Clinical trials
Peripheral Artery Disease clinical trials
Below are recruiting peripheral artery disease clinical trials, each written for real people, not researchers. We’re tracking 224 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06033924Recruiting
Home Walking Program for Vets with Leg Artery Disease
This study tests a home-based walking program delivered through telehealth for Veterans with peripheral artery disease (PAD). It aims to help you walk farther with less pain.
Birmingham, AlabamaAges 21 years+ - NCT06041880Recruiting
Calf Stretching for Better Walking in PAD
This study tests whether a simple daily calf-stretching routine can improve walking ability and blood flow in people with peripheral artery disease. It offers a non-drug, non-surgical approach that you can do at home.
University Park, PennsylvaniaAges 40–85 - NCT06067789Recruiting
Testing spinal vs. general anesthesia for leg blood flow surgery
This study tests a new way to give anesthesia during leg surgery to improve blood flow. It aims to see if spinal anesthesia works better than general anesthesia for recovery and comfort.
Ottawa, OntarioAges 18 years+ - NCT06082466Recruiting
Comparing two types of leg bypass surgery
This study compares two types of bypass surgery for blocked leg arteries. One uses a standard vein from your own body, and the other uses a vein supported by a special metal frame. The goal is to see which works better and lasts longer.
SalzburgAges 18 years+ - NCT06215248Recruiting
Heart function study in leg artery disease patients
This trial uses ultrasound to check how well the heart pumps in people with blocked leg arteries. It aims to find early signs of heart strain that standard tests might miss.
TartuAges 35–85 - NCT06223217Recruiting
New quality-of-life survey for leg artery disease patients
This study tests a new questionnaire (modified VascuQol) to measure how leg artery disease affects your daily life. It aims to create a better tool for doctors to track your symptoms and well-being.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT06231966Recruiting
High-dose statin combo vs. standard statin for artery disease
This trial compares a high-dose combination of rosuvastatin (a statin) and ezetimibe (another cholesterol-lowering drug) versus a standard rosuvastatin-only approach for people with peripheral artery disease (narrowed leg arteries) or widespread artery disease. The goal is to see which strategy better lowers LDL cholesterol and reduces heart and limb risks.
SeoulAges 19–80 - NCT06250790Recruiting
Heart Artery Check for Leg Artery Disease Patients
This trial uses a special CT scan (coronary CTA with HeartFlow analysis) to look for hidden blockages in the heart arteries of people who recently had a leg artery procedure. It may help detect heart problems early so they can be treated.
RigaAges 50 years+ - NCT06253312Recruiting
Comparing treatments for severe pelvic artery blockages
This study looks back at adults treated for severe blockages in the large arteries of the pelvis and lower belly. Researchers want to compare how well different treatments (minimally invasive procedures, open surgery, or a mix) worked over time.
BelgradeAges 18–100 - NCT06275113Recruiting
Prevention program for heart and artery disease
This study tests a prevention program for people who have already had a heart event, stroke, or leg artery blockage. It is designed to help reduce the risk of future heart problems.
Canicattì, AGAges 18 years+ - NCT06300450Recruiting
Alert test for cholesterol meds in PAD patients
This study tests whether a special alert in your electronic health record can help doctors start the right cholesterol-lowering medication for people with peripheral artery disease (PAD) who are not already on one. The goal is to see if the alert helps get treatment started more often.
Boston, MassachusettsAges 18 years+ - NCT06308562Recruiting
Fuzzy sock after leg amputation to help healing
This trial tests a fuzzy compression sock worn on the leg after amputation below the knee (transtibial amputation). The goal is to see if it helps the wound heal better in people with peripheral artery disease.
Rochester, MinnesotaAges 18 years+ - NCT06318767Recruiting
Foot Blood Flow Measurements to Predict Limb and Heart Events
This study measures how blood flows through your foot using ultrasound to see if it can predict serious problems with your leg or heart in people with severe circulation problems. The goal is to find a simple test that helps doctors decide the best treatment for you.
