Clinical trials
Pilot Study clinical trials
Below are recruiting pilot study clinical trials, each written for real people, not researchers. We’re tracking 508 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04428515Recruiting
Photoacoustic scans for untreated head and neck cancer
This study tests a special imaging scan (photoacoustic imaging) to help doctors look at head and neck cancer before treatment. It’s for people who have not had first-line therapy yet and will be starting radiotherapy.
Toronto, OntarioAges Any age - NCT04512716RecruitingEarly Phase 1
Radioimmunotherapy then CD19 CAR T for hard-to-treat blood cancers
This early-phase study tests a two-step treatment: first a targeted radioactive antibody (131-I apamistamab) and then CD19 CAR T-cell therapy. It is for adults with relapsed or refractory B-cell acute lymphoblastic leukemia (B-ALL) or diffuse large B-cell lymphoma (DLBCL) that is not responding or has come back, aiming to shrink cancer using engineered immune cells.
Basking Ridge, New JerseyAges 18 years+ - NCT04571736Recruiting
Web and video support during thyroid surgery planning
This study tests a pre-surgery video support program and a secure website to help people prepare for thyroid surgery. It may improve understanding and follow-through by collecting your answers before the operation.
Montpellier, HéraultAges 18–75 - NCT04655404RecruitingEarly Phase 1
Larotrectinib for children with newly diagnosed glioma with NTRK fusion
This trial tests larotrectinib, a targeted cancer medicine, in children and teens with newly diagnosed high-grade brain glioma that has an NTRK fusion. It may help shrink or control tumors by targeting a specific genetic change in the cancer.
Aurora, ColoradoAges Up to 21 years - NCT04701723Recruiting
Breathing training to help after trauma stress
This pilot study tests whether “cardiac coherence” breathing exercises can help prevent ongoing (chronic) post-traumatic stress disorder after a recent traumatic event. It’s meant for people who are newly dealing with an acute stress reaction, soon after the event.
Saint-PaulAges 18 years+ - NCT04722029RecruitingPhase 1/Phase 2
Donor immune-cell therapy for stubborn adenovirus infections
This study tests whether specially matched donor T-cells can control “refractory” adenovirus (a virus) that isn’t responding to usual antiviral medicines. It may help if the infection keeps coming back or is already affecting organs like the lungs or bowel.
Columbus, OhioAges Up to 60 years - NCT04746820Recruiting
Brain monitoring in unconscious ICU patients after cardiac arrest
This trial tests a bedside brain-monitoring method (near-infrared light and EEG) in people who are unconscious after severe brain injury from cardiac arrest. The goal is to see whether it can help measure brain function during the first week after admission.
Zurich, Canton of ZurichAges 18 years+ - NCT04770025RecruitingPhase 2
Brain stimulation with therapy for risky alcohol use
This study tests whether a non-invasive brain stimulation device can make standard psychotherapy work better for people who drink in a risky way. It’s designed for community participants who are not already in alcohol-use treatment.
Albuquerque, New MexicoAges 21–60 - NCT04771507RecruitingPhase 1/Phase 2
Testing intermittent ibrutinib for advanced chronic lymphocytic leukemia
This trial studies whether taking ibrutinib in a less continuous (“intermittent”) schedule can keep your chronic lymphocytic leukemia (CLL) under control. It’s for people who have already received ibrutinib for at least 6 months and had a good early response, aiming to reduce treatment intensity while tracking safety and cancer control.
TrondheimAges 18 years+ - NCT04783103Recruiting
Brain scan study of stimulation for depression in older adults
This is a pilot study that uses brain imaging to see how a brain “neuromodulation” approach may affect depression in people age 65 and older. You would be screened for depression severity, medication history, and safety limits, and then be asked to keep your depression medicines stable during the study.
Jette, Brussels CapitalAges 65 years+ - NCT04814420Recruiting
Study heart scarring in sleep apnea, with or without atrial fibrillation
This pilot study looks at whether obstructive sleep apnea leads to heart scarring (called atrial fibrosis), especially in people with and without an irregular heart rhythm (atrial fibrillation). It may help researchers understand who is at higher risk and why, using sleep testing and heart imaging.
New Orleans, LouisianaAges 18–75 - NCT04886245Recruiting
Eye-tracking study of face attention in facial paralysis
This pilot study uses an eye-tracking camera to measure where people look when viewing faces. It compares attention patterns in adults with facial paralysis to healthy adults, which may help improve understanding and support for people affected.
