Clinical trials
Polyneuropathies clinical trials
Below are recruiting polyneuropathies clinical trials, each written for real people, not researchers. We’re tracking 68 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07461896Recruiting
Nerve function study in Charcot-Marie-Tooth and related neuropathies
This study looks at how nerves work and their structure in people with Charcot-Marie-Tooth disease, CIDP, or anti-MAG neuropathy. It may help doctors better understand these conditions.
MilanAges 18 years+ - NCT06044662Recruiting
Predicting nerve damage with blood markers
This study looks at certain markers in the blood that may help predict how polyneuropathy (nerve damage) will progress. It involves physical tests, and results could help doctors better understand the condition.
CopenhagenAges 18 years+ - NCT07248631Recruiting
Exercises and mindful walking for diabetic nerve pain
This study tests whether combining foot and ankle exercises with mindful walking can reduce pain and improve mobility in people with diabetic nerve damage in their feet.
Multan, Punjab ProvinceAges 3.3 years–6.3 years - NCT07223203RecruitingPhase 3
Study of nucresiran for hereditary nerve condition (hATTR-PN)
This trial tests a new medicine called nucresiran for people with a rare genetic nerve condition (hATTR-PN). The goal is to see if it can slow down or improve nerve damage.
Aurora, ColoradoAges 18–85 - NCT07154524Recruiting
Immunoadsorption for CIDP treatment study
This trial tests whether a blood-filtering treatment called immunoadsorption can help people with CIDP. It is for adults who are already receiving or starting IVIg or MP therapy.
Ulm, Baden-WurttembergAges 18 years+ - NCT07032662RecruitingPhase 2
Study of imeroprubart for chronic inflammatory demyelinating polyneuropathy (CIDP)
This trial tests whether a new medicine called imeroprubart can help people with CIDP, a nerve condition causing weakness and numbness. It may provide an alternative to current treatments like steroids or immunoglobulin therapy.
Tucson, ArizonaAges 18 years+ - NCT07000214RecruitingPhase 2
Magnetic stimulation and balance training to prevent falls in diabetic nerve pain
This trial tests if adding a non-invasive magnetic stimulation treatment to balance exercises can reduce fall risk in people with type 2 diabetes who have nerve damage in their feet and legs.
Chon Buri, Changwat Chon BuriAges 50–75 - NCT06940336RecruitingPhase 4
Testing tafamidis for transthyretin amyloid polyneuropathy
This trial tests whether the drug tafamidis can help people with a specific type of nerve damage caused by abnormal protein buildup. It aims to slow or improve symptoms in adults with this condition.
JinanAges 18–80 - NCT06920004RecruitingPhase 3
Testing empasiprubart vs IVIg for chronic CIDP
This study tests an investigational drug called empasiprubart against standard IVIg in adults with CIDP. The goal is to see if it is safer and more effective for people who still have symptoms despite IVIg therapy.
Birmingham, AlabamaAges 18 years+ - NCT06904417Enrolling by invitationPhase 1
Feldenkrais method for balance in diabetic nerve pain
This trial tests whether a gentle movement technique called Feldenkrais can help people with diabetic nerve damage improve their balance and control. It may be an option if you have stable blood sugar and can walk on your own.
Cairo, Cairo GovernorateAges 45–60 - NCT06858579RecruitingPhase 3
Testing DNTH103 for chronic inflammatory demyelinating polyneuropathy (CIDP)
This trial tests a new drug called DNTH103 for adults with CIDP, a condition that affects nerves and causes weakness. It aims to see if the drug can help people who are currently on treatment, have tried treatment before, or are new to treatment.
Birmingham, AlabamaAges 18–75 - NCT05950867Recruiting
Testing how common wild-type TTR heart amyloidosis is
This study looks at how often a specific type of heart condition (wild-type TTR cardiac amyloidosis) occurs in people whose nerve symptoms have no clear cause. The results may help doctors spot this treatable problem earlier when neuropathy is unexplained.
