Clinical trials
Pediatric Patients clinical trials
Below are recruiting pediatric patients clinical trials, each written for real people, not researchers. We’re tracking 348 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04485559RecruitingPhase 1
Trametinib and everolimus for recurrent gliomas
This trial tests two drugs, trametinib and everolimus, for children and young adults with recurrent or progressive gliomas (a type of brain tumor). The goal is to see if this drug combination is safe and effective in treating these tumors.
Birmingham, AlabamaAges 1–25 - NCT04604418Recruiting
Tracking outcomes during non-heart procedures in children with heart defects
This study looks at how children with congenital heart disease do during routine non-heart procedures, including medical or minor treatments that are not heart-related. It also measures how much health care they use afterward, which may help improve care planning for families.
Los Angeles, CaliforniaAges Up to 21 years - NCT07444619RecruitingPhase 1
Combination drugs for returning soft tissue sarcoma in young people
This trial tests if combining four drugs (pazopanib, trabectedin, ipilimumab, and nivolumab) can help treat soft tissue sarcomas that have come back. It is for children and young adults up to age 30.
Houston, TexasAges 1–30 - NCT07519863RecruitingPhase 2
Comparing sedation medicines for burned children during procedures
This study tests two different sedation medicine combinations to see which one reduces confusion and agitation (called delirium) when children with burn injuries need procedures done. The goal is to find the safest, most comfortable option for your child during treatment.
CairoAges 3–16 - NCT06468618Recruiting
Sleep and stress program for kids getting stem cell transplant
This study tests a program to help children ages 9–17 who are getting a stem cell transplant at Boston Children's Hospital. It aims to improve sleep and reduce stress for both the child and their family.
Boston, MassachusettsAges 9–17 - NCT07718204Recruiting
Medication help for kids after bone marrow transplant
This study tests a program that helps caregivers remember to give their child's oral medications after a bone marrow transplant. If you are the main caregiver for a child who had a transplant and is still in the hospital, this trial might be for you.
Columbus, OhioAges birth–12 years - NCT04777656RecruitingPhase 3
Crohn’s exclusion diet plus usual care for kids
This study tests whether a specific “exclusion diet” (removing certain foods) added to standard treatment can better control unstable Crohn’s disease in children. It may help reduce inflammation and flare-ups when symptoms are not controlled by usual medicines.
BronAges 6–17 - NCT05906576RecruitingPhase 4
Infliximab monitoring study for children with Crohn’s disease
This study keeps track of how infliximab works and how safe it is in Chinese children with moderate-to-severe active Crohn’s disease. You may be eligible if this is the first time your child is starting infliximab and you agree to provide study information.
BeijingAges 6–17 - NCT06128070RecruitingPhase 2
Preventing GVHD after stem cell transplant for leukemia
This trial tests adding ruxolitinib to standard drugs (tacrolimus and methotrexate) to prevent graft-versus-host disease in children and young adults undergoing a stem cell transplant for acute leukemia or myelodysplastic syndrome. The goal is to lower the risk of GVHD and improve transplant outcomes.
Duarte, CaliforniaAges 2–22 - NCT06177067RecruitingPhase 1
Study of 3 drugs for young AML patients with genetic changes
This trial tests a combination of three drugs (revumenib, azacitidine, and venetoclax) for children and young adults with a hard-to-treat type of leukemia that has a specific genetic change. The goal is to see if this new mix can help when standard treatments have not worked.
San Diego, CaliforniaAges 1–30 - NCT06651242Recruiting
Support for young cancer patients and their parents
This trial tests a decision-support program for children and teens with cancer and their parents. It aims to help families communicate and make choices together during treatment.
Kaohsiung CityAges 7–20 - NCT06914479RecruitingPhase 1
Gene therapy and valacyclovir for recurrent brain tumors in young people
This trial tests a new gene therapy that uses two special viruses and an oral antiviral drug (valacyclovir) to treat brain tumors that have come back in children and young adults. The therapy is given right after surgery to remove the tumor, with the goal of helping your immune system fight the cancer.
