Clinical trials
Post Operative Pain clinical trials
Below are recruiting post operative pain clinical trials, each written for real people, not researchers. We’re tracking 197 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07265557Recruiting
Comparing two pain plans after orthopedic surgery
This trial compares two different pain medication plans after major orthopedic surgery. It aims to find which plan helps you recover with less pain and fewer side effects.
Boston, MassachusettsAges 18 years+ - NCT04109638Recruiting
PEMF therapy to reduce pain after shoulder or knee surgery
This trial studies whether PEMF, a type of non-surgical device that uses pulsed electromagnetic fields, can reduce pain after shoulder or knee surgery. If you join, you’ll also be expected to do post-surgery physical therapy exercises and report your pain and function.
Redwood City, CaliforniaAges 18 years+ - NCT04912531Recruiting
Virtual reality and smell tools to ease surgery pain
This trial tests whether a combination of virtual reality and guided smells can reduce pain and anxiety around major heart and chest surgeries. If you’re scheduled for one of the listed operations, the study may help make recovery feel more comfortable by using sensory-based distraction.
Boston, MassachusettsAges 18 years+ - NCT06736483RecruitingPhase 2
Dexmedetomidine for children’s groin surgery recovery
This trial tests whether adding a sedative called dexmedetomidine to a numbing shot (nerve block) helps children aged 1–7 recover better after groin surgery. The goal is to improve comfort and reduce side effects.
Montpellier, FranceAges 1–7 - NCT06975761RecruitingPhase 2
Comparing two root canal fillings for pain
This study compares two types of root canal filling materials to see which one is better at reducing pain after the procedure. If you have a painful lower back tooth that needs a root canal and you are a healthy man aged 20-40, you may be able to join.
Rawalpindi, Punjab ProvinceAges 20–40 - NCT07153003Enrolling by invitationPhase 4
Tramadol and oxycodone vs oxycodone alone for joint pain
This trial tests if taking two pain relievers (tramadol and oxycodone) together works better than oxycodone alone to control pain after knee or hip replacement surgery. It aims to find a more effective way to manage pain with fewer side effects.
Rochester, MinnesotaAges 18 years+ - NCT06910540Recruiting
Acu-TENS for pain and stress in IVF
This trial tests if acu-TENS, a needle-free acupressure device, can reduce pain and stress in women before and during an embryo transfer procedure. It's designed for women going through IVF treatment.
Hong KongAges 18 years+ - NCT07360028Recruiting
Nerve blocks for pain after chest surgery
This trial tests two types of numbing injections (nerve blocks) to control pain after chest surgery done with a camera. It aims to find which block works better so you can recover more comfortably.
Cairo, Abbassia-EgyptAges 25–70 - NCT06471348Recruiting
Pain control after scoliosis surgery: comparing two numbing medicines
This study compares two types of numbing medicine used during scoliosis surgery to see which provides better pain relief after the operation. One is a long-acting version (liposomal bupivacaine) and the other is a standard short-acting mix (bupivacaine with epinephrine). If you are a teen having surgery for Adolescent Idiopathic Scoliosis, this trial may help find a way to reduce pain and possibly lessen the need for opioids afterward.
Boston, MassachusettsAges 10–17 - NCT07041736Recruiting
Laser combo for pain and infection after root canal
This trial tests if using ultrasound and a 980 nm diode laser together can reduce pain and kill bacteria better after a root canal. It may help if you have a tooth with an infection at the tip, but no symptoms.
CairoAges 20–35 - NCT07666646Recruiting
Nerve block comparison for lung function after gallbladder surgery
This trial compares two types of nerve blocks to see which one better preserves lung function after laparoscopic gallbladder removal. It may help patients recover breathing ability more quickly after surgery.
Kayseri, KocasinanAges 18–70 - NCT05072314RecruitingPhase 3
Lidocaine drip after breast surgery to improve long-term pain
This Phase 3 study tests whether a long-running lidocaine (a numbing medicine) drip given around the time of breast surgery can improve long-term post-surgery pain and recovery. It may help people who have pain after mastectomy or breast-conserving surgery.
