Clinical trials
Peripheral Neuropathy clinical trials
Below are recruiting peripheral neuropathy clinical trials, each written for real people, not researchers. We’re tracking 162 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05950659Recruiting
Wearable insoles to prevent repeat diabetic foot ulcers
This trial tests special sensory insoles (called Orpyx Sensory Insoles) to help prevent diabetic foot ulcers from coming back. It aims to reduce high-pressure foot spots for people who already had a healed nerve-related ulcer.
Baltimore, MarylandAges 18 years+ - NCT04257877Recruiting
Studying blood proteins in children with type 1 diabetes
This study looks at blood protein patterns in children with type 1 diabetes to better understand the condition. It may help researchers find markers linked to how diabetes is doing, especially in young, early-stage children.
ThessalonikiAges 5–10 - NCT04415892Recruiting
Studying a therapy target for nerve pain after chemotherapy
This study looks at “TRP channels,” which are part of how nerves sense pain and temperature, to understand nerve pain (neuropathy) after chemotherapy. It may help improve how future treatments prevent or reduce nerve pain in people who have had certain chemotherapy drugs.
Leuven, Vlaams-BrabantAges 18–75 - NCT04652609Recruiting
Exercise program to prevent nerve damage from chemotherapy
This trial studies an exercise program (PRESIONA) that may help prevent nerve pain or numbness caused by a common type of breast cancer chemotherapy called taxane-based treatment. It targets people with HER2-positive breast cancer who are about to start neoadjuvant chemotherapy.
GranadaAges 18–70 - NCT04909138Recruiting
Intermittent nerve stimulation instead of daily low-frequency therapy
This study tests whether switching from continuous implanted nerve stimulation to an intermittent schedule can keep pain relief for people with chronic back and/or leg pain. You would be compared in a structured study plan to see if the alternate dosing works for you and is safe.
Chicago, IllinoisAges 18–90 - NCT05152368RecruitingPhase 1
Tested umbilical cord stem cell exosomes for trigeminal nerve pain
This Phase 1 study tests whether a treatment made from donated umbilical cord stem cell “exosomes” is safe for people with trigeminal neuralgia (severe facial nerve pain). It mainly focuses on safety and tolerability, and it may help by calming nerve-related pain pathways.
St John'sAges Any age - NCT05237973Recruiting
Neuromuscular ultrasound study for healthy people and patients
This study uses an ultrasound scan to look at muscles and nerves (including the breathing muscle). It may help researchers better understand neuromuscular problems and how well ultrasound can detect them.
Bethesda, MarylandAges 18–110 - NCT05295498Recruiting
Brain stimulation trial for nerve pain relief
This trial studies whether repeated magnetic stimulation of the brain can reduce ongoing nerve pain. It may help people whose nerve pain has been steady for at least a month and who still need pain medicine more than once a week.
KrakowAges 18 years+ - NCT05341141Recruiting
Cold therapy plus compression to prevent nerve damage from chemo
This trial tests whether using cold therapy (cryotherapy) together with compression can lower the chance of numbness, tingling, or pain in the hands and feet caused by chemotherapy. It may help people planning chemotherapy for breast cancer stay more comfortable and function better.
Beijing, Beijing MunicipalityAges 20–70 - NCT05404230Recruiting
Preventing nerve damage from oxaliplatin in the hands and feet
This study looks at ways to prevent numbness or nerve pain in the hands and feet that can happen from oxaliplatin treatment. It includes people with colon or rectal cancer who will be getting standard chemotherapy with capecitabine plus oxaliplatin.
AalborgAges 18 years+ - NCT05417737Recruiting
Ozone therapy for chronic pain when standard treatments fail
This study offers a palliative (comfort-focused) ozone treatment to adults with chronic pain when usual treatments don’t work or are too risky. Researchers will check whether adding ozone can help symptoms and whether it’s safe for selected patients.
Las Palmas, Las PalmasAges 18 years+ - NCT05710809Recruiting
Exercise and health check study for older colorectal cancer patients
This trial looks at sarcopenia (loss of muscle strength/size) and vertigo (feeling dizzy or off-balance) in older adults with colorectal cancer. It tests whether a structured, exercise-based approach can help these issues alongside cancer care.
