Clinical trials
Placebo Effect clinical trials
Below are recruiting placebo effect clinical trials, each written for real people, not researchers. We’re tracking 754 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05919745RecruitingPhase 4
Ibuprofen before mouth surgery to reduce pain sensing
This trial studies whether taking ibuprofen before tooth extraction and bone graft surgery can lower how much pain you feel afterward. It may help by changing the body’s pain response during healing.
Milwaukee, WisconsinAges 18 years+ - NCT06048380RecruitingPhase 3
Ripasudil drops for FED patients having cataract surgery
This trial tests if ripasudil eye drops can help people with Fuchs' endothelial dystrophy (FED) during and after cataract surgery. It aims to see if the drops protect the eye's inner layer and improve recovery.
Singapore, SingaporeAges 50–100 - NCT06069531Recruiting
Probiotic or White Pomegranate for Vaginal Health
This study tests whether taking a probiotic (Lactobacillus Johnsonii) or a white pomegranate extract can improve vaginal health in women with an imbalance in vaginal bacteria. It aims to find a natural way to support a healthy vaginal environment.
TaichungAges 20–45 - NCT06183307Recruiting
Nattokinase for heart health in people with high cholesterol
This trial tests whether nattokinase, a natural enzyme, can reduce inflammation and improve heart health in people with high cholesterol or high triglycerides. If you have elevated LDL or triglycerides, you may be eligible even if you are already taking cholesterol medication.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT06507657RecruitingEarly Phase 1
Empagliflozin for heart health in older adults
This study tests whether a medication called empagliflozin (a diabetes drug) can improve heart function in older adults with high blood pressure and obesity who are at risk for heart failure but do not have it yet. You would take the pill daily and have heart ultrasounds to check your heart's health.
Minneapolis, MinnesotaAges 60 years+ - NCT06707194RecruitingPhase 4
Penicillin plus etanercept for spondyloarthritis
This trial tests whether adding a common antibiotic (benzathine penicillin) to a standard biologic drug (etanercept) can better treat spondyloarthritis. It may help if you have active disease and are free of certain infections.
Hefei, AnhuiAges 18–59 - NCT07403604RecruitingPhase 1
Lowering Insulin to Reduce Fat Buildup in the Liver
This study tests if lowering insulin levels can reduce fat buildup in the liver for people with a fatty liver condition called MASLD. It's looking for adults who are overweight and have early signs of insulin resistance but not diabetes.
New York, New YorkAges 18–65 - NCT06903546RecruitingPhase 4
Propolis for cholesterol in type 2 diabetes
This trial tests if taking propolis (a bee product) can help lower cholesterol in people with type 2 diabetes. It is for those whose diabetes is well-controlled and who are already on cholesterol medication.
JakartaAges 35–59 - NCT06965426Recruiting
Eye vitamins and skin test: a crossover study
This study tests whether a supplement containing lutein, zeaxanthin, and meso-zeaxanthin can increase the amount of these nutrients in your skin. You will take the supplement and a placebo at different times to see if there is a difference.
Kansas City, MissouriAges 18 years+ - NCT06968559RecruitingPhase 3
Early steroid treatment for severe burns
This study tests whether giving a steroid called dexamethasone early after a severe burn can reduce serious complications and the risk of death. It is for adults on a breathing machine with large burns.
Chambray-lès-ToursAges 18–80 - NCT07039747RecruitingPhase 2
Can a dietary supplement help people with irritable bowel syndrome?
This trial is testing if a dietary supplement can reduce symptoms of irritable bowel syndrome (IBS). You might qualify if you have been diagnosed with IBS, have moderate to severe symptoms, and are between 18 and 75 years old.
Rouen, FranceAges 18–75 - NCT07088302Recruiting
Lactase enzyme for feeding intolerance in preterm babies
This trial tests if giving lactase enzyme supplements helps preterm babies (born at or before 32 weeks) tolerate their feedings better. If your baby was born early and started feeding within the first few days of life, this study may be a good fit.