Kingswood, New South WalesAges 18 years+ - NCT06979583Enrolling by invitation
Stent and sheath size and pain after kidney stone surgery
This study compares whether the size of the stent and the sheath used during kidney stone surgery affects how much pain you feel afterward. If you are having a stone removal procedure and will get a stent with a string, you may be able to join.
Rochester, MinnesotaAges 18 years+ - NCT07577908Recruiting
Pain Relief Methods for Minimally Invasive Lung Surgery
This study compares two methods of numbing nerves to reduce pain after minimally invasive lung surgery (VATS). Researchers will test which approach works better for keeping you comfortable after your operation.
İzmitAges 18–80 - NCT06640218Recruiting
Comparing two ultrasound tools for tooth pain after root canal
This trial tests two different ultrasound methods used during root canal treatment to see which one reduces pain better afterwards. It focuses on people with a specific kind of tooth pain and infection.
Cairo, New CairoAges 18–40 - NCT06513208RecruitingPhase 4
Ketorolac for pain after lower back fusion surgery
This trial tests if a non-steroidal anti-inflammatory drug (NSAID) called ketorolac can help reduce pain after lower back fusion surgery. It is for people who are having elective surgery to fuse one or two bones in their lower back.
Towson, MarylandAges 18–85 - NCT05854914Recruiting
Smartphone hypnosis to reduce pain after emergency appendix surgery
This study tests whether guided hypnosis on a smartphone can lower pain after emergency surgery for a complicated appendicitis. If you qualify, you’ll use the app during your recovery and also answer quick questions about your pain and anxiety.
NiceAges 18 years+ - NCT03759028RecruitingPhase 4
Study of pain relief after elbow fracture surgery
This trial looks at how well different pain medicines work after surgery for a specific type of broken elbow bone. It may help find a safer, more comfortable pain-control plan while the fracture heals.
Los Angeles, CaliforniaAges 4–12 - NCT05110989Recruiting
Registry study of pain relief after freezing intercostal nerves
This study collects real-world information about how well freezing (cryoablation) of the intercostal nerves helps with pain after a procedure. It may help doctors understand outcomes and improve care for future patients.
Jacksonville, FloridaAges 12 years+ - NCT05141591Recruiting
Anxiety before ENT surgery and opioid use after surgery
This trial looks at whether people’s anxiety before ear, nose, and throat (ENT) surgery affects how much pain medicine (opioids) they need after surgery. It may help doctors better plan pain control based on anxiety level and possibly gender-related patterns.
Vienna, State of ViennaAges 18 years+ - NCT05150795RecruitingEarly Phase 1
Testing pregabalin before surgery versus fentanyl during surgery
This trial compares two medicines used around the time of surgery—pregabalin given by mouth before surgery versus fentanyl given during surgery—to see which better controls pain after the operation. You might join if you’re a generally healthy surgical patient and aren’t using certain related medicines.
CairoAges 21–45 - NCT05179928Recruiting
Numbing injections for less pain after belly surgery
This trial compares two different numbing injection techniques to help control pain after surgery above the belly button. It may help people who qualify have better or longer-lasting pain relief with fewer side effects.
Damanhūr, El-BeheiraAges 21–60 - NCT05783245Recruiting
Cooling therapy to reduce pain after open carpal tunnel surgery
This trial studies whether cooling (cold therapy) can lessen pain after open carpal tunnel release surgery. If you’re having this surgery, your answers to questionnaires and your current pain-medication status will determine whether you can join.
Chicago, IllinoisAges 18 years+ - NCT05860712Recruiting
Cinnamon vs chlorine rinse after baby tooth nerve treatment
This trial tests whether a cinnamon extract rinse works as well as a chlorine-based rinse to reduce pain and fight infection after pulpectomy (removing the nerve tissue) in baby teeth. It may help you understand which rinse causes less post-treatment discomfort.
CairoAges 4–8
Hear when a new Post Operative Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for post operative pain?
- Yes. Clin2 currently lists 197 recruiting post operative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a post operative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a post operative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.