Clinical trials
Patellofemoral Pain Syndrome clinical trials
Below are recruiting patellofemoral pain syndrome clinical trials, each written for real people, not researchers. We’re tracking 22 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07854041Recruiting
Release techniques for kneecap pain
This study tests two hands-on therapies to ease kneecap pain. It may help if your pain has lasted at least three months and gets worse with stairs, running, or sitting for a long time.
Lahore, Punjab ProvinceAges 15–40 - NCT07831200Recruiting
Taping and leg strengthening for knee pain
This study compares two types of tape (McConnell and Kinesio) combined with exercises to strengthen the hip and knee, to see which works better for people with pain in the front of the knee, especially when squatting or climbing stairs.
Islamabad, Punjab ProvinceAges 26–44 - NCT07734051Enrolling by invitation
Mobilization for kneecap pain
This trial tests if adding a groin-area mobilization to foot mobilization helps with kneecap (patellofemoral) pain. It may be for you if you have one-sided kneecap pain for at least 3 months, especially when climbing stairs, squatting, or sitting for long periods.
Fāqūs, SharkeyaAges 18–40 - NCT07693634Recruiting
Online rehab for knee pain in active adults
This study tests a home-based tele-rehabilitation program for people with front knee pain (patellofemoral pain syndrome) who are recreational athletes. It aims to see if online guided exercises can reduce pain and improve function.
Faisalābad, PunjanAges 18–35 - NCT06502795Recruiting
Quad Strengthening for Knee Pain at Different Angles
This study tests whether strengthening your quadriceps (front thigh muscles) at different knee angles can reduce pain behind or around your kneecap. If you have had this type of knee pain for at least 3 months, you may be eligible.
Fortaleza, CearáAges 18–35 - NCT06674707Recruiting
Agility training with foot exercises for kneecap pain
This trial tests whether adding foot exercises to agility training can better relieve long-lasting knee pain (patellofemoral pain syndrome) in adults ages 20 to 40. Eligible participants will have had pain behind the kneecap for over 6 months.
Lahore, Punjab ProvinceAges 20–40 - NCT07671482Recruiting
Kinesio vs McConnell taping for knee pain relief
This study compares two types of taping (Kinesio and McConnell) to see which works better for people with pain behind the kneecap (patellofemoral pain syndrome). You may help researchers learn how to best relieve knee pain during daily activities.
Beirut, BeirutAges 18–50 - NCT07585305Recruiting
Blood Flow Restriction Training for Knee Pain in Athletes
This study compares two types of exercise—resistance training and cycling—both using a special technique that temporarily reduces blood flow to your leg muscles. The goal is to see which approach works better for reducing knee pain and improving strength in athletes with patellofemoral pain (pain around or behind the kneecap).
IslamabadAges 18–40 - NCT07562425Recruiting
Knee Strengthening Exercises for Patellofemoral Pain
This study compares three types of thigh muscle exercises to help reduce knee pain in people with patellofemoral pain syndrome (pain around the kneecap). Researchers want to see which exercise style—holding steady, moving through motion, or lowering slowly—works best for your pain.
Elâzığ, MErkezAges 18–50 - NCT06758050Recruiting
Core exercises for front knee pain
This study tests whether doing core exercises can help reduce knee pain in people with patellofemoral pain syndrome—pain at the front of the knee that comes on gradually. It is meant for young adults with a healthy weight who have had this type of knee pain for more than 3 months.
GizaAges 18–35 - NCT06598618Recruiting
Comparing two therapies for kneecap pain
This study compares two types of hands-on treatments—Instrument-Assisted Soft Tissue Mobilization (IASTM) and Muscle Energy Technique—to see which works better for kneecap pain. It aims to find a therapy that can help reduce your pain and improve movement.
Rawalpindi, Punjab ProvinceAges 18–35 - NCT07318987Recruiting
Nerve release surgery for knee pain relief
This study tests if surgically releasing a nerve in the knee (the saphenous nerve) can reduce pain in people with patellofemoral pain syndrome (pain around the kneecap). If you've had anterior knee pain for at least six weeks and the nerve test is positive, this trial may offer relief.
CairoAges 18–35 - NCT06875804Recruiting
Compressive release for knee cap tracking in knee pain
This trial tests a hands-on therapy called compressive myofascial release for the muscle on the outside of your thigh. It aims to see if it helps with kneecap tracking problems that cause pain during daily activities.
Lahore, Punjab ProvinceAges 20–40 - NCT06517056Recruiting
3D Knee Assessment for Active Duty Knee Pain
This trial tests a 3D camera device that measures how your knee moves. It may help find the best way to treat your front-of-knee pain and keep you mission-ready.
Honolulu, HawaiiAges 18–50 - NCT05561153Enrolling by invitation
Study of knee movement issues in patellofemoral pain
This study looks at how the nerves and muscles are working in people with patellofemoral pain (pain around the kneecap). It may help researchers understand what drives the pain and how it might be treated.
AnkaraAges 18–40 - NCT03184545RecruitingPhase 3
Electrical stimulation vs physical therapy for knee pain
This trial compares an electrical stimulation treatment to standard physical therapy for people with long-lasting pain in the front of the knee. It aims to see which approach better improves symptoms and function for patellofemoral pain syndrome.
New York, New YorkAges 18–40 - NCT02890485Recruiting
Dry needling for knee pain with stair or squat pain
This study tests whether dry needling can reduce ongoing knee pain in people who feel pain around the kneecap when going up or down stairs, squatting, or running. You may be able to join if your knee pain has lasted at least 3 months and you’re referred to physical therapy.
Columbus, OhioAges 18–40 - NCT06736756Recruiting
Stretching hip muscle to help with knee pain
This trial tests if stretching the tensor fascia lata muscle (near your hip) changes how the muscle on the inside of your kneecap works. It is for people who have front knee pain without a specific injury, especially when doing things like running, squatting, or climbing stairs.
CairoAges 18–30 - NCT07290296Recruiting
Comparing muscle release and taping for knee pain
This trial compares two treatments for kneecap pain that has lasted at least 3 months: a muscle release technique and kinesio taping. The goal is to see which one helps reduce pain from daily activities like climbing stairs, running, or sitting for long periods.
CairoAges 18–30 - NCT06566950Recruiting
Blood flow training for leg muscle health in athletes
This study tests a training method that uses light blood flow restriction to improve leg muscle structure. It is for young athletes (ages 15–35) who play high-level sports like martial arts, basketball, soccer, or futsal at least twice a week.
Denpasar, BaliAges 15–35 - NCT00051857Recruiting
MRI Study of Muscle and Bone Function
This research study uses MRI scans (a safe imaging tool) to understand how bones, muscles, and joints work. Researchers are looking for both people with muscle or bone injuries and healthy volunteers to compare how the body moves and functions.
Bethesda, MarylandAges 5–95 - NCT06744257Recruiting
Online education for kneecap pain while waiting for physio
This trial tests whether an online education program is helpful for people with kneecap pain who are waiting for in-person physiotherapy. It aims to see if this approach is practical and beneficial.
ColchesterAges 16–44
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Common questions
- Are there clinical trials for patellofemoral pain syndrome?
- Yes. Clin2 currently lists 22 recruiting patellofemoral pain syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a patellofemoral pain syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a patellofemoral pain syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.