Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,962 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04987775RecruitingEarly Phase 1
Study of NAC for Gulf War illness in veterans
This early-stage study tests the treatment called NAC to understand how it may work in veterans with Gulf War illness–related symptoms like fatigue and brain/mood changes. It also looks at “mechanisms,” meaning what’s happening in the body and brain while you’re in the study.
Palo Alto, CaliforniaAges 47–70 - NCT04990713Recruiting
Compare two pain-blocking methods during lung surgery
This study tests two different ways of numbing the chest to reduce pain during video-assisted lung surgery (VATS). It may help some people have less pain after surgery while still allowing the surgeon to do the operation safely.
London, OntairoAges 18 years+ - NCT04996017RecruitingPhase 3
Atezolizumab after surgery for malignant pleural mesothelioma
This study tests whether atezolizumab given after surgery and chemotherapy can lower the risk of mesothelioma coming back compared with a placebo. It may help by boosting the immune system to control remaining microscopic cancer cells.
Meldola, ITAòYAges 18 years+ - NCT04997733RecruitingPhase 3
Stool transplant to maintain Crohn’s remission after stopping anti-TNF
This Phase 3 study tests whether transplanting stool bacteria can help people with Crohn’s stay in remission after they stop an anti-TNF medicine. It may help some patients who are currently doing well but need to come off anti-TNF treatment.
ParisAges 18–74 - NCT04998188Recruiting
Hydrolyzed collagen for one knee with osteoarthritis
This trial tests whether a hydrolyzed collagen drink or supplement can reduce knee pain and symptoms compared with a placebo (inactive treatment) in people with osteoarthritis. It may help if you’ve tried standard non-surgical treatments and still have ongoing knee trouble.
BolognaAges 18–75 - NCT05005793RecruitingPhase 4
Alkali treatment to improve kidney graft blood vessel function
This trial tests whether adding an “alkali” treatment (to raise low blood bicarbonate) can improve blood vessel and kidney graft function in people whose kidney transplant is about 1 year old. It may help if you have lower-than-normal bicarbonate levels while on stable transplant and blood pressure medicines.
Aurora, ColoradoAges 18–80 - NCT05004727RecruitingPhase 4
Study for a psoriasis medicine in adults
This trial studies how guselkumab works for people with long-lasting, more severe psoriasis and signs that may affect joints. It may help by improving psoriasis symptoms and possibly reducing related inflammation, while researchers track safety and outcomes.
Boston, MassachusettsAges 18 years+ - NCT05004987RecruitingPhase 4
Study brain and blood changes in older adults with depression
This study looks at how a brain protein linked to Alzheimer’s disease changes over time in older adults who have major depression but no major memory problems. It involves brain scans, blood and urine tests, and a spinal fluid sample to better understand the connection between depression and brain aging.
New York, New YorkAges 60 years+ - NCT05006430RecruitingPhase 1/Phase 2
Fecal transplant study for severe alcoholic hepatitis safety
This trial tests whether fecal microbiota transplantation (a controlled transfer of stool bacteria) is safe in people with severe alcoholic hepatitis. It aims to see if the treatment is tolerable and what risks may come with it, in addition to watching how liver illness changes.
Houston, TexasAges 18–75 - NCT05008705Recruiting
Protein and muscle stimulation for hospitalized seniors
This trial tests whether increasing protein intake plus using a gentle electrical muscle stimulation device can help maintain or build muscle mass in older adults while they are hospitalized. It may help prevent muscle loss that can happen after short hospital stays.
São PauloAges 65 years+ - NCT05010148RecruitingPhase 3
IV lidocaine after spinal fusion to reduce delirium and pain
This trial tests whether giving lidocaine through a vein after elective spinal fusion surgery can help prevent confusion (delirium) and reduce pain. It may help people recover more comfortably and think more clearly after surgery.
San Francisco, CaliforniaAges 60 years+ - NCT05011266RecruitingPhase 2/Phase 3
Buprenorphine plus naltrexone shot to prevent opioid relapse
This trial tests whether a combination of buprenorphine (through your care plan) and a monthly extended-release naltrexone (XR-NTX) shot can help prevent opioid relapse. It may help people who are ready to move toward a naltrexone-based relapse-prevention treatment after detox.