AmiensAges 18 years+ - NCT07145866RecruitingPhase 4
Varenicline and TMS for quitting nicotine use
This study tests whether combining the medication varenicline (Chantix) with a special brain stimulation treatment (TMS) can help people quit vaping or smoking nicotine. If you're motivated to quit and use nicotine daily, you may be able to join.
Boston, MassachusettsAges 18–65 - NCT07555548Recruiting
At-home external catheter study for women with recurrent catheter problems
This study tests whether PureWick, an external catheter device (worn outside the body rather than inserted), can reduce problems women experience with traditional indwelling catheters. If you've had repeated catheter issues requiring medical visits, this trial may help you avoid those complications.
DoncasterAges 18 years+ - NCT04947657Recruiting
Atrial fibrillation blood and heart scan pilot during ablation
This study looks at blood-related “clotting” signs and heart scan results in people with atrial fibrillation (AF) who are getting a catheter ablation. It may help doctors better understand AF and choose treatments more precisely.
New Orleans, LouisianaAges 18–120 - NCT05058846Recruiting
Pancreatic cancer screening for people with high-risk genes
This study checks whether regular pancreatic screening (likely including imaging) can find pancreatic cancer early in people with certain inherited gene changes and a family history. If you qualify, you may help doctors learn the best way to screen higher-risk people.
San Francisco, CaliforniaAges 18 years+ - NCT05093075RecruitingPhase 2
Plasma exchange for ICU patients with severe septic shock
This study tests whether therapeutic plasma exchange (a procedure that removes and replaces blood plasma) can improve outcomes in ICU patients with septic shock that is not responding to standard medicines. It may help some people whose infection-related illness is causing failing organs.
Calgary, AlbertaAges 16 years+ - NCT05151822Recruiting
Virtual reality during awake orthopedic or brain surgery
This pilot study tests whether a virtual reality (VR) headset can be used safely while you have certain types of surgery while you are awake or lightly sedated with local numbing. The goal is to see if VR can fit into surgery care for appropriate patients.
BrestAges 18–75 - NCT05171244Recruiting
Virtual reality training for kids with autism
This study tests whether immersive virtual reality (VR) training can improve how children with autism process different sensory information (like sights and sounds). It will compare children who do the VR training with another group as part of a pilot study at a child psychiatry center.
Tours, ToursAges 8–16 - NCT05217160RecruitingPhase 4
KeraStat gel with morphine for non-healing painful open wounds
This study tests whether KeraStat® gel that delivers morphine through the skin can reduce pain and help manage non-healing ulcers or open wounds. You may be eligible if your wound fits specific size and depth limits and you can track pain every day.
San Antonio, TexasAges 18 years+ - NCT05221359Recruiting
Safety trial of ExOlin® for adults with hard-to-control type 1 diabetes
This trial checks whether ExOlin® is safe in adults with type 1 diabetes who have had difficult blood sugar control or injection-site skin problems despite insulin pump and continuous glucose monitoring. It’s mainly looking for safety and comfort while using the treatment devices.
StrasbourgAges 18 years+ - NCT05290857Recruiting
Restarting blood thinners after a serious stomach bleed
This study follows people who had a serious, non-surgical stomach/intestine bleed while taking a blood thinner, and looks at when and how they restart a DOAC (a type of blood thinner). It may help your care team reduce the risk of another bleed while still preventing stroke or blood clots.
Calgary, AlbertaAges 18 years+ - NCT05319509Recruiting
Virtual reality therapy for anxiety in public health students
This pilot study tests whether guided virtual reality sessions can reduce anxiety symptoms in eligible students. You may be asked to complete brief anxiety screening and use the VR therapy if you qualify.
Houston, TexasAges 18–30 - NCT05389098Recruiting
Finger foods program to help eating in frail seniors
This study tests whether offering easy “finger foods” can improve eating and independence in older adults living in assisted care. It is looking especially at people who are losing weight, have low muscle strength, and may struggle to chew or swallow.
Château-RenaultAges 75–120
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Common questions
- Are there clinical trials for pilot study?
- Yes. Clin2 currently lists 508 recruiting pilot study studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pilot study trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pilot study trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.