Clinical trials
Parkinsonism clinical trials
Below are recruiting parkinsonism clinical trials, each written for real people, not researchers. We’re tracking 735 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05901818RecruitingPhase 1
Testing a patient’s own stem-cell treatment for Parkinson’s
This Phase 1 study tests whether an “autologous” (from your own body) iNSC-DAP stem-cell treatment is safe and may help symptoms in Parkinson’s disease. It is designed mainly to check safety, while also watching for signs of improvement.
Beijing, Beijing MunicipalityAges 30–85 - NCT05897957Enrolling by invitation
Follow-up study for people who received BRT-DA01
This study is for people with Parkinson’s disease who previously took part in an earlier BRT-DA01 trial and finished it (or stopped it). It mainly checks how participants do over time after that earlier treatment.
Orange, CaliforniaAges 50–78 - NCT05864157Recruiting
Targeted training to improve walking in Parkinson’s disease
This study tests a targeted motor training approach to improve walking (gait) in people with Parkinson’s disease. You may be considered if your walking is affected but you can already walk steadily for 10 minutes without help.
Chapel Hill, North CarolinaAges 50–80 - NCT05626608Recruiting
Directional brain stimulation for Parkinson’s tremor and movement control
This trial tests a continuous electrical brain stimulation device placed in a deep brain area to help Parkinson’s symptoms—especially tremor and trouble with movement. It may help improve daily function and reduce periods when medicine does not work well.
Montpellier, FranceAges 18–70 - NCT05818189Recruiting
Study walking brain signals in Parkinson’s with medication and cues
This study measures brain activity while you walk using a noninvasive light sensor setup. Researchers want to see how Parkinson’s medication and simple “walking cues” change balance and brain signals.
Portland, OregonAges 45–85 - NCT05779475Enrolling by invitation
Study of people with moderate Parkinson’s disease
This is an observational study, meaning it doesn’t test a new drug—researchers mainly follow people to better understand moderate Parkinson’s disease and who may be good candidates for future cell therapy. If you have moderate symptoms that aren’t well controlled with tablets, this study may help inform better future treatments.
Irvine, CaliforniaAges 50–68 - NCT05765110Recruiting
Tracking speech, movement, and thinking in Parkinson’s disease
This study looks at how people with Parkinson’s disease speak, move, and think to see whether these patterns can act like a “biomarker” (a measurable sign) of the disease. It also involves healthy volunteers to compare results.
PragueAges 30–75 - NCT05680597Recruiting
Video balance rehab program for Parkinson’s symptoms
This trial tests a 4-week, at-home video rehabilitation program focused on balance problems in people with Parkinson’s disease. It aims to see whether this tele-rehab approach helps with walking and stability while keeping medications steady.
Portland, OregonAges 55–85 - NCT05700825RecruitingPhase 2
Rehab training to improve swallow safety in Parkinson’s
This trial tests a rehabilitation approach aimed at improving airway protection during swallowing in people with Parkinson’s disease. It may help reduce the risk of food or liquid going down the wrong way by improving swallow safety.
West Lafayette, IndianaAges 50–90 - NCT05658302Recruiting
Deep brain stimulation for Parkinson’s, using targeted stimulation
This study is testing a specific approach to deep brain stimulation (DBS) for people with Parkinson’s disease who are getting DBS surgery as part of routine care. It may help doctors learn whether circuit-based, more targeted stimulation is safe and useful for Parkinson’s symptoms.
Minneapolis, MinnesotaAges 21 years+ - NCT05644327Recruiting
Exercise program to improve sleep in Parkinson’s disease
This study looks at whether an exercise program can improve sleep problems in people with Parkinson’s disease. It’s mainly for those who already have poor sleep quality while taking stable Parkinson’s medicine.
Laval, QuebecAges 40 years+ - NCT05603715RecruitingPhase 2
Pyridostigmine to help constipation in Parkinson’s
This trial tests whether pyridostigmine can improve constipation symptoms in people with Parkinson’s disease. If you have Parkinson’s and functional constipation (with infrequent bowel movements), this study may offer a new medication option and closely track your bowel function.
