Clinical trials
Peripheral Neuropathy clinical trials
Below are recruiting peripheral neuropathy clinical trials, each written for real people, not researchers. We’re tracking 162 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06619860RecruitingPhase 2
VX-993 for diabetic nerve pain
This trial tests a new medicine called VX-993 for people with diabetes who have had nerve pain in both feet or legs for at least a year. The goal is to see if it reduces pain and is safe.
Cullman, AlabamaAges 18–80 - NCT06628908RecruitingPhase 3
Study of suzetrigine for painful diabetic nerve damage
This trial tests an experimental medicine called suzetrigine to see if it can safely reduce pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It might be an option if you have had daily pain in both legs and current treatments haven't worked well enough.
Anniston, AlabamaAges 18–80 - NCT07794475RecruitingPhase 1/Phase 2
Trimetazidine for diabetic nerve pain
This trial tests whether the drug trimetazidine can improve nerve damage symptoms in people with type 2 diabetes and diabetic neuropathy. It also looks at how the drug affects a substance in the blood called endothelin-1, which may be involved in nerve damage.
CairoAges 18–65 - NCT06201611RecruitingPhase 2/Phase 3
Nebivolol for diabetic nerve damage study
This study tests whether the drug nebivolol (a type of beta-blocker) can help slow or reverse nerve damage caused by diabetes. It is for people with recent diabetes and confirmed neuropathy.
Bangalore, KarnatakaAges Up to 18 years - NCT05980767Recruiting
Electrical stimulation for better recovery after cubital tunnel release
This trial tests a short burst of electrical stimulation during surgery to improve nerve healing and hand function after cubital tunnel release. It may help people with ulnar nerve problems at the elbow recover faster.
Hamilton, OntarioAges 18–80 - NCT07827417Recruiting
Balance training for diabetic nerve pain
This study compares two types of exercise to help improve balance in people with diabetic peripheral neuropathy. You may join if you have diabetes-related nerve damage and trouble with balance.
IslamabadAges 40 years+ - NCT04699734Recruiting
Nerve block for nerve pain from diabetes
This trial studies whether a numbing “nerve block” can reduce long-lasting nerve pain caused by diabetic neuropathy. You may keep your usual pain medicines, and the study will mainly check whether you fit the safety and diagnosis criteria.
Aarhus N, JutlandAges 18 years+ - NCT07260656RecruitingEarly Phase 1
Capsaicin cream for diabetic nerve foot pain
This trial tests a new cream (Capsadyn®) made from chili pepper extract to see if it can reduce nerve pain in the feet caused by diabetes. If it works, it could offer a simple treatment you apply at home.
Roanoke, VirginiaAges 25–75 - NCT06834685Recruiting
Laser therapy for nerve pain after chemotherapy
This study tests a special laser treatment (photobiomodulation) to reduce nerve pain caused by chemotherapy in cancer patients. If you have had nerve pain for at least 3 months after chemo and can attend twice-weekly sessions, this may help ease your pain.
Mougins, Alpes MaritimesAges 18 years+ - NCT06158529Recruiting
High-frequency spinal cord stimulation for diabetic nerve pain
This trial tests if a special type of spinal cord stimulation (high-frequency SCS) can better relieve painful nerve damage caused by diabetes. If you have long-term burning, stabbing, or electric-shock-like pain in both legs, this treatment may help reduce that pain.
BeijingAges 18–80 - NCT07712913RecruitingPhase 3
Pregabalin for nerve pain from diabetes or shingles
This trial tests an extended-release version of pregabalin (a pain medication) for people with long-term nerve pain caused by diabetes or shingles. It aims to see if this once-daily pill can reduce pain with fewer side effects.
Salvador, Estado de BahiaAges 18–75 - NCT07661667Enrolling by invitation
Laser therapy for nerve damage from anti-MAG antibodies
This study tests whether a specific type of light therapy (photobiomodulation) can improve symptoms of nerve damage (peripheral neuropathy) caused by anti-MAG antibodies. If you have this condition, this trial might offer a new way to manage your symptoms.
QuimperAges 18 years+ - NCT06799351RecruitingPhase 2/Phase 3
Gut bacteria and nerve pain after chemo
This study looks at how bacteria in your gut (microbiome) might be linked to nerve pain from chemotherapy. It is for people who are already in the OzoParQT trial and will provide a stool sample to help understand this connection.