CopenhagenAges 65 years+ - NCT05850130Recruiting
Acupuncture to treat nerve pain from oxaliplatin chemotherapy
This study tests whether acupuncture can reduce nerve pain caused by oxaliplatin chemotherapy in people with gastrointestinal cancers. It may help lessen symptoms like tingling, numbness, or burning that affect hands or feet.
CréteilAges 18 years+ - NCT06052345Recruiting
Nerve damage from paclitaxel in breast cancer patients
This study looks at how paclitaxel chemotherapy may affect the nerves in the hands and feet (peripheral neuropathy) in women with early breast cancer. It aims to find early signs of nerve damage, understand risk factors, and track how it impacts your daily life and lifestyle.
Solna, Stockholm CountyAges 18 years+ - NCT06127264Recruiting
Testing force in a carbon fiber leg brace cuff
This study tests how well a sensor measures force in the top part of a carbon fiber leg brace. It may help improve brace design for people who need them.
Iowa City, IowaAges 18–90 - NCT06343558Recruiting
Gait and balance study for rare neurological diseases
This study looks at how people with rare or common neurological diseases walk and keep their balance. You will be asked to do simple walking and standing tasks to help doctors understand these problems better.
Milan, MilanAges 18–80 - NCT06657157Recruiting
Nerve side effects study for new bladder cancer treatment
This study watches for nerve problems in people getting enfortumab vedotin and pembrolizumab as their first treatment for advanced bladder cancer. It aims to understand how common these side effects are and how they affect patients.
Augsburg, BavariaAges 18 years+ - NCT06772935Recruiting
Acupuncture for nerve pain from breast cancer chemo
This trial tests if electroacupuncture can help with nerve pain or numbness caused by taxane chemotherapy for breast cancer. It may offer relief for ongoing symptoms after treatment.
Xining, QinghaiAges 18–75 - NCT06856447RecruitingPhase 1
Coenzyme Q10 to prevent nerve damage from chemotherapy
This trial tests whether taking coenzyme Q10 (a natural substance) can help prevent nerve damage caused by the chemotherapy drug oxaliplatin in people with stage III colorectal cancer. If successful, it could reduce pain, numbness, or tingling during treatment.
CairoAges 18 years+ - NCT06933108Recruiting
Predicting Nerve Damage with Simple Function Tests
This study looks at whether simple function tests can predict nerve damage in people with advanced kidney disease or diabetes. It aims to find early signs of nerve problems before they become serious.
Le MansAges 60–80 - NCT06977035Recruiting
Nerve study for arthritis patients on baricitinib
This trial checks how the medication baricitinib affects nerves in people with rheumatoid arthritis. It uses a nerve test to see if the drug causes nerve problems.
SohagAges 18–65 - NCT06980948RecruitingPhase 1/Phase 2
Gene therapy study for nerve pain from small fiber neuropathy
This trial tests a new gene therapy called ST-503 for people with long-lasting nerve pain from small fiber neuropathy that hasn't improved with standard treatments. The study will check if the treatment is safe and tolerable.
Scottsdale, ArizonaAges 18 years+ - NCT07072468RecruitingPhase 2
Test of a gel for nerve pain after chemotherapy
This study tests a new gel (VMD-3866) applied to the skin to treat moderate nerve pain, numbness, or tingling caused by previous chemotherapy. It aims to see if the gel can safely reduce pain for people whose symptoms have been stable for at least 8 weeks.
London, UKAges 18–80 - NCT07092111Recruiting
Ear acupuncture to prevent nerve damage from chemotherapy in breast cancer
This trial tests if ear acupuncture can help prevent nerve damage caused by taxane chemotherapy in breast cancer patients. If you are starting 4 rounds of this chemo and have not had nerve issues before, this may be an option for you.
Nanjing, JiangsuAges 18–75
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Common questions
- Are there clinical trials for peripheral neuropathy?
- Yes. Clin2 currently lists 162 recruiting peripheral neuropathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a peripheral neuropathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a peripheral neuropathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Chemotherapy-induced Peripheral Neuropathy
- Diabetic Peripheral Neuropathy
- Peripheral Neuropathy Due to Chemotherapy
- Peripheral Neuropathy With Type 2 Diabetes
- Paclitaxel-induced Peripheral Neuropathy
- Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients
- Taxane-induced Peripheral Neuropathy
- Peripheral Arterial Disease
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.