Clinical trials
Pediatrics clinical trials
Below are recruiting pediatrics clinical trials, each written for real people, not researchers. We’re tracking 1,358 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04249375Recruiting
Using genetic testing to choose safer medicines for kids
This study helps doctors use genetic (pharmacogenomic) testing to choose which medicines may work best and cause fewer side effects. You may join if your child’s doctor is considering certain common medicines, such as pain, antibiotic, or mental health medications.
Vancouver, British ColumbiaAges Any age - NCT04185038RecruitingPhase 1
CAR T therapy through a catheter for pediatric brain tumors
This Phase 1 trial tests a personalized immune-cell treatment (CAR T) delivered directly in the brain-area space using a catheter. It may help children and young adults with hard-to-treat (recurrent or refractory) diffuse midline brain tumors like DIPG/DMG when standard options aren’t working.
Seattle, WashingtonAges 1–26 - NCT04094610RecruitingPhase 1/Phase 2
Repotrectinib for kids with certain cancer gene changes
This early-phase study tests repotrectinib, a targeted medicine, in children and young adults whose tumors have specific gene changes involving ROS1 or NTRK. It may help shrink advanced cancers that carry these gene alterations.
Los Angeles, CaliforniaAges Up to 25 years - NCT04065438Recruiting
Study of a blood-filter treatment for FSGS not responding to meds
This study looks at how well a specialized blood-filter device (the LIPOSORBER® LA-15) works for people with primary FSGS—especially when standard steroid and other medicines don’t work or can’t be tolerated. It may help reduce disease activity, particularly in people with kidney function that is still moderate or in those after kidney transplant.
Loma Linda, CaliforniaAges Up to 75 years - NCT04143724RecruitingPhase 2
Luspatercept for children with beta-thalassemia
This study tests a medicine called luspatercept to see if it safely helps children with beta-thalassemia need fewer blood transfusions or keep their hemoglobin levels stable. It is for children aged 6 to 17 who either get regular transfusions or have low hemoglobin and few transfusions.
Los Angeles, CaliforniaAges 6–17 - NCT04113382RecruitingPhase 1/Phase 2
A bowel prep study for children having a colonoscopy
This trial tests a bowel-cleansing liquid called CLENPIQ in children ages 1 to 9 who need a colonoscopy. It aims to see if it works well and is safe for preparing the colon before the procedure.
Mobile, AlabamaAges 1–8 - NCT04085887RecruitingPhase 1/Phase 2
Uses a targeted dye to help find brain tumors during surgery
This early-stage trial tests whether an injected medicine with a glowing dye (panitumumab-IRDye800) can help doctors better see pediatric brain tumors during planned surgery. If it works, it may help surgeons remove more tumor tissue safely.
Stanford, CaliforniaAges 6 months–25 years - NCT04077346Enrolling by invitation
Testing a brain-to-spine stimulation to help children step
This trial uses a noninvasive neuromodulation approach to stimulate the spinal walking circuits in children after spinal cord injury. It is meant to see whether the treatment can help a child practice stepping when they currently cannot stand or start walking.
Louisville, KentuckyAges 4–12 - NCT04112355Enrolling by invitation
Tracking children’s immune response after routine vaccinations
This study measures how a child’s immune system responds after standard childhood vaccines, like DTaP-IPV/Hib, pneumococcal, MMR, varicella, flu, and COVID shots. It may help researchers better understand what a “healthy” immune response looks like after vaccination.
Rochester, MinnesotaAges 4 months–21 years - NCT04098445Recruiting
Study of lung injury in children after stem cell transplant
This study follows children and teens who get a stem cell transplant to learn how lung problems develop over time. Your participation could help doctors better predict, prevent, and manage lung injury after transplant.
San Francisco, CaliforniaAges Up to 24 years - NCT04118712Recruiting
Ovarian tissue banking for girls and teens having ovary surgery
This study collects small pieces of ovarian tissue during certain surgeries in girls and teens (before or after puberty). The goal is to bank the tissue for possible future fertility or medical research.
Chicago, IllinoisAges Up to 18 years - NCT03325946Recruiting
Neuromotor research clinic for people with movement problems
This study is looking at people who have difficulties with movement or muscle control (neuromotor impairment). It may help researchers better understand these problems and improve future care.
