Clinical trials
Post Operative Pain clinical trials
Below are recruiting post operative pain clinical trials, each written for real people, not researchers. We’re tracking 185 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06671002RecruitingPhase 4
Pain medicine safety study for kids having surgery
This study compares different pain medicines to see which works best and is safest for children after surgery for tonsil removal, gallbladder removal, or knee arthroscopy. It aims to help find the most effective and least risky pain control option.
Los Angeles, CaliforniaAges 12–20 - NCT06653803Recruiting
Nerve blocks for pain after chest wall surgery
This trial compares two types of nerve blocks (rhomboid intercostal and retrolaminar) to see which provides better pain relief after a type of chest surgery called thoracoscopic sympathectomy. If you are having this surgery, you may be eligible to join.
Damanhūr, El-BeheiraAges 18–60 - NCT06639438Recruiting
Sensory outcomes in people who use opioids
This study looks at how opioids affect the senses in people having planned surgery. Researchers want to compare patients who use opioids (for pain or addiction) with those who don't, to see if there are differences in sensation.
Boston, MassachusettsAges 18 years+ - NCT06568770RecruitingPhase 2/Phase 3
Comparing two nerve blocks for femur fracture surgery pain
This trial tests if one type of nerve block (PENG block) works better than another (S-FICB) for controlling pain during and after femur fracture surgery. Both blocks are guided by ultrasound to help with your recovery.
Sahiwal, Punjab ProvinceAges 20–70 - NCT05854914Recruiting
Smartphone hypnosis to reduce pain after emergency appendix surgery
This study tests whether guided hypnosis on a smartphone can lower pain after emergency surgery for a complicated appendicitis. If you qualify, you’ll use the app during your recovery and also answer quick questions about your pain and anxiety.
NiceAges 18 years+ - NCT06513208RecruitingPhase 4
Ketorolac for pain after lower back fusion surgery
This trial tests if a non-steroidal anti-inflammatory drug (NSAID) called ketorolac can help reduce pain after lower back fusion surgery. It is for people who are having elective surgery to fuse one or two bones in their lower back.
Towson, MarylandAges 18–85 - NCT06425016Recruiting
Robot-assisted vs. traditional sleeve gastrectomy
This study compares two types of weight-loss surgery: one done with the help of a robot and the other done by hand (laparoscopic). Both are types of sleeve gastrectomy, where the stomach is reduced in size. If you qualify for sleeve gastrectomy, this trial may help doctors learn which method works better.
Cleveland, OhioAges 18–70 - NCT06434233RecruitingPhase 4
Opioid use after fallopian tube removal surgery
This study looks at how much opioid pain medicine people need after having their fallopian tubes removed through small incisions (laparoscopic or robotic salpingectomy). It aims to see if the usual pain medicine can be reduced to decrease opioid use.
Baltimore, MarylandAges 18 years+ - NCT06418958Recruiting
Heat from dental light on healthy teeth
This trial measures how much the temperature rises inside a healthy tooth when a dental curing light is used. It helps dentists understand if certain light wavelengths could be safer for teeth.
Gainesville, FloridaAges 21–35 - NCT06420336Recruiting
Pain relief after cleft palate surgery
This study compares two ways to manage pain after cleft palate repair surgery that uses a bone graft from the hip. The goal is to see which method provides better pain control for children and teens.
Charleston, South CarolinaAges 6–18 - NCT05868330RecruitingPhase 4
Compare two nerve-block methods for shoulder replacement
This trial compares two different ways of giving numbing medicine around the shoulder nerve before reverse shoulder replacement surgery. It may help find which method works better for pain control and comfort after surgery.
Iowa City, IowaAges 18–90 - NCT05876390Enrolling by invitation
Regional anesthesia to reduce long-term breast surgery pain
This trial studies whether a pain-control technique called regional anesthesia during certain breast surgeries can lower chronic (long-lasting) pain after surgery. It may help improve comfort and quality of life for people at risk of ongoing pain after their breast operation.
