Clinical trials
Pediatrics clinical trials
Below are recruiting pediatrics clinical trials, each written for real people, not researchers. We’re tracking 1,359 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05509777RecruitingPhase 3
Mirikizumab for children with active Crohn’s disease
This study tests mirikizumab to reduce inflammation and symptoms in children with Crohn’s disease that is currently active. It may help if your Crohn’s has not improved enough (or stopped working) with at least one other Crohn’s medicine.
Los Angeles, CaliforniaAges 2–17 - NCT05538208RecruitingPhase 2
Children with lupus kidney inflammation using mycophenolate
This Phase 2 study tests how well the medicine mycophenolate mofetil (MMF) works for children and teens with lupus nephritis that is “proliferative” (a specific biopsy type). You may qualify if your kidney biopsy and current treatment match the study’s targets and you can follow frequent visits and testing.
San Francisco, CaliforniaAges 8–20 - NCT05511987Recruiting
Thopaz+ digital chest tube vs standard drainage in kids
This study compares a digital chest tube drainage system (called Thopaz+) to the usual (analog) drainage in children who need a chest tube. The goal is to see if the digital system works better or is easier for recovery after a pneumothorax or lung surgery.
Oklahoma City, OklahomaAges birth–17 years - NCT05535361Recruiting
Testing a bowel device for short bowel syndrome patients
This trial studies whether the Eclipse XL1 system is safe and may help people with short bowel syndrome, in both children and adults. It will check how well the approach works and watch for side effects over the study period.
Palo Alto, CaliforniaAges 3 months–65 years - NCT05521399Recruiting
Heart transplant patients get a heart MRI check
This study renews research using heart MRI scans to learn more about heart transplant patients and compare them with healthy control scans. It may help researchers understand heart function after transplant and improve future imaging care.
Chicago, IllinoisAges Any age - NCT05524610Recruiting
Screening plan for sexual health in young cancer survivors
This study tests a new way to screen for sexual problems in teens and young adults (ages 15–24) who have had childhood cancer. The goal is to better spot issues and improve care during survivorship.
Aurora, ColoradoAges 15–24 - NCT05512169Recruiting
Genetic study in Indian children with newly diagnosed leukemia
This study looks at genetic (DNA) differences to understand acute lymphoblastic leukemia (ALL) in Indian children and how treatments may fit better. You may be able to join if your child is newly diagnosed, meets the study’s treatment plan rules, and provides consent.
New DelhiAges 1–18 - NCT05478720RecruitingPhase 1/Phase 2
Tested medicine for children with cerebral malaria
This early-stage study tests how a medicine (involving ondansetron and ceftriaxone) works in people with malaria. It especially focuses on children with cerebral malaria to see if it can improve safety and early effectiveness.
BlantyreAges 1 year+ - NCT05481437Recruiting
Surveying brentuximab for children with Hodgkin lymphoma
This trial is a survey study that looks at how brentuximab vedotin is used in children with Hodgkin lymphoma. It focuses on people whose tumor is CD30-positive and who have not had prior treatment, to see how the drug fits with a standard chemotherapy plan (AVD).
Tokyo, TokyoAges Up to 18 years - NCT05491525RecruitingPhase 2/Phase 3
Vibegron for children with nerve bladder using intermittent catheter
This study tests how well and how safely vibegron works long-term in children (ages 2 to under 18) with a nerve-related bladder condition, who regularly use intermittent catheterization. It also tracks how the body processes the medicine and whether it helps bladder control over time.
Little Rock, ArkansasAges 2–17 - NCT05464888Recruiting
Animal-assisted therapy for kids’ dental visits
This study tests whether working with a trained animal can make dental checkups and cleanings easier for children ages 4 to 8. It may help reduce fear and improve how kids tolerate routine dental care.
Chapel Hill, North CarolinaAges 4–8 - NCT05480449RecruitingPhase 1/Phase 2
Personalized CAR-T for children with high-risk B-ALL
This trial studies a personalized type of immune therapy (CAR-T) made from your own cells to treat pediatric B-ALL that has returned or not responded to prior treatment. It aims to see how well this manufactured CAR-T works and how safely it can be given.
