Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,142 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07872163Recruiting
Breathing exercises for pain, stress, and posture in young adults
This trial tests whether simple diaphragmatic breathing exercises can improve pain, breathing discomfort, posture, body awareness, anxiety, and depression in healthy young adults. If you're generally healthy and not already doing regular breathing or posture exercises, you may qualify.
Kirikkale, YahşihanAges 18 years+ - NCT07854028Recruiting
Muscle release techniques for low back pain
This study tests two hands-on treatments—strain counter strain and muscle energy technique—to ease low back pain and improve movement. It may help if you have had low back pain for 3–6 months and have specific tender spots in your back muscles.
Lahore, Punjab ProvinceAges 20–40 - NCT05325580RecruitingPhase 3
IV magnesium vs placebo for sudden non-injury headaches
This trial tests whether giving magnesium sulfate through a vein in the emergency room can reduce sudden (non-injury) acute headaches compared with a placebo. It may help people whose headache comes on suddenly and is not caused by an injury.
MonastirAges 18–85 - NCT07867951Recruiting
Pain after two root canal medicines
This study compares two medicines placed inside a tooth during root canal treatment to see which one reduces pain better afterward. It may help people with an infected tooth causing pain.
Swāt, KpkAges 16–50 - NCT07857655RecruitingPhase 4
Intraoperative methadone for pain after head and neck cancer surgery
This trial tests whether giving methadone during your head and neck cancer surgery helps control pain right after the operation. Methadone is a long-acting painkiller that might reduce pain for up to a day or more, potentially improving your recovery experience.
Portland, OregonAges 18–89 - NCT07860697Recruiting
MRI study of back pain and spine changes
This study looks at MRI images of the lower back to see how body fat, back muscles, and small spine joints relate to long-term back pain. It may help doctors understand back pain better and improve future treatments.
Istanbul, IstanbulAges 18–75 - NCT06294951Recruiting
Brain Scans for Bladder Pain Syndrome
This study uses brain scans (fMRI) to learn how bladder pain syndrome affects the brain. It compares women with bladder pain to those without, to better understand symptoms and improve future treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06074744Recruiting
Nerve blocks for knee replacement pain relief
This study compares two types of nerve blocks (subsartorial and femoral) to see which provides better pain control after knee replacement surgery. Both are injections that numb the nerves around your knee to help with recovery.
LucerneAges 18 years+ - NCT06308328Recruiting
Mucosal contouring study for oral pain from radiation
This study tests a new way to reduce mouth and throat pain caused by radiation therapy for nasopharyngeal cancer. It may help if you are currently getting radiation or chemoradiation and have mouth sores.
Guangzhou, GuangdongAges 18 years+ - NCT06372054Recruiting
Predicting health risks for Italian Air Force members
This study aims to develop smart risk models using your body's data (like proteins and genes) along with personal exposure readings. It will help predict health risks for Italian Air Force personnel. You will wear a monitor and give samples, then be followed over time.
MilanAges 26–38 - NCT06405776Recruiting
Lidocaine for pain and survival after bowel surgery in older adults
This study tests whether a drug called lidocaine, given during surgery, can help control pain after colon or rectal surgery and possibly improve long-term survival in older adults. The goal is to see if lidocaine offers better pain relief and recovery compared to standard care.
SichuanAges 60 years+ - NCT06406244Recruiting
TEAS for chronic pain after liver surgery
This trial tests whether a gentle, needle-free electrical stimulation on certain points on the body (called TEAS) can help reduce chronic pain after liver surgery and improve long-term survival. It may be a good option if you are scheduled for a liver removal and want to explore non-drug pain relief.
ChengduAges 18–80 - NCT02355457Recruiting
Blood marker study in new heart attack symptoms
This study looks at blood “biomarkers” (signals in blood tests) in people who arrive with symptoms that could be a heart attack. It may help doctors spot and manage acute heart problems sooner and more accurately.
HamburgAges 18 years+ - NCT07853300Enrolling by invitation
Virtual reality for comfort during colonoscopy
This study tests whether using virtual reality (a computer-generated 3D environment you can see and hear) during a colonoscopy can reduce pain, anxiety, and embarrassment. If it works, it could make the procedure more comfortable for people who have it without sedation.
Kocaeli, İzmitAges 18–65 - NCT07851233Enrolling by invitation
Patient education on sling use after shoulder surgery
This study looks at how different ways of teaching patients about sling use after shoulder surgery may affect their recovery. If you join, you may receive extra education materials to help you use your sling correctly.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06426251Recruiting
Light therapy for knee replacement recovery
This trial tests whether a special light therapy (photobiomodulation) can help reduce pain and speed healing after total knee replacement. If you're having knee replacement and don't have complications like infection or open wounds, you may be eligible.
HsinchuAges 20 years+ - NCT06414083Recruiting
Comparing ablation methods for endometriosis surgery
This study compares two different ablation techniques used during surgery to remove endometriosis lesions. It aims to see which method works better for relieving pelvic pain symptoms.
Cincinnati, OhioAges 18 years+ - NCT07844772Recruiting
Psoriasis treatment and nerve pain study
This study looks at how different psoriasis treatments affect nerve-related pain and sensitivity. It compares patients on biologic injections, standard pills, or creams to see if treatment type matters for pain and skin symptoms.
Istanbul, IstanbulAges 18 years+ - NCT07849244Enrolling by invitation
Sacroiliac joint fusion for mobility and pain relief
This study tests a surgical procedure to fuse the sacroiliac joint (the joint connecting your lower spine and pelvis) to reduce pain and improve mobility and function. It is for people with one-sided SI joint pain that has not improved with other treatments.
Post Falls, IdahoAges 21 years+ - NCT07845136Recruiting
Riddles to reduce pain and fear during child cast placement
This study tests whether solving riddles during cast placement helps children feel less pain, fear, and anxiety. It is a simple, non-drug approach that may make the experience more comfortable for your child.
Kilis, CentralAges 6–12 - NCT07850258Recruiting
Laser vs standard treatment for severe tooth pain
This study compares two ways to treat a severely inflamed tooth nerve (pulpitis) that causes ongoing pain. One method uses a laser, while the other uses standard tools, to see which is better at relieving pain and saving the tooth.
Kütahya, MerkezAges 12–40 - NCT07847541RecruitingPhase 2
Botulinum toxin injections for jaw muscle pain
This trial tests whether botulinum toxin (Botox) injections can reduce pain in the jaw muscles for people with temporomandibular joint (TMJ) disorders that haven't improved with other treatments. It may help if you have ongoing jaw pain and muscle tightness.
IslamabadAges 18–60 - NCT07846501Enrolling by invitation
How thoughts and feelings affect fibromyalgia impact
This study looks at how your thoughts, emotions, and attitudes about your illness affect how fibromyalgia impacts your daily life. By filling out questionnaires, you can help doctors understand what matters most to people with fibromyalgia.
Bilecik, BilecikAges 18 years+ - NCT07843784Enrolling by invitation
Chatbot pain management for knee osteoarthritis
This trial tests a chatbot program to help people manage knee osteoarthritis pain. You’d use your smartphone to get support and exercises at home, which might help reduce pain and improve daily life.
Hong Kong, Hong KongAges 18 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,142 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.