Clinical trials
Post Operative Pain clinical trials
Below are recruiting post operative pain clinical trials, each written for real people, not researchers. We’re tracking 185 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07800364Recruiting
Tizanidine before leg surgery for better pain and sleep
This study tests whether taking a muscle relaxant called tizanidine before leg surgery improves pain control and sleep quality after the operation. It may help you recover more comfortably.
Tanta, Gharbia GovernorateAges 21 years+ - NCT07360028Recruiting
Nerve blocks for pain after chest surgery
This trial tests two types of numbing injections (nerve blocks) to control pain after chest surgery done with a camera. It aims to find which block works better so you can recover more comfortably.
Cairo, Abbassia-EgyptAges 25–70 - NCT07041736Recruiting
Laser combo for pain and infection after root canal
This trial tests if using ultrasound and a 980 nm diode laser together can reduce pain and kill bacteria better after a root canal. It may help if you have a tooth with an infection at the tip, but no symptoms.
CairoAges 20–35 - NCT06471348Recruiting
Pain control after scoliosis surgery: comparing two numbing medicines
This study compares two types of numbing medicine used during scoliosis surgery to see which provides better pain relief after the operation. One is a long-acting version (liposomal bupivacaine) and the other is a standard short-acting mix (bupivacaine with epinephrine). If you are a teen having surgery for Adolescent Idiopathic Scoliosis, this trial may help find a way to reduce pain and possibly lessen the need for opioids afterward.
Boston, MassachusettsAges 10–17 - NCT06426251Recruiting
Light therapy for knee replacement recovery
This trial tests whether a special light therapy (photobiomodulation) can help reduce pain and speed healing after total knee replacement. If you're having knee replacement and don't have complications like infection or open wounds, you may be eligible.
HsinchuAges 20 years+ - NCT07850258Recruiting
Laser vs standard treatment for severe tooth pain
This study compares two ways to treat a severely inflamed tooth nerve (pulpitis) that causes ongoing pain. One method uses a laser, while the other uses standard tools, to see which is better at relieving pain and saving the tooth.
Kütahya, MerkezAges 12–40 - NCT07800403Recruiting
Nanoparticle disinfection for root canal infection in diabetes
This trial tests a new disinfection approach during root canal treatment for people with type 2 diabetes who have an infected front tooth. It aims to improve the effectiveness of the cleaning step, which may help treat the infection better.
MinyaAges 18–40 - NCT07788027Recruiting
Comparing two root canal cleaning methods for reducing post-procedure discomfort
This study compares two different methods of delivering a cleaning solution during root canal treatment to see which one causes less pain and discomfort after the procedure. Participants will be randomly assigned to one of the two methods.
MinyaAges 18–45 - NCT07789548RecruitingPhase 4
Lower dose neck block for thyroid surgery
This study compares two doses of a numbing medicine injected near the nerves in your neck before thyroid surgery. The goal is to see if a lower dose provides enough pain relief with fewer side effects, such as affecting your breathing.
AsyutAges 18–65 - NCT06317870Recruiting
Nerve block vs spinal morphine for hip surgery pain
This trial compares two types of pain relief after a hip replacement: a nerve block (injecting numbing medicine near the hip) versus a small dose of morphine given through a spinal needle. It aims to find out which option works better with fewer side effects.
Lausanne, Canton of VaudAges 18 years+ - NCT07666646Recruiting
Nerve block comparison for lung function after gallbladder surgery
This trial compares two types of nerve blocks to see which one better preserves lung function after laparoscopic gallbladder removal. It may help patients recover breathing ability more quickly after surgery.
Kayseri, KocasinanAges 18–70 - NCT06662617Recruiting
Numbing injections for pain after gallbladder surgery
This study tests whether two different numbing injections (M-TAPA and TAPB) placed before surgery can reduce pain after keyhole gallbladder removal, compared to standard care. If you qualify, the injections may help you feel less discomfort after the operation.
