Clinical trials
Postoperative Pain Management clinical trials
Below are recruiting postoperative pain management clinical trials, each written for real people, not researchers. We’re tracking 122 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07021105Enrolling by invitation
Comparing nerve blocks for pain after gynecological surgery
This study tests two different types of nerve blocks (called 'plain blocks') to see which one works better for controlling pain after major gynecological surgery. You would receive one of the blocks before surgery, and then use a pump you control to get extra pain medicine as needed.
Adana, SarıçamAges 18–69 - NCT06996561RecruitingPhase 2/Phase 3
How your genes affect pain relief after surgery
This study looks at how your genes might affect pain relief from a medication called nalbuphine after abdominal or pelvic surgery. It aims to personalize pain management based on your genetic makeup.
Karachi, SindhAges 18–70 - NCT06937853Recruiting
Genes and painkiller response for tooth pain
This trial tests whether your genes affect how well a common painkiller (NSAID) works for tooth pain after a root canal procedure. It may help find the best pain relief for you.
Erzurum, ErzurumAges 18–65 - NCT06925152RecruitingPhase 4
Nerve block for C-section pain in complex surgery history
This study tests a targeted numbing injection (a nerve block) in the belly wall during C-sections to improve pain control and recovery for people who have had multiple or complex abdominal surgeries. It aims to see if this approach reduces the need for strong pain medicines.
Memphis, TennesseeAges 18–50 - NCT06878014RecruitingPhase 4
Morphine for pain relief after hip replacement surgery
This trial tests different doses of morphine given during spinal anesthesia to find the safest and most effective way to control pain after hip replacement surgery. If you are having a total hip replacement, you may be able to join.
Sosnowiec, Silesian VoivodeshipAges 18–75 - NCT06797973RecruitingPhase 4
Morphine for pain after planned cesarean section
This trial studies whether giving a small dose of morphine into the spinal fluid during a planned cesarean section helps with pain after surgery. It aims to find a safe and effective way to manage pain for new mothers.
AarhusAges 18 years+ - NCT06785389Recruiting
How fear before surgery affects pain and recovery
This study looks at how feeling scared or anxious before surgery might affect your pain and recovery afterward. It aims to help improve care for future patients.
Las Palmas de Gran Canaria, Las PalmasAges 18 years+ - NCT06381063RecruitingPhase 3
Anti-inflammatory for heart surgery
This trial is testing whether a non-steroidal anti-inflammatory drug (NSAID) given during heart surgery can reduce complications. It's for people having planned open-heart surgery with a heart-lung machine.
AmiensAges 18 years+ - NCT06515691Recruiting
Nerve block for pain after weight loss surgery
This study tests a nerve block (an injection near the nerves) to see if it helps reduce pain after laparoscopic sleeve gastrectomy. The block is called a modified thoracoabdominal nerve plane block, and it may lead to better pain control and recovery.
Istanbul, BagcilarAges 18–65 - NCT06353529RecruitingPhase 4
Pain management after pituitary tumor surgery
This study tests a nerve block (called sphenopalatine ganglion block) for pain relief after pituitary tumor surgery through the nose. It aims to see if this block helps manage pain and reduces the need for other pain medicines.
Hamilton, OntarioAges 18–100 - NCT05315596Enrolling by invitation
Tracking pain and recovery answers after surgery
This study checks how patients report pain and recovery over time after surgery. It may help improve how hospitals understand and manage pain after operations.
JenaAges 18 years+ - NCT05231460Enrolling by invitationPhase 4
Pain plan study for people before bariatric surgery
This study tests a specific pain-management plan for people who are scheduled for sleeve gastrectomy (done by laparoscopy or robotics). The goal is to find how to control pain safely around the time of surgery while avoiding certain risks and medication issues.
