Clinical trials
Placebo clinical trials
Below are recruiting placebo clinical trials, each written for real people, not researchers. We’re tracking 5,154 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06004115RecruitingPhase 4
Brain scanning study for depression and anxiety
This study uses brain scans (fMRI) to understand how people with both depression and anxiety respond to threat. If you have either or both conditions, participating could help researchers find better treatments.
Tulsa, OklahomaAges 18–65 - NCT05367245RecruitingPhase 2
Butyrate supplement for Gulf War illness symptoms
This Phase 2 study tests whether a calcium–magnesium butyrate supplement can reduce symptoms of Gulf War Illness (GWI), especially by targeting gut and immune-related pathways. You may be eligible if you’re a Gulf War–era veteran with moderate-to-severe physical symptoms and no conditions or medicines that could explain them instead.
Long Beach, CaliforniaAges 40–70 - NCT05588934Recruiting
Testing the best daily caffeine dose for sleep and alertness
This study compares an adjusted caffeine plan versus a typical caffeine dose to see how it affects your sleep timing and daytime alertness. It may help find a caffeine amount that supports wakefulness without disrupting sleep.
Tucson, ArizonaAges 18–39 - NCT05616819Recruiting
Morning light program to improve mood in some service members
This study tests whether getting morning light exposure can improve mood for service members who currently have mild or more depression symptoms. You’d follow a plan for morning light over about 6 weeks, and the researchers check changes in mood.
Tucson, ArizonaAges 18–60 - NCT05837897RecruitingPhase 3
Vedolizumab for adults with moderate-to-severe Crohn’s
This Phase 3 study tests whether vedolizumab can better control moderate-to-severe Crohn’s disease in adults whose symptoms haven’t improved enough with other treatments. You’d need to meet specific symptom scores, recent colonoscopy findings, and safety checks (including infections and vaccination status).
Hefei, AnhuiAges 18–80 - NCT05885542RecruitingPhase 1/Phase 2
Testing CBD pills for cannabis use and stress in young adults
This early-phase study tests whether a CBD pill (compared with a placebo sugar pill) can affect cannabis use and stress in people ages 18–25 who use cannabis very frequently. It may help your stress levels and cannabis-related symptoms while researchers carefully monitor safety and abstinence periods during visits.
Charleston, South CarolinaAges 18–25 - NCT03312556Recruiting
CPAP for high blood pressure when lying down
This trial looks at whether using CPAP (a breathing device) can help control high blood pressure that happens when you lie down, in people with autonomic failure. It’s designed for safety and effectiveness and may improve symptoms and blood pressure control.
Nashville, TennesseeAges 18–85 - NCT06075745RecruitingPhase 2
CMV Vaccine Study for Liver Transplant Candidates
This trial tests a vaccine to prevent cytomegalovirus (CMV) infection in people awaiting a first liver transplant. You may be eligible if you have never been infected with CMV and are scheduled to receive a liver transplant within the next 1 to 12 months.
Birmingham, AlabamaAges 18 years+ - NCT06072482RecruitingPhase 4
Avacopan for ANCA-associated vasculitis
This trial tests a medication called avacopan for people with ANCA-associated vasculitis, a condition where the immune system attacks blood vessels. Avacopan is taken with standard treatments to help control the disease and may reduce the need for steroids.
Anchorage, AlaskaAges 18–100 - NCT06064877RecruitingPhase 3
Study of ficlatuzumab plus cetuximab for advanced head and neck cancer
This trial tests a combination of two drugs, ficlatuzumab and cetuximab, for people with recurrent or metastatic head and neck cancer that is HPV-negative and has not responded to prior immunotherapy and chemotherapy. It aims to see if this combination can help shrink tumors or slow the disease.
Gilbert, ArizonaAges 18 years+ - NCT06079671RecruitingPhase 3
Volrustomig for high-risk locally advanced cervical cancer
This trial tests a new medicine called volrustomig for women with locally advanced cervical cancer that has not spread. It is given along with standard chemoradiation and aims to improve outcomes.
Birmingham, AlabamaAges 15 years+ - NCT05015439RecruitingPhase 1
CBD study for adults with autism and challenging symptoms
This Phase 1 study tests cannabidiol (CBD) in adults on the autism spectrum who also have mood, sleep, or behavior problems. The goal is to learn whether CBD can be given safely and may help symptoms that affect daily life.
