Clinical trials
Placebo clinical trials
Below are recruiting placebo clinical trials, each written for real people, not researchers. We’re tracking 5,245 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05066308RecruitingPhase 2
Cannabidiol to reduce inflammation in chronic low back pain
This Phase 2 study tests cannabidiol (CBD) to calm inflammation in the brain that may be linked to chronic low back pain. If you qualify, you’ll take study CBD and undergo brain imaging to see whether inflammation changes.
Boston, MassachusettsAges 18–75 - NCT05066633RecruitingPhase 3
Metoprolol added to standard care to prevent heart muscle damage
This trial tests whether adding metoprolol (a beta-blocker) to usual care can prevent or slow cardiomyopathy (heart muscle weakness) in people with Duchenne muscular dystrophy (DMD). It also checks for safety, especially effects on heart rate and rhythm.
Gdansk, Pomeranian VoivodeshipAges 8–17 - NCT05075161RecruitingPhase 3
Pirfenidone to help prevent lung scarring in ARDS
This Phase 3 trial tests whether pirfenidone can prevent or reduce lung scarring (fibrosis) in adults with ARDS who are within about a week of their illness starting. It may help by lowering harmful inflammation and the body’s scarring response.
Milan, MIAges 18 years+ - NCT05079763Recruiting
Hydrogel treatment to reduce skin damage after breast radiation
This trial tests a bacterial cellulose–based gel with a soothing ingredient (monolaurin) to help prevent or lessen painful skin reactions in the area receiving breast radiation. It focuses on people who have already finished surgery and chemotherapy and are about to start a planned radiation treatment schedule.
ManilaAges 18–80 - NCT05080946RecruitingEarly Phase 1
Aspirin with chemotherapy to improve ovarian tumor immune features
This early-phase study tests whether adding aspirin to standard neoadjuvant chemotherapy can change immune (anti-tumor) features inside ovarian, fallopian tube, or peritoneal tumors. It may help doctors better understand which patients respond and how aspirin could make treatment work better.
Tampa, FloridaAges 18 years+ - NCT05084196RecruitingPhase 3
Melatonin to help prevent kidney damage from vancomycin
This Phase 3 study tests whether melatonin can help protect the kidneys in people who are starting or continuing vancomycin, an antibiotic that can sometimes affect kidney function. If you qualify, you would take melatonin as an added prevention step while you’re on vancomycin.
New Brunswick, New JerseyAges 18–75 - NCT05090891RecruitingPhase 2
Study medicine INCB000928 for fibrodysplasia ossificans progressiva
This Phase 2 study tests whether INCB000928 can safely help people with fibrodysplasia ossificans progressiva (FOP). It mainly looks at whether the treatment is effective and well-tolerated, and it involves scheduled whole-body scans using low-dose X-rays.
Rochester, MinnesotaAges 2–99 - NCT05092191RecruitingPhase 2
Cannabis pill study for MS-related muscle stiffness
This Phase 2 trial tests whether cannabis can reduce muscle stiffness (spasticity) in people with multiple sclerosis. You may be able to participate if your stiffness is not improving with your current treatments.
Montreal, QuebecAges 21 years+ - NCT05092984RecruitingPhase 3
Spironolactone for rheumatoid arthritis with active symptoms
This trial tests whether spironolactone can reduce symptoms and inflammation in people with rheumatoid arthritis that is still active despite standard arthritis medicines. You may be able to join if your rheumatoid arthritis remains active and your current treatment plan has been stable for at least several months.
Strasbourg, AlsaceAges 18 years+ - NCT05095532RecruitingPhase 1
TP-IAT transplant with your own cells for type 1 diabetes
This early-stage study tests whether adding your own special cells (mesenchymal stromal cells) at the same time as a TP-IAT transplant can improve diabetes outcomes. It may help people who are already planning TP-IAT, but it is only for certain age, diabetes, and health criteria.
Charleston, South CarolinaAges 18 years+ - NCT05095857RecruitingPhase 4
Ketamine to improve care in severe acute brain injury
This Phase 4 trial tests whether giving ketamine during anesthesia is safe and helpful for adults with severe sudden brain injuries after surgery. It may improve how patients are sedated and cared for while they are on a breathing machine.
CopenhagenAges 18 years+ - NCT05097261RecruitingPhase 4
Ketamine for adults with severe brain injury in the ICU
This trial studies whether ketamine can improve outcomes for adults with severe traumatic brain injury when they are in the ICU and need sedation. It focuses on patients who have pressure monitoring inside the brain soon after admission.
