Clinical trials
Placebo Effect clinical trials
Below are recruiting placebo effect clinical trials, each written for real people, not researchers. We’re tracking 725 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06968559RecruitingPhase 3
Early steroid treatment for severe burns
This study tests whether giving a steroid called dexamethasone early after a severe burn can reduce serious complications and the risk of death. It is for adults on a breathing machine with large burns.
Chambray-lès-ToursAges 18–80 - NCT06707194RecruitingPhase 4
Penicillin plus etanercept for spondyloarthritis
This trial tests whether adding a common antibiotic (benzathine penicillin) to a standard biologic drug (etanercept) can better treat spondyloarthritis. It may help if you have active disease and are free of certain infections.
Hefei, AnhuiAges 18–59 - NCT06507657RecruitingEarly Phase 1
Empagliflozin for heart health in older adults
This study tests whether a medication called empagliflozin (a diabetes drug) can improve heart function in older adults with high blood pressure and obesity who are at risk for heart failure but do not have it yet. You would take the pill daily and have heart ultrasounds to check your heart's health.
Minneapolis, MinnesotaAges 60 years+ - NCT06183307Recruiting
Nattokinase for heart health in people with high cholesterol
This trial tests whether nattokinase, a natural enzyme, can reduce inflammation and improve heart health in people with high cholesterol or high triglycerides. If you have elevated LDL or triglycerides, you may be eligible even if you are already taking cholesterol medication.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT06122207Recruiting
Probiotic for women with fertility issues and IVF
This study tests whether a probiotic (a pill with beneficial bacteria) can help improve the health of the female genital tract for people with fertility problems who are undergoing IVF. It aims to see if this can improve chances of pregnancy.
LisbonAges 18–45 - NCT06082037RecruitingPhase 3
Testing belumosudil for chronic lung allograft dysfunction after transplant
This trial tests an oral medication called belumosudil for people with chronic lung allograft dysfunction (CLAD) after a double lung transplant. It may help slow the decline in lung function.
Birmingham, AlabamaAges 18 years+ - NCT05786066RecruitingPhase 2
Test whether blocking AMPA changes ketamine’s suicide relief
This study looks at whether an “AMPA receptor blocker” changes how ketamine affects suicidal thoughts in people with depression that hasn’t improved with usual treatments. If you qualify, you may receive ketamine and the study medicine, while continuing your regular mental health care.
West Haven, ConnecticutAges 21–65 - NCT05681299RecruitingPhase 4
Testing growth hormone and liraglutide effects on hunger hormones
This study tests how growth hormone (GH) and liraglutide affect a hunger-related hormone system called AgRP. It compares effects in healthy people (lean or overweight) and in people with isolated GH deficiency, aiming to understand how these treatments change appetite and metabolism.
New York, New YorkAges 18–45 - NCT05701969RecruitingEarly Phase 1
Melatonin for sleep during night shifts in residents
This early study tests whether melatonin can improve sleep patterns for doctors-in-training during overnight “night float” shifts. It may help you feel more rested and adjust to night work.
Charlottesville, VirginiaAges 18 years+ - NCT05664516RecruitingPhase 2
Oxytocin treatment study for binge eating disorder adults
This Phase 2 trial tests whether oxytocin (a hormone-like medication) can reduce binge-eating symptoms in adults with binge-eating disorder (including related conditions like bulimia or certain feeding/eating disorders). You may be eligible if your symptoms match the trial’s specific diagnosis rules and you can safely take the study medication.
Boston, MassachusettsAges 18–70 - NCT05526196Recruiting
Study how cannabis and tobacco affect reaction and feelings
This study tests how cannabis and tobacco—used together or separately—affect your thinking speed, how you feel, and body responses. You may help researchers understand these effects under controlled conditions, which could be useful for safer use and treatment decisions.
Toronto, OntarioAges 19–45 - NCT05352919Enrolling by invitationPhase 3
Long-term study of litifilimab for lupus symptom control
This study follows people with systemic lupus erythematosus (SLE) who already took part in an earlier, 1-year placebo-controlled trial. It looks at the long-term safety of litifilimab and whether it helps improve lupus symptoms over time.
