Clinical trials
Parkinsonism clinical trials
Below are recruiting parkinsonism clinical trials, each written for real people, not researchers. We’re tracking 735 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06576713Recruiting
Genome and RNA sequencing for genetic diagnosis of early Parkinsonism
This study uses advanced genetic testing (genome and RNA sequencing) to find the genetic causes of Parkinsonism that starts before age 40 or runs in families. If you join, you will provide a blood sample and a small skin biopsy to help researchers understand your condition better.
Strasbourg, Grand EstAges 18 years+ - NCT06582212Recruiting
Managing Hormonal Triggers in Women with Parkinson's
This study helps women with Parkinson's disease who are still having periods learn how hormonal changes may affect their symptoms. You will be guided to identify and manage these triggers better.
GrenobleAges 18–56 - NCT06581523Recruiting
Breathing and meditation for Parkinson's wellness
This trial tests a breathing and meditation practice called SKY to see if it helps people with early-stage Parkinson's and their care partners feel better. You and your care partner will practice daily at home using Zoom.
Coral Springs, FloridaAges 18–75 - NCT06582121Recruiting
Sleep disorders in early and advanced Parkinson's disease
This study looks at sleep problems in people with Parkinson's disease, people with REM sleep behavior disorder (a condition that causes acting out dreams), and healthy volunteers. The goal is to understand how sleep is affected in early and full Parkinson's disease.
Clermont-FerrandAges 18 years+ - NCT06562569Recruiting
Non-invasive vagus nerve stimulation for Parkinson's gait issues
This study tests a non-invasive vagus nerve stimulation device to see if it can improve walking and reduce freezing of gait in people with Parkinson's disease. It is done at VA hospitals and involves wearing a device on the neck during walking tasks.
Hines, IllinoisAges 50–88 - NCT06565195RecruitingPhase 1
Study of an investigational drug for Parkinson's disease
This study tests an experimental drug called LY3962681 in two groups: healthy volunteers and people with Parkinson's disease. The goal is to see if the drug is safe and how the body handles it, which may lead to future treatments for Parkinson's.
Englewood, ColoradoAges 30–80 - NCT06561919Recruiting
Speech and language study during brain stimulation treatment
This is an extra part of the STIMPulseControl study that focuses on speech. It looks at how the brain stimulation treatment affects your ability to speak clearly and communicate.
CologneAges 18–70 - NCT06518824Recruiting
Theta brain stimulation to boost thinking in Parkinson's
This study tests whether a special pattern of deep brain stimulation (called theta bursts) can improve thinking and memory in people with Parkinson's disease. It's for patients who already have a DBS device in their brain that is at least 3 months old.
Vancouver, British ColumbiaAges 18–80 - NCT06506058Recruiting
Study on balance and brain in Parkinson's freezing of gait
This study looks at how the balance system and brain work together to cause freezing of gait in Parkinson's disease. By understanding these factors, researchers hope to find better ways to help people walk more steadily.
Minneapolis, MinnesotaAges 21–80 - NCT06482268RecruitingPhase 1
Cell transplant for advanced parkinson's disease
This trial tests a new type of cell transplant for Parkinson's disease. The cells are made from stem cells and are meant to replace damaged brain cells that produce dopamine, which may improve your motor symptoms.
La Jolla, CaliforniaAges 40–75 - NCT06466525RecruitingPhase 1
Testing LBT-3627 for safety in healthy adults and people with Parkinson's
This study tests an investigational drug called LBT-3627 to see if it is safe and how the body processes it. It includes healthy volunteers and people with Parkinson's disease, and may help determine if the drug could be a future treatment.
Melbourne, VictoriaAges 30–89 - NCT06464029Recruiting
Balance and walking study in Parkinson's disease
This study looks at balance problems in people with Parkinson's disease. It uses simple tests to understand what causes trouble with standing and walking, which may help find better treatments.
