Clinical trials
PARKINSON DISEASE (Disorder) clinical trials
Below are recruiting parkinson disease (disorder) clinical trials, each written for real people, not researchers. We’re tracking 496 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07229651RecruitingPhase 2/Phase 3
Metformin for Parkinson's disease
This trial tests if metformin, a diabetes drug, can help people with Parkinson's disease. It may improve symptoms or slow progression.
TantaAges 50–70 - NCT07226284Recruiting
Testing a nerve stimulation device for leg movement in Parkinson's
This study tests if a device that stimulates the vagus nerve (a nerve in your neck) can improve leg muscle activity and walking balance in people with Parkinson's disease. You would participate in experiments while wearing the device to see how it affects your movement.
Minneapolis, MinnesotaAges 21–76 - NCT06914466Recruiting
DBS for sleep problems in Parkinson's disease
This study looks at how deep brain stimulation (DBS) affects sleep problems in people with Parkinson's disease. It aims to understand brain changes and improve sleep quality.
Beijing, Beijing MunicipalityAges 19–80 - NCT07217054Recruiting
Parkinson's and RBD diagnosis via colon biopsy
This trial uses a small piece of colon tissue, taken during a routine colonoscopy, to look for a protein linked to Parkinson's disease and REM sleep behavior disorder (RBD). It aims to improve diagnosis for these conditions.
Branford, ConnecticutAges 40–99 - NCT07213232Enrolling by invitation
Balance and thinking training for Parkinson's
This study tests if combining balance and walking exercises with thinking tasks can improve movement and daily life in people with Parkinson's disease. It is for those in early to moderate stages who can participate in physical and cognitive training.
Ankara, ÜniversitelerAges 40 years+ - NCT07204652Recruiting
Colonoscopy test for Parkinson's disease detection
This study tests whether a protein in colon tissue can help diagnose Parkinson's disease. People with Parkinson's who already need a routine colonoscopy may participate.
Portland, OregonAges 40–99 - NCT04848077Recruiting
Smartphone exercise program for early Parkinson’s patients
This trial tests whether a motivating phone-based exercise plan can help people with early-stage Parkinson’s move more safely and consistently. You may qualify if you can walk on your own, understand Dutch, and are fairly inactive right now.
Nijmegen, GelderlandAges 18 years+ - NCT07187843Recruiting
Parkinson's type study: brain-first vs body-first
This study looks at how Parkinson's disease affects thinking, movement, and brain health differently depending on whether it starts in the brain or the body first. Participants will have tests and scans to track these differences over time.
Reggio EmiliaAges 18 years+ - NCT07190404Recruiting
Thinking skills program for Parkinson's disease
This study tests a program to help people with Parkinson's disease who are noticing problems with their memory or thinking. The program teaches strategies to manage daily thinking challenges.
St Louis, MissouriAges 50 years+ - NCT07182058RecruitingPhase 1/Phase 2
Brain stimulation device for Parkinson's motor symptoms
This trial tests a wearable brain stimulation device (tES) that delivers gentle electrical currents to your head to help improve Parkinson's motor symptoms like tremor, stiffness, or slowness. The treatment is done at home with remote video monitoring, and may offer a non-medication option to help with movement.
Cleveland, OhioAges 18–80 - NCT05778617RecruitingPhase 3
Ambroxol to Slow Parkinson’s Disease Progression
This trial studies whether ambroxol (or a placebo) can slow the progression of Parkinson’s disease. It may help by aiming to change how the disease develops over time.
BirminghamAges 35–75 - NCT07151378RecruitingPhase 3
Intestinal gel for Parkinson's mood and behavior problems
This trial tests a gel form of levodopa (called Lecigon) given through a tube into the intestine to see if it helps reduce mood swings, impulsive behaviors, and other mental side effects in people with Parkinson's who already have motor fluctuations. It is for people who have had Parkinson's for at least 5 years and are between 18 and 75 years old.
