Clinical trials
Perioperative clinical trials
Below are recruiting perioperative clinical trials, each written for real people, not researchers. We’re tracking 336 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06472063Recruiting
Surgery first vs chemo then surgery for advanced stomach cancer
This trial compares two approaches for stomach cancer that has spread a bit but can still be removed with surgery. One group has surgery first, the other gets chemotherapy before surgery. The goal is to see which sequence leads to better long-term outcomes.
Orbassano, PiedmontAges 18 years+ - NCT07586124RecruitingPhase 2
Immunotherapy plus antibody drug for advanced head and neck cancer
This trial tests a combination of two drugs (pucotenlimab and becotatug vedotin) given before surgery for advanced head and neck squamous cell carcinoma. The goal is to shrink tumors and improve outcomes when combined with surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06493227Recruiting
Extended use of bleeding control drugs after heart surgery
This trial is for hospitals, not patients. Hospitals that do many open heart surgeries and whose doctors agree to use certain bleeding control drugs (fibrinolysis inhibitors) as per the study protocol can participate.
Saint PetersburgAges 18 years+ - NCT06501079Recruiting
Pain relief study: adding dexamethasone or magnesium to a nerve block for kidney removal
This study compares two different medications (dexamethasone and magnesium) added to a standard painkiller used in a nerve block for patients having one kidney removed. The goal is to find out which combination provides better pain relief after surgery.
CairoAges 18–65 - NCT06510543Recruiting
Nutrition drink before and after esophageal cancer surgery
This study tests a special nutrition drink (ORAL IMPACT®) before and after esophageal cancer surgery. It aims to help patients who are malnourished get stronger and recover better.
Beijing, Beijing MunicipalityAges 18–80 - NCT06519747Recruiting
Detecting irregular heartbeat after non-heart surgery
This trial uses a monitoring device to check for a common but often overlooked irregular heartbeat (atrial fibrillation) after non-cardiac surgery. The goal is to detect and treat it early to prevent complications like stroke.
Hamilton, OntarioAges 18–120 - NCT06543134Recruiting
Body temperature and waking confusion after surgery
This study looks at how getting cold during surgery (hypothermia) might affect how confused or restless you feel when waking up from anesthesia. Researchers want to find ways to prevent these side effects and make your recovery smoother.
Kocaeli, IzmitAges 18–65 - NCT06560528RecruitingPhase 2
Drug combo before & after surgery for HER2+ stomach cancer
This trial tests a combination of three drugs (targeted therapy, immunotherapy, and chemotherapy) before and after surgery for locally advanced HER2-positive stomach cancer. It aims to see if this treatment can improve outcomes for patients whose cancer has not yet spread.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT06565052Recruiting
Exercise and nutrition before rectal cancer surgery study
This trial tests whether a personalized exercise and nutrition program before rectal cancer surgery can help you recover faster and have fewer complications. If you are not very active right now, you may be able to join.
Boston, MassachusettsAges 18 years+ - NCT06571396Recruiting
Surgery risks after immunotherapy for liver cancer
This study looks at the risks of surgery in people with liver cancer who received immunotherapy before or instead of surgery. It aims to understand how safe and effective this approach is.
Jinan, ShandongAges 18 years+ - NCT06575842Recruiting
Accuracy of glucose monitors during surgery in youth with type 1 diabetes
This trial tests how well continuous glucose monitors (CGMs) work during surgery and hospital stays in young people with type 1 diabetes. It aims to make sure these devices give accurate readings when they are most needed.
Aurora, ColoradoAges 2–26 - NCT06590714Recruiting
Polmacoxib for pain after rotator cuff surgery
This trial tests if Polmacoxib, an anti-inflammatory drug, can reduce the need for stronger painkillers after rotator cuff surgery. It may help manage pain with fewer side effects.
Uijeongbu-si, Gyeonggi-doAges 18 years+ - NCT06600815Recruiting
Step-by-step numbing shots for pain relief in knee replacement
This study tests whether a special step-by-step numbing injection given before knee replacement surgery can provide better pain relief during and after the procedure. It may help you have less pain and use fewer painkillers after surgery.
Fuzhou, FujianAges 18 years+ - NCT06615271Recruiting
Studying pressure injuries during and after brain surgery
This study looks at how often patients develop pressure injuries (sores from lying in one position too long) during long brain surgeries. It tracks patients before, during, and after surgery to find ways to prevent these injuries.
Santander, CantabriaAges 18–100 - NCT06639724RecruitingPhase 1
Test of fostamatinib with chemo before and after surgery for pancreatic cancer
This trial tests adding a new drug, fostamatinib, to standard chemotherapy before and after surgery for pancreatic cancer that can be removed. The goal is to see if the combination helps reduce the chance of cancer coming back.
La Jolla, CaliforniaAges 18 years+ - NCT06642129Recruiting
Study on spinal fluid pressure management in shunt surgery
This study watches how the pressure of spinal fluid around the brain and spine changes during surgery for communicating hydrocephalus. It aims to help doctors better manage a shunt that drains extra fluid from the lower back to the belly.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06655506Recruiting
Enhanced Recovery for Gynecologic Cancer Surgery
This trial studies whether an enhanced recovery after surgery (ERAS) program improves outcomes for people with gynecologic cancer. It aims to help you recover faster and with fewer complications.
Athens, AthensAges 25–85 - NCT06659042RecruitingPhase 2
Tislelizumab before and after surgery for KRAS-mutated lung cancer
This trial tests whether adding the immunotherapy drug tislelizumab before and after surgery can help people with a specific type of lung cancer (non-squamous NSCLC with a KRAS mutation) that is stage 2 or 3. It aims to improve treatment outcomes by targeting the cancer early.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06660602Recruiting
Brain function check before and after heart surgery
This study checks how well your brain works before and after heart surgery. It uses safe tests like a CT scan and an EEG to see if surgery affects brain function.
BeijingAges 18–80 - NCT06704451Recruiting
IL-33 and memory after major abdominal surgery
This study looks at whether a protein called IL-33 is linked to memory and thinking problems that can happen after major abdominal surgery. It may help doctors find patients at risk earlier.
Kunming, YunnanAges Any age - NCT06962007Recruiting
Jaw clenching after sugammadex for muscle relaxation reversal
This trial tests whether a drug called sugammadex, which reverses muscle relaxation from anesthesia, might cause jaw clenching in some people. The study will watch for this effect during routine surgery to better understand the risk.
Iksan, Jeonbuk-doAges 19–70 - NCT07552766RecruitingPhase 4
Lidocaine infusion to reduce opioid use in arm fracture surgery
This study tests whether giving a pain-relieving medication called lidocaine through an IV during arm fracture surgery can reduce how much opioid pain medication (like morphine) children need after surgery. The goal is to help manage pain better while using fewer opioids.
Wilmington, DelawareAges 3–18 - NCT06731998Recruiting
Improving pain control after cancer surgery
This study compares different methods of managing pain after minimally invasive surgery for abdominal cancers. It aims to find which approach works best to reduce pain and improve recovery.
Pittsburgh, PennsylvaniaAges 18–89 - NCT06732193Recruiting
Fissios App for recovery after lung cancer surgery
This trial tests whether using a smartphone app (Fissios) after lung cancer surgery helps you recover with fewer complications. If you are scheduled for lung surgery for non-small cell lung cancer and have a smartphone, you may be eligible.
Madrid, MadridAges 18 years+
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Common questions
- Are there clinical trials for perioperative?
- Yes. Clin2 currently lists 336 recruiting perioperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a perioperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a perioperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.