Clinical trials
Polyneuropathies clinical trials
Below are recruiting polyneuropathies clinical trials, each written for real people, not researchers. We’re tracking 71 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07392229RecruitingPhase 2
Zanubrutinib for Anti-MAG Neuropathy
This trial tests whether the oral drug zanubrutinib can help people with anti-MAG antibody polyneuropathy, a nerve condition often linked to certain blood cancers. It aims to improve nerve symptoms by targeting the immune cells responsible.
Milan, MilanAges 18 years+ - NCT06563895RecruitingPhase 3
Testing acoramidis to prevent ATTR amyloidosis in gene carriers
This trial tests a daily pill called acoramidis to see if it can prevent ATTR amyloidosis in people who carry a gene mutation but have no symptoms yet. It aims to stop the disease before it starts.
La Jolla, CaliforniaAges 18–75 - NCT05697861Enrolling by invitation
Follow-up study for people previously treated with NTLA-2001
This study checks how people are doing long-term after receiving NTLA-2001 in an Intellia clinical trial. If you previously took part and agree to be followed, this may help the researchers understand lasting safety and effects.
ParisAges 18 years+ - NCT05327114RecruitingPhase 2/Phase 3
Nipocalimab for adults with chronic inflammatory CIDP nerve disease
This trial tests nipocalimab (an antibody medicine) to improve symptoms and control activity in chronic inflammatory demyelinating polyneuropathy (CIDP), a nerve disease that causes weakness and numbness. It may help reduce disease activity and disability, while checking safety.
Centennial, ColoradoAges 18 years+ - NCT07091630RecruitingPhase 3
A study of empasiprubart for chronic inflammatory demyelinating polyneuropathy (CIDP)
This study tests a new medicine called Empasiprubart for adults with ongoing CIDP. It aims to see if fewer symptoms return and if it can replace current treatments.
Birmingham, AlabamaAges 18 years+ - NCT03717844Recruiting
Registry for adults with plasma cell disorders
This study is a registry that collects information about adults with plasma cell disorders (conditions involving abnormal antibody-producing cells). It may help researchers understand these diseases better and improve future care by tracking patients over time.
Chapel Hill, North CarolinaAges 18 years+ - NCT03810768Recruiting
Metabolomics study of ICU-acquired weakness after surgery
This study looks at blood and body chemistry (called metabolomics) to understand and possibly predict muscle weakness that can happen in the ICU after surgery. It may help researchers find better ways to prevent or monitor this problem.
Vienna, State of ViennaAges 18 years+ - NCT03862365Recruiting
Study genetics in people with nerve pain
This study looks at genetic differences in people being checked for a common type of nerve problem called distal symmetric polyneuropathy (nerve damage that usually affects the hands and feet). By understanding genetics, researchers hope to learn more about why neuropathic (nerve) pain happens and how it may differ between people.
BergenAges 18–70 - NCT04153422RecruitingPhase 2
IVIG for small fiber nerve pain with specific antibody tests
This trial studies whether IVIG (an immune therapy made from donated antibodies) can reduce pain from autoimmune small fiber neuropathy. You may be a candidate if your tests show certain autoantibodies (TS-HDS, FGFR3, or Plexin-D1) and your symptom scores are high enough.
Glenview, IllinoisAges 18 years+ - NCT04589299RecruitingPhase 4
Subcutaneous immune globulin for newly diagnosed CIDP
This study tests whether giving immune globulin under the skin (SCIG) can help people with newly diagnosed CIDP. It may help improve muscle strength and nerve symptoms while avoiding the need for earlier IVIG/SCIG treatment.
AalborgAges 18 years+ - NCT04672733Recruiting
Switch from IVIg to Hizentra for CIDP nerve inflammation
This study tests Hizentra® as an alternative to IV immunoglobulin (IVIg) for adults with CIDP, a condition where the immune system damages the nerves. You may be able to switch to Hizentra if your current IVIg treatment is keeping your CIDP stable and you can switch safely.