Phoenix, ArizonaAges 18 years+ - NCT05282277RecruitingPhase 4
Estradiol to improve brain and reward changes in midlife women
This study tests whether a hormone called estradiol (given as a patch and pill) changes how the brain and body respond to reward in some midlife women with low pleasure and/or psychosis symptoms during menopause transition. It may help researchers understand whether estrogen treatment can improve mood-related “reward” function in this group.
Chapel Hill, North CarolinaAges 45–55 - NCT04789148RecruitingPhase 1
Nasal oxytocin trial for people with hormone deficiency
This early-phase study tests whether a spray of oxytocin in the nose can be given safely and may affect symptoms in people with arginine-vasopressin deficiency. You might qualify if your hormone levels are stable and you can safely take the nasal study medicine during the study period.
Boston, MassachusettsAges 18 years+ - NCT04601038RecruitingPhase 2
Testing a stress-blocking drug for early Alzheimer's risk
This study tests a new medication, CORT108297, that may help protect the brain from the harmful effects of stress in people at risk for Alzheimer's disease. It is looking for adults age 55 and older who either have mild memory problems or are healthy but have a family history, APOE4 gene, or memory concerns.
Baltimore, MarylandAges 55 years+ - NCT07624305RecruitingPhase 3
Balcinrenone and Dapagliflozin for Moderate-to-Severe Kidney Disease
This study tests a combination of two medications (balcinrenone and dapagliflozin) to help protect your kidneys if you have moderate-to-severe chronic kidney disease. The trial evaluates whether this combination slows kidney damage and improves kidney health.
Huntsville, AlabamaAges 18–99 - NCT07302880Recruiting
How biotin affects blood test results
This study looks at how taking biotin (a common vitamin) might interfere with routine blood tests. It is for healthy individuals who want to understand if their vitamin supplement could change their lab results.
CopenhagenAges 20–70 - NCT06983054RecruitingPhase 4
Salt, kidneys, and ertugliflozin in type 2 diabetes
This study tests if changing how much salt you eat affects how the drug ertugliflozin works in people with type 2 diabetes. You would take either the drug or a placebo (a dummy pill) for a short time while following a low- or high-salt diet, to see how your kidneys and blood vessels respond.
Denver, ColoradoAges 18–85 - NCT04650880Recruiting
Vitamin D study for irregular periods from PCOS
This trial studies whether taking vitamin D can improve ovulation (the release of an egg) in people with PCOS who have long, irregular menstrual cycles. It may help some participants have more regular ovulation and cycle timing, but you would be monitored with vaginal ultrasound and blood tests.
Hong KongAges 18–40 - NCT07757529Recruiting
Sage extract for thinking and memory in middle-aged adults
This study tests whether a daily sage extract supplement can improve thinking, focus, and memory in healthy middle-aged adults. If it works, it could offer a natural way to support brain health.
College Station, TexasAges 40–60 - NCT06620679Recruiting
Brain inflammation and stress in healthy men
This study explores how inflammation in the body affects the brain's response to stress. Healthy men will have brain scans and stress tests to understand this link better.
Leuven, Flemish BrabantAges 18–45 - NCT06639789Recruiting
Vitamin B12 effect on cycling performance
This trial tests a new Vitamin B12 supplement to see if it improves physical and mental performance in cyclists. It might help if you are a healthy male cyclist training regularly.
La Ñora, MurciaAges 18–45 - NCT07691749Recruiting
Psychobiotics plus antidepressants for Major Depression
This study tests whether adding psychobiotics (special probiotics for mental health) to your current antidepressant helps treat major depression better than the antidepressant alone. It may be an option if you have moderate to severe depression and are on a stable antidepressant dose.
Lahore, Punjab ProvinceAges 18–60 - NCT06061926RecruitingPhase 2
Celery seed for metabolic syndrome
This trial tests whether celery seed can improve the key features of metabolic syndrome, such as blood sugar, cholesterol, and blood pressure. It may help people whose condition is not yet being treated with medication.
Guadalajara, JaliscoAges 30–60
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Common questions
- Are there clinical trials for placebo effect?
- Yes. Clin2 currently lists 725 recruiting placebo effect studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo effect trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo effect trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.