Baltimore, MarylandAges 18 years+ - NCT06075914Recruiting
Ketones and sleep: can nutrition help?
This study tests if a special nutritional supplement (ketones) can help your body stay resilient when you don't get enough sleep. If you join, you'll follow a specific diet and have your sleep and health monitored for about 9 weeks.
Columbus, OhioAges 18–40 - NCT06066710RecruitingEarly Phase 1
Propranolol for Primary Progressive Aphasia
This trial tests whether the drug propranolol, often used for high blood pressure, can help people with primary progressive aphasia (a condition that slowly affects language skills). You would take the drug and have MRI brain scans to see if it slows language decline.
Columbia, MissouriAges 50 years+ - NCT06058702RecruitingPhase 1
Genetics of cannabis use disorder and response
This study looks at how genes affect cannabis use disorder and how people respond to cannabis. It may help explain why some people develop problems with cannabis while others do not.
West Haven, ConnecticutAges 21–60 - NCT06058442RecruitingPhase 3
Digestive enzymes after stomach surgery trial
This trial tests whether taking a digestive enzyme supplement called NORTASE® after stomach surgery helps improve digestion and nutrition. It may help people who have had most or all of their stomach removed due to cancer or other conditions.
BornaAges 18 years+ - NCT06059391RecruitingPhase 2
Vaccine for stem cell donors to prevent CMV
This trial tests whether giving a CMV vaccine to stem cell donors can help protect recipients from CMV infection after transplant. It is for adults with specific blood cancers who are CMV-positive and have a matched related donor.
Duarte, CaliforniaAges 18–75 - NCT06066996RecruitingEarly Phase 1
Study of withdrawal symptoms when people vape less
This study looks at what happens when people who vape nicotine daily try to cut back. Researchers want to understand withdrawal symptoms and find better ways to help people reduce or quit vaping.
Baltimore, MarylandAges 21–55 - NCT06078683Recruiting
Ketone drink for exercise and heart health in type 2 diabetes
This study tests whether a special ketone drink can improve exercise ability and heart function in people with type 2 diabetes. Participants will have two treadmill exercise tests and heart MRI scans to see how the drink affects their performance and cardiac efficiency.
Columbus, OhioAges 18–80 - NCT06063486RecruitingPhase 2
Curcumin for inflammation and symptoms in blood disorders
This trial tests whether curcumin, a natural compound found in turmeric, can reduce inflammation and improve symptoms like fatigue in people with certain blood disorders that cause low blood counts or overproduction of blood cells. It is for patients with clonal cytopenia of uncertain significance, low-risk myelodysplastic syndrome, or myeloproliferative neoplasms (polycythemia vera, essential thrombocytosis, or myelofibrosis) who have bothersome symptoms.
Los Angeles, CaliforniaAges 18 years+ - NCT06059664RecruitingPhase 2
Finerenone for kidney transplant recipients: the EFFEKTOR study
This study tests whether a medicine called finerenone can help protect kidney transplants from further damage. People who have had a kidney transplant and have protein in their urine may benefit from this treatment.
Chapel Hill, North CarolinaAges 18 years+ - NCT06058520RecruitingEarly Phase 1
Capsule microbiome transplant for hidradenitis suppurativa
This trial tests whether taking capsules containing healthy gut bacteria (fecal microbiota transplant) can help treat hidradenitis suppurativa. You may qualify if you have HS and haven't taken antibiotics in the last 30 days.
Minneapolis, MinnesotaAges 18 years+ - NCT06075771RecruitingPhase 4
Testing a Parkinson's drug for depression-related loss of interest
This trial tests whether a medication used for Parkinson's disease (carbidopa-levodopa) can help people with major depression who have lost interest or pleasure in things. It is for adults who have not been helped enough by other treatments and have signs of inflammation.
Atlanta, GeorgiaAges 25–55 - NCT06070350RecruitingPhase 3
Massive transfusion for life-threatening bleeding in children
This study tests whether adding the drug tranexamic acid (TXA) to a massive blood transfusion helps control life-threatening bleeding in children who are severely injured. It compares two groups: one gets TXA and the other gets a placebo (a dummy drug with no active ingredient).
Tucson, ArizonaAges Up to 17 years
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Common questions
- Are there clinical trials for placebo?
- Yes. Clin2 currently lists 5,154 recruiting placebo studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.