Milan, LombardyAges 18 years+ - NCT05783245Recruiting
Cooling therapy to reduce pain after open carpal tunnel surgery
This trial studies whether cooling (cold therapy) can lessen pain after open carpal tunnel release surgery. If you’re having this surgery, your answers to questionnaires and your current pain-medication status will determine whether you can join.
Chicago, IllinoisAges 18 years+ - NCT05585788Recruiting
Opioid pain device test for cancer surgery patients
This study tests a device that helps you safely use opioid (strong pain) medicine after major cancer surgery. It may help improve post-surgery pain control while tracking how people use the medicine.
New York, New YorkAges 18–99 - NCT05179928Recruiting
Numbing injections for less pain after belly surgery
This trial compares two different numbing injection techniques to help control pain after surgery above the belly button. It may help people who qualify have better or longer-lasting pain relief with fewer side effects.
Damanhūr, El-BeheiraAges 21–60 - NCT05110989Recruiting
Registry study of pain relief after freezing intercostal nerves
This study collects real-world information about how well freezing (cryoablation) of the intercostal nerves helps with pain after a procedure. It may help doctors understand outcomes and improve care for future patients.
Jacksonville, FloridaAges 12 years+ - NCT05072314RecruitingPhase 3
Lidocaine drip after breast surgery to improve long-term pain
This Phase 3 study tests whether a long-running lidocaine (a numbing medicine) drip given around the time of breast surgery can improve long-term post-surgery pain and recovery. It may help people who have pain after mastectomy or breast-conserving surgery.
Kingswood, New South WalesAges 18 years+ - NCT03759028RecruitingPhase 4
Study of pain relief after elbow fracture surgery
This trial looks at how well different pain medicines work after surgery for a specific type of broken elbow bone. It may help find a safer, more comfortable pain-control plan while the fracture heals.
Los Angeles, CaliforniaAges 4–12 - NCT07507799Recruiting
Comparing low vs standard dose block for gallbladder surgery
This trial tests two different amounts of a numbing medicine (local anesthetic) given during gallbladder removal surgery. The goal is to see if a lower dose works just as well for pain control.
El Fayoum Qesm, Faiyum GovernorateAges 18–65 - NCT07388953Recruiting
Nerve block for better pain relief after colon surgery
This study tests adding a special nerve block (peripheral autonomic block) to a standard abdominal wall block to see if it provides better pain relief after minimally invasive left-sided colon surgery. It may help patients experience less pain and use fewer pain medications.
Belo Horizonte, Minas GeraisAges 18–80 - NCT07066709RecruitingPhase 2
Hip pain study after hip surgery
This study tests if a second hip surgery can help people who still have pain at least 6 months after their first hip surgery. It may help you if you have ongoing hip pain and haven't needed strong pain pills.
Madison, WisconsinAges 18–45 - NCT06635889RecruitingPhase 2
Numbing medicine in bladder after kidney stone surgery
This study tests whether numbing medicine placed directly into the bladder can reduce pain after a ureteroscopy procedure for kidney stones. It may help you feel better and use less pain medication after surgery.
Chicago, IllinoisAges 18 years+ - NCT05492188Recruiting
Testing training and skin reflex changes for nerve pain after SCI
This study looks at how a training program affects skin reflexes and nerve pain in people with spinal cord injury (SCI). It may help researchers find better ways to manage nerve pain by changing how the body responds to touch and training.
Charleston, South CarolinaAges 18 years+ - NCT07528482Recruiting
Reflexology and cold therapy for chest tube removal pain
This study tests whether foot massage (reflexology) and cold application can reduce pain when chest tubes are removed after heart bypass surgery. Researchers want to see if these complementary techniques help manage discomfort during this procedure.
AnkaraAges 18 years+
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Common questions
- Are there clinical trials for post operative pain?
- Yes. Clin2 currently lists 185 recruiting post operative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a post operative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a post operative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.