Clinical trials
Post Operative Pain clinical trials
Below are recruiting post operative pain clinical trials, each written for real people, not researchers. We’re tracking 197 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06949826RecruitingPhase 4
Buprenorphine for pain after ankle fracture surgery
This trial tests if buprenorphine, a non-opioid pain medicine, works well for people who have not used opioids before. After ankle fracture surgery, you would get buprenorphine instead of stronger opioids to see if it controls pain just as well with fewer side effects.
St Louis, MissouriAges 18 years+ - NCT06387914Recruiting
Deep brain stimulation for chronic stroke pain
This trial tests whether deep brain stimulation (using a device implanted in the brain) can help relieve severe, long-lasting pain caused by a stroke. It is for people who have tried other treatments without success.
Oxford, OxfordshireAges 21 years+ - NCT07715591Recruiting
Relaxing breathing during awake cataract surgery
This study tests a special breathing and pain education program to help you stay calm and comfortable during cataract surgery while you are awake. It may reduce pain and anxiety without extra medicine.
Los Angeles, CaliforniaAges Any age - NCT07329309Recruiting
Breathing exercises for pain after cesarean
This study tests if a gentle breathing technique called Pranayama can help reduce pain after a planned cesarean. It compares the breathing exercise to usual care to see if it improves recovery.
Konya, KonyaAges 18–35 - NCT07242170Recruiting
Comparing nerve blocks for pain after knee replacement surgery
This trial tests if adding extra nerve blocks (sciatic, BiFeS, or IPACK) to the usual adductor canal block can reduce pain after total knee replacement. The goal is to find a better way to manage pain and improve recovery.
Erzincan, MerkezAges 18–75 - NCT06676748RecruitingEarly Phase 1
Benzydamine gargle for sore throat after surgery
This trial tests whether a medicated mouthwash or gargle with benzydamine can help prevent a sore throat after surgery. It's for women having surgery with a type of breathing tube called a laryngeal mask airway.
SingaporeAges 21–80 - NCT05089994Recruiting
Pain-control injections after bladder surgery
This trial compares two different injection techniques to reduce pain after radical cystectomy (bladder removal surgery). It may help find which approach gives better pain relief with fewer side effects.
AsyutAges 40–70 - NCT03661645Enrolling by invitationPhase 4
Steroid dose taper after orthopedic surgery
This trial tests whether a planned, gradually stopping steroid medicine (methylprednisolone) after certain orthopedic surgeries helps with recovery or symptoms. It compares a post-surgery steroid taper to other routine care and focuses on safety and outcomes after surgery.
Atlanta, GeorgiaAges 18–95 - NCT07050277RecruitingPhase 3
Morphine for bladder issues after knee replacement
This study tests whether adding morphine to spinal anesthesia can reduce trouble urinating after a second knee replacement surgery. It may help you avoid needing a catheter after surgery.
Toronto, OntarioAges 21 years+ - NCT07453498Recruiting
Nerve block for pain after hip replacement
This study tests if a specific nerve block (the psoas sheath block) helps reduce pain after hip replacement surgery. If you are having a hip replacement, you may be able to join and get this extra pain relief.
GalwayAges 18 years+ - NCT04248205RecruitingPhase 4
Ketamine to reduce pain after hemorrhoid surgery
This trial tests whether ketamine can lessen pain after hemorrhoidectomy (surgery for severe hemorrhoids). It may help reduce how much pain medicine you need during recovery.
Oklahoma City, OklahomaAges 18–100 - NCT04791579RecruitingPhase 2
Preventing UTIs after Botox for neurogenic bladder
This study tests whether taking an antibiotic (ciprofloxacin) around the time of bladder Botox can prevent urinary tract infections (UTIs) in people whose bladder problems are caused by nerve conditions. It may help lower the chance of infection after treatment.
