Clinical trials · Ohio
Pediatrics clinical trials in Ohio
We’re tracking 152 recruiting pediatrics studies with a site in Ohio — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Ohio
- NCT04715685Recruiting
Mind-body balance program for children with migraine
This trial studies a mind-body balance approach to help reduce symptoms and disability from pediatric migraine. You may join if your child has migraine headaches and can follow study routines, including keeping a headache diary.
Cincinnati, OhioAges 10–17 - NCT04726241RecruitingPhase 1/Phase 2
Testing blood and bone marrow samples in young leukemia patients
This trial looks at blood and bone marrow samples from children and teens whose leukemia has come back or is hard to treat. The goal is to better understand the disease and guide future options for these patients.
Akron, OhioAges Up to 22 years - NCT04774718RecruitingPhase 1/Phase 2
Alectinib for ALK-fusion tumors in children and teens
This trial tests how safe alectinib is and how it works in children and teens with solid tumors or brain (CNS) tumors that have an ALK gene fusion. It’s for tumors that have come back, worsened, or don’t have a good standard treatment.
Cincinnati, OhioAges Up to 17 years - NCT05376267Recruiting
Testing how long cooling lasts after pediatric cardiac arrest
This study tests whether using body cooling for different lengths of time helps children recover better after an out-of-hospital cardiac arrest. It focuses on children who remain very unresponsive after resuscitation and need a breathing tube and steady temperature control.
Akron, OhioAges 2 days–17 years - NCT04991389RecruitingPhase 4
Test a breathing study plan for kids with sleep apnea after surgery
This trial studies how to improve outcomes for children who still have obstructive sleep apnea after having their tonsils and adenoids removed. It uses computer modeling (based on breathing/airflow) and may include a special breathing gas during testing in some parts of the study.
Cincinnati, OhioAges 3–18 - NCT05003986RecruitingPhase 2
Sparsentan for children with protein leaking kidney diseases
This Phase 2 study tests sparsentan in children with certain kidney diseases that cause high amounts of protein in the urine. It aims to see if the medicine can reduce kidney damage signals and protein leakage compared with standard care.
Columbus, OhioAges 1–17 - NCT05076175RecruitingPhase 2/Phase 3
Oral ozanimod for children with moderate to severe ulcerative colitis
This trial tests whether an oral medicine called ozanimod can improve ulcerative colitis (UC) in children whose disease is moderate to severe. It’s meant for kids who didn’t fully respond—or couldn’t tolerate—standard UC treatments.
Cleveland, OhioAges 2–17 - NCT05096481RecruitingPhase 2
Vaccine trial for children with certain brain tumors
This Phase 2 study tests a vaccine made to target CMV (a virus) in order to treat children with medulloblastoma or newly diagnosed high-grade glioma/DIPG. If you’re eligible, you’d receive the study vaccine and the team would closely watch how well it’s tolerated and how your cancer responds.
Cincinnati, OhioAges 3–39 - NCT05101551RecruitingPhase 1
Talazoparib with chemotherapy for relapsed childhood AML
This Phase 1 study tests whether talazoparib combined with chemotherapy is safe and potentially effective for children and young adults whose leukemia has come back or did not respond. It focuses on finding the best way to give the treatment and watching for side effects.
Cincinnati, OhioAges Up to 21 years - NCT05112237Recruiting
Study of children’s heart disease caused by MYBPC3 gene changes
This is an observational study that follows children under 18 with cardiomyopathy caused by certain MYBPC3 gene mutations. It aims to better understand how the disease changes over time, which may help future treatments be better targeted.
Middlefield, OhioAges birth–18 years - NCT05121324RecruitingPhase 3
Tested higher-dose seizure medicine for children during EMS care
This trial studies the best dose of a seizure medicine for children who are actively seizing while emergency medical teams are treating them. It may help EMS crews give safer, more effective treatment during transport.
Columbus, OhioAges 6 months–13 years - NCT05135975RecruitingPhase 2
Cabozantinib maintenance to help stop pediatric cancer from growing
This trial studies cabozantinib given after standard treatment to try to keep high-risk pediatric solid tumors from coming back or getting worse. It is offered to children and young adults whose cancer has not fully disappeared but is not progressing at the start of this maintenance phase.
Columbus, OhioAges 1.5 years–40 years - NCT05233397RecruitingPhase 2
Actemra for children and young adults with craniopharyngioma
This trial studies Actemra (tocilizumab) to slow or shrink adamantinomatous craniopharyngioma, a brain tumor that can recur after treatment. You may be eligible if you’re within the age range and have measurable tumor on scan, with specific rules about prior therapy and recovery.