Las Palmas, Las PalmasAges 18 years+ - NCT02610439Recruiting
Genetic testing to find causes of paclitaxel nerve damage
This study uses genetic tests on blood DNA to look for differences that may explain why some people develop nerve pain (peripheral neuropathy) from paclitaxel used for breast cancer. It compares people who got significant neuropathy during treatment with people who did not get neuropathy after completing paclitaxel.
Boston, MassachusettsAges Any age - NCT05928429Recruiting
Cold treatment to prevent nerve pain from weekly paclitaxel
This trial tests whether cryotherapy (cooling the hands/feet during chemo) can prevent or lessen nerve pain caused by paclitaxel in people with early breast cancer. It may help you stay more comfortable and function better during treatment.
CopenhagenAges 18 years+ - NCT07160270Recruiting
Nerve problems in Waldenström's macroglobulinemia
This study looks at how common nerve problems (peripheral neuropathy) are in people with Waldenström's macroglobulinemia (WM), and how to best diagnose them. It aims to help doctors find nerve issues earlier and improve care.
København ØAges Any age - NCT07405021Recruiting
Vagus nerve stimulation for diabetic nerve pain
This trial tests whether using a non-invasive device to stimulate the vagus nerve can reduce nerve pain and improve function in people with diabetic neuropathy. It may be a good option if you have burning or electric-shock-like foot pain despite standard diabetes care.
DamiettaAges 45–60 - NCT07391995Recruiting
New test for germs in diabetic foot bone infections
This study tests a new device that quickly identifies the germs in foot wounds of people with diabetes and bone infections. It may help doctors choose the right antibiotic faster.
Nîmes, GardAges Any age - NCT07387653Recruiting
Leg circulation monitoring during pelvic surgery
This trial tests a new way to check blood flow and oxygen levels in your legs during pelvic surgery when you're in the lithotomy (legs-up) position. It aims to catch any circulation problems early, which could help prevent leg injuries.
Houston, TexasAges Any age - NCT07377279Recruiting
Acupuncture and compression to prevent nerve pain from chemo
This trial tests whether acupuncture and compression therapy can prevent nerve damage caused by taxane chemotherapy in early-stage breast cancer. It aims to reduce numbness, tingling, or pain in the hands and feet.
Guangzhou, GuangdongAges 18–70 - NCT07326930Recruiting
Nerve changes in children with leukemia during chemotherapy
This study tracks how chemotherapy affects nerves in children aged 8 to 17 with acute lymphoblastic leukemia. It aims to understand who may experience nerve problems, helping doctors better manage symptoms.
Zhengzhou, HenanAges 8–17 - NCT07325851Recruiting
Ozone therapy for chronic pain when other options fail
This study is testing ozone therapy as a palliative treatment for people with chronic pain who haven't found relief from other options. It aims to see if adding ozone can improve pain and quality of life.
Las Palmas de Gran Canaria, Las PalmasAges 18 years+ - NCT07301892Recruiting
AI help for rheumatoid arthritis diagnosis
This trial tests whether artificial intelligence (AI) can improve how doctors spot complications in people newly diagnosed with rheumatoid arthritis (RA), a condition that causes joint pain and swelling. The goal is to see if AI can make diagnosis faster and more accurate in real-world hospital settings.
Beijing, Beijing MunicipalityAges Any age - NCT07268833Recruiting
Finding new ALS biomarkers from nerve cells and blood
This study looks for new ways to detect and understand ALS by analyzing tiny nerve and blood markers. It may help find better treatments for ALS and related nerve diseases.
Monserrato, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for peripheral neuropathy?
- Yes. Clin2 currently lists 162 recruiting peripheral neuropathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a peripheral neuropathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a peripheral neuropathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Chemotherapy-induced Peripheral Neuropathy
- Diabetic Peripheral Neuropathy
- Peripheral Neuropathy Due to Chemotherapy
- Peripheral Neuropathy With Type 2 Diabetes
- Paclitaxel-induced Peripheral Neuropathy
- Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients
- Taxane-induced Peripheral Neuropathy
- Peripheral Arterial Disease
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.