Clinical trials
Patient Controlled Analgesia clinical trials
Below are recruiting patient controlled analgesia clinical trials, each written for real people, not researchers. We’re tracking 55 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07657390RecruitingPhase 1/Phase 2
Acupoint plaster for moderate to severe cancer pain
This study tests a special pain-relief plaster placed on acupoints (body points used in acupuncture) to see if it can help people with moderate to severe cancer pain who are already taking pain medications. The goal is to find a gentler way to improve pain control.
BeijingAges 18 years+ - NCT06566482RecruitingPhase 4
Medicine for pain after surgery in sleep apnea patients
This trial tests a combination of two medicines (dexmedetomidine and esketamine) given in small doses to help with pain after surgery. It is for people who have sleep apnea or are at risk for it, and who are having chest or belly surgery with a scope.
Beijing, Beijing MunicipalityAges 18–80 - NCT07045870Recruiting
Pain relief methods after thyroid surgery
This study compares different ways to manage pain after thyroid removal surgery. It aims to find which method works best for recovery.
SohagAges 18–75 - NCT06869967Recruiting
Pain Control After Ear Surgery (Mastoidectomy)
This study tests a pain-blocking injection to reduce pain after a specific type of ear surgery (mastoidectomy). It may help you feel less pain after your operation.
IstanbulAges 18 years+ - NCT07672015RecruitingPhase 4
Testing a new pain drug in surgery patients at risk for opioid dependence
This trial tests a new painkiller called suzetrigine for post-surgery pain. It's designed for people whose medical records suggest they may have a higher chance of needing strong painkillers (opioids) long after surgery. We want to see if suzetrigine works better at preventing that.
La Jolla, CaliforniaAges 18 years+ - NCT06411795RecruitingPhase 2
Comparing two pain relief methods after Whipple surgery
This study compares two ways to manage pain after Whipple surgery: a long-lasting numbing injection near the belly muscles (rectus sheath block) versus an epidural (a tube placed in your back). The goal is to see which method provides better pain relief and recovery.
Minneapolis, MinnesotaAges 18 years+ - NCT06785571RecruitingPhase 2/Phase 3
Pain relief study for ICU patients on a ventilator
This study tests a painkiller called nalbuphine for ICU patients on a breathing machine. It aims to see if it controls pain as well as or better than usual care, with fewer side effects.
Wuhan, HubeiAges 18–80 - NCT06765772Recruiting
Nerve blocks for pain relief during tummy tuck surgery
This trial compares two types of nerve blocks (with numbing medicine) to reduce pain during and after tummy tuck surgery. The goal is to see if combining two blocks works better than one block alone.
Cairo, Cairo GovernorateAges 21–60 - NCT07401641Recruiting
Pain control study for oral cancer surgery
This study tests two different pain medicines (dezocine or nalbuphine) combined with sufentanil to see which helps better control pain after oral cancer surgery with free flap reconstruction. It also looks at side effects and how well the transplanted tissue survives.
Guangzhou, GuangdongAges 18–70 - NCT07245303Recruiting
How Light Affects Pain in Chronic Pain
This study looks at how different kinds of light might change pain levels in people with chronic widespread pain, like fibromyalgia. By using brain scans (MRI), researchers hope to find new ways to manage pain without medication.
Chapel Hill, North CarolinaAges 18 years+ - NCT07374354Recruiting
Pain and anxiety control for kids with MIH
This study tests a pain-relieving medicine given before dental treatment to see if it helps reduce pain and anxiety in children with molar incisor hypomineralization (MIH), a condition that causes weak enamel on molars and front teeth.
GizaAges 6–12 - NCT06990893Recruiting
Oliceridine vs morphine for pain after lumbar surgery
This study compares a new pain medicine called oliceridine with morphine or sufentanil to see which works better after lumbar spine surgery. It aims to find a safer and more effective way to manage pain after your operation.
Anqing, AnhuiAges 18–65 - NCT05925465Recruiting
Nerve block during elective facial surgery
This study tests a numbing “nerve block” to see how well it controls pain for people having planned facial/jaw surgery. If you’re eligible, you’d receive the study’s nerve-block approach during your operation.
Al Mansurah, MansouraAges 18–60 - NCT07219771RecruitingPhase 3
Testing MOTYS injection for knee osteoarthritis pain
This trial tests an injection called PTP-001 (MOTYS) for people with mild to moderate knee osteoarthritis. It aims to see if the injection can reduce knee pain and improve function.
Birmingham, AlabamaAges 40–80 - NCT06685107Recruiting
Virtual reality for pain relief in older ER patients
This trial tests if using virtual reality along with standard pain medication helps reduce pain better than medication alone for older adults with muscle or joint pain in the emergency room.
Brooklyn, New YorkAges 65–120 - NCT05893030Recruiting
Monitoring pain and sleep medicines to prevent complications after surgery
This study looks at whether closely monitoring opioid and sleep medicines during and after surgery can lower organ problems and death in older adults at high risk. If you qualify, your team will track how these medicines are given to help keep you safer in the postoperative period.
AmiensAges 75 years+ - NCT06759818Enrolling by invitation
Vagus nerve stimulation for heart protection after lung surgery in older adults
This trial tests if a gentle ear stimulation device can protect the heart after lung surgery in patients aged 60 and older. It is for those having a planned lung procedure (lobectomy, segmentectomy, or wedge resection) through small chest incisions.
Jiaxing, ZhejiangAges 60 years+ - NCT07250230Recruiting
Nicotine patch for pain after lung surgery in male smokers
This study tests if a high-dose nicotine patch worn before and after lung surgery can reduce pain in men who smoke but are quitting for the procedure. It aims to help manage pain during recovery.
Zhengzhou, HenanAges 18–75 - NCT07275450Recruiting
Ultrasound-guided numbing vs general anesthesia for ear surgery
This study compares numbing the ear with ultrasound guidance versus general anesthesia for tympanoplasty (eardrum repair). It aims to see which method offers better pain control and recovery.
ZagazigAges 21–65 - NCT06905340Recruiting
Pain-guided opioid use during surgery with regional anesthesia
This trial uses a special monitor (NOL index) to help doctors give just the right amount of pain medicine during surgery. It is for people having trauma or orthopedic surgery who are also getting regional anesthesia.
HamburgAges 18 years+ - NCT07253012Recruiting
AI pain relief assistant for surgery patients
This trial tests a computer system that helps manage pain during surgery. It may be an option if you are having a planned surgery lasting between 2 and 4 hours.
SantiagoAges Any age - NCT06083298Recruiting
Nerve blocks for pain after cervical spine surgery
This trial tests two types of nerve blocks to see which works better for pain after back-of-the-neck surgery. It aims to help patients have less pain and use less opioid medicine.
Zagazig, AlsharqiaAges 21–60 - NCT07307495Recruiting
Pain relief after back surgery and its effect on recovery
This study tests a new painkiller, oliceridine fumarate, given through a pump after lumbar spine surgery. The goal is to see if it helps the bowels and stomach recover faster compared to standard pain relief.
Xi'an, ShaanxiAges 18–75 - NCT07284615Recruiting
Nerve Block vs. Wound Injection for Hip Replacement Pain
This trial compares two pain-relief methods after hip replacement surgery: a nerve block (numbing the hip area) versus a numbing injection into the wound. The goal is to see which provides better pain control.
Cinisello Balsamo, MilanoAges 18 years+
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Common questions
- Are there clinical trials for patient controlled analgesia?
- Yes. Clin2 currently lists 55 recruiting patient controlled analgesia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a patient controlled analgesia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a patient controlled analgesia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.