AmiensAges 18 years+ - NCT06319339RecruitingEarly Phase 1
Studying a drug to improve walking in peripheral artery disease
This trial tests whether a drug called diroximel fumarate (Vumerity) can improve blood flow and walking ability in people with peripheral artery disease (PAD). It compares people with PAD to healthy volunteers of the same age.
Omaha, NebraskaAges 50–75 - NCT06399900Recruiting
Light therapy plus exercise for better walking with PAD
This study tests whether adding light therapy to a walking program helps people with peripheral artery disease (PAD) walk further and feel better. You'll receive either light therapy or a placebo light while doing a supervised exercise program.
Chicago, IllinoisAges 50 years+ - NCT06399809RecruitingPhase 2
Fisetin for better walking in peripheral artery disease
This study tests whether a supplement called fisetin can help reduce leg pain and improve walking ability in people with peripheral artery disease (PAD). If you have PAD and are 50 or older, you may be able to join and help see if fisetin can make walking easier.
Chicago, IllinoisAges 50 years+ - NCT06410521Recruiting
Personalized exercise program for peripheral arterial disease
This trial tests a personalized exercise program for people with peripheral arterial disease (PAD), a condition that causes leg pain when walking. The goal is to see if a tailored exercise plan can help reduce pain, improve walking distance, and boost quality of life.
Vila RealAges 18 years+ - NCT06420752RecruitingPhase 2
Passive stretching for peripheral artery disease
This study tests whether gentle leg stretching, done by a therapist, can improve blood flow and walking ability in people with peripheral artery disease (narrowed leg arteries). It may be an option for those who cannot do regular exercise.
La Crosse, WisconsinAges 40–90 - NCT06480760RecruitingPhase 1/Phase 2
Carnosine for peripheral arterial disease
This trial tests whether a natural supplement called carnosine can improve walking distance and blood flow in people with peripheral arterial disease (PAD). PAD is a narrowing of the leg arteries that can cause pain when walking.
Louisville, KentuckyAges 40–80 - NCT06480786Recruiting
Spinal cord stimulator for diabetic nerve and artery pain
This study tests if a spinal cord stimulator (a device that sends mild electrical pulses to the spine) can relieve severe leg pain caused by diabetic nerve damage and poor blood flow. It may help people who have not found enough relief from other treatments.
Omaha, NebraskaAges 19–89 - NCT06539689Recruiting
Sperstent for remaining blockages after balloon treatment in leg arteries
This trial tests a special stent called Sperstent for people who still have blockages or tears in their leg arteries after balloon treatment. It is designed to help improve blood flow and reduce symptoms like leg pain or sores.
Beijing, Beijing MunicipalityAges 18–85 - NCT06541691Recruiting
Aspirin for heart disease patients in polluted air
This study tests if different types of aspirin (coated or chewable) and a special schedule can help people with heart or blood vessel disease when they are exposed to air pollution. If you live in Tehran and have stable heart disease, you may be able to join.
Tehran, Tehran ProvinceAges 18 years+ - NCT06567795Recruiting
Monitoring heart risk with a wearable sensor in diabetes
This trial tests a wearable chest sensor (called HEMOTAG) to monitor heart events in people with long-standing Type 2 diabetes who also have heart disease or specific diabetes-related complications. The sensor is worn at home for short periods to catch early signs of heart trouble, aiming to improve personalized care.
West Palm Beach, FloridaAges 40 years+ - NCT06573437Recruiting
VESTO vascular stent for leg artery blockages
This study tests a new stent (a tiny mesh tube) to open blocked arteries in the pelvis or thigh area. It may help improve blood flow and reduce leg pain or wounds.
Salvador, Estado de BahiaAges 18 years+
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Common questions
- Are there clinical trials for peripheral artery disease?
- Yes. Clin2 currently lists 224 recruiting peripheral artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a peripheral artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a peripheral artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.