AlexandriaAges 3 days–1 month - NCT07546409Recruiting
Do ketones help thinking in older adults with prediabetes?
This study looks at whether a supplement called ketones can improve thinking and memory in older adults who have prediabetes but not diabetes or memory problems. You will take the supplement, have brain scans, and complete thinking tests.
Birmingham, AlabamaAges 60–75 - NCT07286188RecruitingPhase 4
Misoprostol for fluid use in fibroid surgery
This study tests if giving misoprostol (a medication given as a rectal suppository) during a hysteroscopic myomectomy helps reduce the amount of fluid used during the surgery. It may lead to a safer procedure for removing small uterine fibroids.
Chicago, IllinoisAges 18–50 - NCT07341750Recruiting
Probiotic study for immune health in school-aged children
This trial tests whether a probiotic called Bacillus Coagulans SNZ 1969 can support the immune health of healthy children aged 6 to 12. Your child would take the probiotic or a placebo daily for a period while keeping their usual routine.
London, OntarioAges 6–12 - NCT07466108Recruiting
IV paracetamol during emergency abdominal surgery
This trial tests whether giving paracetamol (Tylenol) through a vein during emergency belly surgery helps keep your blood pressure and heart rate stable. It may be an option for adults who are not critically unstable or have certain serious heart conditions.
Cairo, Cairo GovernorateAges 21–65 - NCT07339280Enrolling by invitation
Probiotics for COPD: symptoms, lungs, and inflammation
This study tests whether taking a probiotic can improve symptoms, lung function, and inflammation in people with COPD. It is for adults with stable COPD who have not had a flare-up or treatment change in the last two months.
KarlovacAges 18 years+ - NCT07302880Recruiting
How biotin affects blood test results
This study looks at how taking biotin (a common vitamin) might interfere with routine blood tests. It is for healthy individuals who want to understand if their vitamin supplement could change their lab results.
CopenhagenAges 20–70 - NCT06983054RecruitingPhase 4
Salt, kidneys, and ertugliflozin in type 2 diabetes
This study tests if changing how much salt you eat affects how the drug ertugliflozin works in people with type 2 diabetes. You would take either the drug or a placebo (a dummy pill) for a short time while following a low- or high-salt diet, to see how your kidneys and blood vessels respond.
Denver, ColoradoAges 18–85 - NCT05762107RecruitingTeam says not enrollingPhase 2
Drug ZT-01 to reduce low blood sugar at night
This Phase 2 study tests ZT-01 to help prevent night-time low blood sugar (hypoglycemia) in people with type 1 diabetes. It may help if you’ve had low blood sugar during sleep or are at high risk based on recent glucose monitoring.
Birmingham, AlabamaAges 18–75 - NCT06066606Recruiting
Exercise performance and vilanterol study
This trial tests how a common asthma medication affects exercise performance in healthy, fit young adults. You may be able to join if you are very active and have high fitness levels.
Copenhagen, DKAges 18–39 - NCT07224269RecruitingEarly Phase 1
Terazosin for energy levels in ALS
This study tests whether a blood pressure medicine called terazosin can boost energy production in cells of people with ALS, potentially slowing the disease. It involves taking the medication daily for a period and monitoring safety and effects.
Iowa City, IowaAges 18–80 - NCT06826755Recruiting
Melatonin for heart health in midlife women
This study tests whether melatonin can help improve heart health in midlife women with high blood pressure. It involves taking a melatonin pill or placebo for several weeks and checking blood pressure and other health markers.
Rochester, MinnesotaAges 40–55 - NCT07757529Recruiting
Sage extract for thinking and memory in middle-aged adults
This study tests whether a daily sage extract supplement can improve thinking, focus, and memory in healthy middle-aged adults. If it works, it could offer a natural way to support brain health.
College Station, TexasAges 40–60
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Common questions
- Are there clinical trials for placebo effect?
- Yes. Clin2 currently lists 754 recruiting placebo effect studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo effect trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo effect trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.