Clinical trials
PARKINSON DISEASE (Disorder) clinical trials
Below are recruiting parkinson disease (disorder) clinical trials, each written for real people, not researchers. We’re tracking 496 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06841718Enrolling by invitation
Brain study of freezing in Parkinson's disease
This study uses brain imaging to understand why some people with Parkinson's suddenly feel like their feet are glued to the floor (freezing of gait). It may help find better treatments for this symptom.
LeuvenAges 18 years+ - NCT06705517Recruiting
Mediterranean diet study for Parkinson's disease
This trial tests whether a Mediterranean diet can help people with Parkinson's disease. You would either follow your usual diet or switch to a Mediterranean diet for six months and provide blood and stool samples.
Varese, VareseAges 40–85 - NCT06821230Recruiting
Mindfulness for Parkinson's patients and their caregivers
This study tests whether a dyadic mindfulness program can help both people with Parkinson's disease and their caregivers manage negative emotions. You and your care partner would attend sessions together to learn mindfulness techniques.
Hong KongAges 18 years+ - NCT05800470Recruiting
Brain-training with light sensors to improve walking in Parkinson’s
This trial tests a “neurofeedback” training program using a special light-sensing cap (fNIRS) to help improve balance and walking in people with Parkinson’s disease. You may also do guided walking practice mentally (imagery training), and your ability to walk and balance will be measured.
Taipei, None SelectedAges 40–85 - NCT06147999Recruiting
Biophoton therapy for brain disorders
This trial tests a biophoton therapy, a light-based treatment, for people with brain disorders. It aims to see if this non-invasive approach can help improve symptoms.
Butler, PennsylvaniaAges 18 years+ - NCT06679374RecruitingPhase 2
Can varenicline help reduce falls in Parkinson disease?
This phase 2 trial tests a medicine called varenicline (brand name Chantix) to see if it can reduce falls in people with Parkinson disease who also have a specific brain change (loss of a chemical called acetylcholine in the back of the brain) and mild cognitive problems. The study will help determine if this medicine is safe and effective for this group.
Ann Arbor, MichiganAges 45 years+ - NCT06642454Enrolling by invitation
Breathing-guided nerve stimulation for Parkinson's disease
This study tests a type of nerve stimulation (vagus nerve) for Parkinson's disease. It compares a method that uses your breathing cycle to deliver stimulation versus standard stimulation. The goal is to see which works better for movement and non-movement symptoms.
Hefei, AnhuiAges 40–80 - NCT06582121Recruiting
Sleep disorders in early and advanced Parkinson's disease
This study looks at sleep problems in people with Parkinson's disease, people with REM sleep behavior disorder (a condition that causes acting out dreams), and healthy volunteers. The goal is to understand how sleep is affected in early and full Parkinson's disease.
Clermont-FerrandAges 18 years+ - NCT06498349Recruiting
DBS for Parkinson's impulse control problems
This trial tests whether deep brain stimulation (DBS) of the subthalamic nucleus can help control impulse control problems (like gambling, overeating, or shopping) in people with Parkinson's disease. It is for patients whose medication-related impulse symptoms are moderate to severe and who are good candidates for DBS surgery.
CologneAges 18–70 - NCT06508801Recruiting
Blood flow restriction to improve balance in Parkinson's
This study tests whether gently restricting blood flow to your legs during exercise can help improve balance for people with Parkinson's disease. You will do simple leg exercises while wearing a special cuff, which may strengthen muscles and improve steadiness.
San Antonio, TexasAges 40–85 - NCT06402955RecruitingPhase 2
Imaging depression in Parkinson's disease
This study uses brain imaging (PET scans) to understand depression in people with Parkinson's disease. It may also test a depression treatment called ketamine, but the main goal is to see how the brain changes with depression.
New Haven, ConnecticutAges 40–80 - NCT06341829Enrolling by invitation
Vision and emotions in Parkinson's disease
This study explores how Parkinson's disease affects visual and emotional abilities. It aims to understand these challenges better to improve future care.
