Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06460402Enrolling by invitation
Ice packs and warm baths after hemorrhoid surgery
This trial tests whether using ice packs and warm baths after hemorrhoid surgery helps wounds heal faster and reduces pain more than standard care. If you are having surgery to remove hemorrhoids, this study may offer a simple, gentle way to help you recover.
Kaohsiung CityAges 18–80 - NCT06455423Enrolling by invitation
ELDOA and adjustments for upper back pain and posture
This study tests whether adding a gentle stretching technique (ELDOA) to standard upper back adjustments can improve upper back pain, reduce hunching, and correct forward head posture. It is for adults with upper back discomfort and postural issues.
Islamabad, FederalAges 19–44 - NCT06430918Enrolling by invitation
Nerve pain and sleep quality in knee osteoarthritis
This study looks at how nerve pain and sleep quality are related in people with knee osteoarthritis. It aims to help doctors better understand and treat pain.
IzmirAges 18–80 - NCT06407115Enrolling by invitation
Pain care support for rural patients
This study tests a nurse-led program to help people living in rural areas manage chronic pain. You'll work with a care manager who can support your pain treatment goals.
Winston-Salem, North CarolinaAges 18 years+ - NCT06221280Enrolling by invitation
Nerve blocks for pain after cesarean and depression
This study tests whether a nerve block (extra numbing medicine) given during a cesarean section can help with pain after delivery and may reduce the risk of postpartum depression. The trial compares the nerve block to standard care.
Kahramanmaraş, KahramanmaraşAges 18 years+ - NCT06185816RecruitingPhase 2/Phase 3
Non-invasive pulsed radiofrequency for nerve pain
This trial tests a non-invasive treatment called pulsed radiofrequency for people with chronic nerve pain after an injury. It uses a device that sends short bursts of energy to the painful area to help reduce pain without surgery.
Redwood City, CaliforniaAges 18 years+ - NCT06100926Enrolling by invitation
Virtual reality for chronic muscle pain
This study tests whether virtual reality (VR) can help reduce chronic muscle pain that is not caused by cancer. If you have fibromyalgia or similar long-lasting muscle pain, you may be able to join.
Udine, Friuli Venezia GiuliaAges 18–50 - NCT06077422Enrolling by invitationPhase 2/Phase 3
Comparing two pain blocks for heart surgery recovery
This trial compares two types of pain blocks (Exparel vs. Marcaine) given during heart surgery to see which one provides better pain relief. If you are scheduled for a heart surgery through a small or full chest incision, you may be able to join.
New Brunswick, New JerseyAges 18 years+ - NCT06063902Enrolling by invitation
Long-term opioid therapy for chronic pain
This study looks at the risks and benefits of long-term use of opioids (strong painkillers) for chronic pain that is not caused by cancer. It aims to help doctors and patients make better decisions about pain management.
UppsalaAges 18 years+ - NCT06054802Enrolling by invitation
Sleep and pain after spine surgery in teens
This study looks at how sleep quality before and after spine surgery affects pain recovery. It uses text messages to check in with participants, so a mobile device is needed.
Columbus, OhioAges 10–18 - NCT05944354Enrolling by invitation
Wearable system to study spine health for military readiness
This study tests whether a wearable setup can measure spine health during training and daily movement. It may help improve how military members with or without neck or low back pain are monitored and supported.
Luke Air Force Base, ArizonaAges 18–64 - NCT05809648Enrolling by invitation
Testing a special scan to better diagnose heart blood-flow problems
This study checks whether a magnet-based heart scan (magnetocardiography) can more accurately find “true ischemia,” which means reduced blood flow to the heart, in people who come to the emergency room with chest pain. It aims to help doctors tell which chest pain is truly from heart blood-flow problems.
Rochester, MinnesotaAges 18 years+ - NCT05772468Enrolling by invitation
Virtual pain care for people getting wound treatment
This trial tests a virtual (VR) pain-care approach during wound care procedures. It may help reduce how painful the treatments feel, especially for people who have had very painful wound care before.
Amsterdam, North HollandAges 18 years+ - NCT05745129Enrolling by invitation
AI tool for personalized care decisions in spine problems
This trial looks at using an artificial intelligence (AI) tool to help guide care choices for people with spine problems. It may help doctors assess whether you need surgery or a different approach, especially when disc herniation isn’t the main issue.
Oslo, NorgeAges 18–80 - NCT05673551Enrolling by invitation
VR during at-home burn dressing changes for kids
This trial tests whether virtual reality (VR) can help children feel better during daily burn dressing changes at home. It will study comfort and pain around the first time you do dressings after leaving the hospital.
Columbus, OhioAges 6–17 - NCT05561153Enrolling by invitation
Study of knee movement issues in patellofemoral pain
This study looks at how the nerves and muscles are working in people with patellofemoral pain (pain around the kneecap). It may help researchers understand what drives the pain and how it might be treated.
AnkaraAges 18–40 - NCT05513417Enrolling by invitation
Digital pelvic health program for women with pelvic pain
This study tests a digital (phone/app-based) program to help women with pelvic pain or pelvic health symptoms. It may help by guiding pelvic-focused exercises and care, especially if you’re recovering from pelvic surgery or managing ongoing symptoms.
Draper, UtahAges 18–99 - NCT05477004Enrolling by invitation
Study of ketamine infusions for ongoing chronic pain
This study is observing people with chronic pain who are getting ketamine infusions at Stanford. You may help by completing email surveys about how you feel, which can help the team understand the treatment’s impact.
Stanford, CaliforniaAges 18 years+ - NCT05231460Enrolling by invitationPhase 4
Pain plan study for people before bariatric surgery
This study tests a specific pain-management plan for people who are scheduled for sleeve gastrectomy (done by laparoscopy or robotics). The goal is to find how to control pain safely around the time of surgery while avoiding certain risks and medication issues.
Phoenix, ArizonaAges 18 years+ - NCT05183503Enrolling by invitation
Study of pain, stress, anxiety, and depression in jaw disorder
This study looks at how chronic jaw pain from temporomandibular disorder (TMD) relates to stress, anxiety, and depression in adults. Your results may help researchers better understand what affects symptoms and how people respond to care.
WroclawAges 18–80 - NCT05115461Enrolling by invitation
Study pain and balance in lumbar disc nerve pain
This trial studies how nerve pain from a slipped/herniated low-back disc affects postural (balance) stability. It may help researchers understand better ways to support balance and reduce nerve-related pain symptoms.
IzmirAges 18–60 - NCT04732507Enrolling by invitationPhase 2
Trigger point injections: test fewer needlings for pain relief
This Phase 2 study tests whether doing a smaller number of needle “treatments” during trigger point injections works as well for myofascial pain. If you’ve tried safer treatments without success (or can’t do physical therapy), you may be eligible to help answer the best treatment approach.
Tucson, ArizonaAges 18 years+ - NCT07361796Recruiting
Venlafaxine to prevent nerve pain after shingles
This trial tests whether the drug venlafaxine, usually used for depression, can help prevent long-term nerve pain (postherpetic neuralgia) after a shingles infection. If you are currently experiencing shingles pain, joining this study might reduce your chances of developing chronic pain later.
BeijingAges 18 years+ - NCT07800403Recruiting
Nanoparticle disinfection for root canal infection in diabetes
This trial tests a new disinfection approach during root canal treatment for people with type 2 diabetes who have an infected front tooth. It aims to improve the effectiveness of the cleaning step, which may help treat the infection better.
MinyaAges 18–40
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.