BonheidenAges 18 years+ - NCT05100381Recruiting
Dry needling for long-lasting lower back muscle pain
This study tests whether dry needling (thin needles placed into specific muscles) can reduce moderate, long-lasting lower back pain. It focuses on people who have pain from trigger points in a specific back muscle, rather than pain caused by other medical problems.
Tehran, Tehran ProvinceAges 18–45 - NCT05104983RecruitingPhase 2
Sirolimus to prevent first seizures in babies with TSC
This Phase 2 study tests whether sirolimus (a targeted medicine) can stop or slow the start of seizures in very young babies diagnosed with tuberous sclerosis complex (TSC). If seizures are prevented early, it may also help protect early brain development.
Birmingham, AlabamaAges 1 day–6 months - NCT05106608Recruiting
Mobile plus light therapy for dry mouth after head and neck cancer
This study tests whether “photobiomodulation” light therapy, guided by a phone app, can improve chronic dry mouth (xerostomia) in people who finished radiation for head and neck cancer. It may help reduce bothersome mouth dryness and support better day-to-day comfort after treatment.
Granada, GranadaAges 18 years+ - NCT05112328Recruiting
Pancreatic enzyme added to feeding for ICU adults
This study tests whether adding pancreatic digestive enzymes to tube feeding can improve digestion and outcomes in critically ill adults who have higher risk of not producing enough digestive enzymes. If you qualify, you may receive the enzyme supplement or a comparison treatment while you’re in the ICU.
Seoul, Jongno-guAges 18 years+ - NCT05114096RecruitingPhase 4
One-time steroid shot to help babies stay healthier early
This trial studies whether giving a single steroid medicine shot during pregnancy can improve outcomes when preterm birth is at risk. The goal is to help the baby’s lungs and overall health before early delivery.
Calgary, AlbertaAges 18–55 - NCT05116475RecruitingPhase 3
New prostate cancer trial adding darolutamide to standard treatment
This Phase 3 trial tests whether adding darolutamide to standard hormone therapy and radiation works better than standard treatment alone for newly diagnosed prostate cancer that has spread to pelvic lymph nodes. If you qualify, you may receive darolutamide or a placebo alongside long-term hormone therapy and radiation.
Chambray-lès-ToursAges 18–120 - NCT05123755RecruitingPhase 2
Testing a new medicine in hospitalized pneumonia patients needing oxygen
This Phase 2 trial tests an investigational medicine (given in increasing doses) for hospitalized people with pneumonia who need supplemental oxygen. It aims to see if the medicine is safe and potentially helps the pneumonia process in the early hospital period.
Newport Beach, CaliforniaAges 18 years+ - NCT05132439RecruitingPhase 3
Metformin to improve walking in leg artery blockage
This Phase 3 study tests whether metformin can help people with intermittent claudication (leg pain when walking) walk farther. It compares how well metformin works on walking ability alongside standard (already recommended) heart and blood-vessel medicines.
Pittsburgh, PennsylvaniaAges 35–89 - NCT05136755RecruitingPhase 2
NMDA treatment for depression that did not improve
This trial studies an NMDA-based treatment for people with major depressive disorder who did not respond to at least one antidepressant. It may help by changing brain signaling linked to depression symptoms.
TaichungAges 18–65 - NCT05140148RecruitingPhase 2
Amantadine to help recovery after stroke
This Phase 2 study tests whether the medicine amantadine can improve recovery after a recent stroke. It may help some people regain function during early rehabilitation.
Philadelphia, PennsylvaniaAges 18–85 - NCT05142267Recruiting
Study stress and opioid-risk factors in chronic low back pain
This study looks at how stress and the body’s natural opioid/cannabinoid systems may relate to risk of opioid misuse. It tests people with long-lasting low back pain to see what biological or psychological factors might increase or lower that risk.
Nashville, TennesseeAges 18 years+ - NCT05142735Recruiting
NAC for early psychosis risk symptoms
This trial studies whether NAC (a nutrient-like supplement) can reduce symptoms in people who are at high risk for developing psychosis. It may help by testing a safer, non-standard treatment approach for early warning signs.
Toronto, OntarioAges 16–35
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Common questions
- Are there clinical trials for placebo?
- Yes. Clin2 currently lists 5,245 recruiting placebo studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.