Philadelphia, PennsylvaniaAges birth–29 years - NCT05463289Recruiting
AI helps children with diabetes get eye exams
This study tests an AI-based way to help check children’s eyes for signs of diabetic retinopathy (diabetes-related eye disease). It may improve how quickly and consistently eye screening is done for kids with diabetes.
Baltimore, MarylandAges 8–21 - NCT05432648Recruiting
Fiber food introduction for children with short bowel syndrome
This trial tests if slowly adding fiber to the diet helps children with short bowel syndrome. It looks at how fiber affects digestion and overall health.
Philadelphia, PennsylvaniaAges 4 months–18 years - NCT05418959Enrolling by invitationPhase 1
Genetic study to better assess kids’ unusual skin spots
This Phase 1 study looks at genetic risk factors in children with unusual skin lesions. The goal is to help doctors better decide which spots should be closely watched or safely biopsied.
Boston, MassachusettsAges birth–20 years - NCT05442671Recruiting
Exercise coaching program for children with pulmonary hypertension
This trial tests whether a structured exercise program, done with remote support, is safe and helpful for children with pulmonary hypertension. It aims to improve how well kids function day-to-day while they stay on their usual PH medications.
Philadelphia, PennsylvaniaAges 8–18 - NCT05454618Recruiting
Deciding to join a pediatric cancer treatment trial
This study looks at the decision-making process for parents (or legal guardians) when their child is newly diagnosed with cancer and might consider enrolling in a treatment trial. It may help improve how families are informed and supported when making these choices.
Memphis, TennesseeAges Any age - NCT05457829RecruitingPhase 2
Testing two chemotherapy combinations for relapsed pediatric rhabdomyosarcoma
This trial compares two treatment combinations—liposomal doxorubicin plus irinotecan versus a different chemotherapy plan—in children and teens whose rhabdomyosarcoma came back or did not respond. It aims to see which option works better and is safer for children who have had prior cancer treatment.
GuangzhouAges 6 months–18 years - NCT05441813RecruitingPhase 2
Coconut oil mouth rinse to prevent mouth sores during transplant
This study tests whether a coconut oil mouth rinse can help prevent mouth sores in children and young adults who are about to receive intense chemotherapy for a stem cell transplant. If mouth sores can be prevented, it may make treatment more comfortable and reduce complications.
Charlotte, North CarolinaAges 7–26 - NCT05372640RecruitingPhase 1
Drug combo trial for rare cancers with shared NUT features
This Phase 1 trial tests the safety and early signs of effectiveness of combining two anti-cancer drugs (ZEN003694 and abemaciclib) in teens and adults with metastatic or unresectable NUT carcinoma, breast cancer, and other solid tumors. It may help by finding a safer dose and whether the drug combination can shrink or control tumors that do not respond to standard treatments.
Los Angeles, CaliforniaAges 12 years+ - NCT05366218RecruitingPhase 1/Phase 2
Tafasitamab for kids with high-risk B-cell leukemia after relapse
This Phase 1/2 study tests tafasitamab in children and teens with B-lineage acute lymphoblastic leukemia (ALL) that has come back or did not respond. It is mainly for patients with specific high-risk leukemia changes and/or leukemia markers that stay after stem cell transplant or CAR T-cell therapy.
Freiburg im Breisgau, Baden-WurttembergAges 3–18 - NCT05376267Recruiting
Testing how long cooling lasts after pediatric cardiac arrest
This study tests whether using body cooling for different lengths of time helps children recover better after an out-of-hospital cardiac arrest. It focuses on children who remain very unresponsive after resuscitation and need a breathing tube and steady temperature control.
Birmingham, AlabamaAges 2 days–17 years - NCT05407480Recruiting
Treatment guidance study for children with Hodgkin lymphoma
This study is for children with “classical” Hodgkin lymphoma to help guide the best treatment plan. It may help your care team choose therapy based on what has worked for similar children.
Paris, FranceAges birth–18 years - NCT05367609Recruiting
Personalized pain plan for kids getting spine fusion surgery
This trial tests a personalized plan to manage pain around the time of pediatric posterior-lateral spinal fusion surgery. It aims to improve comfort and reduce the chance of pain or opioid problems after surgery by tailoring pain medicines to the child.
San Francisco, CaliforniaAges 10–21
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Common questions
- Are there clinical trials for pediatrics?
- Yes. Clin2 currently lists 1,359 recruiting pediatrics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pediatrics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pediatrics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.