Clinical trials
Post Operative Pain clinical trials
Below are recruiting post operative pain clinical trials, each written for real people, not researchers. We’re tracking 197 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06812832RecruitingPhase 4
Simethicone in bariatric surgery recovery
This trial tests if giving simethicone (a gas-relief medication) as part of a standard recovery plan helps patients feel better after weight-loss surgery. It may reduce bloating and discomfort after surgery.
Tacoma, WashingtonAges 18–89 - NCT06836882Recruiting
Testing cavity disinfectants for deep tooth decay pain
This study tests two cavity disinfectants to see which one better reduces pain and improves healing after removing deep decay from back teeth. It is for adults with deep cavities in their lower molars that are still alive (not needing a root canal).
HaryānaAges 18 years+ - NCT06852248Recruiting
Green dye vs. ureter stent for endometriosis surgery
This trial compares two ways of protecting the ureter during deep endometriosis surgery: placing a small tube (stent) versus using a green dye (indocyanine green) to see the ureter. The goal is to see if the dye works just as well but causes less pain and fewer side effects afterward.
Stoke-on-Trent, StaffordshireAges 18–50 - NCT06864884RecruitingEarly Phase 1
Study of ARC-001 for wisdom teeth removal
This trial tests a new medicine called ARC-001 in people who are scheduled to have their wisdom teeth taken out. The goal is to see if it's safe and how it affects pain and healing.
Salt Lake City, UtahAges 18–55 - NCT06873893Recruiting
Nerve blocks for pain relief after mastectomy surgery
This study compares two types of ultrasound-guided nerve blocks to see which one provides better pain relief after a mastectomy. The blocks are injected near the chest wall to numb the area during and after surgery.
Cairo , AbbassyaAges 35–65 - NCT06982625Recruiting
Numbing injection after hip replacement for pain relief
This trial tests whether an injection of numbing medicine near the hip can help control pain after a hip replacement surgery. It may be an option for people who have significant pain after their operation.
ParisAges 18 years+ - NCT06991231Recruiting
Cryoablation benefits in knee replacement surgery
This trial tests if a special cold treatment (cryoablation) can help reduce pain or improve recovery for people getting knee replacement surgery for arthritis. It might offer an extra option to feel better after the procedure.
New York, New YorkAges 18 years+ - NCT07034300RecruitingPhase 4
Comparing lidocaine with and without dexmedetomidine for arm surgery
This trial tests whether adding dexmedetomidine to lidocaine works better for numbing the arm during surgery. Patients get numbing medicine through a special IV in the arm while the surgery is happening.
Lahore, Punjab ProvinceAges 18–60 - NCT07075055Recruiting
New bioceramic medication for infected front teeth
This trial tests a new bioceramic medication placed inside the root canal of infected front teeth to see if it improves healing. It is for adults with mature front teeth and an infection around the root tip, who are otherwise healthy.
MinyaAges 18–40 - NCT07094386Recruiting
Pain relief study after open upper abdominal surgery
This trial compares two types of nerve blocks to control pain after open upper abdominal surgery. It aims to find which block works better and may help you recover with less pain.
CairoAges 18–60 - NCT07095556Recruiting
Laser therapy to help gums heal after tooth extraction
This trial tests whether a special laser treatment can help your gums heal better after a tooth is removed and the socket is prepared for a future dental implant. If you're having a tooth pulled and bone preservation, this laser might speed up healing and reduce pain.
Charleston, South CarolinaAges 18 years+ - NCT07202416Recruiting
Pain relief after c-section: nerve block vs spinal morphine
This study compares two ways to manage pain after a planned cesarean section: a nerve block near the spine (ESPB) versus morphine injected into the spinal fluid. The goal is to find which method helps mothers recover more comfortably.
Cesena, ForlìAges 18–45 - NCT07210164Recruiting
Pre-surgery wellness program for gynecologic cancer surgery
This trial tests whether a pre-surgery wellness program (pre-habilitation) within an enhanced recovery protocol helps women recover better after surgery for endometrial, ovarian, or cervical cancer. It is designed for women who are having open abdominal surgery (laparotomy).
ThessalonikiAges 18–85 - NCT07222072RecruitingPhase 4
Methadone to reduce opioid use after spine surgery
This study tests whether giving methadone during and after major spine surgery can help reduce the need for other opioid pain medicines later. It is for adults having multilevel fusion in the lower or mid-back.
Cleveland, OhioAges 18–72 - NCT07281118Recruiting
Nerve freezing for pain after double lung transplant
This trial tests a procedure called intercostal cryoanalgesia, which freezes nerves in the chest to reduce pain after a double lung transplant. It may help you feel less pain and use fewer painkillers after surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT07375576Recruiting
Comparing partial nerve removal to root canal for severe tooth pain
This study compares two ways to treat severe tooth pain from advanced decay: a partial nerve removal (pulpotomy) versus a full root canal treatment. It aims to find which approach works better for saving the tooth.
Hatay, AntakyaAges 18–45 - NCT07434583Recruiting
Force sensor study for laryngeal surgery patients
This trial tests a force sensor tool used during laryngeal surgery (surgery on the voice box) via direct laryngoscopy (a tube inserted through the mouth). It may help surgeons apply the right amount of force to reduce tongue injuries.
San Francisco, CaliforniaAges 18 years+ - NCT07485803RecruitingPhase 4
Methadone for pain after knee replacement
This study tests whether methadone, a type of pain medicine, helps control pain better after knee replacement surgery. It is for people who have not used narcotics recently and are otherwise healthy.
Denver, ColoradoAges 21–75 - NCT07539623RecruitingPhase 3
Pain relief with suzetrigine after heart or weight-loss surgery
This study tests whether suzetrigine, a new pain medication, can reduce the need for opioids (strong painkillers) after cardiac or bariatric surgery. The goal is to help patients manage pain with fewer opioid-related side effects.
New York, New YorkAges 18–85 - NCT07540689Recruiting
Pain Relief Method for Children's Minimally Invasive Belly Surgery
This study tests a new pain-relief technique called M-TAPA for children ages 1–7 having small-incision belly surgery. Researchers want to see if this method helps reduce pain better than standard approaches after surgery.
Cairo, ElmanialAges 1–7 - NCT07546903Recruiting
Pain relief methods for hip fracture surgery
This study compares two types of numbing injections (nerve blocks) used to reduce pain after hip fracture surgery. Researchers want to see which method works better to help patients recover with less pain.
ÇorumAges 18 years+ - NCT07556536Recruiting
Nerve block comparison for kidney removal surgery pain
This trial tests two different types of numbing injections (nerve blocks) to see which one works better at controlling pain after open kidney removal surgery. You would receive one of these blocks during surgery to help reduce pain and the amount of strong pain medication you need afterward.
Al FayyumAges 18–65 - NCT07571837Recruiting
Nano-medication to reduce inflammation after root canal retreat
This study tests a special nano-sized (extremely tiny) medication placed inside a tooth after a previous root canal treatment failed. The goal is to reduce inflammation and swelling in the bone around the tooth's tip so it can heal better.
Cairo, Nasr CityAges 20–40 - NCT07513012Enrolling by invitation
Pain Relief Methods After Gallbladder Removal Surgery
This study compares two ways of numbing the abdomen during gallbladder removal surgery to see which one works better for pain relief. One method numbs one side of your belly, and the other numbs both sides.
Lahore, Punjab ProvinceAges 18–80
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Common questions
- Are there clinical trials for post operative pain?
- Yes. Clin2 currently lists 197 recruiting post operative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a post operative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a post operative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.