Clinical trials
Peptides clinical trials
Below are recruiting peptides clinical trials, each written for real people, not researchers. We’re tracking 139 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06741072RecruitingPhase 1
Vaccine to prevent EBV-related cancer in transplant patients
This trial tests a vaccine (OSU-2131) that may help prevent cancers caused by the Epstein-Barr virus in people waiting for an organ transplant. The vaccine is designed to train your immune system to fight the virus.
Columbus, OhioAges 18–65 - NCT06581120Enrolling by invitation
Stomach ultrasound study for diabetes and obesity
This study uses ultrasound to see how GLP-1 RA medications (like Ozempic) affect the stomach in people with type 2 diabetes and obesity. It may help doctors better understand how these medicines work.
Cincinnati, OhioAges 10–25 - NCT06564623RecruitingPhase 1
Peptide vaccine plus immunotherapy for biliary tract cancer
This trial tests a personalized peptide vaccine combined with two immunotherapy drugs (durvalumab and tremelimumab) for patients with biliary tract cancer whose tumors have specific genetic changes. The goal is to see if this combination can shrink tumors or slow their growth.
Baltimore, MarylandAges 18 years+ - NCT06510868Recruiting
MDS risk study for NET patients before or after PRRT
This study looks at the risk of developing Myelodysplastic Syndrome (MDS), a blood disorder, in people with Neuroendocrine Tumors (NET) who are treated with Peptide Radionuclide Therapy (PRRT). It involves a simple blood test to check for genetic changes linked to MDS. Participating can help understand and potentially prevent this side effect.
Toronto, OntarioAges Any age - NCT06470295RecruitingEarly Phase 1
C-peptide's effect on low blood sugar response
This study tests whether C-peptide (a substance made by the pancreas) can help your body respond better to low blood sugar (hypoglycemia). It's a very early trial for people without certain health conditions.
Cincinnati, OhioAges 18–40 - NCT06138236RecruitingEarly Phase 1
Comparing shockwave therapy and collagen for plantar fasciitis
This study tests whether shockwave therapy or collagen supplements work better for reducing heel pain from plantar fasciitis. If you have heel pain and haven't had foot surgery, you may be able to join.
BariAges 18–80 - NCT05950139RecruitingPhase 1/Phase 2
Vaccine to help stop lung cancer drug resistance
This early-phase study tests a personalized peptide vaccine designed to help prevent advanced ALK-positive non-small cell lung cancer from developing resistance to current targeted medicines. If you are stable on an ALK drug and don’t already have the specific resistance changes the vaccine targets, it may help your cancer stay controlled longer.
Baltimore, MarylandAges 18 years+ - NCT05879432RecruitingPhase 2
Peptide treatment to prevent or lessen kidney injury after heart surgery
This Phase 2 trial tests an LSALT peptide given around the time of “on-pump” heart surgery to help prevent or reduce acute kidney injury (a sudden drop in kidney function). It may help people who are at higher risk for kidney injury during or after surgery.
Calgary, AlbertaAges 18 years+ - NCT04248569RecruitingPhase 1
Vaccine plus immunotherapy for a specific liver cancer gene change
This Phase 1 trial tests a personalized peptide vaccine (targeting the DNAJB1-PRKACA fusion) combined with immunotherapy drugs to treat fibrolamellar hepatocellular carcinoma (FLC) or other eligible non-FLC cancers with the same gene fusion. It aims to see whether this immune-based treatment can shrink tumors and improve outcomes safely.
Baltimore, MarylandAges 12 years+ - NCT05741242Enrolling by invitationPhase 1/Phase 2
Vaccine trial using customized immune targets for solid tumors
This trial tests a personalized cancer vaccine made from synthetic long peptide “neoantigens,” aiming to be safe and help the immune system fight certain solid tumors. It may fit people with pancreatic cancer after starting first-line chemotherapy, and some other solid tumors with limited options.
Beverly Hills, CaliforniaAges 12 years+ - NCT05269381RecruitingPhase 1/Phase 2
Personalized cancer vaccine with pembrolizumab for advanced solid tumors
This trial tests a personalized vaccine made from your tumor's unique markers, combined with the drug pembrolizumab, to help your immune system fight cancer. It is for people with advanced solid tumors who have already tried standard treatments.
Jacksonville, FloridaAges 16 years+ - NCT05216042Recruiting
Study of genetics and heart/metabolic health in adults
This study looks at how genetic markers (DNA) relate to heart health and “metabolic” health (how your body manages sugar and fat). You may be asked to provide genetic samples and follow study health checks and protocols to help researchers understand who is at higher risk.
