Clinical trials
Post Operative Pain clinical trials
Below are recruiting post operative pain clinical trials, each written for real people, not researchers. We’re tracking 186 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06446830Recruiting
Vitamin B complex for pain relief after cesarean in ICU
This trial tests whether adding vitamin B complex to standard pain medicine can improve pain control after a cesarean section in critically ill women. It aims to find a safer, effective way to manage pain without relying too much on strong opioids.
Cairo, EgyptAges Any age - NCT06725862Recruiting
Pain relief methods for undescended testis surgery in children
This study compares two different numbing injections (caudal block vs retrolaminar block) given before surgery to see which one provides better pain control for children aged 1-7 undergoing undescended testis surgery.
IstanbulAges 1–7 - NCT06836882Recruiting
Testing cavity disinfectants for deep tooth decay pain
This study tests two cavity disinfectants to see which one better reduces pain and improves healing after removing deep decay from back teeth. It is for adults with deep cavities in their lower molars that are still alive (not needing a root canal).
HaryānaAges 18 years+ - NCT07375576Recruiting
Comparing partial nerve removal to root canal for severe tooth pain
This study compares two ways to treat severe tooth pain from advanced decay: a partial nerve removal (pulpotomy) versus a full root canal treatment. It aims to find which approach works better for saving the tooth.
Hatay, AntakyaAges 18–45 - NCT06864884RecruitingEarly Phase 1
Study of ARC-001 for wisdom teeth removal
This trial tests a new medicine called ARC-001 in people who are scheduled to have their wisdom teeth taken out. The goal is to see if it's safe and how it affects pain and healing.
Salt Lake City, UtahAges 18–55 - NCT06873893Recruiting
Nerve blocks for pain relief after mastectomy surgery
This study compares two types of ultrasound-guided nerve blocks to see which one provides better pain relief after a mastectomy. The blocks are injected near the chest wall to numb the area during and after surgery.
Cairo , AbbassyaAges 35–65 - NCT07281118Recruiting
Nerve freezing for pain after double lung transplant
This trial tests a procedure called intercostal cryoanalgesia, which freezes nerves in the chest to reduce pain after a double lung transplant. It may help you feel less pain and use fewer painkillers after surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT07222072RecruitingPhase 4
Methadone to reduce opioid use after spine surgery
This study tests whether giving methadone during and after major spine surgery can help reduce the need for other opioid pain medicines later. It is for adults having multilevel fusion in the lower or mid-back.
Cleveland, OhioAges 18–72 - NCT06088420Recruiting
Pain relief after cesarean section with nerve blocks
This study compares different nerve blocks for pain control after a planned cesarean delivery. The goal is to find which block provides the best pain relief with fewer side effects.
Asyut, ManfaloutAges 18–40 - NCT07210164Recruiting
Pre-surgery wellness program for gynecologic cancer surgery
This trial tests whether a pre-surgery wellness program (pre-habilitation) within an enhanced recovery protocol helps women recover better after surgery for endometrial, ovarian, or cervical cancer. It is designed for women who are having open abdominal surgery (laparotomy).
ThessalonikiAges 18–85 - NCT07202416Recruiting
Pain relief after c-section: nerve block vs spinal morphine
This study compares two ways to manage pain after a planned cesarean section: a nerve block near the spine (ESPB) versus morphine injected into the spinal fluid. The goal is to find which method helps mothers recover more comfortably.
Cesena, ForlìAges 18–45 - NCT06205875Recruiting
High vs. low dose pain block after minimally invasive heart valve surgery
This trial compares two doses of a numbing medicine injected into the chest wall to control pain after heart valve surgery. If you qualify, you will receive either a higher or lower dose of the pain block to see which provides better pain relief and recovery.
Hasselt, LimburgAges 18 years+ - NCT07095556Recruiting
Laser therapy to help gums heal after tooth extraction
This trial tests whether a special laser treatment can help your gums heal better after a tooth is removed and the socket is prepared for a future dental implant. If you're having a tooth pulled and bone preservation, this laser might speed up healing and reduce pain.
Charleston, South CarolinaAges 18 years+ - NCT07075055Recruiting
New bioceramic medication for infected front teeth
This trial tests a new bioceramic medication placed inside the root canal of infected front teeth to see if it improves healing. It is for adults with mature front teeth and an infection around the root tip, who are otherwise healthy.
MinyaAges 18–40 - NCT07034300RecruitingPhase 4
Comparing lidocaine with and without dexmedetomidine for arm surgery
This trial tests whether adding dexmedetomidine to lidocaine works better for numbing the arm during surgery. Patients get numbing medicine through a special IV in the arm while the surgery is happening.
Lahore, Punjab ProvinceAges 18–60 - NCT07023991Enrolling by invitationPhase 1
Dexmedetomidine with bupivacaine for children's lower abdominal surgery
This trial tests whether adding dexmedetomidine (a sedative) to bupivacaine (a numbing medicine) improves pain relief from a nerve block in young children having lower belly surgery. The goal is to see if the combination provides better or longer-lasting pain control.
Cairo, EgyptAges 1–7 - NCT06991231Recruiting
Cryoablation benefits in knee replacement surgery
This trial tests if a special cold treatment (cryoablation) can help reduce pain or improve recovery for people getting knee replacement surgery for arthritis. It might offer an extra option to feel better after the procedure.
New York, New YorkAges 18 years+ - NCT06982625Recruiting
Numbing injection after hip replacement for pain relief
This trial tests whether an injection of numbing medicine near the hip can help control pain after a hip replacement surgery. It may be an option for people who have significant pain after their operation.
ParisAges 18 years+ - NCT06979583Enrolling by invitation
Stent and sheath size and pain after kidney stone surgery
This study compares whether the size of the stent and the sheath used during kidney stone surgery affects how much pain you feel afterward. If you are having a stone removal procedure and will get a stent with a string, you may be able to join.
Rochester, MinnesotaAges 18 years+ - NCT06812832RecruitingPhase 4
Simethicone in bariatric surgery recovery
This trial tests if giving simethicone (a gas-relief medication) as part of a standard recovery plan helps patients feel better after weight-loss surgery. It may reduce bloating and discomfort after surgery.
Tacoma, WashingtonAges 18–89 - NCT05141591Recruiting
Anxiety before ENT surgery and opioid use after surgery
This trial looks at whether people’s anxiety before ear, nose, and throat (ENT) surgery affects how much pain medicine (opioids) they need after surgery. It may help doctors better plan pain control based on anxiety level and possibly gender-related patterns.
Vienna, State of ViennaAges 18 years+ - NCT06852248Recruiting
Green dye vs. ureter stent for endometriosis surgery
This trial compares two ways of protecting the ureter during deep endometriosis surgery: placing a small tube (stent) versus using a green dye (indocyanine green) to see the ureter. The goal is to see if the dye works just as well but causes less pain and fewer side effects afterward.
Stoke-on-Trent, StaffordshireAges 18–50 - NCT06777381Enrolling by invitation
Pain after root canal treatment in lower molars
This study compares how much pain people feel after a single root canal treatment on a lower back molar. It may help find a way to reduce discomfort after the procedure.
CairoAges 25–45 - NCT06721000Enrolling by invitation
Patient-controlled vs. standard epidural pain relief
This trial compares two types of epidural pain management during surgery. It tests whether letting you control your pain medication yourself works better than the standard method.
Karachi, SindhAges 19 years+
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Common questions
- Are there clinical trials for post operative pain?
- Yes. Clin2 currently lists 186 recruiting post operative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a post operative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a post operative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.