Clinical trials
Postoperative Analgesia clinical trials
Below are recruiting postoperative analgesia clinical trials, each written for real people, not researchers. We’re tracking 175 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06183528Recruiting
Numbing shot for recovery after hip replacement
This study looks at a special numbing shot around the hip joint to see if it helps people recover faster and feel better after total hip replacement surgery. It may help reduce pain and improve your recovery.
Istanbul, UmraniyeAges 40–85 - NCT06271265RecruitingPhase 1
Testing EXPAREL for pain after heart surgery in children
This study tests a long-acting pain medicine (EXPAREL) given during heart surgery to see how it works in young children. The goal is to help control pain after surgery with fewer side effects.
Indianapolis, IndianaAges birth–6 years - NCT07335250Recruiting
Nerve block for pain after lung surgery
This study tests a nerve block (an injection near the spine) to see if it reduces pain after lung surgery (thoracotomy with lobectomy). If you are having planned lung surgery, this could help manage your pain with fewer side effects.
KonyaAges 18–85 - NCT07527065Enrolling by invitation
Pain Relief Methods for Hernia Surgery Recovery
This study compares two different nerve-blocking injection techniques to help manage pain after open inguinal hernia repair surgery. The goal is to determine which method works better to keep you comfortable during recovery.
ÇorumAges 18–65 - NCT07331441Recruiting
Nerve block for pain relief after major upper abdominal surgery
This trial tests a nerve block given near the ribs to see if it reduces pain after surgeries like gastric, liver, gallbladder, or pancreatic surgery. It may help you need less pain medicine after the operation.
ShanghaiAges 18–85 - NCT07504705Recruiting
Comparing two nerve blocks for pain after gallbladder surgery
This trial compares two types of nerve blocks (intertransverse process block and erector spinae plane block) to see which provides better pain relief after gallbladder removal surgery using small incisions (laparoscopic cholecystectomy).
Konya, KonyaAges 18 years+ - NCT06753500RecruitingPhase 4
Numbing medicine during gallbladder surgery
This trial tests whether giving a special numbing medicine during gallbladder surgery helps reduce pain. It is for adults having laparoscopic (minimally invasive) gallbladder removal.
Barranquilla, AtlantivoAges 18 years+ - NCT07360392Recruiting
Nerve block comparison for knee replacement pain
This study compares two numbing techniques (nerve blocks) for pain relief after knee replacement surgery. The goal is to find which one works better and helps you recover with less pain.
AmasyaAges 18–80 - NCT07740915Enrolling by invitation
Pain relief after heart surgery in children
This study compares two types of pain blocks for children having heart surgery for the first time. The goal is to see which block provides better pain relief after surgery, which could help your child recover more comfortably.
Diyarbakır, DiyarbakırAges birth–18 years - NCT06665438RecruitingPhase 3
Pain relief after knee arthroscopy: numbing injection with added medication
This trial tests whether adding dexmedetomidine to a numbing injection (bupivacaine) inside the knee joint provides better pain relief after arthroscopic ACL reconstruction. It aims to help patients recover more comfortably after surgery.
AsyutAges 18–65 - NCT07328893RecruitingPhase 4
Magnesium for pain after gallbladder surgery
This trial tests whether a single dose of magnesium (given through an IV before surgery) can reduce the need for painkillers after gallbladder removal surgery. If you are a healthy adult getting this surgery, you may experience less pain and use fewer pain medications.
Jamshedpur, JharkhandAges 18–65 - NCT06015165Recruiting
Pain control plan for complex anorectal surgery
This study tests a pain management plan led by anesthesiologists for people having complex anorectal surgery. The goal is to see if this approach can better control pain and improve recovery.
Beijing, Beijing MunicipalityAges 18–85 - NCT06271174RecruitingPhase 3
Preventing long-term pain after child surgery
This study tests whether a pain block (medicine injected near nerves) can prevent long-term pain after a child's bone or joint surgery. It aims to help children have less pain months later.
NantesAges 5 years–15.3 years - NCT07672015RecruitingPhase 4
Testing a new pain drug in surgery patients at risk for opioid dependence
This trial tests a new painkiller called suzetrigine for post-surgery pain. It's designed for people whose medical records suggest they may have a higher chance of needing strong painkillers (opioids) long after surgery. We want to see if suzetrigine works better at preventing that.
La Jolla, CaliforniaAges 18 years+ - NCT06522620Recruiting
Nerve block for knee pain after total knee replacement
This trial tests whether a nerve block can reduce pain on the back and outer side of the knee after total knee replacement surgery. If effective, it may help you recover more comfortably.
Yinchuan, NingxiaAges 45–80 - NCT05504265RecruitingPhase 2/Phase 3
Pain control methods during minimally invasive esophagus surgery
This study compares different ways to control pain around the time of minimally invasive esophagus surgery. It may help find a method that controls pain better and improves recovery after surgery.
BeijingAges 18–75 - NCT07779551Enrolling by invitation
Pain relief after thyroid surgery: comparing two numbing drugs
This study compares two medications, bupivacaine and ropivacaine, given as a neck block before thyroid surgery to see which provides better pain relief after the operation. It may help reduce post-surgery discomfort.
Sargodha, Punjab ProvinceAges 20–40 - NCT07566663Recruiting
Pain Relief Before Gallbladder Removal Surgery
This study tests whether a pain-relief medication called Anrikefon, given before laparoscopic gallbladder removal surgery, helps reduce pain after the procedure. Laparoscopic surgery uses small cuts and a camera, so it's less invasive than open surgery.
Beijing, Beijing MunicipalityAges 18–65 - NCT06409689Recruiting
Oliceridine for pain relief after upper abdominal surgery
This study tests a new pain medicine called oliceridine after laparoscopic upper abdominal surgery. It aims to improve pain control and recovery compared to standard opioids.
Wuhan, HubeiAges 18–70 - NCT07388745Recruiting
Comparing two pain blocks for heart bypass surgery
This study compares two different nerve-block injections (one near the spine, one under the shoulder blade) to see which provides better pain relief after heart bypass surgery. If you are scheduled for a planned bypass and are in reasonably good health, you might be able to join.
KütahyaAges 45–85 - NCT07353996RecruitingPhase 4
Finding the right dose of a new IV painkiller after bone surgery
This trial tests a single dose of a new pain medicine called tegileridine fumarate given through a vein right after orthopedic surgery (like spine, hip, or knee surgery). The goal is to find the best dose that works well for pain without causing side effects.
Hanzhong, ZhejiangAges 18–75 - NCT06936995Recruiting
Comparing pain relief methods for ACL surgery recovery
This trial tests two ways to manage pain after ACL reconstruction: a combination of medications (multimodal analgesia) versus a nerve block in the thigh (femoral block). The goal is to see which approach provides better pain control and recovery.
AnkaraAges 18–65 - NCT06765772Recruiting
Nerve blocks for pain relief during tummy tuck surgery
This trial compares two types of nerve blocks (with numbing medicine) to reduce pain during and after tummy tuck surgery. The goal is to see if combining two blocks works better than one block alone.
Cairo, Cairo GovernorateAges 21–60 - NCT07479446Recruiting
Comparing two painkillers for nausea after brain surgery
This trial tests if a newer painkiller (oliceridine) causes less nausea after a specific type of brain surgery than the standard painkiller (sufentanil). If you are having CPA region surgery and will receive a patient-controlled pain pump, this study may help find a better option for managing pain with fewer side effects.
BeijingAges 18–65
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Common questions
- Are there clinical trials for postoperative analgesia?
- Yes. Clin2 currently lists 175 recruiting postoperative analgesia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative analgesia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative analgesia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.