Jette, Belgium Capital CityAges 60 years+ - NCT06778005Recruiting
Ultrasound of leg nerves in type 2 diabetes with nerve damage
This study uses ultrasound (an imaging test) to measure the nerves in the legs of people with type 2 diabetes who have nerve damage. It helps doctors learn more about how diabetes affects nerves.
Istanbul, ÜsküdarAges 18–65 - NCT06752356RecruitingPhase 3
A study of a new IVIG treatment for CIDP
This study tests a new intravenous immunoglobulin (IVIG) treatment called KIg10 (QIVIGY) for people with chronic inflammatory demyelinating polyneuropathy (CIDP). It aims to see if this treatment can help manage symptoms and maintain stability.
Stamford, ConnecticutAges 18 years+ - NCT06290141RecruitingPhase 3
Testing riliprubart vs. standard IVIg for CIDP
This trial tests whether a new medication called riliprubart works as well as the usual IVIg treatment for people with chronic inflammatory demyelinating polyneuropathy (CIDP). It may offer another option for managing your condition.
Homewood, AlabamaAges 18 years+ - NCT04699734Recruiting
Nerve block for nerve pain from diabetes
This trial studies whether a numbing “nerve block” can reduce long-lasting nerve pain caused by diabetic neuropathy. You may keep your usual pain medicines, and the study will mainly check whether you fit the safety and diagnosis criteria.
Aarhus N, JutlandAges 18 years+ - NCT03862365Recruiting
Study genetics in people with nerve pain
This study looks at genetic differences in people being checked for a common type of nerve problem called distal symmetric polyneuropathy (nerve damage that usually affects the hands and feet). By understanding genetics, researchers hope to learn more about why neuropathic (nerve) pain happens and how it may differ between people.
BergenAges 18–70 - NCT04589299RecruitingPhase 4
Subcutaneous immune globulin for newly diagnosed CIDP
This study tests whether giving immune globulin under the skin (SCIG) can help people with newly diagnosed CIDP. It may help improve muscle strength and nerve symptoms while avoiding the need for earlier IVIG/SCIG treatment.
AalborgAges 18 years+ - NCT07822932Recruiting
Ear nerve stimulation for HIV-related nerve pain
This study tests a gentle ear stimulation device that may ease tingling, burning, or numbness from HIV-related nerve damage in the hands and feet. It could offer a drug-free way to manage nerve pain.
Miami, FloridaAges 50 years+ - NCT06627348Recruiting
Cold gloves and socks for chemo nerve damage prevention
This trial tests if wearing cold gloves and socks during chemo can prevent nerve damage in hands and feet. It is for women with breast or genital cancer getting a taxane chemo drug for the first time.
Ulm, Baden-WurttembergAges 18 years+ - NCT07689214Recruiting
Normast for diabetic nerve pain in adults
This study tests an oral medication called Normast to see if it helps adults with diabetic polyneuropathy, a type of nerve damage from diabetes. The trial aims to find out if the drug can reduce symptoms and improve quality of life.
Rome, ItalyAges 18–80 - NCT07654855Recruiting
Long-term safety of eplontersen in ATTR patients
This study follows people who already took part in an earlier trial (D8450R00003) to see how safe eplontersen is over the long term. It also includes people who had a liver transplant or severe liver problems.
Los Angeles, CaliforniaAges 18 years+ - NCT06714838RecruitingPhase 3
Rituximab for remission in chronic inflammatory demyelinating polyneuropathy
This trial tests a drug called rituximab to see if it can help people with chronic inflammatory demyelinating polyneuropathy (CIDP) achieve remission. It may offer a new treatment option for those who are newly diagnosed or who are on maintenance therapy with wear-off symptoms or failed withdrawal attempts.
AmsterdamAges 18–80 - NCT06739135Recruiting
Driving with diabetic neuropathy study
This study looks at how diabetic neuropathy (nerve damage from diabetes) affects driving safety. You may join if you have type 2 diabetes with or without neuropathy and are an experienced driver in the UK.
ManchesterAges 25–69
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Common questions
- Are there clinical trials for polyneuropathies?
- Yes. Clin2 currently lists 68 recruiting polyneuropathies studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a polyneuropathies trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a polyneuropathies trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.