Messina, MessinaAges 18–90 - NCT05943652Recruiting
Study of how functional overlay affects movement disorders
This study looks at movement disorders that are functional (not caused by damage to the nervous system) or non-functional, and how a “functional overlay” may change symptoms. It is observational, meaning it does not test a new treatment, but it may help researchers better understand these differences and improve care.
Graz, StyriaAges 18–18 - NCT06237868Recruiting
TMS for Impulse Control in Parkinson's Disease
This trial tests whether a type of non-invasive brain stimulation called TMS can help reduce impulse control problems (like gambling or compulsive eating) that are caused by Parkinson's medications. It's for people with Parkinson's who are living with these side effects.
Morgantown, West VirginiaAges 18 years+ - NCT06193252Recruiting
Exercising to slow Parkinson's in iRBD
This study tests whether a specific amount of exercise can slow the development of Parkinson's disease in people who have a sleep condition called iRBD. If you have iRBD and are not very active, researchers will help you start a personalized exercise program and track your progress with a smartphone app.
Nijmegen, GelderlandAges 50 years+ - NCT05205291Recruiting
Imaging inflammation in Parkinson’s using PET/MR scans
This study uses special brain scans (PET/MR) to see inflammation in people with Parkinson’s disease or related conditions. It may help researchers better understand what drives symptoms and how inflammation changes in the brain.
ExeterAges 50–85 - NCT05516732Recruiting
Testing serotonin activity in the brain in people with Parkinson’s
This study uses special scans to measure how serotonin is released in parts of the brain involved in movement in Parkinson’s disease. It may help researchers understand disease changes and the role of serotonin systems in movement problems.
Exeter, DevonAges 25–85 - NCT05516719Recruiting
Study tracking I2BS in Parkinson’s over time
This study follows people with Parkinson’s to see how “I2BS” changes over time using special brain scans and other tests. It may help researchers better understand Parkinson’s and improve how it’s measured in future trials.
Exeter, DevonAges 25 years+ - NCT05518617Recruiting
Imaging study for inherited Parkinson’s using PET, SPECT, and spinal fluid
This trial tests how well special brain scans (PET/SPECT) and spinal fluid tests can show changes in people with inherited (genetic) Parkinson’s. It may help researchers understand what’s happening in the brain and improve how these conditions are measured.
Exeter, DevonAges 25–80 - NCT06088355Recruiting
Comparing exercise amounts for moderate Parkinson's
This study compares two different amounts of light-to-moderate exercise to see which is better for people with moderate Parkinson's disease. It involves walking or doing similar activities at a comfortable pace, either a moderate amount or a higher volume, over several weeks.
Decatur, GeorgiaAges 40 years+ - NCT06084533Enrolling by invitation
Brain inflammation imaging in Parkinson's disease
This study uses a special PET scan to look for signs of brain inflammation in people with Parkinson's disease. It aims to understand how inflammation relates to Parkinson's and may help in developing new treatments.
St Louis, MissouriAges 50 years+ - NCT05962489Recruiting
Sleep-focused DBS therapy study for Parkinson’s disease
This study looks at a sleep-focused approach to brain stimulation (DBS) in people with Parkinson’s disease. You may be able to join if you’re planning or scheduled for specific DBS surgery at the University of Minnesota and have the needed brain imaging.
Minneapolis, MinnesotaAges 21 years+ - NCT05864157Recruiting
Targeted training to improve walking in Parkinson’s disease
This study tests a targeted motor training approach to improve walking (gait) in people with Parkinson’s disease. You may be considered if your walking is affected but you can already walk steadily for 10 minutes without help.
Chapel Hill, North CarolinaAges 50–80 - NCT04735458Recruiting
Brain network study for Parkinson’s or essential tremor
This study looks at how “inhibitory control” brain networks work in people with Parkinson’s disease or essential tremor. If you are eligible for surgery and can do the study tasks, your results may help researchers better understand movement disorders and guide future treatments.
Birmingham, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for parkinson disease (disorder)?
- Yes. Clin2 currently lists 496 recruiting parkinson disease (disorder) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson disease (disorder) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson disease (disorder) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.