Edmonton, AlbertaAges 18–100 - NCT06952556RecruitingPhase 4
Comparing two types of knee blocks for pain after knee surgery
This trial tests if adding an extra nerve block behind the knee (IPACK) to the standard block inside the thigh (adductor canal) provides better pain relief after specific knee surgeries. It aims to help patients recover with less opioid use.
New York, New YorkAges 18–75 - NCT07110051Recruiting
Pain relief after abdominal surgery in children with cancer
This trial compares two pain medicines, nalbuphine and tramadol, to see which works better for children with cancer after abdominal surgery. The goal is to find the safest and most effective way to manage pain.
CairoAges 3–12 - NCT07218289Recruiting
Green light therapy for recovery after surgery
This study tests if exposing patients to green light after laparoscopic or robotic surgery can help reduce pain and improve recovery. You may be eligible if you are staying in the hospital for at least two days after your surgery.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07221682RecruitingPhase 2/Phase 3
Comparing two nerve block methods for lower leg surgery
This study compares two ways of giving a nerve block (fascia iliaca block) to help with positioning for spinal anesthesia and pain relief after lower leg surgery. The goal is to see which method works better for making patients more comfortable.
Sāhīwāl, Punjab ProvinceAges 30–60 - NCT07435675Recruiting
Nerve block to prevent agitation after ear surgery in children
This study tests if a nerve block behind the ear can help children ages 5–14 stay calm and comfortable after middle ear surgery. It may reduce confusion and restlessness when waking up from anesthesia.
Al Fayyum, Faiyum GovernorateAges 5–14 - NCT07514637RecruitingPhase 2
Pain relief medication after pancreas surgery
This study tests a new drug called Anricfen (ariceptin) to help reduce pain and speed recovery after pancreas removal surgery. Participants receive injections for three days after surgery to see if the medication safely controls pain better than standard care.
NanjingAges 18–80 - NCT06658210Recruiting
Soft tissue massage and pelvic exercises for pelvic scar tissue
This study tests whether gentle massage and pelvic floor exercises can help relieve pain and discomfort from pelvic scar tissue (adhesions) in women who have had a hysterectomy. It may be an option for you if you are married, between 40 and 60, and healthy enough for these treatments.
Lahore, Punjab ProvinceAges 40–60 - NCT07063602Recruiting
Comparing nerve block methods for pain after lung surgery
This study compares two ways of giving a paravertebral nerve block (an injection near the spine to numb the chest) to control pain after a type of lung surgery called VATS. It aims to find the best approach for reducing pain and the need for stronger pain medicines.
Montreal, QuebecAges 18 years+ - NCT04305743RecruitingPhase 4
Compare pain after 5 vs 20 bladder botox injections
This study looks at how much discomfort you have after receiving bladder Botox injections, comparing a smaller (5) dose vs a larger (20) dose. It’s only for certain overactive bladder conditions and specifically when the procedure is done without sedation or special anesthesia.
Washington D.C., District of ColumbiaAges 18 years+ - NCT04399707Recruiting
Nerve-pain device study for pain after C-section
This study tests whether a small skin electrical nerve stimulator (called TENS) can reduce pain after a planned or not-urgent C-section. You may be more likely to have less pain and use fewer pain medicines if the TENS helps you.
Honolulu, HawaiiAges 18 years+ - NCT07658521Enrolling by invitation
Nerve blocks for pain after heart bypass surgery
This study tests whether adding two numbing injections (nerve blocks) to standard care provides better pain relief after heart bypass surgery. It is for adults having planned surgery and compares pain scores and recovery.
Cairo, Cairo GovernorateAges 18–75 - NCT06903819RecruitingPhase 4
Ketamine for pain and mental health after orthopedic injury
This trial tests if ketamine can reduce pain, opioid use, and improve mental health in adults recovering from serious orthopedic injuries. It may help those with high injury severity scores.
Lubbock, TexasAges 18–65
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Common questions
- Are there clinical trials for post operative pain?
- Yes. Clin2 currently lists 197 recruiting post operative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a post operative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a post operative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.