Clinical trials
PARKINSON DISEASE (Disorder) clinical trials
Below are recruiting parkinson disease (disorder) clinical trials, each written for real people, not researchers. We’re tracking 497 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05413291Recruiting
Study of movement disorders over time
This study follows people (or family members of people) who have or might have a movement disorder to better understand how symptoms change over time. You may be asked to attend study visits and complete study procedures for the duration of the study.
Bethesda, MarylandAges 2–100 - NCT05516719Recruiting
Study tracking I2BS in Parkinson’s over time
This study follows people with Parkinson’s to see how “I2BS” changes over time using special brain scans and other tests. It may help researchers better understand Parkinson’s and improve how it’s measured in future trials.
Exeter, DevonAges 25 years+ - NCT05516732Recruiting
Testing serotonin activity in the brain in people with Parkinson’s
This study uses special scans to measure how serotonin is released in parts of the brain involved in movement in Parkinson’s disease. It may help researchers understand disease changes and the role of serotonin systems in movement problems.
Exeter, DevonAges 25–85 - NCT05518617Recruiting
Imaging study for inherited Parkinson’s using PET, SPECT, and spinal fluid
This trial tests how well special brain scans (PET/SPECT) and spinal fluid tests can show changes in people with inherited (genetic) Parkinson’s. It may help researchers understand what’s happening in the brain and improve how these conditions are measured.
Exeter, DevonAges 25–80 - NCT05539196Recruiting
Registry for Exablate treatment in Parkinson’s with medication problems
This trial is a real-world registry that follows people with Parkinson’s who are planning to get an Exablate 4000 procedure (a focused ultrasound treatment) for one-sided symptoms that are difficult to control with medication. It mainly checks outcomes and safety over time, helping doctors understand how well this treatment works in everyday care.
Baltimore, MarylandAges 30–99 - NCT05568498RecruitingPhase 2
Probiotic trial for depression in Parkinson’s disease
This Phase 2 study tests whether taking probiotics can improve depression and mood symptoms in people with Parkinson’s disease. It’s meant for those with mild to moderate depression and stable Parkinson’s and mood treatments.
Vancouver, British ColumbiaAges 40–80 - NCT05778617RecruitingPhase 3
Ambroxol to Slow Parkinson’s Disease Progression
This trial studies whether ambroxol (or a placebo) can slow the progression of Parkinson’s disease. It may help by aiming to change how the disease develops over time.
BirminghamAges 35–75 - NCT05800470Recruiting
Brain-training with light sensors to improve walking in Parkinson’s
This trial tests a “neurofeedback” training program using a special light-sensing cap (fNIRS) to help improve balance and walking in people with Parkinson’s disease. You may also do guided walking practice mentally (imagery training), and your ability to walk and balance will be measured.
Taipei, None SelectedAges 40–85 - NCT05820074Recruiting
Neural signals and walking changes in Parkinson’s patients
This study measures brain and nerve “biomarkers” to understand how Parkinson’s affects walking and balance. It may help researchers identify signs that relate to gait problems, and participants with a specific implanted stimulator may be able to take part in testing with stimulation turned off.
Vitznau, Canton of LucerneAges 18 years+ - NCT05864157Recruiting
Targeted training to improve walking in Parkinson’s disease
This study tests a targeted motor training approach to improve walking (gait) in people with Parkinson’s disease. You may be considered if your walking is affected but you can already walk steadily for 10 minutes without help.
Chapel Hill, North CarolinaAges 50–80 - NCT05884944Recruiting
Osteopathic massage study for leg muscle in Parkinson’s disease
This trial studies whether osteopathic manipulative medicine (gentle hands-on treatment) can change how leg muscles work in people with Parkinson’s disease. It may help with leg pain, cramping, or walking problems caused by Parkinson’s.
Old Westbury, New YorkAges 18 years+ - NCT05908279Recruiting
Walking and gait study in people with Parkinson’s disease
This trial studies walking patterns and how walking is controlled in people with Parkinson’s disease. It may help researchers understand movement control and improve future therapies by comparing walking ability and patterns.
