Clinical trials
Parkinsonism clinical trials
Below are recruiting parkinsonism clinical trials, each written for real people, not researchers. We’re tracking 750 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02763683Recruiting
Study brain changes in Parkinson-related dementia
This study looks at brain features linked to dementia in people who have Parkinson disease. It may help researchers understand why dementia happens in Parkinson and how it could be detected or treated in the future.
St Louis, MissouriAges 50 years+ - NCT01989013Enrolling by invitation
CranioSacral therapy for people with Parkinson’s disease
This study looks at whether a hands-on therapy called CranioSacral Integrated Therapy can improve symptoms in people with Parkinson’s disease. If you have Parkinson’s, the goal is to see whether this treatment changes how you feel or function.
Ann Arbor, MichiganAges 18 years+ - NCT07398157Recruiting
24-hour adaptive deep brain stimulation for Parkinson's
This trial tests a new deep brain stimulation system that adapts in real time to improve symptom control over 24 hours, especially for people with daytime fluctuations or sleep problems despite standard DBS.
San Francisco, CaliforniaAges 18 years+ - NCT07403539Recruiting
Speech learning and production in Parkinson's disease
This study looks at how people with Parkinson's disease learn and produce speech. It may help researchers understand how Parkinson's affects talking and how to improve communication.
Buffalo, New YorkAges 45 years+ - NCT07404241Recruiting
Brain activity linked to movement and mood swings in Parkinson's
This study looks at brain signals related to motor and psychiatric changes in people with Parkinson's who are scheduled for deep brain stimulation (DBS) surgery. The goal is to better understand why symptoms fluctuate and how DBS may help.
GenevaAges 18–80 - NCT07409207Recruiting
Brain signals and reward in Parkinson's surgery
This study looks at brain activity related to reward during deep brain stimulation (DBS) surgery to help us understand Parkinson's disease better. If you are having DBS surgery, your brain signals during the procedure may help researchers.
Nashville, TennesseeAges 40 years+ - NCT07424924Recruiting
Walking, activity, and sleep study for Parkinson's
This study looks at how walking, daily activity, and sleep are connected in Parkinson's disease. It compares people with Parkinson's to healthy volunteers to understand these links better.
IstanbulAges 40–75 - NCT07434089Recruiting
Walking therapy and gut health in Parkinson's
This trial tests how a special treadmill (C-Mill) training affects the connection between your brain and gut in Parkinson's disease. It may help improve walking and gut symptoms.
Messina, MessinaAges 40–70 - NCT07441915Recruiting
Sleep Sounds and Brain Training for Parkinson's with Mild Memory Problems
This trial tests whether playing soft sounds during sleep can boost the effects of a computer-based brain training program in people with Parkinson's disease who have mild memory or thinking issues. If you qualify, you'll use a headband that plays tones while you sleep and do brain exercises for several weeks.
Zurich, Canton of ZurichAges 18 years+ - NCT07457710Recruiting
Remote haptic rehab for Parkinson's disease
This study tests a remote therapy program that uses gentle vibrations (haptic feedback) to help people with Parkinson's disease improve their movement and coordination. You can participate from home, as long as you have mild to moderate Parkinson's.
Blacksburg, VirginiaAges 18 years+ - NCT07461220RecruitingPhase 1/Phase 2
Testing IRL757 for apathy in Parkinson's disease
This trial tests a new drug called IRL757 to see if it is safe and helps with apathy (loss of motivation or interest) in people with Parkinson's disease. You need to have at least moderate apathy and a caregiver who can come to visits with you.
PlevenAges 50–90 - NCT07465107Recruiting
Motor and cognitive exercise in Parkinson's
This study tests whether combining motor (physical movement) exercises with cognitive (thinking) exercises can help people with Parkinson's disease. It may improve both movement and thinking skills.
Copenhagen NVAges 18 years+ - NCT07467460Recruiting
Precision medicine trial for Parkinson's and Alzheimer's
This trial uses advanced tools to better diagnose and treat Parkinson's disease and Alzheimer's disease. It aims to personalize care based on your specific symptoms and biomarkers.
