Clinical trials
Patient Safety clinical trials
Below are recruiting patient safety clinical trials, each written for real people, not researchers. We’re tracking 1,334 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07159087Enrolling by invitation
New drug balloon for re-narrowed stents
This trial tests a new drug-coated balloon (Genoss SCB) versus an existing one (SeQuent Please NEO) for people whose heart stents have re-narrowed. It aims to see which balloon better keeps the artery open.
Gyeonggi-doAges 19 years+ - NCT06376968Recruiting
Testing a new dialysis option for low blood pressure
This study tests a new dialysis option called 'Biologic Fusion' that may help people who often have low blood pressure during dialysis. It compares this new method to standard dialysis to see if it is safer and works better.
Bologna, Emilia-RomagnaAges 18 years+ - NCT07413042RecruitingPhase 1
Radiation drug combined with immunotherapy for extensive-stage small cell lung cancer
This trial tests a combination of a radioactive drug ([225Ac]Ac-DOTATATE) and an immunotherapy drug (Tislelizumab) as maintenance treatment for people with extensive-stage small cell lung cancer (ES-SCLC) whose tumors have a specific protein (SSTR). If you have completed first-line treatment and your cancer shows SSTR on a PET scan, this study may be an option.
Beijing, Beijing MunicipalityAges 18–80 - NCT05372640RecruitingPhase 1
Drug combo trial for rare cancers with shared NUT features
This Phase 1 trial tests the safety and early signs of effectiveness of combining two anti-cancer drugs (ZEN003694 and abemaciclib) in teens and adults with metastatic or unresectable NUT carcinoma, breast cancer, and other solid tumors. It may help by finding a safer dose and whether the drug combination can shrink or control tumors that do not respond to standard treatments.
Los Angeles, CaliforniaAges 12 years+ - NCT06104007Recruiting
Genoss balloon for narrowed heart stents
This study follows patients who have already received a special drug-coated balloon (Genoss® DCB) to treat a re-narrowed heart stent. It aims to see how safe and effective the balloon is in the long term.
SeoulAges 19 years+ - NCT06349980RecruitingPhase 2
Study of three drugs for liver cancer not yet treated
This trial is testing a combination of three drugs (HLX10, HLX04, and HLX53) to find the best dose and see if they help people with advanced liver cancer who have not had systemic treatment before. The goal is to shrink tumors and improve survival.
ShanghaiAges 18 years+ - NCT06697301RecruitingPhase 2/Phase 3
New drug with pembrolizumab for advanced melanoma
This trial tests a new drug (EIK1001) combined with the standard immunotherapy pembrolizumab (Keytruda) for people with advanced melanoma that cannot be removed by surgery or has spread. The goal is to see if adding EIK1001 is more effective than placebo plus pembrolizumab.
Chandler, ArizonaAges 18 years+ - NCT06728852RecruitingPhase 2
Vorolanib for advanced lung cancer after other treatments
This trial tests a targeted therapy pill called Vorolanib for people with advanced non-small cell lung cancer who have already tried at least two other treatments. It aims to see if the drug can help shrink or control the cancer.
Guangzhou, GuangdongAges 18–70 - NCT07157033RecruitingPhase 1/Phase 2
Testing XER-001 with radiation for advanced pancreatic cancer
This trial tests a new way to deliver a drug called amifostine (XER-001) alongside intense radiation therapy (SBRT) for people with locally advanced pancreatic cancer that can't be surgically removed. The goal is to see if it's safe and effective at protecting healthy tissue while targeting the tumor.
Duarte, CaliforniaAges 18 years+ - NCT07280156RecruitingPhase 2
Study of PRX-115 for gout with or without methotrexate
This trial tests a new medicine, PRX-115, given through a vein, to see if it lowers uric acid levels in people with gout who haven't had success with standard treatments. Some participants will also take methotrexate, and the results are compared to a placebo (a dummy infusion).
Little Rock, ArkansasAges 18 years+ - NCT07397390Enrolling by invitation
Study of a new scoring balloon for leg artery blockages with heavy calcium buildup
This study tests a new balloon device that scores the artery walls to treat leg artery blockages with heavy calcium deposits. It aims to see if the device helps prepare the vessel safely and effectively before placing a stent.
Dalian, LiaoningAges 18–85 - NCT06693375RecruitingPhase 2
Testing a new imaging agent for rectal cancer lymph nodes
This trial tests a new nanoparticle-based imaging agent to better see lymph nodes near the rectum. It first checks healthy volunteers for safety, then studies people with rectal cancer to see if it can help guide surgery.
