Clinical trials
Postoperative Pain, Acute clinical trials
Below are recruiting postoperative pain, acute clinical trials, each written for real people, not researchers. We’re tracking 91 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06774274RecruitingPhase 4
Ketamine for pain after major orthopedic surgery: drip vs. pump
This study tests two ways of giving a medicine called ketamine to control pain after major bone or joint surgery. One method is a steady infusion (drip) through a vein, and the other is a patient-controlled pump (PCA) that lets you press a button for more medicine when you need it.
Medellín, AntioquiaAges 18 years+ - NCT07198412Recruiting
Study on sedation's effect on back pain after spinal anesthesia
This study looks at whether giving sedation (medicine to help you relax) during spinal anesthesia can reduce back pain after surgery. It's for people having certain types of surgery on their lower abdomen or legs.
Banhā, Qalyubia GovernorateAges 18–65 - NCT07147049RecruitingPhase 2
Testing a new painkiller for moderate to severe pain after surgery
This trial tests a new tablet called HL-1186 for people with moderate to severe pain after certain surgeries. It aims to see if the drug is safe and works well for pain control.
Chengdu, SichuanAges 18–75 - NCT07048522Recruiting
Nimodipine before bowel cancer surgery
This trial tests if giving nimodipine before and after surgery for bowel cancer can help improve recovery and reduce pain. It may be a good fit if you meet the age and health requirements.
Pátrai, AchaeaAges 18–75 - NCT07023497Recruiting
Finding the best dose of spinal morphine for C-section pain relief
This study tests different doses of morphine given through a spinal injection during a planned C-section to find the best balance of pain relief and side effects. It may help women have better pain control after surgery.
Ioannina, EpirusAges 18–50 - NCT06569953RecruitingPhase 4
Numbing Medicine for Pain After Lung Surgery
This study tests whether a long-lasting numbing medicine (liposomal bupivacaine) injected near the spine can better control pain after lung surgery. It compares this to a standard numbing medicine, and aims to help patients recover with less pain after surgery.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06865378Enrolling by invitation
Breathing gas and nausea after hysterectomy study
This study looks at whether levels of carbon dioxide in your breath and blood flow measurements during surgery can help predict nausea, vomiting, or pain after a hysterectomy. It may help doctors better manage your recovery.
IstanbulAges 20–65 - NCT05906134RecruitingPhase 1/Phase 2
Pain control plan after minimally invasive esophagus surgery
This trial tests a pain-control method (using an epidural/nerve pain-block through the back, called neuraxial anesthesia) for people having minimally invasive esophagus removal surgery. It may help reduce pain after surgery and improve comfort during recovery.
Seattle, WashingtonAges 18 years+ - NCT06602271RecruitingPhase 3
Study of PF614 for Pain After Tummy Tuck Surgery
This study tests a new painkiller called PF614 for pain after tummy tuck surgery. It compares the study drug to a placebo (a pill with no medicine) to see how well it works and how safe it is.
Atlanta, GeorgiaAges 18–75 - NCT06555107Recruiting
Pain before emergency surgery and long-term pain after
This study looks at whether pain you feel before emergency surgery affects long-term pain after the surgery. It may help doctors find ways to prevent chronic pain in patients who have emergency orthopedic (bone/joint) or abdominal (belly) surgery.
AmiensAges 18 years+ - NCT06466941Recruiting
Understanding acute pain after surgery
This study surveys surgical patients about their pain and emotional experience to better understand acute pain. You may help by answering questions or sharing your story.
Boston, MassachusettsAges 18 years+ - NCT06379425RecruitingPhase 4
Can pain meds without opioids help you pee sooner after surgery?
This study looks at whether giving a mix of pain medicines (without opioids) before surgery can help you recover faster and avoid needing a catheter after a vaginal repair or sling procedure. It enrolls women having minor gynecologic surgery at the South Shore Surgery Center in New York.