AmiensAges 18 years+ - NCT04699734Recruiting
Nerve block for nerve pain from diabetes
This trial studies whether a numbing “nerve block” can reduce long-lasting nerve pain caused by diabetic neuropathy. You may keep your usual pain medicines, and the study will mainly check whether you fit the safety and diagnosis criteria.
Aarhus N, JutlandAges 18 years+ - NCT04881682RecruitingPhase 2
Testing blood-cleansing vs immunoglobulin for CIDP
This Phase 2 study compares a blood-cleansing treatment (immunoadsorption) with standard immune-boosting treatment (intravenous immunoglobulins) for chronic inflammatory demyelinating polyneuropathy (CIDP). It may help people whose steroid treatment did not work well, or who cannot take steroids.
Ulm, Baden-WurttembergAges 18 years+ - NCT06859099Enrolling by invitationPhase 3
Long-term safety study of Riliprubart for CIDP
This study checks the long-term safety and how well riliprubart works for people with chronic inflammatory demyelinating polyneuropathy (CIDP). It is for those who have already taken riliprubart in a previous study.
Homewood, AlabamaAges 18 years+ - NCT05040373Recruiting
Pregnancy follow-up after patisiran exposure
This program tracks pregnancy outcomes for people who were exposed to patisiran (a medicine) in a special delivery form called LNP during pregnancy or shortly before. It helps doctors understand potential effects and safety for mothers and babies.
Iowa City, IowaAges Any age - NCT05283993Recruiting
Hospital study following people with plasma cell disorders
This is a hospital-based study that follows people with plasma cell disorders to better understand these conditions. It mainly gathers information from patients who are confirmed to have one of several related diseases.
BeijingAges Any age - NCT05584631RecruitingPhase 1
Switching IVIG to weekly SCIG for CIDP treatment
This Phase 1 study compares IVIG given through an IV versus SCIG given under the skin, for people with CIDP. It aims to find the right weekly SCIG dose based on your current IVIG dose, which could make treatment more convenient.
New Brunswick, New JerseyAges 18–65 - NCT06124586Recruiting
Early angioplasty for diabetic foot ulcers
This trial tests if an early procedure to open blocked leg arteries (angioplasty) helps heal foot ulcers in people with type 2 diabetes. It aims to improve blood flow and prevent amputation.
DüsseldorfAges 18 years+ - NCT06183645Recruiting
Predicting CIDP decline during IVIg treatment changes
This study looks at people with CIDP who are stable on IVIg treatment to see if we can predict when they might get worse if their treatment is adjusted. It aims to make treatment management easier and more personalized.
Liège, LiègeAges 18–99 - NCT06299748Recruiting
Efgartigimod safety study for pregnancy and breastfeeding
This study is for women who have taken efgartigimod (a medicine for certain autoimmune conditions) right before or during pregnancy, or while breastfeeding. Researchers will monitor moms, fetuses, and babies to check for side effects and ensure safety.
Morgantown, West VirginiaAges Any age - NCT06377033Recruiting
Using health records to advance genomic medicine for all
This study uses electronic health records to learn how to improve genomic medicine across a diverse health system. It may help make DNA-based healthcare more accessible and effective for people with certain conditions.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06452914Recruiting
Testing therapeutic socks for diabetic nerve pain
This study tests special socks with tiny electronic parts to see if they can reduce nerve pain, numbness, and tingling in people with diabetic neuropathy. If you have mild to moderate symptoms and are not taking new medications for it, you may be able to join.
Roswell, GeorgiaAges 18–79 - NCT06514846Recruiting
Early detection of nerve damage in diabetes
This study uses a simple screening tool to find nerve damage early in people recently diagnosed with type 2 diabetes. It may help you understand your risk and take steps to protect your nerves.
SohagAges 33–65 - NCT07689214Recruiting
Normast for diabetic nerve pain in adults
This study tests an oral medication called Normast to see if it helps adults with diabetic polyneuropathy, a type of nerve damage from diabetes. The trial aims to find out if the drug can reduce symptoms and improve quality of life.
Rome, ItalyAges 18–80
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Common questions
- Are there clinical trials for polyneuropathies?
- Yes. Clin2 currently lists 71 recruiting polyneuropathies studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a polyneuropathies trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a polyneuropathies trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.