Clinical trials
Pediatric Patients clinical trials
Below are recruiting pediatric patients clinical trials, each written for real people, not researchers. We’re tracking 348 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06997588RecruitingPhase 2
Alpelisib for pediatric and adult PROS
This trial tests a drug called alpelisib for children and adults with a rare overgrowth condition called PROS that is caused by a PIK3CA gene change. It aims to see if the drug can safely shrink overgrowth and improve symptoms.
St Louis, MissouriAges 2–100 - NCT06773026RecruitingPhase 2
Sodium Phenylbutyrate for MCADD in Children and Adults
This trial tests a medicine called sodium phenylbutyrate (ACER-001) to see if it helps people with MCADD, a genetic condition that affects how your body breaks down fats. If you have MCADD and the common gene change, you might be able to join.
Pittsburgh, PennsylvaniaAges 4 years+ - NCT05090345Recruiting
Registry for young people getting bone marrow transplants
This trial is a registry that follows children and young adults up to age 26 who are having a bone marrow transplant, to better understand complications related to blood vessel and organ injury. It may help future patients by improving how doctors predict and prevent these problems.
Rochester, MinnesotaAges birth–26 years - NCT07466459Enrolling by invitation
Better dialysis for kids
This study looks at improving how well dialysis removes waste from the blood and uses water in children. It may help make treatments more effective and efficient.
GhentAges Up to 18 years - NCT06773546Recruiting
Immune system disorders study for children and adults
This study looks at people with known or suspected inborn errors of immunity (problems with the immune system that you are born with). The goal is to improve how these conditions are diagnosed and managed. If you have immune system issues that started before age 50, you may be able to join.
Bologna, BolgonaAges Up to 50 years - NCT07464483Recruiting
Studying genetics in stem cell and CAR-T therapy patients
This trial analyzes genetic information from patients receiving a stem cell transplant or CAR-T therapy to better understand treatment outcomes. Participation may help researchers improve future therapies.
Bologna, BolognaAges Any age - NCT06049680RecruitingPhase 4
Safety study of SMOFlipid for patients needing IV nutrition
This trial tests if SMOFlipid, a special lipid emulsion given through an IV, is safe for children and adults who need most of their nutrition from IV for at least 8 weeks. It looks for side effects like essential fatty acid deficiency or liver problems.
Atlanta, GeorgiaAges 1 month–17 years - NCT03067181RecruitingPhase 3
Active surveillance and chemotherapy for germ cell tumors
This study looks at how to manage germ cell tumors in children and young adults using careful monitoring for some patients and chemotherapy for others. It aims to see whether these approaches can control the cancer while avoiding unnecessary treatment when possible.
Birmingham, AlabamaAges Any age - NCT04153994Recruiting
Numbing injection study for kids’ scoliosis back surgery pain
This trial tests whether a specific numbing injection (placed in the muscles of the back) can improve pain control for children having one-stage scoliosis surgery. It may help reduce post-surgery pain needs and improve comfort.
Palo Alto, CaliforniaAges Up to 18 years - NCT04959903RecruitingPhase 1/Phase 2
SMART101 after T-cell–depleted bone marrow transplant for blood cancers
This early-phase study tests SMART101 given after a T-cell–depleted (T-cell removed) donor bone marrow transplant. It aims to see if the treatment is safe and can help control certain high-risk blood cancers in children and adults.
New York, New YorkAges Any age - NCT05577754RecruitingPhase 2
Trial tests alpelisib for MCAP with PIK3CA mutations
This Phase 2 study tests alpelisib in children and adults with MCAP, a condition caused by a specific PIK3CA gene mutation. The goal is to see if the treatment is effective and safe, while carefully monitoring blood sugar and organ function.
AmiensAges 2–40 - NCT06185686Recruiting
Brain Network Changes in Kids with Brain Tumors After Proton Radiation
This study looks at how proton radiation affects brain networks in children and teens with brain tumors. It uses MRI scans and computer tasks to understand changes in the brain during and after treatment.