Bay Shore, New YorkAges Any age - NCT06222151Recruiting
Recovering from weight-loss surgery with early walking
This study tests whether starting a supervised walking program soon after weight-loss surgery helps you recover faster. It aims to see if early movement improves your recovery and hospital stay.
Esbjerg, Region SyddanmarkAges 18–70 - NCT06020677Recruiting
Study on Latinx children's pain after surgery
This study looks at how parents manage their child's pain after surgery, focusing on Latinx families who speak Spanish at home. By understanding these experiences, doctors hope to improve pain care for children.
Orange, CaliforniaAges 2–12 - NCT04439552Recruiting
MRI study during cornea cross-linking for keratoconus
This trial uses an MRI scan (and a close-up eye scan) to study what happens in the cornea during treatment for keratoconus. It may help doctors better understand how treatment works and who benefits most.
Boston, MassachusettsAges 8–35 - NCT06320041RecruitingPhase 4
Oliceridine for pain after orthopedic surgery
This trial tests a new painkiller called oliceridine for moderate to severe pain after orthopedic surgery. It may help you recover more comfortably with fewer side effects.
Yiwu, ZhejiangAges 18–100 - NCT07805928Recruiting
A guided pain plan after rib remodeling surgery
This study tests a step-by-step pain management plan guided by your pain scores after rib remodeling surgery. The plan uses a mix of medications to reduce pain safely and may help you recover with less discomfort.
BogotáAges 18–55 - NCT07810816Recruiting
Genetic testing for personalized pain relief after surgery
This study looks at how your genes affect your body's response to tramadol, a painkiller given through a pump after surgery. The goal is to see if your genetic makeup influences pain relief and side effects, which could help personalize pain treatment in the future.
Medellín, AntioquiaAges 18 years+ - NCT06381063RecruitingPhase 3
Anti-inflammatory for heart surgery
This trial is testing whether a non-steroidal anti-inflammatory drug (NSAID) given during heart surgery can reduce complications. It's for people having planned open-heart surgery with a heart-lung machine.
AmiensAges 18 years+ - NCT07831096Recruiting
Nerve block comparison for shoulder surgery pain relief
This study compares two types of nerve blocks to see which one provides better pain relief after outpatient shoulder surgery. Participants will receive one of the two blocks, and the study will track their pain and recovery.
Varese, ItalyAges 18 years+ - NCT07134660Recruiting
Comparing two numbing medicines for lung surgery pain
This study compares two types of numbing medicine (liposomal vs. hydrochloride bupivacaine) injected near the ribs during lung surgery. The goal is to see which one provides better pain relief after the operation.
ShanghaiAges 18–80 - NCT07463430Enrolling by invitationPhase 4
Suzetrigine for pain after non-mastectomy breast surgery
This trial tests a new pain medication, suzetrigine, for people having breast surgery (not mastectomy) who are expected to have moderate pain. It checks if this drug works well compared to standard options.
San Diego, CaliforniaAges 18 years+ - NCT07271849RecruitingPhase 4
Timing of Nalbuphine for Pain and Blood Pressure in Older Knee Surgery Patients
This study tests whether giving the pain medicine nalbuphine at different times during knee replacement surgery affects blood pressure and pain control in older adults. It may help find the best timing to reduce pain and keep vital signs stable.
Jinan, ShandongAges 65–90 - NCT07200544RecruitingPhase 4
Meloxicam for skin cancer surgery pain
This study tests if meloxicam, an anti-inflammatory painkiller, helps control pain after Mohs surgery for skin cancer. It aims to reduce the need for stronger opioid pain medicines.
Oklahoma City, OklahomaAges 18–110
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Common questions
- Are there clinical trials for postoperative pain, acute?
- Yes. Clin2 currently lists 91 recruiting postoperative pain, acute studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative pain, acute trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative pain, acute trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain
- Postoperative Pain Management
- Chronic Postoperative Pain
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.