Birmingham, AlabamaAges 18 years+ - NCT05254184RecruitingPhase 1
Vaccine and immunotherapy for KRAS-mutated lung cancer
This Phase 1 study tests a KRAS-targeted vaccine combined with chemo and immunotherapy (nivolumab and ipilimumab) for people with advanced non-small cell lung cancer. It aims to help the immune system recognize and fight tumors with specific KRAS mutations, and to see if the treatment is safe and effective enough to study further.
Baltimore, MarylandAges 18–100 - NCT05098210RecruitingPhase 1
Personalized vaccine made from your tumor’s new immune targets
This Phase 1 study tests a customized vaccine made from “neo-antigens,” which are new targets found in your tumor. It aims to help your immune system fight certain advanced cancers that have not responded well to prior treatment.
Seattle, WashingtonAges 18 years+ - NCT04090034Recruiting
PRRT for advanced neuroendocrine tumors
This trial tests a treatment called PRRT, which delivers a radioactive medicine directly to tumor cells, for advanced neuroendocrine tumors. It may help those whose tumors are growing despite octreotide treatment, especially when scans show tumor uptake of specific tracers.
Dallas, TexasAges 18 years+ - NCT04055428RecruitingPhase 2
Testing a hormone supplement to improve heart and metabolic health
This study tests whether adding a natriuretic peptide medicine improves heart health and metabolism in Black adults. It may help with blood pressure and related health markers, but you must meet specific health and safety criteria.
Birmingham, AlabamaAges 18 years+ - NCT05691517RecruitingPhase 1
Test drug CBX-12 in advanced cancers and monitor your response
This Phase 1 study tests how your body handles the drug CBX-12 in people with advanced solid cancers that have already tried prior treatments. It may help researchers learn safe dosing and how tumors respond, and you may be asked to provide biopsy samples.
Bethesda, MarylandAges 18 years+ - NCT05919342Recruiting
Screening for early heart failure in primary care or at home
This trial tests whether simple screening using a blood test (natriuretic peptides) plus an ultrasound of the heart (echocardiogram) can find early heart failure sooner. Finding it earlier may help doctors start the right management to prevent it from getting worse.
Cleveland, OhioAges 40 years+ - NCT07860047RecruitingPhase 2
Peptide vaccine with antibody therapy for prostate cancer
This trial tests a combination of a personalized peptide vaccine and an antibody therapy for men with prostate cancer that has returned after initial treatment. The goal is to see if this approach can control the cancer without needing stronger hormone therapy.
Heidelberg, Baden-WurttembergAges 18–80 - NCT06451172RecruitingEarly Phase 1
New antibiotic eye drops for drug-resistant eye infections
This trial tests a new type of antibiotic eye drop for people with serious eye infections that don't respond to standard antibiotics. It aims to see if these drops can safely treat the infection and help improve vision.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07829328Enrolling by invitationPhase 4
Can a special rinse help prevent early cavities between teeth?
This trial tests a special rinse called SAP P11-4 to see if it can stop or reverse early cavities between teeth before they need fillings. It may help keep your teeth healthy without more involved dental work.
Schofield Barracks, HawaiiAges 18–74 - NCT06461377RecruitingPhase 4
GLP-1RA for heart nerve damage in type 2 diabetes
This trial tests whether a type of diabetes medicine called GLP-1RA can help prevent or improve nerve damage in the heart caused by diabetes. It is for people with type 2 diabetes who are overweight or obese.
Nanjing, JiangsuAges 18–70 - NCT07814248RecruitingPhase 1
TS-104 for advanced solid tumors
This trial tests a new drug called TS-104 for people with certain advanced solid tumors that have stopped responding to standard treatments. The drug is given alone (not with other cancer treatments) to see if it can shrink tumors or slow their growth.
Maumee, OhioAges 18 years+ - NCT07800481RecruitingEarly Phase 1
Imaging test for carotid artery health using a new tracer
This study tests a new imaging agent that may help see plaque buildup in the carotid arteries, which are the main arteries in the neck. It is looking for healthy volunteers to help establish a normal baseline for future scans.
St Louis, MissouriAges 18 years+
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Common questions
- Are there clinical trials for peptides?
- Yes. Clin2 currently lists 139 recruiting peptides studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a peptides trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a peptides trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.