PozzilliAges 18 years+ - NCT07475741Recruiting
Exergaming for better arm and hand function in Parkinson's
This trial tests whether exergaming (video games that involve physical movement) can improve arm and hand function in people with early-stage Parkinson's disease. It may help you move better and do daily tasks more easily.
Lahore, Punjab ProvinceAges 45–85 - NCT07478146Recruiting
Aerobic exercise for brain and movement in Parkinson's
This study tests whether moderate aerobic exercise (like brisk walking or cycling) can improve thinking, memory, and walking ability in people with Parkinson's disease. It also looks at how exercise affects blood flow in the brain.
São Paulo, São PauloAges 40 years+ - NCT07485621Recruiting
Using brain signals to improve deep brain stimulation for Parkinson's
This study uses brain signals (called local field potentials) from the deep brain stimulation (DBS) device to see if they can predict how well the treatment is working. It aims to help doctors adjust DBS settings more precisely for people with Parkinson's disease.
Leuven, Vlaams-BrabantAges 18 years+ - NCT06671600Recruiting
Osteopathic treatment for sleep in Parkinson's disease
This study tests if gentle hands-on treatments (osteopathic manipulative medicine) can improve sleep quality for people with Parkinson's disease. You will wear a Fitbit and a ring to track your sleep, and receive the treatments over several sessions.
Old Westbury, New YorkAges Any age - NCT06285643RecruitingPhase 2
Gene therapy for moderate Parkinson's disease
This trial tests a gene therapy (AAV2-GDNF) to see if it can slow or improve symptoms of Parkinson's disease. It is for people who have had moderate Parkinson's for 4 to 10 years and still respond to levodopa therapy.
Phoenix, ArizonaAges 45–75 - NCT07488026Recruiting
Brain stimulation for mobility in Parkinson's disease
This trial tests if a type of brain stimulation (transcranial magnetic stimulation) applied to different areas of the brain can improve walking and movement in people with Parkinson's disease. The goal is to see which stimulation site works best for reducing freezing of gait and improving daily mobility.
Recife, PernambucoAges 40 years+ - NCT07498296Recruiting
Adapting a home program and sleep tracking for Parkinson's
This trial tests a program to help people with Parkinson's disease exercise at home and improve sleep. It uses online coaching and a video device to see if it makes daily tasks easier.
Aurora, ColoradoAges 18 years+ - NCT07518290Recruiting
Home brain stimulation for Parkinson's disease movement symptoms
This trial tests a non-invasive brain stimulation technique called transcranial temporal interference stimulation (TTIS) that you can use at home with remote supervision. It aims to improve movement problems like stiffness, tremor, and slowness in people with mild-to-moderate Parkinson's disease.
Shanghai, Shanghai MunicipalityAges 40–80 - NCT07523425Recruiting
Virtual Reality Movement Training for Parkinson's Disease
This study tests whether using virtual reality—either alone or with others—can help improve movement and balance in people with Parkinson's disease. You would participate in rehabilitation sessions using VR technology while your symptoms and mobility are monitored.
Lahore, Punjab ProvinceAges 45–80 - NCT07524400Recruiting
Exercise Plus Brain Stimulation for Parkinson's Disease
This study tests whether combining physical exercise with transcranial direct current stimulation (a non-invasive electrical stimulation of the brain) can improve movement and symptoms in people with Parkinson's disease. The goal is to see if this combination works better than exercise alone.
Fuenlabrada, MadridAges Any age - NCT07536022Recruiting
At-Home Ear Stimulation for Walking and Balance in Parkinson's
This study tests a small device worn on your ear (called taVNS) that sends mild electrical signals to help improve walking and balance problems in Parkinson's disease. You'll use it at home, and researchers will track whether it helps you move better.
Charleston, South CarolinaAges 40–85
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Common questions
- Are there clinical trials for parkinsonism?
- Yes. Clin2 currently lists 750 recruiting parkinsonism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinsonism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinsonism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.