Louvain-la-NeuveAges 18–99 - NCT05943652Recruiting
Study of how functional overlay affects movement disorders
This study looks at movement disorders that are functional (not caused by damage to the nervous system) or non-functional, and how a “functional overlay” may change symptoms. It is observational, meaning it does not test a new treatment, but it may help researchers better understand these differences and improve care.
Graz, StyriaAges 18–18 - NCT05962489Recruiting
Sleep-focused DBS therapy study for Parkinson’s disease
This study looks at a sleep-focused approach to brain stimulation (DBS) in people with Parkinson’s disease. You may be able to join if you’re planning or scheduled for specific DBS surgery at the University of Minnesota and have the needed brain imaging.
Minneapolis, MinnesotaAges 21 years+ - NCT05997043RecruitingEarly Phase 1
Botulinum toxin for overactive bladder in Parkinson's disease
This trial tests if botulinum toxin A injections can help control overactive bladder symptoms in people with Parkinson's disease who haven't gotten enough relief from standard bladder medications. It aims to see if the treatment is safe and effective.
Guangzhou, GuangdongAges 25–80 - NCT06129942Recruiting
Light therapy for Parkinson's disease
This trial tests whether regular light therapy can help people with Parkinson's disease. It is designed for patients whose symptoms are at a moderate stage and whose medication has been stable for a month or more.
Suzhou, JiangsuAges 50–80 - NCT06147999Recruiting
Biophoton therapy for brain disorders
This trial tests a biophoton therapy, a light-based treatment, for people with brain disorders. It aims to see if this non-invasive approach can help improve symptoms.
Butler, PennsylvaniaAges 18 years+ - NCT06174948Recruiting
CUE1 device for Parkinson's and related movement disorders
This trial tests a small device called CUE1 that gives gentle vibrations on the chest to help improve movement and balance in people with Parkinson's disease and similar conditions. It may help if you have trouble with walking or stability.
LondonAges 18 years+ - NCT06193252Recruiting
Exercising to slow Parkinson's in iRBD
This study tests whether a specific amount of exercise can slow the development of Parkinson's disease in people who have a sleep condition called iRBD. If you have iRBD and are not very active, researchers will help you start a personalized exercise program and track your progress with a smartphone app.
Nijmegen, GelderlandAges 50 years+ - NCT06203106Recruiting
NYSCF Scientific Discovery Biobank
This study collects blood, saliva, or skin samples from people with certain neurological conditions and from healthy volunteers to help researchers better understand and find treatments for these diseases.
New York, New YorkAges 4 weeks+ - NCT06237868Recruiting
TMS for Impulse Control in Parkinson's Disease
This trial tests whether a type of non-invasive brain stimulation called TMS can help reduce impulse control problems (like gambling or compulsive eating) that are caused by Parkinson's medications. It's for people with Parkinson's who are living with these side effects.
Morgantown, West VirginiaAges 18 years+ - NCT07695233Recruiting
Ultrasound brain stimulation for freezing of gait in Parkinson's
This trial tests a noninvasive ultrasound treatment targeting a brain area called the pedunculopontine nucleus to help reduce freezing of gait (a sudden inability to walk) in Parkinson's disease. If you have Parkinson's and experience freezing, you may be eligible to try this new approach.
Toronto, OntarioAges 18–90 - NCT06402955RecruitingPhase 2
Imaging depression in Parkinson's disease
This study uses brain imaging (PET scans) to understand depression in people with Parkinson's disease. It may also test a depression treatment called ketamine, but the main goal is to see how the brain changes with depression.
New Haven, ConnecticutAges 40–80 - NCT06485986Recruiting
Brain Networks in Parkinson's and DBS
This study uses a brain scan called MEG to look at how Parkinson's disease and impulse control disorders affect brain networks in people who have already had deep brain stimulation (DBS) surgery. You will be asked to delay your morning medication so the researchers can study your brain without the effects of the drugs.
OxfordAges 18 years+
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Common questions
- Are there clinical trials for parkinson disease (disorder)?
- Yes. Clin2 currently lists 497 recruiting parkinson disease (disorder) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson disease (disorder) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson disease (disorder) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.