Saarlouis, SaarlandAges 18–75 - NCT07094269Recruiting
Fatigue management program for Parkinson's disease
This trial tests a structured fatigue management program compared to standard information to help people with Parkinson's disease better manage their energy. It aims to improve your confidence in using energy-saving strategies.
GenovaAges 18 years+ - NCT07056361Recruiting
Testing brain stimulation for better movement in tremor and Parkinson's
This study tests whether stimulating specific brain areas (VOP/VIM) during deep brain stimulation surgery can improve movement and muscle control. It includes people with essential tremor or Parkinson's disease who are already scheduled for this surgery.
Pittsburgh, PennsylvaniaAges 18–75 - NCT07056348Recruiting
Brain stimulation to improve movement in Parkinson's or tremor
This study tests brain stimulation in a region called VOP/VIM to see if it can improve motor function. It is for people with movement disorders who are already getting deep brain stimulation (DBS) surgery.
Pittsburgh, PennsylvaniaAges 18–80 - NCT07026734Recruiting
Speech and Swallow Effects of Deep Brain Stimulation in Parkinson's
This study looks at how deep brain stimulation (DBS) affects speech and swallowing in people with Parkinson's disease. It aims to help understand changes so doctors can better support you after DBS surgery.
Gainesville, FloridaAges 45–85 - NCT06993142Recruiting
Slowing Parkinson's Early With Exercise
This trial tests whether a specific exercise program can slow the early stages of Parkinson's disease in people who have a genetic risk (LRRK2 or GBA variants). You will use a smartphone app to guide your exercise from home.
Rochester, New YorkAges 50 years+ - NCT06965374Recruiting
Study of a new Parkinson's injection and quality of life
This study is looking at how a new continuous 24-hour injection treatment (foslevodopa/foscarbidopa) affects quality of life in people with advanced Parkinson's disease. It is a real-world study, meaning you just take the medication as your doctor prescribes, and researchers observe the results.
Troina, EnnaAges 18 years+ - NCT06588439Recruiting
Cognitive-motor training for Parkinson's
This study tests a type of training that combines thinking tasks with movement exercises to see if it can improve symptoms in people with Parkinson's disease.
TaipeiAges 40–80 - NCT06941012Recruiting
Measuring alpha-synuclein changes in Parkinson's disease progression
This study examines changes in alpha-synuclein, a protein linked to Parkinson's, to better understand how the disease progresses. It may help researchers learn more about Parkinson's and improve future care.
ThessalonikiAges 18–85 - NCT06918938Recruiting
Vision and movement study for Parkinson disease
This study looks at how Parkinson disease affects the connection between vision and movement. You will be asked to view a computer screen and perform simple tasks to help researchers understand these changes.
Taipei, Zhongzheng Dist.Ages 18 years+ - NCT06885138Enrolling by invitation
Testing brain stimulation for depression in Parkinson's disease
This trial tests if a gentle brain stimulation technique called tDCS can improve depression symptoms in people with Parkinson's disease. You'll receive either real or placebo stimulation over several sessions to see if it helps your mood.
MilanAges 35–75 - NCT06875739Enrolling by invitation
Saliva test for early diagnosis of brain diseases
This study tests whether a saliva sample can help tell the difference between brain diseases like Alzheimer's, Parkinson's, and related conditions. By using a special laser technique, researchers hope to find a quick, non-invasive way to make an earlier and more accurate diagnosis.
CagliariAges 60–85 - NCT06868160Recruiting
Brain stimulation to improve walking in Parkinson's disease
This study tests whether different types of gentle electrical stimulation on the scalp can help improve walking and balance problems in people with Parkinson's disease. The goal is to find a better way to support rehabilitation.
MilanAges 45–85
Hear when a new PARKINSON DISEASE (Disorder) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for parkinson disease (disorder)?
- Yes. Clin2 currently lists 496 recruiting parkinson disease (disorder) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson disease (disorder) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson disease (disorder) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.