges 18 years+ - NCT06706037Recruiting
Reformer exercise for chronic muscle and joint pain
This study tests if Reformer Pilates exercises can reduce pain for people with long-term muscle or joint pain. It may help you feel better and move more easily.
Ankara, Select StateAges 30–50 - NCT07688915Recruiting
High-intensity laser vs. steroid injection for chronic back and leg pain from a herniated disc
This study compares two treatments for long-lasting low back and leg pain caused by a herniated disc: high-intensity laser therapy and a steroid shot near the spine. Researchers want to see which option works better to reduce pain.
AnkaraAges 18–65 - NCT07683273Enrolling by invitation
Breathing exercises for neck and upper back pain
This study tests whether diaphragmatic breathing exercises can help reduce chronic, non-specific neck and upper back pain. If you have this type of pain that is not caused by an injury or disease, you may be able to join.
Trabzon, OrtahisarAges 18–60 - NCT07428070Recruiting
Exercise program for rotator cuff shoulder pain
This trial tests if a specially designed exercise program can reduce shoulder pain related to the rotator cuff. It may help if you've had shoulder pain for more than three months.
IstanbulAges 18–75
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.