St Louis, MissouriAges 8–21 - NCT07692256RecruitingPhase 2
Empagliflozin for heart failure in children
This trial tests if empagliflozin, a diabetes medicine that also helps the heart, can improve symptoms in children with heart failure. It may help kids with severe symptoms or high levels of a heart stress marker called BNP.
Cairo, Cairo GovernorateAges 1 month–18 years - NCT07184476Recruiting
Measuring small blood vessels in kids having heart surgery
This study looks at tiny blood vessels in children with specific heart defects during surgery. It may help doctors better understand circulation and improve care.
Boston, MassachusettsAges 1 day–17 years - NCT07195032RecruitingPhase 4
MMR vaccine safety in kids after heart transplant
This trial tests whether the MMR (measles, mumps, rubella) vaccine is safe and works well for children who have had a heart transplant. It may help protect you from these diseases if you haven't had the vaccine or no longer have immunity.
Kansas City, MissouriAges 1–17 - NCT07223255Recruiting
Mediterranean diet study for children with cystic fibrosis
This study tests whether a Mediterranean-style diet can improve gastrointestinal health in children with cystic fibrosis. It requires families to follow the diet for 6 months and attend regular clinic visits.
Lebanon, New HampshireAges 3–18 - NCT02914067Recruiting
Testing brain scan and computer measures in young brain tumor patients
This study looks at “brain biomarkers,” meaning brain signals measured on MRI and thinking/learning tests on a computer. It may help researchers understand how brain tumors affect the brain and track changes over time.
St Louis, MissouriAges 4–18 - NCT07473947Recruiting
Study of bioabsorbable screws for ankle, knee, and elbow fractures in kids
This trial tests a special screw that dissolves over time to fix broken bones in the ankle, knee, or elbow. It may help children and teens avoid a second surgery to remove metal screws.
TurkuAges Up to 17 years - NCT06886529Recruiting
Patient and family involvement in cardiology care at SickKids
This study looks at how patients and families can be more involved in care for children admitted to the cardiology unit at SickKids. It may help improve how the hospital works with families.
TorontoAges Up to 18 years - NCT05634369RecruitingTeam says not enrollingPhase 1/Phase 2
NK cell and chemotherapy trial for relapsed soft tissue sarcoma
This early-phase trial studies a type of immune cell treatment (NK cells) made from donor cells, given with chemotherapy drugs gemcitabine and docetaxel. It’s for children and young adults whose bone or soft tissue sarcoma has come back or hasn’t responded to prior treatment.
South Birmingham, AlabamaAges 2–40 - NCT06796543Recruiting
Radiation for young patients with sarcoma that has spread
This trial tests whether targeted radiation can help children and young adults with sarcoma that has spread to a few spots in the body. It's for those who are newly diagnosed (Stratum A) or whose sarcoma has come back or worsened (Stratum B).
Washington D.C., District of ColumbiaAges Up to 39 years - NCT07680439RecruitingPhase 2
CAR T cell therapy study for children with DIPG brain tumor
This trial tests a new CAR T cell therapy (BCB-276) for children and young adults with a type of brain tumor called DIPG. The therapy uses your own immune cells that are specially trained to attack the cancer.
Los Angeles, CaliforniaAges 1–26 - NCT05994690RecruitingPhase 3
Newly diagnosed pediatric AML trial with extra treatment options
This trial studies different treatment plans for children and teens newly diagnosed with AML (a type of blood cancer). Depending on the child's tumor markers and risk group, they may be offered an extra drug (quizartinib) or a targeted antibody (Mylotarg) to see if it improves outcomes.
Utrecht, UtrechtAges 1 day–18 years - NCT04925609RecruitingPhase 1/Phase 2
Brigatinib for young people with ALK-positive cancer
This trial tests brigatinib, a targeted pill medicine, in children and young adults with ALK-positive cancers (including ALCL and IMT, plus some other solid tumors). It’s designed to see how well it works and what side effects it causes in people whose tumors have a specific ALK change.
ParisAges 1–25
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Common questions
- Are there clinical trials for pediatric patients?
- Yes. Clin2 currently lists 348 recruiting pediatric patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pediatric patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pediatric patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.