Columbus, OhioAges 1–39 - NCT05250180Recruiting
Animal-assisted therapy for kids after brain injury
This study looks at whether guided time with therapy animals helps children recover after an acquired brain injury, and what factors affect whether it works. Families may be asked to allow animal sessions and track responses over time.
Cincinnati, OhioAges 4–24 - NCT05286788RecruitingPhase 2
MEKTOVI for children with adamantinomatous craniopharyngioma
This Phase 2 trial tests MEKTOVI® to treat pediatric adamantinomatous craniopharyngioma (a type of brain tumor). It may help shrink or control the tumor after it has come back or grown again.
Columbus, OhioAges 1–39 - NCT05303064RecruitingPhase 3
Study of weight gain medicine for teens with certain mood or psychosis
This Phase 3 study tests a treatment aimed at reducing unhealthy weight gain in teens with schizophrenia or bipolar I disorder, using changes in BMI (a height-and-weight measure). It may help families who are concerned about weight changes that can happen with some psychiatric medicines.
Cincinnati, OhioAges 10–17 - NCT05371613RecruitingPhase 2/Phase 3
Testing tividenofusp alfa vs idursulfase for MPS II
This trial compares a new treatment (tividenofusp alfa) to the current standard treatment (idursulfase) in children and young adults with MPS II. It’s looking to see which option works better and is safe, especially based on age and whether the disease affects the brain.
Cincinnati, OhioAges 2–25 - NCT05469373Recruiting
Testing ESIS for children with hard-to-treat epilepsy
This trial studies ESIS in children and teens (ages 1 to 30) who have epilepsy that has not been controlled by medications. It may help by improving how doctors evaluate and treat seizures, especially when an additional brain-monitoring test is planned.
Cincinnati, OhioAges 1–30 - NCT05476770RecruitingPhase 1
Tagraxofusp for children with CD123-positive leukemia
This study tests tagraxofusp, a medicine that targets a marker called CD123 on cancer cells, in children and young adults whose leukemia or lymphoma has come back or is resistant to treatment. It may help by shrinking the cancer and improving disease control after standard therapies have not worked.
Cleveland, OhioAges 1–21 - NCT05509777RecruitingPhase 3
Mirikizumab for children with active Crohn’s disease
This study tests mirikizumab to reduce inflammation and symptoms in children with Crohn’s disease that is currently active. It may help if your Crohn’s has not improved enough (or stopped working) with at least one other Crohn’s medicine.
Dayton, OhioAges 2–17 - NCT05538208RecruitingPhase 2
Children with lupus kidney inflammation using mycophenolate
This Phase 2 study tests how well the medicine mycophenolate mofetil (MMF) works for children and teens with lupus nephritis that is “proliferative” (a specific biopsy type). You may qualify if your kidney biopsy and current treatment match the study’s targets and you can follow frequent visits and testing.
Akron, OhioAges 8–20 - NCT05544019RecruitingPhase 1
Testing an investigational drug for mature B-cell cancers
This early (Phase 1) study tests SGR-1505, an experimental treatment, in people with certain mature B-cell cancers. It’s mainly designed to see how the drug works in the body and to check safety, and it may offer an option if standard treatments aren’t enough.
Columbus, OhioAges 18 years+ - NCT05550324Recruiting
Pediatric heart disease patient data repository
This trial is a data repository that collects information from children with heart (cardiovascular) conditions and related syndromes. It focuses on organizing cases and comparing groups to help researchers better understand pediatric heart disease.
Columbus, OhioAges Any age - NCT05622461Recruiting
Recovery support program for children after traumatic brain injury
This trial supports families during the early weeks after a child’s brain injury and hospital stay. It aims to help caregivers and children move toward recovery with better support after discharge.
Cincinnati, OhioAges 18 years+
Where these studies are running in Ohio
Institutions with a site for the recruiting pediatrics studies listed above.
- Cincinnati Children's Hospital Medical Center · 17 studies
- Nationwide Children's Hospital · 11 studies
- Cleveland Clinic · 3 studies
- Children's Hospital Medical Center of Akron · 2 studies
- Dayton Children's Hospital · 2 studies
- Rainbow Babies and Children's Hospital · 2 studies
- Akron Children's Hospital
- Alkermes Investigational Site
What taking part in a pediatrics study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Pediatrics trials in other states
Common questions
- Are there pediatrics clinical trials in Ohio?
- Yes. We're currently tracking 152 recruiting pediatrics studies with a site in Ohio, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pediatrics study in Ohio?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Ohio to take part?
- Not necessarily. These studies have a site in Ohio, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pediatrics trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pediatrics studies open in Ohio regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.