Minneapolis, MinnesotaAges 45–80 - NCT06467695Recruiting
Low voltage brain stimulation for depression in Parkinson's
This study tests whether a gentle, low-voltage electrical stimulation (tDCS) can help improve depression in people with Parkinson's disease. It involves coming to the lab for sessions where a small device sends a mild current to your brain, and you'll also have an EEG (a non-invasive brain wave recording).
Mobile, AlabamaAges 19–65 - NCT06442033Recruiting
Exercise and genetics to slow Parkinson's
This trial studies whether a regular aerobic cycling program can slow the progression of Parkinson's disease. Researchers will also look at how genetics may affect the benefits of exercise.
Cleveland, OhioAges 18 years+ - NCT06455293RecruitingPhase 2
Psilocybin therapy for depression in Parkinson's disease
This study tests whether psilocybin, a substance found in certain mushrooms, can help improve depression in people with Parkinson's disease. If you have Parkinson's and are feeling depressed, this treatment may offer a new option.
San Francisco, CaliforniaAges 40–80 - NCT06422208Enrolling by invitationPhase 1
Parkinson's cell transplant trial using your own cells
This trial tests whether transplanting special dopamine-producing cells made from a patient's own skin cells can help treat Parkinson's disease. It is for people who have had Parkinson's for at least 5 years and still respond well to medication.
Boston, MassachusettsAges 55–80 - NCT06425731Recruiting
Dance and energy in Parkinson's disease
This study looks at how dancing affects energy use in people with Parkinson's. If you already take Dance for PD® classes and have mild to moderate Parkinson's, researchers want to see how your body responds during a dance class.
Boston, MassachusettsAges 18–85 - NCT06405334Recruiting
Balance and movement study for veterans with Parkinson's
This study looks at how Parkinson's disease affects balance and movement. It may help predict fall risk and improve care. Some participants also have a special brain device to help with movement.
Minneapolis, MinnesotaAges 18 years+ - NCT06416345Recruiting
Cue2Walk: Freezing detection and cues for Parkinson's walking
This study tests whether a new device called Cue2Walk can help people with Parkinson's disease who have freezing of gait. The device detects when you freeze and sends a signal (like a beep) to help you start walking again. Researchers want to see if it is worth the cost compared to your usual care.
Nijmegen, GelderlandAges Any age - NCT06402955RecruitingPhase 2
Imaging depression in Parkinson's disease
This study uses brain imaging (PET scans) to understand depression in people with Parkinson's disease. It may also test a depression treatment called ketamine, but the main goal is to see how the brain changes with depression.
New Haven, ConnecticutAges 40–80 - NCT06386497Recruiting
Bed for better sleep in Parkinson's disease
This study tests a special bed (Somnomat Casa) to help improve sleep in people with Parkinson's disease. It looks at whether the bed is comfortable and acceptable to use.
BernAges 18–85 - NCT06385184Recruiting
Social life and quality of life in Parkinson's
This study looks at how social life and quality of life are affected in Parkinson's disease. It compares people with Parkinson's to those without to better understand these changes.
Washington D.C., District of ColumbiaAges 40 years+ - NCT04724941Recruiting
Screening for alpha-synuclein in early Parkinson’s risk
This study looks for changes in a protein called alpha-synuclein in people who may be in the early “prodromal” stage before Parkinson’s symptoms fully appear. It may help researchers find early markers and understand who is more likely to develop Parkinson’s disease.
KielAges 50–99 - NCT06339398Recruiting
Exercise dose and brain health in Parkinson's
This study looks at how different amounts of physical exercise affect brain chemicals, movement symptoms, and brain connections in people with Parkinson's disease. You would walk and do exercises while researchers track changes over time.
Cassino, FrosinoneAges 30–80
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Common questions
- Are there clinical trials for parkinsonism?
- Yes. Clin2 currently lists 735 recruiting parkinsonism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinsonism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinsonism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.