Burlington, VermontAges 18 years+ - NCT05557864Recruiting
Brain scan study for Parkinson’s patients with deep brain stimulators
This study looks at how the location of a deep brain stimulator in Parkinson’s disease affects movement problems. It mainly uses advanced 7T brain imaging to compare brain activity and motor symptoms.
Minneapolis, MinnesotaAges 21–89 - NCT05573542Enrolling by invitation
Study early Parkinson signs in people with IBS
This study looks for early clues of Parkinson’s disease in people who have IBS (irritable bowel syndrome), and compares them with people without IBS. The goal is to understand whether gut symptoms or test results can help spot Parkinson’s earlier.
ÖrebroAges 18–85 - NCT05539196Recruiting
Registry for Exablate treatment in Parkinson’s with medication problems
This trial is a real-world registry that follows people with Parkinson’s who are planning to get an Exablate 4000 procedure (a focused ultrasound treatment) for one-sided symptoms that are difficult to control with medication. It mainly checks outcomes and safety over time, helping doctors understand how well this treatment works in everyday care.
Baltimore, MarylandAges 30–99 - NCT05504902Enrolling by invitation
Device training for advanced Parkinson’s using touch feedback
This study tests whether coordinated touch (vibrotactile) training can improve symptoms in people with Parkinson’s. You may be asked to use a special device and attend virtual check-ins, with some visits requiring stopping Parkinson’s meds for short periods.
Stanford, CaliforniaAges 18 years+ - NCT05505019Recruiting
Using music to reduce apathy in Parkinson’s disease
This study tests whether music can help reduce apathy (low motivation) in people with Parkinson’s disease. It may help your mood and daily drive by targeting brain and behavior pathways tied to apathy.
Vancouver, British ColumbiaAges 40–85 - NCT05400499Recruiting
Deep brain stimulation study in Parkinson’s visuomotor function
This trial studies how deep brain stimulation affects hand-eye (visuomotor) coordination in people with Parkinson’s. It may help researchers understand whether the stimulation settings change movement control for daily tasks.
Cleveland, OhioAges Any age - NCT05357612RecruitingPhase 4
PET scan study for brain serotonin in neurodegenerative diseases
This study uses a special PET brain scan tracer to better understand serotonin receptor activity in people with certain neurodegenerative conditions, especially when they develop hallucinations or delusions. The results may help researchers improve how these brain changes are measured and tracked over time.
Nashville, TennesseeAges 50–85 - NCT05347407Recruiting
Gut nerve cell biomarkers study for Parkinson’s risk
This trial studies nerve cell “biomarkers” from the gut to learn whether they can help detect Parkinson’s disease (or related conditions) earlier. You may be asked to undergo a colonoscopy to collect gut tissue for testing.
New York, New YorkAges 45–75 - NCT05268887Recruiting
Light, sound, and touch therapy for Parkinson’s symptoms
This trial tests whether high-frequency light, sound, and gentle touch can improve movement and thinking problems in people with Parkinson’s disease. You may help the researchers learn if this kind of stimulation is safe and beneficial alongside your usual Parkinson’s medications.
Cambridge, MassachusettsAges 45–90 - NCT05266417RecruitingPhase 2
Nasal insulin plus glutathione for Parkinson’s symptoms
This Phase 2 study tests whether adding nasal insulin and glutathione can improve Parkinson’s disease symptoms and function. You would use study medicine through the nose while keeping your other treatments mostly the same during the trial.
Davie, FloridaAges 30 years+ - NCT05166655Enrolling by invitation
Recording brain signals during deep brain stimulation for Parkinson’s
This study uses special recordings during deep brain stimulation surgery to better understand how movement gets easier in Parkinson’s disease. It may help researchers improve how this therapy is used for advanced symptoms.
Los Angeles, CaliforniaAges 18 years+ - NCT05065151Recruiting
Studying motivation in Parkinson’s using brain stimulation recordings
This study looks at what drives motivation in people with Parkinson’s disease (or dystonia) by using recordings from an implanted brain stimulation device. It may help researchers understand brain signals behind motivation and improve future treatments.
San Francisco, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for parkinsonism?
- Yes. Clin2 currently lists 735 recruiting parkinsonism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinsonism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinsonism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.