Ann Arbor, MichiganAges 3–39 - NCT07359911Recruiting
Exercise program for teens and young adults with sarcoma starting chemo
This study tests whether a special exercise program can help young people with sarcoma better tolerate chemotherapy. It may improve how well they respond to treatment and reduce side effects.
Miami, FloridaAges 12–39 - NCT03786549Recruiting
Sickle cell care transition program for teens and families
This study tests a structured program to help teens with sickle cell disease smoothly transition from pediatric care to adult care, with support for parents or legal guardians. It may help families coordinate care sooner and more confidently during this change.
Fort-de-France-La Martinique, La MartiniqueAges 16–17 - NCT06939322Recruiting
Long-term monitoring app for childhood cancer survivors
This trial tests whether a special software (LOG-AFTER) helps people who had cancer before age 25 keep up with long-term screenings. It aims to make follow-up care easier and more consistent.
Angers, Maine Et LoireAges 15 years+ - NCT05127148Recruiting
Real-world study of pediatric-like treatment for Ph-negative ALL
This study follows how well a “pediatric-style” treatment plan works in teens and young adults with Ph-negative acute lymphoblastic leukemia (ALL) in real-world care. It mainly aims to understand outcomes and safety for patients who fit the specific leukemia and health criteria.
Paraná, Entre Ríos ProvinceAges 18–40 - NCT07551583RecruitingPhase 2
Nivolumab plus chemotherapy for early-stage Hodgkin lymphoma in young people
This study tests a combination of a newer immunotherapy drug (nivolumab) with standard chemotherapy (AVD) in children, teens, and young adults with newly diagnosed, early-stage Hodgkin lymphoma—a blood cancer affecting lymph nodes. The goal is to see if adding immunotherapy improves outcomes while being tolerable for this age group.
Houston, TexasAges 2–21 - NCT05749419Recruiting
Vaccines for children with disabilities and long-term conditions
This study looks at how vaccines work in children who have disabilities, long-term (chronic) illnesses, or conditions they were born with. It may help improve vaccine care for kids who need extra support.
JerusalemAges Any age - NCT06561074RecruitingPhase 2
Study of calaspargase, decitabine, and venetoclax for young T-cell cancer
This trial tests a combination of three drugs (calaspargase, decitabine, and venetoclax) for children, teens, and young adults with T-cell leukemia or lymphoma that has come back or not responded to treatment. The goal is to see if this combination can help destroy cancer cells.
Houston, TexasAges 1 month–21 years - NCT06847269RecruitingPhase 2
CAR T cell therapy for children and young adults with CD19+ leukemia
This trial tests an immunotherapy called CAR T cells for leukemia that has come back or is hard to treat. It aims to use your own immune cells to fight the cancer.
Memphis, TennesseeAges Up to 21 years - NCT07071051Recruiting
Study of calaspargase pegol on blood clotting in pediatric leukemia
This study looks at how a chemotherapy drug called calaspargase pegol affects blood clotting in children and young adults with leukemia. It will help doctors understand if changes in clotting are common and safe.
Rochester, MinnesotaAges 2–22 - NCT07473518Recruiting
Thyroid cancer after childhood radiation therapy
This study looks at thyroid cancer in people who had radiation therapy as children, comparing them to people who did not have radiation. The goal is to see how often thyroid cancer develops after childhood radiation.
BolognaAges 10–43 - NCT07202507Recruiting
Can a sensory room help with anxiety during chemo?
This study tests if a special relaxing room (SNOEZELEN) can help reduce anxiety in children and teens getting chemotherapy. The goal is to see if the room makes the hospital stay less stressful.
LilleAges 8–18 - NCT07084935Recruiting
Comparing pain monitors during children’s surgery
This trial compares two devices that measure pain levels during surgery in children. It may help doctors better manage pain for children having planned surgery with general anesthesia.
Nijmegen, GelderlandAges 1–12
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Common questions
- Are there clinical trials for pediatric patients?
- Yes. Clin2 currently lists 348 recruiting pediatric patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pediatric patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pediatric patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.