Roanoke, VirginiaAges 3 months–18 years - NCT03986021Recruiting
How periods develop in young girls and women
This study looks at how the menstrual cycle matures in girls just starting their periods and in women with or without PCOS (a hormone condition). It may help doctors understand normal and abnormal cycles.
Research Triangle Park, North CarolinaAges 8–65 - NCT03934372RecruitingPhase 1/Phase 2
Ponatinib for children with relapsed or hard-to-treat cancers
This trial tests a targeted therapy called ponatinib in children whose leukemia, lymphoma, or solid tumor has come back or hasn't improved with standard treatments. The drug works by blocking signals that help cancer cells grow, and the study looks at how safe and effective it is for different cancer types.
GhentAges 1–17 - NCT03893045RecruitingPhase 3
Ferumoxytol for iron deficiency anemia in children
This trial tests ferumoxytol, an intravenous iron medicine, to treat iron deficiency anemia in children who cannot take or did not respond well to iron by mouth. It aims to improve blood iron levels and anemia symptoms safely.
Little Rock, ArkansasAges 2–17 - NCT03938987RecruitingPhase 1/Phase 2
CAR T-cell therapy for CD19-positive aggressive lymphoma or ALL
This trial tests a lab-made immune therapy (CAR T-cells) that targets CD19, a marker found on certain lymphoma and leukemia cells. It’s for people whose lymphoma or ALL came back or did not respond to standard treatments, with the goal of getting the treatment to attack the cancer.
Calgary, AlbertaAges 2–70 - NCT03959800Recruiting
Study of the causes of childhood liver tumors
This study looks at why childhood liver tumors happen by using samples and information from children who have had a liver tumor and from their close family members. It may help researchers understand the biology of these tumors and guide better treatments in the future.
Pittsburgh, PennsylvaniaAges birth–99 years - NCT03911388RecruitingPhase 1
HSV G207 for Children with Recurrent Cerebellar Brain Tumors
This trial is testing a virus called HSV G207, which is injected directly into the tumor, to treat children and young adults with a type of brain tumor in the cerebellum that has come back or not responded to standard treatments.
Birmingham, AlabamaAges 3–22 - NCT03831958Recruiting
Follow-up study of children cured of Cushing disease
This study checks long-term health in people who were treated successfully for Cushing disease when they were under 21. It also collects information from family members to study genetic links to pituitary tumors.
Bethesda, MarylandAges 2–90 - NCT03739827Recruiting
Study rare solid tumors and collect your health samples
This study follows people (and sometimes family members) connected to rare solid tumors and collects health information and samples (biospecimens). It helps researchers understand how these cancers develop and builds resources for future research, which may benefit you by contributing to better tailored care for rare cancers.
Bethesda, MarylandAges 4 weeks+ - NCT03731000Recruiting
Testing a glue-like treatment for abnormal brain vessel leaks in children
This trial studies a device that delivers a special “embolic” material (often described as glue) to treat a type of abnormal connection in the brain’s blood vessels (dAVF). It may help by blocking the leaking or risky blood flow, and it will be compared against how doctors handle eligible cases with other embolic materials.
New York, New YorkAges Up to 21 years - NCT03750513RecruitingPhase 1
Tested improved radiation targeting for children with ependymoma
This early-phase study tests a more precisely targeted type of radiation for children with ependymoma, aiming to treat the brain tumor more accurately. It may help reduce how much healthy tissue gets radiation, and researchers are checking safety and best dosing.
Boston, MassachusettsAges Up to 22 years - NCT03628612Enrolling by invitationPhase 2
Long-term follow-up after CAR T cell treatment
This study checks how people do over the long run after receiving a personalized, genetically modified CAR T cell treatment. It may help researchers understand long-term safety and outcomes, which can improve future care.
Miami, FloridaAges 1 year+ - NCT03619850RecruitingPhase 3
Ferumoxytol vs iron sucrose for child kidney anemia
This study compares two IV iron treatments—ferumoxytol and iron sucrose—to treat iron deficiency anemia in children with chronic kidney disease. It aims to see which option works better and is safe, and also to learn how each medicine behaves in the body.
Hollywood, FloridaAges 2–17
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Common questions
- Are there clinical trials for pediatrics?
- Yes. Clin2 currently lists 1,358 recruiting pediatrics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pediatrics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pediatrics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.