Phoenix, ArizonaAges 18 years+ - NCT04130464RecruitingPhase 4
Analgesic placed inside the belly for after-surgery pain
This study tests whether placing a pain medicine inside the abdomen during hysterectomy can reduce postoperative pain. It targets people having specific types of minimally invasive hysterectomy for non-cancer reasons.
Washington D.C., District of ColumbiaAges 18–65 - NCT03737292RecruitingPhase 4
Numbing medicine for chest surgery pain after small lung operations
This trial tests whether a long-lasting numbing shot (liposomal bupivacaine) works better than a regular numbing shot (plain bupivacaine) for pain after minimally invasive chest surgery. It may help you have less post-surgery pain and potentially use less pain medication.
Hershey, PennsylvaniaAges 18 years+ - NCT07706348RecruitingPhase 1/Phase 2
Pain relief with ondansetron and lidocaine after abdominal cancer surgery
This trial tests if rinsing the belly with ondansetron (a nausea medicine) and lidocaine (a numbing medicine) during surgery can reduce pain afterward. It is for people having major lower abdominal cancer surgery who are otherwise healthy.
AsyutAges 20–70 - NCT07680998Recruiting
Pain monitor device for recovery after day surgery
This trial tests a device that monitors pain and recovery after outpatient surgery. It may help manage pain more safely and improve your comfort after you go home.
Nîmes, GardAges 18 years+ - NCT07394816Recruiting
Can ultrasound-guided pain blocks reduce lung complications after abdominal surgery?
This study tests whether using ultrasound-guided pain blocks (fascial plane blocks) during major abdominal surgery can reduce lung complications after surgery, especially in older adults. It may offer better pain control and faster recovery.
Yenimahalle, AnkaraAges 65 years+ - NCT07393139Recruiting
Pain after arm or leg amputation
This study looks at pain in the days right after a limb amputation surgery. It aims to better understand and manage early pain, which could help improve recovery.
BolognaAges 18 years+ - NCT07197710Recruiting
Imagined acupuncture for pain after spine surgery
This trial tests if imagining acupuncture, guided by a video, can help reduce pain after spinal surgery. It is for adults having their first spine surgery on one or two bones.
Boston, MassachusettsAges 18 years+ - NCT07113483RecruitingPhase 3
Remimazolam vs. Midazolam for sedation in older adults having orthopedic surgery
This trial compares two sedatives, remimazolam and midazolam, to see which one leads to better recovery of thinking skills after orthopedic surgery. It is for people aged 65 and older who are having surgery on a bone or joint while awake but relaxed.
BucharestAges 65 years+ - NCT07480278Recruiting
Pain relief after back surgery: two injections compared
This trial tests two different injection methods to see which one provides better pain relief after lower back surgery. If you are having a microdiscectomy, this study may help determine the best way to manage your post-operative pain.
Bursa, NilüferAges 18–65 - NCT06845215Recruiting
Pain block comparison for abdominoplasty recovery
This trial compares two types of nerve blocks (TAP and ESP) to see which provides better pain relief after tummy tuck surgery. Both are injections near the abdominal muscles that numb the area, and you'll also have a patient-controlled pain pump.
Ankara, KeçiörenAges Any age - NCT07269106RecruitingPhase 4
Testing anrikefon for pain relief after eye surgery
This trial tests a new painkiller called anrikefon for people having eye surgery under general anesthesia. It aims to see if it's safe and effective for controlling pain after the procedure.
Guangzhou, GuangdongAges 18–70 - NCT06574269RecruitingPhase 2
Study on TLC590 for pain after surgery
This trial tests a new pain medicine, TLC590, for people having one of several common surgeries, like bunion removal, hernia repair, breast augmentation, knee replacement, or tummy tuck. The goal is to see if it helps manage pain after the procedure.
Bellaire, TexasAges 18–70
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Common questions
- Are there clinical trials for postoperative pain management?
- Yes. Clin2 currently lists 122 recruiting postoperative pain management studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative pain management trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative pain management trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.