SivasAges 18–80 - NCT07571837Recruiting
Nano-medication to reduce inflammation after root canal retreat
This study tests a special nano-sized (extremely tiny) medication placed inside a tooth after a previous root canal treatment failed. The goal is to reduce inflammation and swelling in the bone around the tooth's tip so it can heal better.
Cairo, Nasr CityAges 20–40 - NCT06191159Recruiting
Comparing scar looks after different mastectomy incision methods
This trial compares three different ways surgeons make the incision (cut) during a mastectomy to see which one leads to the best-looking scar. You may be eligible if you are having a mastectomy without immediate reconstruction.
Vancouver, British ColumbiaAges Any age - NCT07556536Recruiting
Nerve block comparison for kidney removal surgery pain
This trial tests two different types of numbing injections (nerve blocks) to see which one works better at controlling pain after open kidney removal surgery. You would receive one of these blocks during surgery to help reduce pain and the amount of strong pain medication you need afterward.
Al FayyumAges 18–65 - NCT06740903RecruitingPhase 2/Phase 3
Comparing two drugs for pain control in gallbladder surgery
This study compares two medications, dexmedetomidine and lignocaine, to see which works better for pain management during and after laparoscopic gallbladder removal. It may help improve comfort and recovery for people having this surgery.
Sahiwal, Punjab ProvinceAges 20–70 - NCT06741696Recruiting
Saline rinsing after wisdom tooth removal
This trial tests whether using saline (salt water) at different temperatures after wisdom tooth surgery helps with healing and pain. It could help you recover more comfortably.
Rawalpindi, Punjab ProvinceAges Up to 59 years - NCT07546903Recruiting
Pain relief methods for hip fracture surgery
This study compares two types of numbing injections (nerve blocks) used to reduce pain after hip fracture surgery. Researchers want to see which method works better to help patients recover with less pain.
ÇorumAges 18 years+ - NCT07539623RecruitingPhase 3
Pain relief with suzetrigine after heart or weight-loss surgery
This study tests whether suzetrigine, a new pain medication, can reduce the need for opioids (strong painkillers) after cardiac or bariatric surgery. The goal is to help patients manage pain with fewer opioid-related side effects.
New York, New YorkAges 18–85 - NCT07540689Recruiting
Pain Relief Method for Children's Minimally Invasive Belly Surgery
This study tests a new pain-relief technique called M-TAPA for children ages 1–7 having small-incision belly surgery. Researchers want to see if this method helps reduce pain better than standard approaches after surgery.
Cairo, ElmanialAges 1–7 - NCT07513012Enrolling by invitation
Pain Relief Methods After Gallbladder Removal Surgery
This study compares two ways of numbing the abdomen during gallbladder removal surgery to see which one works better for pain relief. One method numbs one side of your belly, and the other numbs both sides.
Lahore, Punjab ProvinceAges 18–80 - NCT07485803RecruitingPhase 4
Methadone for pain after knee replacement
This study tests whether methadone, a type of pain medicine, helps control pain better after knee replacement surgery. It is for people who have not used narcotics recently and are otherwise healthy.
Denver, ColoradoAges 21–75 - NCT05150795RecruitingEarly Phase 1
Testing pregabalin before surgery versus fentanyl during surgery
This trial compares two medicines used around the time of surgery—pregabalin given by mouth before surgery versus fentanyl given during surgery—to see which better controls pain after the operation. You might join if you’re a generally healthy surgical patient and aren’t using certain related medicines.
CairoAges 21–45 - NCT07434583Recruiting
Force sensor study for laryngeal surgery patients
This trial tests a force sensor tool used during laryngeal surgery (surgery on the voice box) via direct laryngoscopy (a tube inserted through the mouth). It may help surgeons apply the right amount of force to reduce tongue injuries.
San Francisco, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for post operative pain?
- Yes. Clin2 currently lists 185 recruiting post operative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a post operative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a post operative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.