UppsalaAges 18–99 - NCT06293651RecruitingPhase 1/Phase 2
Study of DA-4505 alone or with pembrolizumab for advanced solid tumors
This trial tests a new drug called DA-4505, given alone or with another drug (pembrolizumab), for people with advanced solid tumors that cannot be removed by surgery or have spread. The goal is to see if it is safe and works against the cancer.
SeoulAges 18 years+ - NCT04617756RecruitingPhase 2
Durvalumab plus chemo before surgery for high-risk upper urinary tract cancer
This trial studies whether durvalumab (an immunotherapy) given with chemotherapy before surgery can improve outcomes for people with high-risk cancer in the kidney pelvis or ureter. It is mainly looking at safety and effectiveness in shrinking or controlling the cancer before treatment continues.
Paris, Paris Cx 20Ages 18 years+ - NCT05922345RecruitingPhase 3
Study drug vs docetaxel for advanced lung cancer after prior treatment
This Phase 3 trial compares AL2846 pills plus TQB2450 injections against standard chemotherapy (docetaxel) in people with advanced non-small cell lung cancer. You may qualify if your cancer has progressed after platinum chemotherapy and immunotherapy, and if certain tumor genetic tests are negative.
Hefei, AnhuiAges 18–75 - NCT06266832RecruitingPhase 2
Short-course radiation with immunotherapy and chemo for rectal cancer
This trial tests a combination of short-course radiation, an immunotherapy drug (adebrelimab), and chemotherapy (CAPEOX) before surgery to help preserve the rectum in people with MSS/pMMR ultra-low rectal cancer. The goal is to shrink the tumor enough to avoid removing the rectum.
Hangzhou, ZhejiangAges 18 years+ - NCT06620757Recruiting
Short-term single blood thinner after LAmbre device implant
This study tests whether it is safe and effective to use just one blood thinner (aspirin or clopidogrel) for a short time after getting a LAmbre device implanted to close off a heart pouch that can cause strokes. It is for people with atrial fibrillation who cannot take standard blood thinners long-term.
A CoruñaAges 18–100 - NCT06752577Recruiting
Stem cell treatment for chronic kidney disease safety study
This study tests whether a single infusion of stem cells from bone marrow is safe for people with chronic kidney disease (CKD). It aims to see if this treatment can help slow kidney function loss.
Jacksonville, FloridaAges 18 years+ - NCT06829459RecruitingPhase 3
New drug combo vs chemo for resistant lung cancer
This trial tests a combination of two targeted drugs (Glumetinib and Osimertinib) against standard chemotherapy for people with non-small cell lung cancer that has stopped responding to initial targeted therapy. It may be an option if your tumor has a specific genetic change called MET amplification or overexpression.
Beijing, Beijing MunicipalityAges 18 years+ - NCT01898416RecruitingPhase 2
5-ALA by mouth to reduce regrowth of desmoid tumors
This Phase 2 trial tests whether taking a medicine called 5-ALA by mouth after treatment can lower how often desmoid tumors come back in the same area. If you have a desmoid tumor that can be removed and you meet safety criteria, this study may help determine whether 5-ALA is effective and safe for you.
Tel Aviv, IsraelAges 18 years+ - NCT05601726RecruitingPhase 1/Phase 2
Study of a new drug for hard-to-treat AML or high-risk MDS
This early study tests a new medicine (ABD-3001) to see if it’s safe and tolerable, how the body handles it, and whether it shows early signs of helping people with relapsed or hard-to-treat AML or high-risk MDS. It may be an option if standard treatments have already failed and you can’t receive a stem cell transplant.
Marseille, FranceAges 18 years+ - NCT05836896RecruitingPhase 1
Safety check of BCMA CAR T-cells made from your own immune cells
This early-phase trial tests whether a personalized BCMA-targeting CAR T-cell treatment is safe and what dose is tolerable in people whose lymphoma or myeloma has come back or did not respond to prior treatment. If you qualify, the team will monitor you closely for side effects to find the safest maximum tolerated dose.
DresdenAges 18 years+ - NCT06498089RecruitingPhase 4
Comparing tailored vs. standard treatment for active Takayasu's arteritis.
This trial compares a personalized treatment plan based on your specific disease markers to standard care, aiming to find which is more effective and safer for active Takayasu's arteritis. It may help researchers learn how to better control inflammation and prevent flares.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06537583Recruiting
Ear stimulation after a STEMI heart attack
This study tests whether gentle electrical stimulation near your ear (tragus) can help stabilize your heart's rhythm and reduce inflammation after a STEMI heart attack. It may help lower the risk of future heart problems.
Semarang, Central of JavaAges 18–70
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Common questions
- Are there clinical trials for patient safety?
- Yes. Clin2 currently lists 1,334 recruiting patient safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a patient safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a patient safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.