Rockville, MarylandAges 18–65 - NCT05015439RecruitingPhase 1
CBD study for adults with autism and challenging symptoms
This Phase 1 study tests cannabidiol (CBD) in adults on the autism spectrum who also have mood, sleep, or behavior problems. The goal is to learn whether CBD can be given safely and may help symptoms that affect daily life.
Baltimore, MarylandAges 18 years+ - NCT05016219Recruiting
Light therapy to improve sleep and thinking in early Alzheimer’s
This trial studies rhythmic light therapy to help people with early Alzheimer’s or mild memory problems, especially when sleep is getting worse. If you fit the sleep and vision/medical safety requirements, the study may see whether the therapy improves sleep and thinking-related symptoms.
Menands, New YorkAges 55 years+ - NCT05018221RecruitingPhase 3
Testing better treatment information for calciphylaxis ulcers
This Phase 3 study is for adults on regular dialysis who have a new calciphylaxis ulcer. It tests a better way to give and use treatment guidance so ulcers may improve with clearer, more consistent care.
Concord, New South WalesAges 18 years+ - NCT05018481RecruitingEarly Phase 1
Study for moderate alcoholic hepatitis after heavy drinking
This early-phase study is testing a treatment approach for people with alcoholic hepatitis (liver inflammation caused by heavy alcohol use). It may help by improving liver function and outcomes in people who meet specific lab and health criteria.
Cleveland, OhioAges 21–65 - NCT05027919RecruitingPhase 2
Testing ways to predict opioid withdrawal during a taper
This Phase 2 study looks at what opioid withdrawal looks like in the body and whether they can measure it in a meaningful way. You may join if you have an opioid use disorder, can show physical dependence, and are interested in tapering (gradually reducing) opioids under study care.
Baltimore, MarylandAges 18–65 - NCT05028153RecruitingPhase 2
Azithromycin for young children with asthma-like hospital symptoms
This trial tests whether the antibiotic azithromycin can help children in the hospital who are having asthma-like breathing symptoms. If you qualify, your child may get azithromycin as part of the study and will be monitored closely for side effects and breathing improvement.
Gentofte MunicipalityAges 1 year–5.9 years - NCT05028140RecruitingPhase 3
Testing a lifestyle-and-diet program for type 2 diabetes control
This Phase 3 study tests whether a program run by the Piemonte Association can improve blood sugar control in people with type 2 diabetes who haven’t reached their target after usual diet, exercise, and stable medicines. It also aims to check that the approach is safe for participants.
Hortolândia, São PauloAges 18–85 - NCT05038462Recruiting
Fetal care study for babies with slow growth
This study looks at therapies meant to support brain development in babies whose growth is slower than expected before birth. It enrolls pregnancies in a specific time window and uses ultrasound/Doppler testing to make sure the baby is not likely needing delivery immediately.
BarcelonaAges 18 years+ - NCT05043116RecruitingPhase 2
Vitamin D for preventing asthma-like flare-ups in young children
This study tests whether a high-dose vitamin D supplement can help preschool children have fewer acute asthma-like symptoms (coughing, wheezing, or trouble breathing) that require hospital care. It may help by supporting the immune and airway system, but you can only join if the child meets several safety and treatment criteria.
Gentofte Municipality, GentofteAges 1 year–5.9 years - NCT05049057RecruitingPhase 2
Testing a nerve-blocking shot for recent mild TBI
This Phase 2 study tests a medication that blocks a pain signal (a CGRP receptor antibody) in people who recently had a mild traumatic brain injury (mTBI) and are also dealing with post-traumatic headache (PTH). The goal is to see if it can reduce symptoms and improve recovery after the injury.
Fort Bragg, North CarolinaAges 18–50 - NCT05052541RecruitingPhase 3
Oral cannabis for long-term spine pain
This trial studies whether taking cannabis by mouth can safely reduce chronic spine pain and improve daily comfort. You may be eligible if you have long-lasting spine pain and can follow study rules about stopping or limiting other cannabis and certain other treatments.
Aurora, ColoradoAges 21–84 - NCT05052853RecruitingPhase 2
Early treatment trial for early schizophrenia warning signs
This Phase 2 study tests an NMDA-enhancer medicine to see if it can help people who are in the early “prodromal” stage—when symptoms are starting but full schizophrenia is not diagnosed yet. It aims to reduce or prevent worsening symptoms over the study period.
TaichungAges 13–45
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,962 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.